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Héloïse Rouzé1,2, Marie Viprey1,2, Samuel Allemann2, Alexandra L Dima2, Pascal Caillet3, Angélique Denis1, Stéphanie Poupon-Bourdy1, Boubou Camara4, Catherine Llerena5, Philippe Reix6, Isabelle Durieu2,7, Quitterie Reynaud2,7, Sandrine Touzet1,2 1Public Health Department, Hospices Civils de Lyon, Lyon, France; 2HESPER Lab-EA 7425, Université de Lyon-Université Claude Bernard Lyon 1, Lyon, France; 3Department of Clinical Pharmacology, CHU de Nantes, Nantes, France; 4Pulmonary Department, Adult CF Center, CHU de Grenoble, Grenoble, France; 5Pediatric Pulmonology Department, Pediatric CF Center, CHU de Grenoble, Grenoble, France; 6Pediatric Pulmonology Department, Pediatric CF Center, Hôpital Femme-Mère-Enfant, Hospices Civils de Lyon, Lyon, France; 7Department of Internal Medicine, Adult Cystic Fibrosis Care Center, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, FranceCorrespondence: Héloïse RouzéHospices Civils de Lyon, Pôle de Santé Publique, Bâtiment A, 6ème étage, 162 Avenue Lacassagne 69003 Lyon, FranceTel +33 47 211 5132Email heloise.rouze@chu-lyon.frBackground: Cystic fibrosis (CF) is a life-shortening genetic condition that usually affects several organs and involves significant treatment burden. Adherence to medication is important for successful CF management.Objective: To describe medication adherence according to age, therapeutic class, and pharmaceutical form in adults and children followed in four regional CF centers in France.Methods: We conducted a cross-sectional study with non-transplanted patients followed in two adult and two pediatric centers during 2015 who were covered by the French National Health Insurance (NHI). Sociodemographic, clinical, hospitalization, and prescription data were collected from patient medical records. Medication dispensations were extracted from the regional French NHI database. Adherence was calculated over 12 months using continuous medication availability (CMA) accounting for dose adjustments and hospitalizations. Drug-specific CMA was computed in R with the AdhereR package for each medication prescribed more than 3 months, which was averaged to obtain a composite CMA score (cCMA) for all treatments and per therapeutic class as well as pharmaceutical form for each patient.Results: A total of 228 patients were included. The number of chronic medications increased with age (r=0.50, p

This article reports on the first occurrence of mango dieback disease caused by the fungus Lasiodiplodia brasiliense in Côte d'Ivoire. Surveys conducted in 2020 revealed the presence of mango dieback symptoms, including leaf, twig, and branch drying, as well as tree death. Isolation and analysis of the fungus confirmed its identity as Lasiodiplodia brasiliense. The pathogenicity of the fungus was also demonstrated through a greenhouse experiment. This study highlights the need for further research to understand the variation among isolates and develop effective control strategies. The research was funded by the Partnership for Skills in Applied Sciences, Engineering, and Technology and received support from the Fondation Louis Omer DECUGIS and the Société Internationale d'Importation. [Extracted from the article]

Yam (Dioscorea spp) occupies an important place in the diet of the populations of Côte d’Ivoire. It is a real source of starch and therefore generates enormous commercial potential. However, the decrease in production due to pest attacks represents a real threat to this crop. This study was conducted with the aim of improving yam production in Côte d’Ivoire. To do so, isolations carried out on yam leaves showing symptoms of foliar diseases have allowed us to identify 9 fungal genera. These were Colletotrichum sp., Fusarium sp., Pestalotiopsis sp., Pestalotia sp., Botryodiplodia sp., Aspergillus sp., Mucor sp., Curvularia sp. and Phytophtora sp. Among these fungi, the genus Colletotrichum sp. was the most isolated with a rate of 56% followed by the Fusarium and Pestalotia genera (8%). Pathogenicity tests performed on healthy leaves of two yam varieties revealed that the Dioscorea alata is more susceptible to fungi compared to Dioscorea rotundata. The largest average diameter of necrosis was caused by Pestalotiopsis sp. (5.97 cm) on the Dioscorea alata variety while the smallest was caused by Colletotrichum sp.9 on Dioscorea rotundata (0.5 cm). Combatting these fungi need to be developed for effective management of leaf diseases of yam in Côte d’Ivoire.

Purpose. To analyze the peculiarities of the use of ICT and their structural components. To formulate requirements for strategic decision-making systems. To identify the impact of ICT on creation of new opportunities and threats. To form a basic structural scheme of using ICT in strategic decision-making. Methodology. Methods of critical and comparative analysis were used to determine the topic and purpose of the study. Method of system analysis was used for the formation of the basic structural scheme of ICT when making strategic decisions. The method of induction and deduction was used to study the features of ICT and their structural components. Idealization and formalization method – to analyze the problems and threats associated with the use of ICT. Method of analysis and synthesis – to identify and study in detail the indirect effects of related industries on the formation of strategic decision-making. Findings. Requirements for decision support and decision-making systems, their software components as well as for the quality of data that determines the relevance of decisions were formulated. The need is pointed out to create powerful information centers that can serve a significant number of enterprises, combining their use with a distributed network of enterprise information centers. The analysis of the dynamics of gas consumption confirmed the situational nature of strategic decision-making by certain consumer groups and the weak level of ICT use. Originality. The basic structural scheme of ICT uses in making strategic decisions by enterprise management is formed. The reasons for the lack of generalized principles of strategic digital transformation of enterprises are identified. It is established that the state and tendencies of changes of branches which influence the activity of the analyzed enterprise are though indirect but significant and should be subject to the strategic analysis. Practical value. The proposed basic structural scheme of ICT use can be used as a model in the implementation of ICT at the enterprise. The results of theoretical research and practical testing of the proposed approach can be widely used for the analysis of the dynamics of natural gas consumption. [ABSTRACT FROM AUTHOR]

Copyright of Mali Médical is the property of Mali Medical, Faculte de Medecine, de Pharmacie et d'Odonto-stomatologie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Les bronchectasies, ou dilatations des bronches, sont des anomalies anatomiques primitives ou secondaires. Leur compréhension est de plus en plus précise grâce à l'augmentation récente du nombre d'études portant sur leur physiopathologie, leur prise en charge et leurs étiologies. À l'heure actuelle, plusieurs pathologies sont associées aux bronchectasies, soit comme une complication de la pathologie initiale, soit à cause de l'existence d'un terrain clinique commun. L'étiologie d'une dilatation des bronches définit sa prise en charge extrarespiratoire, mais aussi le pronostic de l'atteinte pulmonaire et les traitements spécifiques à mettre en place. Il est donc crucial d'adresser un patient porteur de dilatations des bronches à un pneumologue, et de cerner le plus efficacement possible la pathologie causale. Nous établirons succinctement ici l'avancement actuel des connaissances concernant les bronchectasies, leurs étiologies et détaillerons les recommandations en cours pour les explorations initiales. [ABSTRACT FROM AUTHOR]

Copyright of Mali Médical is the property of Mali Medical, Faculte de Medecine, de Pharmacie et d'Odonto-stomatologie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)