111 results on '"Collett, Johnny"'
Search Results
2. Physical, cognitive, and social triggers of symptom fluctuations in people living with long COVID: an intensive longitudinal cohort study
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Bakerly, Nawar D., Balasundaram, Kumaran, Ball, Megan, Barahona, Mauricio, Casson, Alexander, Clarke, Jonathan, Cook, Karen, Cooper, Rowena, Curcin, Vasa, Darbyshire, Julie, Davies, Helen E., Dawes, Helen, de Lusignan, Simon, Delaney, Brendan, Echevarria, Carlos, Elkin, Sarah, Espinosa Gonzalez, Ana Belen, Evans, Rachael, Evans, Sophie, Falope, Zacchaeus, Glampson, Ben, Goodwin, Madeline, Greenhalgh, Trish, Greenwood, Darren C., Halpin, Stephen, Harris, Juliet, Hinton, Will, Horton, Mike, Jones, Samantha, Kwon, Joseph, Lee, Cassie, Lovett, Ashliegh, Mansoubi, Mae, Masey, Victoria, Master, Harsha, Mayer, Erik, Meza-Torres, Bernardo, Milne, Ruairidh, Mir, Ghazala, Morris, Jacqui, Mosley, Adam, Mullard, Jordan, O'Connor, Daryl, O'Connor, Rory, Osborne, Thomas, Parkin, Amy, Petrou, Stavros, Pick, Anton, Prociuk, Denys, Rayner, Clare, Rebane, Amy, Rogers, Natalie, Scott, Janet T., Sivan, Manoj, Smith, Adam B., Smith, Nikki, Tucker, Emma, Tucker-Bell, Ian, Williams, Paul, Winch, Darren, Wood, Conor, Mansoubi, Maedeh, Bhatia, Aishwarya, Collett, Johnny, Dawes, Joanna, Ezekiel, Leisle, Leveridge, Phaedra, Muhlhausen, Willie, Read, Flo, Tucker–Bell, Ian, Vashisht, Himanshu, Ward, Tomás, and O'Connor, Daryl B. more...
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- 2024
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Catalog
3. Development of a single-item physical activity intention measure for adults with intellectual disabilities: Evidence of validity and reliability
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Dairo, Yetunde Marion, Collett, Johnny, and Dawes, Helen
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- 2024
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4. The effects of cognitive-motor interference on walking performance in adolescents with low balance
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Weedon, Benjamin David, Esser, Patrick, Collett, Johnny, Izadi, Hooshang, Inacio, Mario, Joshi, Shawn, Meaney, Andy, Delextrat, Anne, Kemp, Steve, and Dawes, Helen
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- 2024
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5. The positioning information that should be provided to caregivers of adults with a physical disability on supply of custom-contoured seating, a Delphi study.
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Hanley, Ruth and Collett, Johnny
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SCALE analysis (Psychology) , *PRODUCT design , *CAREGIVERS , *ASSISTIVE technology , *THEMATIC analysis , *COMMUNICATION , *DELPHI method , *PEOPLE with disabilities - Abstract
Purpose: This research aims to identify information that is important to provide on supply of custom-contoured seating. The way this information would be best communicated is also of interest. A two-round e-Delphi study was utilised to explore consensus. A panel of stakeholders from Ireland including experts in positioning clients in custom-contoured seating and caregivers were recruited. The first round consisted of open-ended questions and was analysed using thematic analysis. The second round employed a rating technique and 7-point Likert scale. Consensus was set a priori at 70% agreement. The way information should be communicated and by whom was rated in order of preference. Materials and methods: Fifteen participants were recruited, nine clinicians and four caregivers. Fifty-two statements under six themes (transfers = 10, positioning = 22, pressure care = 4, general use = 4, post-supply follow-up = 8, functional activity = 4) were generated in round 1 by 13/15 participants. Round 2 was completed by 10/15. 49/52 statements reached consensus and were deemed important. The ways information should be communicated and by whom was identified. Caregivers want individualised information whereas clinicians preferred a more generic approach. Results and conclusions: There was a high degree of consensus on what information is required to support caregivers. The topics demonstrate the extensive information that should be provided. The preferred delivery method for primary caregivers was hands-on training with the opportunity to practice and take videos. Stakeholders differed in how they would prefer information delivered. Further research should evaluate the method of delivering training and its effectiveness. IMPLICATIONS FOR REHABILITATION: Caregivers report a lack of guidance on postural management, which exacerbates their own health problems and results in underutilization of positioning equipment. Caregivers should be provided with information on transfers, positioning, pressure care, general chair use, post-supply follow-up, and the impact on functional activities when a new custom contoured seat is supplied. The preferred method of providing information to primary caregivers is to use hands-on training with the opportunity to practice and take videos during the supply appointment. Personalised information booklets or group training sessions may be most appropriate for additional caregivers. [ABSTRACT FROM AUTHOR] more...
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- 2025
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6. Exploring the usefulness of real-time digitally supported fatigue monitoring in fatigue management: Perspectives from occupational therapists and brain injury survivors.
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Ezekiel, Leisle, Wilding, Harriet, Dearling, Jeremy, Collett, Johnny, and Dawes, Helen
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DIGITAL technology ,SOCIAL media ,SELF-management (Psychology) ,RESEARCH funding ,QUALITATIVE research ,SMARTPHONES ,FATIGUE (Physiology) ,DIGITAL health ,OCCUPATIONAL therapists ,INTERVIEWING ,DESCRIPTIVE statistics ,BEHAVIOR ,JUDGMENT sampling ,OCCUPATIONAL therapy ,THEMATIC analysis ,ATTITUDES of medical personnel ,RESEARCH methodology ,QUALITY of life ,INFORMED consent (Medical law) ,PATIENT monitoring ,BRAIN injuries ,PHYSICAL activity ,ALGORITHMS ,DISEASE complications - Abstract
Introduction: Persistent fatigue after acquired brain injury (ABI) needs long-term self-management. Self-monitoring supports self-management and informs the use of fatigue management strategies. Using ecological momentary assessment to monitor fatigue offers a data-driven approach to managing fatigue. Aims: To explore the usefulness of self-monitoring fatigue in real-time, using ecological momentary assessment to support self-management, from the perspective of people with ABI and occupational therapists. Methods: People with ABI monitoried their fatigue by wearing a Fitbit and completing six surveys a day on their phone for 6 days. Think aloud and semi-structured interviews elicited views on self-monitoring and the data generated. Transcripts were analysed using reflexive thematic analysis. Results: Four themes were developed from people with ABI (n = 9): (1) Attending to experience, (2) making sense of data, (3) the relationship between fatigue and activity, (4) implications for daily life. Three themes from occupational therapists (n = 5): (1) Challenges of using of data, (2) perceived benefits of self-monitoring, (3) viewing data in relation to their understanding of fatigue. Conclusion: Data generated in real-time challenged perspectives on fatigue and fatigue management. These insights may help people with ABI and their clinicians to plan personalised strategies for fatigue management and evaluate its impact on daily living. [ABSTRACT FROM AUTHOR] more...
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- 2024
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7. The effectiveness of prehabilitation interventions on biopsychosocial and service outcomes pre and post upper gastrointestinal surgery: a systematic review.
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Stiger, Robyn J., Williams, Mark A., Gustafson, Owen D., Woods, Alyson, and Collett, Johnny
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ANXIETY prevention ,PSYCHOTHERAPY ,MEDICAL information storage & retrieval systems ,PULMONARY function tests ,PATIENT compliance ,RESEARCH funding ,EXERCISE ,ANAEROBIC threshold ,SELF-efficacy ,PREHABILITATION ,EXERCISE therapy ,CINAHL database ,FUNCTIONAL assessment ,PATIENT readmissions ,PREOPERATIVE care ,TREATMENT effectiveness ,HEALTH surveys ,BRIEF Pain Inventory ,DIGESTIVE organ surgery ,SYSTEMATIC reviews ,MEDLINE ,STRENGTH training ,CARDIOPULMONARY system ,EXPIRATORY flow ,SURGICAL complications ,COMBINED modality therapy ,QUALITY of life ,ONLINE information services ,BODY movement ,EXERCISE tests ,OXYGEN consumption ,LENGTH of stay in hospitals ,GASTROINTESTINAL diseases ,PSYCHOLOGY information storage & retrieval systems ,BIOPSYCHOSOCIAL model ,CANCER patient rehabilitation ,GRIP strength ,REHABILITATION - Abstract
Purpose: This review synthesised the evidence for the effect of prehabilitation interventions on biopsychosocial and service outcomes. Materials and Methods: A systematic review was conducted. 10 databases were searched to December 2023. Prospective experimental studies exploring prehabilitation interventions in adults undergoing upper gastrointestinal surgery were included. Prehabilitation was any preoperative intervention to improve physical or psychological outcomes. Included studies required a comparator group or alternative preoperative intervention as well as baseline, presurgical and postoperative assessment points. Study quality was assessed using the Cochrane risk of bias tool (v.2). Data synthesis was narrative (SWiM guidance). Results: 6028 studies were screened, with 25 studies included. Prehabilitation interventions were: inspiratory muscle training (five studies n = 450); exercise (nine studies n = 683); psychological (one study n = 400); and nutritional (ten studies n = 487). High quality studies showed preoperative improvements in impairments directly targeted by the interventions. Generally, these did not translate into functional or postoperative improvements, but multimodal interventions were more promising. Conclusion: Current evidence supports prehabilitation as safe to preserve or improve preoperative function. Heterogeneity in outcomes and variable study quality means definitive conclusions regarding interventions are not yet possible, limiting implementation. Agreement of clinical outcomes and cost effectiveness evaluation is required. IMPLICATIONS FOR REHABILITATION: Prehabilitation interventions are safe and when combined optimally may preserve or improve preoperative function in patients undergoing upper gastrointestinal surgery. Multimodal interventions (including exercise, nutritional, and psychological components) showed promise which supports the delivery of prehabilitation by multidisciplinary teams. Development of a core outcome set and agreed time points for both preoperative and postoperative outcomes is needed for effective evidence synthesis. Focus on long term outcomes is necessary to determine cost effectiveness and commissioning of resources. [ABSTRACT FROM AUTHOR] more...
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- 2024
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8. A cross sectional assessment of nutrient intake and the association of the inflammatory properties of nutrients and foods with symptom severity in a large cohort from the UK Multiple Sclerosis Registry
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Coe, Shelly, Tektonidis, Thanasis G., Coverdale, Clare, Penny, Sarah, Collett, Johnny, Chu, Bernard T.Y., Izadi, Hooshang, Middleton, Rod, and Dawes, Helen
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- 2021
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9. Evaluation of speed-accuracy trade-off in a computer task to identify motor difficulties in individuals with Duchenne Muscular Dystrophy - A cross-sectional study
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da Silva, Talita Dias, Ribeiro-Papa, Denise Cardoso, Coe, Shelly, Malheiros, Silvia Regina Pinheiro, Massetti, Thais, Meira Junior, Cassio de Miranda, Nicolai Ré, Alessandro Hervaldo, Collett, Johnny, Monteiro, Carlos Bandeira de Mello, and Dawes, Helen more...
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- 2020
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10. Factors Associated With Participation in Life Situations for Adults With Stroke: A Systematic Review
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Ezekiel, Leisle, Collett, Johnny, Mayo, Nancy E., Pang, Lori, Field, Leanne, and Dawes, Helen
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- 2019
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11. Sensorimotor functioning changes in response to global exercise versus handwriting upper limb exercise training in Parkinson's disease, results from a phase II randomised controlled trial.
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Moraes, Íbis Ariana Peña de, Collett, Johnny, Silva, Talita Dias da, Franssen, Marloes, Mitta, Surabhi, Zalewski, Paweł, Meaney, Andy, Wade, Derick, Izadi, Hooshang, Winward, Charlotte, Monteiro, Carlos Bandeira de Mello, and Dawes, Helen more...
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EXERCISE therapy , *PARKINSON'S disease , *RANDOMIZED controlled trials , *HANDWRITING , *EVERYDAY life , *REACTION time - Abstract
Introduction: People with Parkinson's disease (PwPD) present motor alterations which can impact daily life tasks that require speed and/or accuracy of movement. Objective: A sub analysis of NCT01439022, aiming to estimate the extent to which two different exercise training protocols (global and handwriting upper limb exercise training) impact reaction time, travel speed, and accuracy in PwPD. Methods: Seventy PwPD, right-side dominant were randomised 1:1 into two six-month training protocol groups; 35 PwPD performed global exercise training and 35 performed specific training (handwriting upper limb exercise movements). Assessments of speed-accuracy and trade-off were carried out at baseline, after 3 and 6 months of training, and at a 12-month follow-up. The current study used data from a previous publication of a randomised controlled trial that included a 6-month self-managed community exercise programme for PwPD. For the present study we included only the participants who completed the Fitts' task during the baseline assessment. Results: In the upper limb assessments, no main effects were found for the number of touches, but the exercise group showed a marginal increase over time on the left side. Error averages on the left side decreased significantly for the exercise group from baseline to 6 and 12 months. The exercise group also presented a lower Error CoV and the Reaction Time CoV increased on the right side. Significant findings for Fitts r on the left side indicated lower values for the exercise group, with improvements continuing at 12 months. Conclusion: We report the potential of global exercise interventions to facilitate improvements in reaction time and travel speed, as well as other motor control metrics, with lasting effects at 12 months, particularly on the non-dominant side. [ABSTRACT FROM AUTHOR] more...
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- 2024
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12. Positive risk-taking within social care for adults with physical disabilities: A review of guidelines in practice in England.
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Field, Leanne, Nagy, Liana, Knaggs, Tarnya, and Collett, Johnny
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MEDICAL protocols ,RISK assessment ,RISK-taking behavior ,PROFESSIONAL practice ,CONFIDENCE ,DECISION making in clinical medicine ,SOCIAL support ,PEOPLE with disabilities - Abstract
Introduction: Despite practice guidelines, professionals do not feel confident in implementing positive risk-taking. This may be due to the guidance provided. Method: A scoping review of current organisational guidance for the professional practice of positive risk-taking within Adult Social Care services for people with a physical disability. Guidelines were obtained from Local Authorities in England in October 2020. The data were extracted using TIDieR to describe positive risk-taking as an intervention. The quality of the guidelines was assessed using AGREE II. Findings: In all, 36 Local Authorities responded out of 106 contacted. A total of 21 documents were included for review. Substantial variability was found in terminology, definitions and risk grading between documents. The greatest consistency was found in how to implement a positive risk-taking intervention. Consistency was also found in the policy that documents cited. There was little reference to evidence to support intervention components. Overall, AGREE II quality scores were low and stakeholder involvement, specifically with regard to the views and preferences of service users, was largely absent. Conclusion: There is a need for a greater consensus to guide the professional practice of positive risk-taking. Determining the extent of current evidence and establishing an evidence base may facilitate more consistent guidelines and support professionals' confidence in implementing positive risk-taking. [ABSTRACT FROM AUTHOR] more...
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- 2024
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13. Motor learning in developmental coordination disorder: behavioral and neuroimaging study.
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Al-Yahya, Emad, Esser, Patrick, Weedon, Benjamin D., Joshi, Shawn, Yan-Ci Liu, Springett, Daniella N., Salvan, Piergiorgio, Meaney, Andy, Collett, Johnny, Inacio, Mario, Delextrat, Anne, Kemp, Steve, Ward, Tomas, Izadi, Hooshang, Johansen-Berg, Heidi, Ayaz, Hasan, and Dawes, Helen more...
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Developmental coordination disorder (DCD) is characterized by motor learning deficits that are poorly understood within whole-body activities context. Here we present results of one of the largest non-randomized interventional trials combining brain imaging and motion capture techniques to examine motor skill acquisition and its underpinning mechanisms in adolescents with and without DCD. A total of 86 adolescents with low fitness levels (including 48 with DCD) were trained on a novel stepping task for a duration of 7 weeks. Motor performance during the stepping task was assessed under single and dualtask conditions. Concurrent cortical activation in the prefrontal cortex (PFC) was measured using functional near-infrared spectroscopy (fNIRS). Additionally, structural and functional magnetic resonance imaging (MRI) was conducted during a similar stepping task at the beginning of the trial. The results indicate that adolescents with DCD performed similarly to their peers with lower levels of fitness in the novel stepping task and demonstrated the ability to learn and improve motor performance. Both groups showed significant improvements in both tasks and under single- and dual-task conditions at post-intervention and follow-up compared to baseline. While both groups initially made more errors in the Stroop task under dual-task conditions, at follow-up, a significant difference between single- and dual-task conditions was observed only in the DCD group. Notably, differences in prefrontal activation patterns between the groups emerged at different time points and task conditions. Adolescents with DCD exhibited distinct prefrontal activation responses during the learning and performance of a motor task, particularly when complexity was increased by concurrent cognitive tasks. Furthermore, a relationship was observed between MRI brain structure and function measures and initial performance in the novel stepping task. Overall, these findings suggest that strategies that address task and environmental complexities, while simultaneously enhancing brain activity through a range of tasks, offer opportunities to increase the participation of adolescents with low fitness in physical activity and sports. [ABSTRACT FROM AUTHOR] more...
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- 2024
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14. The Relationship Between Motor Competence Physical Activity Cardiorespiratory Fitness and BMI in UK Adolescents.
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Weedon, Benjamin David, Esser, Patrick, Collett, Johnny, Izadi, Hooshang, Joshi, Shawn, Meaney, Andy, Delextrat, Anne, Kemp, Steve, and Dawes, Helen
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CARDIOPULMONARY fitness ,PHYSICAL activity ,TEENAGERS ,MOTOR ability ,REGRESSION analysis - Abstract
Purpose: This study set out to identify the extent of the relationships between subsections of the Movement Assessment Battery for Children 2nd Edition - MABC2 (manual dexterity, aiming and catching, and balance) to PA, CRF and BMI in adolescents. Methods: Height, BMI, the MABC2, a 20m shuttle run test and wrist-worn accelerometery PA levels (mins) were measured. Multivariable linear regression models, adjusting for sex, height and BMI were used to assess the relationship of the three subsections of the MABC2 with PA, CRF and BMI. Results: A total of 155 adolescents, aged 13-14 years, took part in this study (77 girls, 78 boys). Balance reported significant relationships with moderate to vigorous PA (unstandardised Beta B=0.15, 95%CI 0.02-0.28), vigorous PA (B=0.06, 95%CI 0.02-0.09) and BMI (B=-0.01, 95%CI -0.02-0.005). Balance in addition to aiming and catching skills were both significantly related to adolescent CRF (B=0.30, 95%CI 0.17-0.42 and B=0.29, 95%CI 0.14-0.45, respectively). Conclusion: This study suggests that balance is the strongest correlate skill to achieving the highest intensities of PA and healthier BMI status in adolescents. [ABSTRACT FROM AUTHOR] more...
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- 2024
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15. A Feasibility Study into the Measurement of Physical Activity Levels of Adults with Intellectual Disabilities Using Accelerometers and the International Physical Activity Questionnaire
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Dairo, Yetunde M., Collett, Johnny, and Dawes, Helen
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Background: Few studies have measured physical activity (PA) levels of adults with intellectual disabilities using both objective and subjective methods, but none included individuals with profound intellectual disabilities. To inform effective measurement of PA across the disability spectrum, this study explored: the feasibility of measuring PA levels using the International Physical Activity Questionnaire-short version (IPAQ-s) and a wrist-worn 7-day accelerometer; examined the level of agreement between instruments/raters; and established the recruitment rate. From the literature reviewed, no study has investigated these issues. Materials and Methods: Two-hundred adults with intellectual disabilities from a local authority lists in UK were invited to participate. Participants were administered an accelerometer for seven days and the IPAQ-s (self and carer-reported). Results: Twenty participants with mild to profound intellectual disabilities (20-70 years) were recruited. The response rate was significantly different between home (16%) and residential homes (4%): ?[superscript 2](1) = 7.7, p < 0.05. All participants completed the IPAQ-s but only 15 completed 7-day accelerometer. Self and carer-reported PA had perfect agreement on IPAQ-s, and agreements between instruments using PA guidelines was substantial (k = 0.6, p < 0.05). However, mean moderate-vigorous PA min/week differed between measures at 145 and 207 from IPAQ-s and accelerometer respectively. Conclusions: Recruitment demonstrated a need for better engagement with residential homes. While both the IPAQ-s and accelerometers can be used to evaluate PA levels, the IPAQ-s was more acceptable and carer report was accurate, but it underestimated absolute moderate-vigorous PA levels. These findings indicate that IPAQ-s can be used to measure PA levels, including in those with profound intellectual disabilities. more...
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- 2017
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16. Poor specificity of National Early Warning Score (NEWS) in spinal cord injuries (SCI) population: a retrospective cohort study
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Ahmed, Wail A., Rouse, Alex, Griggs, Katy E., Collett, Johnny, and Dawes, Helen
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- 2020
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17. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
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Adams, Hadie, Agnoletti, Vanni, Allanson, Judith, Amrein, Krisztina, Andaluz, Norberto, Anke, Audny, Antoni, Anna, van As, Arjan Bastiaan, Audibert, Gérard, Azaševac, Antun, Azouvi, Philippe, Azzolini, Maria Luisa, Baciu, Camelia, Badenes, Rafael, Barlow, Karen M, Bartels, Ronald, Bauerfeind, Ursula, Beauchamp, Miriam, Beer, Darcy, Beer, Ronny, Belda, Francisco Javier, Bellander, Bo-Michael, Bellier, Rémy, Benali, Habib, Benard, Thierry, Beqiri, Valzerda, Beretta, Luigi, Bernard, Francis, Bertolini, Guido, Bilotta, Federico, Blaabjerg, Morten, den Boogert, Hugo, Boutis, Kathy, Bouzat, Pierre, Brooks, Brian, Brorsson, Camilla, Bullinger, Monika, Burns, Emma, Calappi, Emiliana, Cameron, Peter, Carise, Elsa, Castaño-León, Ana M, Causin, Francesco, Chevallard, Giorgio, Chieregato, Arturo, Christie, Brian, Cnossen, Maryse, Coles, Jonathan, Collett, Johnny, Della Corte, Francesco, Craig, William, Csato, Gabor, Csomos, Akos, Curry, Nicola, Dahyot-Fizelier, Claire, Dawes, Helen, DeMatteo, Carol, Depreitere, Bart, Dewey, Deborah, van Dijck, Jeroen, Đilvesi, Đula, Dippel, Diederik, Dizdarevic, Kemal, Donoghue, Emma, Duek, Or, Dulière, Guy-Loup, Dzeko, Adelaida, Eapen, George, Emery, Carolyn A, English, Shane, Esser, Patrick, Ezer, Erzsébet, Fabricius, Martin, Feng, Junfeng, Fergusson, Dean, Figaji, Anthony, Fleming, Joanne, Foks, Kelly, Francony, Gilles, Freedman, Stephen, Freo, Ulderico, Frisvold, Shirin K, Gagnon, Isabelle, Galanaud, Damien, Gantner, Dashiell, Giraud, Benoit, Glocker, Ben, Golubovic, Jagoš, Gómez López, Pedro A, Gordon, Wayne A, Gradisek, Primoz, Gravel, Jocelyn, Griesdale, Donald, Grossi, Francesca, Haagsma, Juanita A, Håberg, Asta Kristine, Haitsma, Iain, Van Hecke, Wim, Helbok, Raimund, Helseth, Eirik, van Heugten, Caroline, Hoedemaekers, Cornelia, Höfer, Stefan, Horton, Lindsay, Hui, Jiyuan, Huijben, Jilske Antonia, Hutchinson, Peter J, Jacobs, Bram, van der Jagt, Mathieu, Jankowski, Stefan, Janssens, Koen, Jelaca, Bojan, Jones, Kelly M, Kamnitsas, Konstantinos, Kaps, Rafael, Karan, Mladen, Katila, Ari, Kaukonen, Kirsi-Maija, De Keyser, Véronique, Kivisaari, Riku, Kolias, Angelos G, Kolumbán, Bálint, Kolundžija, Ksenija, Kondziella, Daniel, Koskinen, Lars-Owe, Kovács, Noémi, Kramer, Andreas, Kutsogiannis, Demitri, Kyprianou, Theodoros, Lagares, Alfonso, Lamontagne, François, Latini, Roberto, Lauzier, François, Lazar, Isaac, Ledig, Christian, Lefering, Rolf, Legrand, Valerie, Levi, Leon, Lightfoot, Roger, Lozano, Angels, MacDonald, Stephen, Major, Sebastian, Manara, Alex, Manhes, Pauline, Maréchal, Hugues, Martino, Costanza, Masala, Alessandro, Masson, Serge, Mattern, Julia, McFadyen, Bradford, McMahon, Catherine, Meade, Maureen, Melegh, Béla, Menovsky, Tomas, Moore, Lynne, Morgado Correia, Marta, Morganti-Kossmann, Maria Cristina, Muehlan, Holger, Mukherjee, Pratik, Murray, Lynnette, van der Naalt, Joukje, Negru, Ancuta, Nelson, David, Nieboer, Daan, Noirhomme, Quentin, Nyirádi, József, Oddo, Mauro, Okonkwo, David O, Oldenbeuving, Annemarie W, Ortolano, Fabrizio, Osmond, Martin, Payen, Jean-François, Perlbarg, Vincent, Persona, Paolo, Pichon, Nicolas, Piippo-Karjalainen, Anna, Pili-Floury, Sébastien, Pirinen, Matti, Ple, Horia, Poca, Maria Antonia, Posti, Jussi, Van Praag, Dominique, Ptito, Alain, Radoi, Andreea, Ragauskas, Arminas, Raj, Rahul, Real, Ruben G L, Reed, Nick, Rhodes, Jonathan, Robertson, Claudia, Rocka, Saulius, Røe, Cecilie, Røise, Olav, Roks, Gerwin, Rosand, Jonathan, Rosenfeld, Jeffrey V, Rosenlund, Christina, Rosenthal, Guy, Rossi, Sandra, Rueckert, Daniel, de Ruiter, Godard C W, Sacchi, Marco, Sahakian, Barbara J, Sahuquillo, Juan, Sakowitz, Oliver, Salvato, Gerardo, Sánchez-Porras, Renán, Sándor, János, Sangha, Grinder, Schäfer, Nadine, Schmidt, Silke, Schneider, Kathryn J, Schnyer, David, Schöhl, Herbert, Schoonman, Guus G, Schou, Rico Frederik, Sir, Özcan, Skandsen, Toril, Smeets, Dirk, Sorinola, Abayomi, Stamatakis, Emmanuel, Stevanovic, Ana, Stevens, Robert D, Sundström, Nina, Taccone, Fabio Silvio, Takala, Riikka, Tanskanen, Päivi, Taylor, Mark Steven, Telgmann, Ralph, Temkin, Nancy, Teodorani, Guido, Thomas, Matt, Tolias, Christos M, Trapani, Tony, Turgeon, Alexis, Vajkoczy, Peter, Valadka, Alex B, Valeinis, Egils, Vallance, Shirley, Vámos, Zoltán, Vargiolu, Alessia, Vega, Emmanuel, Verheyden, Jan, Vik, Anne, Vilcinis, Rimantas, Vleggeert-Lankamp, Carmen, Vogt, Lidia, Volovici, Victor, Voormolen, Daphne C, Vulekovic, Peter, Vande Vyvere, Thijs, Van Waesberghe, Julia, Wessels, Lars, Wildschut, Eno, Williams, Guy, Winkler, Maren K L, Wolf, Stefan, Wood, Gordon, Xirouchaki, Nektaria, Younsi, Alexander, Zaaroor, Menashe, Zelinkova, Veronika, Zemek, Roger, Zumbo, Fabrizio, Maas, Andrew I R, Menon, David K, Adelson, P David, Andelic, Nada, Bell, Michael J, Belli, Antonio, Bragge, Peter, Brazinova, Alexandra, Büki, András, Chesnut, Randall M, Citerio, Giuseppe, Coburn, Mark, Cooper, D Jamie, Crowder, A Tamara, Czeiter, Endre, Czosnyka, Marek, Diaz-Arrastia, Ramon, Dreier, Jens P, Duhaime, Ann-Christine, Ercole, Ari, van Essen, Thomas A, Feigin, Valery L, Gao, Guoyi, Giacino, Joseph, Gonzalez-Lara, Laura E, Gruen, Russell L, Gupta, Deepak, Hartings, Jed A, Hill, Sean, Jiang, Ji-yao, Ketharanathan, Naomi, Kompanje, Erwin J O, Lanyon, Linda, Laureys, Steven, Lecky, Fiona, Levin, Harvey, Lingsma, Hester F, Maegele, Marc, Majdan, Marek, Manley, Geoffrey, Marsteller, Jill, Mascia, Luciana, McFadyen, Charles, Mondello, Stefania, Newcombe, Virginia, Palotie, Aarno, Parizel, Paul M, Peul, Wilco, Piercy, James, Polinder, Suzanne, Puybasset, Louis, Rasmussen, Todd E, Rossaint, Rolf, Smielewski, Peter, Söderberg, Jeannette, Stanworth, Simon J, Stein, Murray B, von Steinbüchel, Nicole, Stewart, William, Steyerberg, Ewout W, Stocchetti, Nino, Synnot, Anneliese, Te Ao, Braden, Tenovuo, Olli, Theadom, Alice, Tibboel, Dick, Videtta, Walter, Wang, Kevin K W, Williams, W Huw, Wilson, Lindsay, and Yaffe, Kristine more...
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- 2017
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18. Metric learning for Parkinsonian identification from IMU gait measurements
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Cuzzolin, Fabio, Sapienza, Michael, Esser, Patrick, Saha, Suman, Franssen, Miss Marloes, Collett, Johnny, and Dawes, Helen
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- 2017
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19. The effect of breaking sitting time with physical activity breaks on cognitive performance in young people with cerebral palsy: an exposure response cross-over feasibility design.
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Coe, Shelly, Cossington, Jo, Collett, Johnny, Meaney, Andy, Mavrommati, Foteini, Ng, Yujun, Izadi, Hooshang, Wade, Will, Pindus, Dominika M., Bushnell, Oliver, Whaymand, Luke, Theologis, Tim, Swift, Emily, Akgul, Ece, Allen, Sam, and Dawes, Helen more...
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PHYSICAL activity ,COGNITIVE ability ,PEOPLE with cerebral palsy ,YOUNG adults ,SEDENTARY behavior - Abstract
To assess the feasibility of methods and estimate the potential effect of interrupting sedentary behaviour, with intermittent or continuous physical activity breaks, on cognitive performance in young people with Cerebral Palsy. A randomised three-arm exposure response cross-over design with process evaluation. Participants were recruited throughout the Thames Valley, UK between 01/11/2018 to 31/03/2020. The three 2 h activity exposure visits included: (i) sitting only (controls), (ii) sitting plus 20 min of moderate-to-vigorous activity burst, or (iii) 4×5 min of moderate-to-vigorous activity bursts, during a 2.5 h sedentary session. Measures of feasibility were sought. Cognitive performance outcomes (using the Eriksen Flanker task and Forward and Backward Digit Span) were delivered before and after the 2 h testing period. 36 participants were randomised (age 13.2±2.7, Gross-Motor Functional Classification System 1–3). Study retention was 83 % across all three interventions and overall missing data for measures was 4 %. A small intervention effect was found in reaction time in the 4×5 min physical activity exposure session compared to the sedentary control condition (0.42; 95 % CI 0.40 to 0.79). There were two research-related minor adverse effects, an allergic reaction to the FreeStyle Libre and feeling faint and vomiting after consumption of glucose solution. Both events were resolved and participants continued with the study. The study design and intervention implementing short bursts of physical activity was feasible and indicated a potential effect on reaction time as a measure of cognitive performance in young people with cerebral palsy. [ABSTRACT FROM AUTHOR] more...
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- 2024
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20. Use of the Capability, Opportunity and Motivation Behaviour model (COM-B) to Understand Interventions to Support Physical Activity Behaviour in People with Stroke: An Overview of Reviews.
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Paterson, Sarah, Dawes, Helen, Winward, Charlotte, Bartram, Emilia, Dodds, Emma, McKinon, Jane, Gaskell, Helen, and Collett, Johnny
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CINAHL database ,MEDICAL databases ,PSYCHOLOGY information storage & retrieval systems ,SOCIAL support ,MOTIVATION (Psychology) ,SYSTEMATIC reviews ,PHYSICAL therapy ,PSYCHOLOGY ,SPORTS ,BEHAVIOR ,PHYSICAL activity ,PSYCHOSOCIAL factors ,STROKE patients ,HEALTH behavior ,CONCEPTUAL models ,STROKE rehabilitation ,DECISION making in clinical medicine ,MEDLINE ,INFORMATION storage & retrieval systems ,PATIENT education ,HEALTH promotion ,EDUCATIONAL outcomes - Abstract
Objective: Physical activity in people with stroke remains low despite considerable research. This overview aimed to provide high-level synthesis and aid clinical decision-making. The Capability, Opportunity, Motivation-Behaviour (COM-B) model was used to classify interventions to understand which components improve physical activity behaviour in people with stroke. Data Sources: CINAHL, Cochrane Database, MEDLINE, PEDro, PsychINFO, SPORTDiscus Review Methods: A systematic search was conducted (November 2023) to identify reviews of interventions to improve physical activity in people with stroke. Results were screened and assessed for eligibility. Participant characteristics, intervention classification using COM-B, and effect of intervention were extracted. Quality was assessed using AMSTAR2, and Corrected Cover Analysis for study overlap. Narrative synthesis was used to understand components of interventions to improve physical activity behaviour. Results: 1801 references were screened and 29 full-text references assessed for eligibility. Twenty reviews were included. Quality ranged from critically low (n = 3) to high (n = 10). Study overlap calculated using corrected cover area indicated slight overlap (0.028) and minimal reporting bias. The majority of participants were mobile with mild stroke and community dwelling. Twenty-three interventions were classified using COM-B. Three of twelve interventions classified to one aspect of the COM-B were effective. Fourteen of sixteen effective interventions combined at least two COM-B elements, ten of these combined capability and motivation. Conclusion: Interventions including at least two elements of the COM-B are most likely to improve physical activity in mobile stroke survivors. Further research is needed to understand physical activity behaviour in those with moderate to severe stroke. [ABSTRACT FROM AUTHOR] more...
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- 2024
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21. A programme evaluation of 'First Steps': A peer-conceived, developed and led self-management intervention for people after a Parkinson's diagnosis.
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Collett, Johnny, Lawrie, Sophie, Bromley, Sally, Harling, Peter, Reed, Alex, Brusco, Natasha, Coe, Shelly, Coebergh, Jan, Carroll, Camille, Roberts, Helen C, Hu, Michele T, and Dawes, Helen
- Subjects
- *
AFFINITY groups , *SERVICES for caregivers , *PILOT projects , *EVALUATION of human services programs , *SOCIAL support , *CONFIDENCE intervals , *ACADEMIC medical centers , *SELF-management (Psychology) , *ACTIVITIES of daily living , *BURDEN of care , *MANN Whitney U Test , *HUMAN services programs , *PHYSICAL activity , *MEDICAL care use , *SELF-efficacy , *PRE-tests & post-tests , *PARKINSON'S disease , *COMMUNITY-based social services , *MENTAL depression , *QUALITY of life , *DESCRIPTIVE statistics , *QUESTIONNAIRES , *CHI-squared test , *RESEARCH funding , *ANXIETY , *ODDS ratio , *STATISTICAL sampling , *DATA analysis software - Abstract
Objective: A diagnosis of Parkinson's often leads to uncertainty about the future and loss of perceived control. Peer support may offer a means to address these concerns and promote self-management. Design: A programme evaluation of the feasibility and potential effects of 'First Steps', utilising a pragmatic step wedge approach. Comparing First Steps (intervention) to (control) conditions. Setting: In the community at four sites in southern England. Participants: Newly diagnosed (≤ 12months) people with Parkinson's. Intervention: First Steps was a 2-day peer-conceived, developed and led intervention to support self-management. Main measures: At 0, 12 and 24 weeks anxiety and depression (Hospital, Anxiety and Depression Scale, HADS), daily functioning (World Health Organisation Disability Assessment Schedule, WHODAS), physical activity, quality of life (EQ5D), carer strain and service utilisation were assessed. Results: Between February 2018 and July 2019, 36 participants were enrolled into intervention and 21 to control conditions, all were included in statistical analysis. Lost to follow up was n = 1 (intervention) and n = 1 adverse event was reported (control, unrelated). Of the 36 allocated to the intervention n = 22 participants completed both days of First Steps during the study period. Completion of outcome measures was >95% at 24 weeks. Small effects favouring the intervention were found for HADS (odds ratio (OR) = 2.06, 95% confidence interval (CI) 0.24:17.84), Carer Strain Index (OR = 2.22, 95% CI 0.5:9.76) and vigorous (d = 0.42, 95% CI −0.12:0.97) and total physical activity (d = 0.41, 95% CI −0.13:0.95). EQ5D, WHOSDAS and service utilisation, was similar between groups. Conclusions: First Steps was feasible and safe and we found potential to benefit physical activity, mental health and carer strain. Further research with longer-term follow up is warranted. [ABSTRACT FROM AUTHOR] more...
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- 2024
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22. Untersuchung von Hemm- und Förderfaktoren für das Ehrenamt als Intervention für Menschen mit neurologischer chronischer Erkrankung. Wie kann man therapeutisches Ehrenamt möglich machen?
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Eisenhut, Helene, Collett, Johnny, and Yazdani, Farzaneh
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VOLUNTEER service , *THERAPEUTICS , *FOCUS groups , *DISEASE management , *NEUROLOGICAL disorders , *CHRONIC diseases , *SOUND recordings , *THEMATIC analysis , *DATA analysis software , *WELL-being - Abstract
Introduction: Volunteering may have therapeutic benefits, but little is known about its requirements and potential for people with neurological conditions. Methods: Two separate focus groups were conducted in Darmstadt, Germany, one consisting of six people with neurological conditions and the second consisting of four healthcare professionals and three volunteering service providers. The focus groups were audio-recorded, transcribed, and data were managed using NVivo12. The thematic analysis was applied. Results: Four main themes were identified: 1. Impact of volunteering, 2. Individualisation, 3. Developmental space, and 4. Funded supported volunteering. Conclusion: According to the findings, volunteering can be used as a strategy to enhance physical, mental, and social well-being in disease management for people with long-term neurological conditions. [ABSTRACT FROM AUTHOR] more...
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- 2024
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23. High-intensity exhaustive exercise reduces long-interval intracortical inhibition
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O’Leary, Thomas J., Collett, Johnny, and Morris, Martyn G.
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- 2018
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24. Physical activity levels in adults with intellectual disabilities: A systematic review
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Dairo, Yetunde Marion, Collett, Johnny, Dawes, Helen, and Oskrochi, G. Reza
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- 2016
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25. A randomized, controlled trial of a multi-modal exercise intervention in Huntington’s disease
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Quinn, Lori, Hamana, Katy, Kelson, Mark, Dawes, Helen, Collett, Johnny, Townson, Julia, Roos, Raymund, van der Plas, Anton Adriaan, Reilmann, Ralf, Frich, Jan C., Rickards, Hugh, Rosser, Anne, and Busse, Monica more...
- Published
- 2016
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26. Exploring the barriers and facilitators to volunteering as an intervention for those with long‐term neurological conditions: How make therapeutic volunteering possible?
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Eisenhut, Helene, Collett, Johnny, and Yazdani, Farzaneh
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THERAPEUTICS , *WELL-being , *STATISTICS , *NEUROLOGICAL disorders , *FOCUS groups , *CHRONIC diseases , *VIDEOCONFERENCING , *QUALITATIVE research , *COMPARATIVE studies , *SELF-efficacy , *SOUND recordings , *CHI-squared test , *THEMATIC analysis , *DATA analysis software , *DATA analysis , *VOLUNTEER service , *DISEASE management - Abstract
Background: Volunteering may have therapeutic benefits, but little is known about its requirements and potential for people with neurological conditions (pwNC). Design: Two separate focus groups were conducted in Darmstadt, Germany: one group consisting of six pwNC and another group consisting of four health care professionals and three volunteering service providers. The focus groups were audio‐recorded, transcribed and data were managed using NVivo12. The thematic analysis was applied. Results: Four main themes were identified: (1) Impact of volunteering, (2) Individualisation, (3) Developmental space and (4) Funded supported volunteering. Conclusion: According to the findings, volunteering can be used as a strategy to enhance physical, mental and social well‐being in disease management for people with long‐term neurological conditions. Patients or Public Contribution: Facilitators for accessibility of therapeutic volunteering; involvement of pwNC. [ABSTRACT FROM AUTHOR] more...
- Published
- 2024
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27. High but not moderate-intensity endurance training increases pain tolerance: a randomised trial
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O’Leary, Thomas J., Collett, Johnny, Howells, Ken, and Morris, Martyn G.
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- 2017
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28. Insights into gait disorders: Walking variability using phase plot analysis, Huntington's disease
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Collett, Johnny, Esser, Patrick, Khalil, Hanan, Busse, Monica, Quinn, Lori, DeBono, Katy, Rosser, Anne, Nemeth, Andrea H., and Dawes, Helen
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- 2014
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29. Exploring the usability of a smartphone application to monitor fatigue and activity for people with acquired brain injury.
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Ezekiel, Leisle, Veiga, Jose Juan Dominguez, Ward, Tomas, Dawes, Helen, and Collett, Johnny
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USER-centered system design ,STATISTICS ,MOBILE apps ,SELF-management (Psychology) ,SELF-evaluation ,SMARTPHONES ,ACTIVITIES of daily living ,INTERVIEWING ,PHYSICAL activity ,EXPERIENCE ,SURVEYS ,QUALITATIVE research ,STROKE patients ,QUESTIONNAIRES ,FATIGUE (Physiology) ,BRAIN injuries ,CONTENT analysis ,TELEMEDICINE - Abstract
Background: Fatigue after acquired brain injury (ABI) leads to detrimental changes in ABI survivors' daily activities and participation. There is a need to capture individual's experience of fatigue as it happens, to better support self-management of fatigue. Study aims: To investigate the usability of a real-time tracker of fatigue and activity (using ecological momentary assessment delivered by a smartphone application) and the feasibility of capturing activity and environmental factors using phone sensors. Methods: Participants wore an activity monitor and completed up to eight surveys a day on a smartphone app, for 6 days, completed the system usability scale (SUS) and were interviewed on their views of using the app. Interview transcripts were analysed using qualitative content analysis. Agreement between data from the phone's sensors and the activity monitor was analysed using Kappa statistics. Results: Seven participants completed between 11 and 58 surveys. Mean score on the SUS indicated good perceived usability of the app. Phone sensors did not reliably capture physical activity or background noise. Participants found the app easy to use and perceived self-monitoring to help their understanding of fatigue. A fatigue-tracking app may be acceptable to ABI survivors and has potential to aid self-management of fatigue. [ABSTRACT FROM AUTHOR] more...
- Published
- 2023
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30. Insights into gait disorders: Walking variability using phase plot analysis, Parkinson's disease
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Esser, Patrick, Dawes, Helen, Collett, Johnny, and Howells, Ken
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- 2013
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31. A long-term self-managed handwriting intervention for people with Parkinson’s disease: results from the control group of a phase II randomized controlled trial
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Collett, Johnny, Franssen, Marloes, Winward, Charlotte, Izadi, Hooshang, Meaney, Andy, Mahmoud, Wala, Bogdanovic, Marko, Tims, Martin, Wade, Derick, and Dawes, Helen
- Published
- 2017
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32. Motor learning in developmental coordination disorder: behavioral and neuroimaging study.
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Al-Yahya, Emad, Esser, Patrick, Weedon, Benjamin D., Joshi, Shawn, Yan-Ci Liu, Springett, Daniella N., Salvan, Piergiorgio, Meaney, Andy, Collett, Johnny, Inacio, Mario, Delextrat, Anne, Kemp, Steve, Ward, Tomas, Izadi, Hooshang, Johansen-Berg, Heidi, Ayaz, Hasan, and Dawes, Helen more...
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APRAXIA ,MOTOR learning ,FUNCTIONAL magnetic resonance imaging ,MOTOR ability ,PHYSICAL fitness ,STIMULUS & response (Psychology) - Abstract
Developmental coordination disorder (DCD) is characterized by motor learning deficits that are poorly understood within whole-body activities context. Here we present results of one of the largest non-randomized interventional trials combining brain imaging and motion capture techniques to examine motor skill acquisition and its underpinning mechanisms in adolescents with and without DCD. A total of 86 adolescents with low fitness levels (including 48 with DCD) were trained on a novel stepping task for a duration of 7 weeks. Motor performance during the stepping task was assessed under single and dualtask conditions. Concurrent cortical activation in the prefrontal cortex (PFC) was measured using functional near-infrared spectroscopy (fNIRS). Additionally, structural and functional magnetic resonance imaging (MRI) was conducted during a similar stepping task at the beginning of the trial. The results indicate that adolescents with DCD performed similarly to their peers with lower levels of fitness in the novel stepping task and demonstrated the ability to learn and improve motor performance. Both groups showed significant improvements in both tasks and under single- and dual-task conditions at post-intervention and follow-up compared to baseline. While both groups initially made more errors in the Stroop task under dual-task conditions, at follow-up, a significant difference between single- and dual-task conditions was observed only in the DCD group. Notably, differences in prefrontal activation patterns between the groups emerged at different time points and task conditions. Adolescents with DCD exhibited distinct prefrontal activation responses during the learning and performance of a motor task, particularly when complexity was increased by concurrent cognitive tasks. Furthermore, a relationship was observed between MRI brain structure and function measures and initial performance in the novel stepping task. Overall, these findings suggest that strategies that address task and environmental complexities, while simultaneously enhancing brain activity through a range of tasks, offer opportunities to increase the participation of adolescents with low fitness in physical activity and sports. [ABSTRACT FROM AUTHOR] more...
- Published
- 2023
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33. Understanding hope in patients with Multiple Sclerosis
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Soundy, Andy, Benson, James, Dawes, Helen, Smith, Brett, Collett, Johnny, and Meaney, Andy
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- 2012
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34. Validity and inter-rater reliability of inertial gait measurements in Parkinson's disease: A pilot study
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Esser, Patrick, Dawes, Helen, Collett, Johnny, Feltham, Max G., and Howells, Ken
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- 2012
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35. Lost employment potential and supporting people with Parkinson's to stay in work: insights from a Pan European cross-sectional survey.
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Collett, Johnny, Brusco, Natasha, Cordell, Nikki, Cockroft, Annette, Lawrie, Sophie, Coe, Shelly, Reed, Alex, and Dawes, Helen
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- *
UNEMPLOYMENT , *CONFIDENCE intervals , *CROSS-sectional method , *JOB stress , *VISUAL analog scale , *REGRESSION analysis , *HEALTH status indicators , *COST benefit analysis , *COMPARATIVE studies , *PARKINSON'S disease , *EMPLOYMENT , *DESCRIPTIVE statistics , *KAPLAN-Meier estimator , *QUALITY of life , *QUESTIONNAIRES , *CHI-squared test , *SOCIODEMOGRAPHIC factors , *ECONOMIC aspects of diseases , *DATA analysis software , *STATISTICAL sampling - Abstract
To explore, in a European cohort of people living with Parkinson's (PD), issues affecting employment and economic consequences, considering age at diagnosis. A cross-sectional survey (European convenience sample). Inclusion criteria were ≥18 years, a PD diagnosis and in work when diagnosed. Data were collected online on demographics, employment status, occupation, and perceived health. For those no longer in paid work, time from diagnosis until loss of employment, reasons for leaving and enablers to stay in work were ascertained. Between April and November 2019, n = 692 enrolled and n = 560 were eligible. Those who had lost paid work (n = 190, 34%) reported worse fatigue, sleep, and general health than those still in work (p < 0.05). Average annual income reduced from €26973.48 ± 12013.22 (year-1) to €14843.85 ± 16969.84 (year-10). Post-diagnosis lost employment potential was 20.1 (95% confidence interval (CI): 16.6–23.6) years at career establishment, 9.8 (95%CI: 8.9–10.7) years at mid working and 1.2 (95%CI: 0.6–1.6) years for those nearing retirement age. A greater proportion of individuals at career establishment age reported dexterity, eating, sleep, fatigue, and anxiety as factors for leaving work (p < 0.05). This study confirms lost productivity after a PD diagnosis, especially in those with many years of potential employment ahead. The study also identified potential targets for interventions. Clinical trial registration: Clincaltrials.gov (NCT03905954). People with Parkinson's diagnosed at career establishment or at mid working age risk losing many years of potential employment. Most people with Parkinson's do not receive early intervention to support self-management of problems identified with leaving work early, such as fatigue. Adaptations to the work environment and more flexible working patterns were identified factors that may help people remain in work. [ABSTRACT FROM AUTHOR] more...
- Published
- 2023
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36. Fast walking under cognitive-motor interference conditions in chronic stroke
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Dennis, Andrea, Dawes, Helen, Elsworth, Charlotte, Collett, Johnny, Howells, Ken, Wade, Derick T., Izadi, Hooshang, and Cockburn, Janet
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- 2009
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37. Interventions for fatigue in Parkinsonʼs disease: A systematic review and meta-analysis
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Franssen, Marloes, Winward, Charlotte, Collett, Johnny, Wade, Derick, and Dawes, Helen
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- 2014
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38. Pedometer step counts in individuals with neurological conditions
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Elsworth, Charlotte, Dawes, Helen, Winward, Charlotte, Howells, Ken, Collett, Johnny, Dennis, Andrea, Sackley, Catherine, and Wade, Derick
- Published
- 2009
39. RETAIN Kentucky: A return-to-work and stay-at-work program for people with disabilities grounded in the conservation of resources theory.
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Rumrill, Phillip, Sheppard-Jones, Kathy, Collett, Johnny W., and McCurry, Sara
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PILOT projects ,UNIVERSAL design ,SOCIAL determinants of health ,EMPLOYEE assistance programs ,CONCEPTUAL structures ,LABOR supply ,SOCIAL security ,QUALITY of life ,EMPLOYMENT ,EMPLOYMENT reentry ,PEOPLE with disabilities ,CONCEPTS - Abstract
This article, the first in the Return-to-Work (RTW) Corner series, summarizes a comprehensive RTW and Stay-at-Work (SAW) program in Kentucky, which is funded by the United States Department of Labor. The program, Retaining Employment and Talent After Injury/Illness Network: Kentucky (RETAIN Kentucky), focuses on RTW and SAW strategies, depending upon participants' employment status at the time of enrollment in the project. RETAIN Kentucky services are implemented by RTW Coordinators (RTWCs) who help people with non-work-related injuries and illnesses continue in the workforce. The first Phase of RETAIN Kentucky, which lasted for nearly 3 years, is now informing the Phase 2 intervention, which began in October 2021 and will enroll participants for 30 months. In this article, we outline the employment retention problem that RETAIN Kentucky addresses, describe the key features and services of the program, summarize our findings so far, and present future directions for Phase 2. [ABSTRACT FROM AUTHOR] more...
- Published
- 2022
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40. Declining fitness and physical education lessons in UK adolescents.
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Weedon, Benjamin David, Liu, Francesca, Mahmoud, Wala, Burden, Samuel Joseph, Whaymand, Luke, Esser, Patrick, Collett, Johnny, Izadi, Hooshang, Joshi, Shawn, Meaney, Andy, Delextrat, Anne, Kemp, Steve, Jones, Alexander, and Dawes, Helen more...
- Published
- 2022
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41. Dual-task walking and automaticity after Stroke: Insights from a secondary analysis and imaging sub-study of a randomised controlled trial.
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Collett, Johnny, Fleming, Melanie K, Meester, Daan, Al-Yahya, Emad, Wade, Derick T, Dennis, Andrea, Salvan, Piergiorgio, Meaney, Andrew, Cockburn, Janet, Dawes, Joanna, Johansen-Berg, Heidi, and Dawes, Helen more...
- Subjects
- *
WALKING speed , *EXECUTIVE function , *EXERCISE tests , *CONFIDENCE intervals , *GAIT in humans , *TASK performance , *TREADMILLS , *MAGNETIC resonance imaging , *MANN Whitney U Test , *RANDOMIZED controlled trials , *COMPARATIVE studies , *T-test (Statistics) , *WALKING , *STROKE patients , *RESOURCE allocation , *BLIND experiment , *CHI-squared test , *RESEARCH funding , *DATA analysis software , *STATISTICAL correlation , *ODDS ratio , *BARTHEL Index , *SECONDARY analysis - Abstract
Objective: To test the extent to which initial walking speed influences dual-task performance after walking intervention, hypothesising that slow walking speed affects automatic gait control, limiting executive resource availability. Design: A secondary analysis of a trial of dual-task (DT) and single-task (ST) walking interventions comparing those with good (walking speed ⩾0.8 m s−1, n = 21) and limited (walking speed <0.79 m s−1, n = 24) capacity at baseline. Setting: Community. Subjects: Adults six-months post stroke with walking impairment. Interventions: Twenty sessions of 30 minutes treadmill walking over 10 weeks with (DT) or without (ST) cognitive distraction. Good and limited groups were formed regardless of intervention received. Main measures: A two-minute walk with (DT) and without (ST) a cognitive distraction assessed walking. f NIRS measured prefrontal cortex activation during treadmill walking with (DT) and without (ST) Stroop and planning tasks and an f MRI sub-study used ankle-dorsiflexion to simulate walking. Results: ST walking improved in both groups (∆baseline: Good = 8.9 ± 13.4 m, limited = 5.3±8.9 m, Group × time = P < 0.151) but only the good walkers improved DT walking (∆baseline: Good = 10.4 ± 13.9 m, limited = 1.3 ± 7.7 m, Group × time = P < 0.025). f NIRS indicated increased ispilesional prefrontal cortex activation during DT walking following intervention (P = 0.021). f MRI revealed greater DT cost activation for limited walkers, and increased resting state connectivity of contralesional M1 with cortical areas associated with conscious gait control at baseline. After the intervention, resting state connectivity between ipsilesional M1 and bilateral superior parietal lobe, involved in integrating sensory and motor signals, increased in the good walkers compared with limited walkers. Conclusion: In individual who walk slowly it may be difficult to improve dual-task walking ability. Registration: ISRCTN50586966 [ABSTRACT FROM AUTHOR] more...
- Published
- 2021
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42. Dual-Task Effect on Gait in Healthy Adolescents: Association between Health-Related Indicators and DT Performance.
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Cinar, Eda, Weedon, Benajmin David, Esser, Patrick, Joshi, Shawn, Liu, Yan-Ci, Delextrat, Anne, Meaney, Andy, Collett, Johnny, Springett, Daniella Nicole, and Dawes, Helen
- Subjects
GAIT in humans ,WALKING speed ,TEENAGE girls ,GENDER ,MULTIPLE regression analysis ,CHILDREN with cerebral palsy - Abstract
The purpose of this study was to determine how dual-task (DT) effect on gait differs among adolescents with different fitness and health profiles. The gait performances of 365 adolescents aged 13–14 years were assessed at single and DT walking. The proportional changes in gait parameters from single to dual were regressed against gender, body mass index (BMIz), three components of MABC-2 (balance, aiming &catching and manual dexterity), group (high vs low motor competence), body strength, physical fitness level using multiple regression analyses; and gender and four items of balance subtest of MABC-2 in the secondary analysis. The analyses showed that being female was associated with greater reduction in gait speed and stride length and an increase in double support time and step time; and having lower score in balance was related to greater reduction in gait speed, and cadence, and an increase in step time. Only zig-zag hopping item of the balance subtest was associated with DT effect on gait speed and stride length. No significant relationships were found between DT effect on gait and the rest of the predictors. Females and adolescents with lower level of balance function may be at higher risk of having DT deficit during walking. [ABSTRACT FROM AUTHOR] more...
- Published
- 2021
- Full Text
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43. Experiences of fatigue in daily life of people with acquired brain injury: a qualitative study.
- Author
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Ezekiel, Leisle, Field, Leanne, Collett, Johnny, Dawes, Helen, and Boulton, Mary
- Subjects
SOCIAL participation ,SOCIAL support ,RESEARCH methodology ,INTERVIEWING ,EXPERIENCE ,QUALITATIVE research ,QUALITY of life ,SUPPORT groups ,DESCRIPTIVE statistics ,QUESTIONNAIRES ,BRAIN injuries ,FATIGUE (Physiology) ,THEMATIC analysis ,PSYCHOLOGICAL adaptation ,MENTAL fatigue - Abstract
To develop an in-depth understanding of how survivors of acquired brain injury (ABI) experience fatigue and how fatigue affects everyday life. We conducted semi-structured in-depth interviews with 16 adults with ABI fatigue, recruited from support groups in south east UK. Interviews were analysed using the frameworks method. We developed four themes: experiencing fatigue in the context of everyday activities, struggling to make sense of fatigue, coping with fatigue, and adjusting social participation in the context of fatigue. Fatigue was comprised of mental, physical, generalised, and motivational fatigue. Balancing fatigue against participation in daily activities was influenced by coping strategies and social support. Opportunities to socialize or participate in meaningful activities provided incentives for participants to push through their fatigue. This study highlights complex interactions that potentially mitigate the impact of fatigue on everyday life. Educational and self-management approaches to fatigue need to account for different types of fatigue in the contexts of an individual's daily activity. Assessment of fatigue should capture in-the-moment experiences of different types of fatigue and activity. Social support and participation in meaningful activities may help individuals to break the negative cycle of fatigue and inactivity. Assessment of fatigue after brain injury should capture the multidimensional nature of fatigue as well as contextual information about exacerbating activities and environments. Development of personalised coping strategies that account for perceived triggers of different subtypes of fatigue may help ABI survivors to broaden their activity and social participation. Social support and opportunities to participate in personally meaningful activities may help prevent or break a negative cycle of fatigue and inactivity for some ABI survivors. [ABSTRACT FROM AUTHOR] more...
- Published
- 2021
- Full Text
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44. Task-Specific Training in Huntington Disease: A Randomized Controlled Feasibility Trial
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Quinn, Lori, Debono, Katy, Dawes, Helen, Rosser, Anne Elizabeth, Nemeth, Andrea H., Rickards, Hugh, Tabrizi, Sarah J., Quarrell, Oliver, Trender-Gerhard, Iris, Kelson, Mark J., Townson, Julia, Busse, Monica, Akhtar, Shabana, Crooks, Jennifer, De Souza, Jennifer, Gibson, Kerry, Jones, Claire, Johnston, Catherine, Jones, Karen, McLauchlan, Duncan, Allen, Joanna, Cosh, Rosie, Haider, Salman, Lewis, Monica, Robertson, Nicola, Rodger, Anne, Stokes, Rhiannon, Taylor, Rachel, Bek, Judith, Rogers, Dawn, Stopford, Cheryl, Teal, Jo, Collett, Johnny, Davies, Loretta, Sheridan, Bryony, Barnes, Laura, Crossland, Kay, Cruise, Rachel, Ingram, Stuart, Jones, Natalie, Sandhu, Molly, and Taylor, Cat more...
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Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Medizin ,MEDLINE ,Physical Therapy, Sports Therapy and Rehabilitation ,Motor Activity ,Goal Attainment Scaling ,law.invention ,Physical medicine and rehabilitation ,Randomized controlled trial ,Rating scale ,law ,Intervention (counseling) ,Outcome Assessment, Health Care ,Task Performance and Analysis ,Health care ,Humans ,Medicine ,Adverse effect ,Aged ,Rehabilitation ,business.industry ,Recovery of Function ,Middle Aged ,Home Care Services ,Exercise Therapy ,Huntington Disease ,Physical therapy ,Feasibility Studies ,Patient Compliance ,Female ,business ,Goals ,Follow-Up Studies - Abstract
Background Task-specific training may be a suitable intervention to address mobility limitations in people with Huntington disease (HD). Objective The aim of this study was to assess the feasibility and safety of goal-directed, task-specific mobility training for individuals with mid-stage HD. Design This study was a randomized, blinded, feasibility trial; participants were randomly assigned to control (usual care) and intervention groups. Setting This multisite study was conducted in 6 sites in the United Kingdom. Patients Thirty individuals with mid-stage HD (13 men, 17 women; mean age=57.0 years, SD=10.1) were enrolled and randomly assigned to study groups. Intervention Task-specific training was conducted by physical therapists in participants' homes, focusing on walking, sit-to-stand transfers, and standing, twice a week for 8 weeks. Goal attainment scaling was used to individualize the intervention and monitor achievement of personal goals. Measurements Adherence and adverse events were recorded. Adjusted between-group comparisons on standardized outcome measures were conducted at 8 and 16 weeks to determine effect sizes. Results Loss to follow-up was minimal (n=2); adherence in the intervention group was excellent (96.9%). Ninety-two percent of goals were achieved at the end of the intervention; 46% of the participants achieved much better than expected outcomes. Effect sizes on all measures were small. Limitations Measurements of walking endurance were lacking. Conclusions The safety of and excellent adherence to a home-based, task-specific training program, in which most participants exceeded goal expectations, are encouraging given the range of motivational, behavioral, and mobility issues in people with HD. The design of the intervention in terms of frequency (dose), intensity (aerobic versus anaerobic), and specificity (focused training on individual tasks) may not have been sufficient to elicit any systematic effects. Thus, a larger-scale trial of this specific intervention does not seem warranted. more...
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- 2014
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45. Effect of Combined Therapy of Virtual Reality and Transcranial Direct Current Stimulation in Children and Adolescents With Cerebral Palsy: A Study Protocol for a Triple-Blinded Randomized Controlled Crossover Trial.
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Silva, Talita Dias da, Fontes, Anne Michelli Gomes Gonçalves, Oliveira-Furlan, Barbara Soares de, Roque, Tatiane Tedeschi, Lima, Ana Izabel Izidório, Souza, Bruna Mayara Magalhães de, Alberissi, Camila Aparecida de Oliveira, Silveira, Ana Clara, Moraes, Íbis Ariana Peña de, Collett, Johnny, Silva, Roger Pereira, Airoldi, Marina Junqueira, Ribeiro-Papa, Denise Cardoso, Dawes, Helen, and Monteiro, Carlos Bandeira de Mello more...
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TRANSCRANIAL direct current stimulation ,VIRTUAL reality therapy ,CHILDREN with cerebral palsy ,REALITY therapy ,CROSSOVER trials ,FUNCTIONAL assessment - Abstract
Background: Transcranial direct current stimulation (tDCS) and therapy-based virtual reality (VR) have been investigated separately. They have shown promise as efficient and engaging new tools in the neurological rehabilitation of individuals with cerebral palsy (CP). However, the recent literature encourages investigation of the combination of therapy tools in order to potentiate clinic effects and its mechanisms. Methods: A triple-blinded randomised sham-controlled crossover trial will be performed. Thirty-six individuals with gross motor function of levels I to IV (aged 4–14 years old) will be recruited. Individuals will be randomly assigned to Group A (active first) or S (sham first): Group A will start with ten sessions of active tDSC combined with VR tasks. After a 1-month washout, this group will be reallocated to another ten sessions with sham tDCS combined with VR tasks. In contrast, Group S will carry out the opposite protocol, starting with sham tDCS. For the active tDCS the protocol will use low frequency tDCS [intensity of 1 milliampere (mA)] over the primary cortex (M1) area on the dominant side of the brain. Clinical evaluations (reaction times and coincident timing through VR, functional scales: Abilhand-Kids, ACTIVLIM-CP, Paediatric Evaluation of Disability Inventory-PEDI- and heart rate variability-HRV) will be performed at baseline, during, and after active and sham tDCS. Conclusion: tDCS has produced positive results in treating individuals with CP; thus, its combination with new technologies shows promise as a potential mechanism for improving neurological functioning. The results of this study may provide new insights into motor rehabilitation, thereby contributing to the better use of combined tDCS and VR in people with CP. Trial Registration: ClinicalTrials.gov, NCT04044677. Registered on 05 August 2019. [ABSTRACT FROM AUTHOR] more...
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- 2020
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46. A randomised double-blind placebo-controlled feasibility trial of flavonoid-rich cocoa for fatigue in people with relapsing and remitting multiple sclerosis.
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Coe, Shelly, Cossington, Jo, Collett, Johnny, Soundy, Andrew, Izadi, Hooshang, Ovington, Martin, Durkin, Luke, Kirsten, Maja, Clegg, Miriam, Cavey, Ana, Wade, Derick T., Palace, Jacqueline, DeLuca, Gabriele C., Chapman, Kim, Harrison, Jane-Marie, Buckingham, Elizabeth, and Dawes, Helen more...
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MULTIPLE sclerosis ,FATIGUE (Physiology) ,NEUROREHABILITATION ,COCOA ,SOCIAL sciences - Abstract
The impact of flavonoids on fatigue has not been investigated in relapsing and remitting multiple sclerosis (RRMS).
Objective: To determine the feasibility and estimate the potential effect of flavonoid-rich cocoa on fatigue and fatigability in RRMS.Methods: A randomised double-blind placebo-controlled feasibility study in people recently diagnosed with RRMS and fatigue, throughout the Thames Valley, UK (ISRCTN69897291). During a 6-week intervention participants consumed a high or low flavonoid cocoa beverage daily. Fatigue and fatigability were measured at three visits (weeks 0, 3 and 6). Feasibility and fidelity were assessed through recruitment and retention, adherence and a process evaluation.Results: 40 people with multiple sclerosis (10 men, 30 women, age 44±10 years) were randomised and allocated to high (n=19) or low (n=21) flavonoid groups and included in analysis. Missing data were <20% and adherence to intervention of allocated individuals was >75%. There was a small effect on fatigue (Neuro-QoL: effect size (ES) 0.04, 95% CI -0.40 to 0.48) and a moderate effect on fatigability (6 min walk test: ES 0.45, 95% CI -0.18 to 1.07). There were seven adverse events (four control, three intervention), only one of which was possibly related and it was resolved.Conclusion: A flavonoid beverage demonstrates the potential to improve fatigue and fatigability in RRMS. [ABSTRACT FROM AUTHOR] more...- Published
- 2019
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47. Single Sensor Gait Analysis to Detect Diabetic Peripheral Neuropathy: A Proof of Principle Study.
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Esser, Patrick, Collett, Johnny, Maynard, Kevin, Steins, Dax, Hillier, Angela, Buckingham, Jodie, Tan, Garry D., King, Laurie, and Dawes, Helen
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GAIT in humans , *DIAGNOSIS of diabetic neuropathies ,PREVENTION of diabetes complications - Abstract
This study explored the potential utility of gait analysis using a single sensor unit (inertial measurement unit [IMU]) as a simple tool to detect peripheral neuropathy in people with diabetes. Seventeen people (14 men) aged 63±9 years (mean±SD) with diabetic peripheral neuropathy performed a 10-m walk test instrumented with an IMU on the lower back. Compared to a reference healthy control data set (matched by gender, age, and body mass index) both spatiotemporal and gait control variables were different between groups, with walking speed, step time, and SDa (gait control parameter) demonstrating good discriminatory power (receiver operating characteristic area under the curve >0.8). These results provide a proof of principle of this relatively simple approach which, when applied in clinical practice, can detect a signal from those with known diabetes peripheral neuropathy. The technology has the potential to be used both routinely in the clinic and for tele-health applications. Further research should focus on investigating its efficacy as an early indicator of or effectiveness of the management of peripheral neuropathy. This could support the development of interventions to prevent complications such as foot ulceration or Charcot's foot. [ABSTRACT FROM AUTHOR] more...
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- 2018
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48. Exercise response in Parkinson’s disease: insights from a cross-sectional comparison with sedentary controls and a per-protocol analysis of a randomised controlled trial.
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Mavrommati, Foteini, Collett, Johnny, Franssen, Marloes, Meaney, Andy, Sexton, Claire, Dennis-West, Andrea, Betts, Jill F., Izadi, Hooshang, Bogdanovic, Marko, Tims, Martin, Farmer, Andrew, and Dawes, Helen more...
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Objectives: To investigate the acute and adaptation cardiovascular and metabolic training responses in people with Parkinson’s disease (pwP). Design: (1) A cross-sectional study of exercise response of pwP compared with sedentary controls and (2) an interventional study of exercise training in pwP. Setting: Community leisure facilities. Participants: pwP (n=83) and sedentary controls (n=55). Interventions; Study 1 included participants from a twoarm- parallel single-blind phase II randomised controlled trial (RCT), that undertook a baseline maximal incremental exercise test and study 2 included those randomised to the exercise group in the RCT, who completed a 6-month weekly exercise programme (n=37). The intervention study 2 was a prescribed exercise program consisting of sessions lasting 60 min, two times a week over a 6-month period. The control group followed the same protocol which derived the same cardiorespiratory parameters, except that they were instructed to aim for a cadence of ~60 revolutions per minute and the unloaded phase lasted 3 min with an initial step of 25 W. Primary and secondary outcome measures: Stepwise incremental exercise test to volitional exhaustion was the primary outcome measure. Results: Study 1 showed higher maximum values for heart rate (HR), VO
2 L/min, VCO2 L/min and ventilation L/ min for the control group; respiratory exchange ratio (RER), perceived exertion and O2 pulse (VO2 L/min/HR) did not differ between groups. In study 2, for pwP who adhered to training (n=37), RER increased significantly and although there was no significant change in aerobic capacity or HR response, reduced blood pressure was found. Conclusions: An abnormal cardiovascular response to exercise was observed in pwP compared to controls. After the exercise programme, metabolic deficiencies remained for pwP. These observations add to the pathogenic understanding of PD, acknowledge an underling metabolic contribution and support that certain cardiovascular symptoms may improve as a result of this type of exercise. [ABSTRACT FROM AUTHOR] more...- Published
- 2017
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49. High but not moderate-intensity endurance training increases pain tolerance: a randomised trial.
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O'Leary, Thomas, Collett, Johnny, Howells, Ken, Morris, Martyn, O'Leary, Thomas J, and Morris, Martyn G
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AEROBIC exercises ,TREADMILL exercise ,INTERVAL training ,EXERCISE intensity ,LACTATES ,COMPARATIVE studies ,RESEARCH methodology ,MEDICAL cooperation ,MYALGIA ,RESEARCH ,STATISTICAL sampling ,EVALUATION research ,RANDOMIZED controlled trials ,OXYGEN consumption ,EXERCISE tolerance ,MUSCLE fatigue ,PAIN threshold ,PREVENTION - Abstract
Purpose: To examine the effect of high-intensity interval training (HIIT) compared to volume-matched moderate-intensity continuous training (CONT) on muscle pain tolerance and high-intensity exercise tolerance.Methods: Twenty healthy adults were randomly assigned (1:1) to either 6 weeks of HIIT [6-8 × 5 min at halfway between lactate threshold and maximal oxygen uptake (50%Δ)] or volume-matched CONT (~60-80 min at 90% lactate threshold) on a cycle ergometer. A tourniquet test to examine muscle pain tolerance and two time to exhaustion (TTE) trials at 50%Δ to examine exercise tolerance were completed pre- and post-training; the post-training TTE trials were completed at the pre-training 50%Δ (same absolute-intensity) and the post-training 50%Δ (same relative-intensity).Results: HIIT and CONT resulted in similar improvements in markers of aerobic fitness (all P ≥ 0.081). HIIT increased TTE at the same absolute- and relative-intensity as pre-training (148 and 43%, respectively) to a greater extent than CONT (38 and -4%, respectively) (both P ≤ 0.019). HIIT increased pain tolerance (41%, P < 0.001), whereas CONT had no effect (-3%, P = 0.720). Changes in pain tolerance demonstrated positive relationships with changes in TTE at the same absolute- (r = 0.44, P = 0.027) and relative-intensity (r = 0.51, P = 0.011) as pre-training.Conclusion: The repeated exposure to a high-intensity training stimulus increases muscle pain tolerance, which is independent of the improvements in aerobic fitness induced by endurance training, and may contribute to the increase in high-intensity exercise tolerance following HIIT. [ABSTRACT FROM AUTHOR] more...- Published
- 2017
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50. Acute recovery from exercise in people with multiple sclerosis: an exploratory study on the effect of exercise intensities.
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Collett, Johnny, Meaney, Andy, Howells, Ken, and Dawes, Helen
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MULTIPLE sclerosis , *COOLDOWN , *EXERCISE , *FATIGUE (Physiology) , *PEOPLE with disabilities , *PSYCHOLOGY , *PHYSIOLOGY , *PATIENTS , *ANALYSIS of variance , *STATISTICAL correlation , *CROSSOVER trials , *RESEARCH , *RESEARCH funding , *SCALE analysis (Psychology) , *T-test (Statistics) , *REPEATED measures design , *ERGOMETRY , *DATA analysis software , *DESCRIPTIVE statistics - Abstract
PurposeA better understanding of how people with multiple sclerosis (pwMS) recover from exercise may help inform interventions.MethodsWe explored physiological and perceptual responses following exercise of different intensities, using a crossover exposure-response design, in 14 adults with multiple sclerosis (MS) and 9 controls. A cycling exercise test determined maximum capacity (Wpeak). Participants then performed 20-min exercise sessions relative to Wpeak (random order separated by 7 days): (1) 45% and (2) 60% continuous cycling and (3) 90% intermittent cycling (30 s cycling, 30 s rest). During a 45-min recovery period, tympanic temperature (Temp°C), exertion in breathing (RPEbr) and legs (RPEleg), and cortical excitability (MEParea) were measured.ResultsEleven pwMS and eight controls completed the study. Controls performed better on the exercise test (p < 0.05), thus more absolute work during subsequent sessions. PwMS took longer to recover RPEleg with recovery time increasing with intensity (45%-6 min; 60%-15 min; 90%-35 min) and correlating with Temp°C. MEParea was significantly depressed in both groups at 45% and 60% (p < 0.001), in the MS group this also correlated with RPEleg.ConclusionsFeelings of leg exertion may persist after exercise in some pwMS, especially at high intensities. This may relate to body temperature and, after continuous exercise, cortical excitability. These results support considering the recovery period post exercise and provide an insight into potential correlates of post-exercise fatigue.Implications for RehabilitationA better understanding of how pwMS recover following exercise may help inform exercise prescription a long side fatigue management.This study showed that, in pwMS, the time taken to recover from feelings of leg fatigue increased with the intensity of the exercise session rather that total work performed and was related to increase in body temperature.The results of this relatively small study support the need to consider a recovery period after exercise and provide an insight into potential physiological correlates [ABSTRACT FROM PUBLISHER] more...
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- 2017
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