389 results on '"Bukau, Bernd"'
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2. J-domain proteins : From molecular mechanisms to diseases
3. Takashi Yura—in memory of an inspiring pioneer of the bacterial heat shock response
4. Role of J-domain Proteins in Yeast Physiology and Protein Quality Control
5. A unique chaperoning mechanism in class A JDPs recognizes and stabilizes mutant p53
6. Combinations of slow-translating codon clusters can increase mRNA half-life in Saccharomyces cerevisiae
7. The Diverse Functions of Small Heat Shock Proteins in the Proteostasis Network
8. Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue
9. Nα-terminal acetylation of proteins by NatA and NatB serves distinct physiological roles in Saccharomyces cerevisiae
10. Cooperative amyloid fibre binding and disassembly by the Hsp70 disaggregase
11. Pairs of amino acids at the P- and A-sites of the ribosome predictably and causally modulate translation-elongation rates
12. Selective 40S Footprinting Reveals Cap-Tethered Ribosome Scanning in Human Cells
13. Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species
14. Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions
15. Functional diversity between HSP70 paralogs caused by variable interactions with specific co-chaperones
16. Molecular dissection of amyloid disaggregation by human HSP70
17. HSP40 proteins use class-specific regulation to drive HSP70 functional diversity
18. GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile
19. Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor
20. Protein Disaggregation in Multicellular Organisms
21. Processive extrusion of polypeptide loops by a Hsp100 disaggregase
22. Cellular Handling of Protein Aggregates by Disaggregation Machines
23. Stand-alone ClpG disaggregase confers superior heat tolerance to bacteria
24. Trigger Factor Binds to Ribosome-Signal-Recognition Particle (SRP) Complexes and Is Excluded by Binding of the SRP Receptor
25. Role of sHsps in organizing cytosolic protein aggregation and disaggregation
26. The growing world of small heat shock proteins: from structure to functions
27. MecA, an Adaptor Protein Necessary for ClpC Chaperone Activity
28. Role for ribosome-associated complex and stress-seventy subfamily B (RAC-Ssb) in integral membrane protein translation
29. Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux
30. Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding
31. DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4
32. The HSP110/HSP70 disaggregation system generates spreading‐competent toxic α‐synuclein species
33. Binding Specificity of Escherichia coli Trigger Factor
34. Sequential Mechanism of Solubilization and Refolding of Stable Protein Aggregates by a Bichaperone Network
35. Mechanism of Regulation of Hsp70 Chaperones by DnaJ Cochaperones
36. Mutations in the DnaK Chaperone Affecting Interaction with the DnaJ Cochaperone
37. Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling
38. The Human DnaJ Homologue dj2 Facilitates Mitochondrial Protein Import and Luciferase Refolding
39. Escherichia coli Trigger Factor is a Prolyl isomerase that Associates with Nascent Polypeptide Chains
40. Chaperone Function on Crete: A Meeting Report
41. Bacterial and Yeast AAA + Disaggregases ClpB and Hsp104 Operate through Conserved Mechanism Involving Cooperation with Hsp70
42. Trigger Factor Reduces the Force Exerted on the Nascent Chain by a Cotranslationally Folding Protein
43. Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis
44. Human Hsp70 Disaggregase Reverses Parkinson’s-Linked α-Synuclein Amyloid Fibrils
45. Spatially Organized Aggregation of Misfolded Proteins as Cellular Stress Defense Strategy
46. Operon structure and cotranslational subunit association direct protein assembly in bacteria
47. Finding nascent proteins the right home: A protein complex prevents promiscuous targeting of nascent polypeptides in the cell
48. Co-translational mechanisms of protein maturation
49. Hsp70 displaces small heat shock proteins from aggregates to initiate protein refolding
50. Coordination of Translational Control and Protein Homeostasis during Severe Heat Stress
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