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Your search keyword '"D’Ovidio, C."' showing total 17 results
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17 results on '"D’Ovidio, C."'

9. First report of an acute purulent maxillary sinusitis caused by Pseudomonas aeruginosa secondary to dental implant placement in an immunocompetent patient.

Author

D'Ovidio, C., Carnevale, A., Pantaleone, G., Piattelli, A., and Di Bonaventura, G.

Subjects
*PSEUDOMONAS aeruginosa infections, *MAXILLARY sinus, *AUTOTRANSPLANTATION, *DENTAL implants
Abstract

Study design In this case report, we present maxillary Pseudomonas aeruginosa sinusitis in an immunocompetent patient who underwent an autologous bone transplant for the insertion of dental implants.Results The infection was eradicated after removal of the dental implants and long-term antibiotic therapy.Conclusion Despite the infection resolution, severe complications were observed with important legal consequences. [ABSTRACT FROM AUTHOR]

Published
2011
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15. Fast liquid chromatography-tandem mass spectrometry method for the simultaneous determination of phytocannabinoids in oily based preparations.

Author

Merone, G.M., Tartaglia, A., Rossi, S., Santavenere, F., Bassotti, E., D'Ovidio, C., Bonelli, M., Rosato, E., de Grazia, U., Zanardo, A., Locatelli, M., and Savini, F.

Subjects
*LIQUID chromatography-mass spectrometry, *MATRIX effect, *FORMIC acid, *CANNABINOIDS
Abstract

• Fast LC–MS/MS method for 7 phytocannabinoids in oily based formulations. • Quality control on magistrali preparations. • First method for oily based cannabis preparations QC. • Innovative configurations to maximize the instrumental performances. • Green Analytical Procedure Index (GAPI) evaluation. The reported method aims to be a powerful aid for the simultaneous determination of tetrahydrocannabinol (THC), cannabidiol (CBD), cannabinol (CBN), cannabigerol (CBG), tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and tetrahydrocannabivarin (THCV) in oily based preparations. The chromatographic separation was carried out using an Hypersil Gold PFP (50 × 2.1 mm, 1.9 μm) column, using H2O + 2 mM ammonium formate + 0.2 % formic acid (M1) and Methanol + 2 mM ammonium formate + 0.2 % formic acid (M2) as mobile phases. The flow rate was set 0.4 mL/min. Specifically, this method was validated in terms of linearity, limit of detections and quantifications (LODs and LOQs), accuracy (precision and trueness, both intra and interday), selectivity, and matrix effects. This procedure allowed quantifying seven phytocannabinoids in less than 10 min. The validated method shows a good linearity within the range 0.25−1000 ng/mL, while precision and trueness (intra- and inter-day) were below <13.25 % and 7.59 %, respectively. Regarding the matrix effect, the method satisfies all the requirements, except for the THC and THCV, where it reaches about 120 %. This element does not affect the method performances as it has been observed that this value is constant and reproducible and therefore does not involve errors in the quantitative analysis. The method was tested and applied on more 70 different oily based preparations. Furthermore, starting from four different cannabis cultivar (FM2, Bedrolite, Bedrocan, and Bediol), it allowed to evaluate the reproducibility of the magistrali preparations. The real samples, in fact, derive from different local pharmacies, and were analyzed by the accredited UNI CEI EN ISO/IEC 17025:2018, Pharmatoxicology Laboratory (ACCREDIA, lab n. 2274 ASLPE, accreditation number 1822 L), accordingly to the current regulations. [ABSTRACT FROM AUTHOR]

Published
2021
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16. Novel MIPs-Parabens based SPE Stationary Phases Characterization and Application

Author

Fabio Savini, Kenneth G. Furton, Ugo de Grazia, Angela Tartaglia, Halil İbrahim Ulusoy, Dora Melucci, Giuseppe Maria Merone, Abuzar Kabir, Cristian D'Ovidio, Fabio Maroni, Songül Ulusoy, Pantaleone Bruni, Fausto Croce, Serena Gabrielli, Marcello Locatelli, Tartaglia A., Kabir A., Ulusoy S., Ulusoy H.I., Merone G.M., Savini F., D'Ovidio C., de Grazia U., Gabrielli S., Maroni F., Bruni P., Croce F., Melucci D., Furton K.G., and Locatelli M.

Subjects
extraction procedure, Polymers, Pharmaceutical Science, Urine, 010402 general chemistry, 01 natural sciences, Article, parabens, Analytical Chemistry, Molecular Imprinting, lcsh:QD241-441, chemistry.chemical_compound, lcsh:Organic chemistry, Drug Discovery, Humans, Solid phase extraction, Physical and Theoretical Chemistry, Paraben, Polymer, chemistry.chemical_classification, Chromatography, Chemistry, Solid Phase Extraction, HPLC-PDA, 010401 analytical chemistry, Organic Chemistry, Extraction (chemistry), Molecularly imprinted polymer, biological matrix, MIP, 0104 chemical sciences, Characterization (materials science), Chemistry (miscellaneous), Molecular Medicine, Theoretical plate, Molecular imprinting, MIPs, Human, stationary phase characterization
Abstract

In this work, the synthesis, characterization, and application of novel parabens imprinted polymers as highly selective solid-phase extraction (SPE) sorbents have been reported. The imprinted polymers were created using sol&ndash, gel molecular imprinting process. All the seven parabens were considered herein in order to check the phase selectivity. By means of a validated HPLC-photodiode array detector (PDA) method all seven parabens were resolved in a single chromatographic run of 25 min. These SPE sorbents, in-house packed in SPE empty cartridges, were first characterized in terms of extraction capability, breakthrough volume, retention volume, hold-up volume, number of theoretical plates, and retention factor. Finally, the device was applied to a real urine sample to check the method feasibility on a very complex matrix. The new paraben imprinted SPE sorbents, not yet present in the literature, potentially encourage the development of novel molecularly imprinted polymers (MIPs) to enhance the extraction efficiency, and consequently the overall analytical performances, when the trace quantification is required.

Published
2019
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17. Diagnostic Failure of Ciprofloxacin-Induced Spontaneous Bilateral Achilles Tendon Rupture: Case-Report and Medical-Legal Considerations

Author

Cristian D'Ovidio, Andrea Pantalone, Michele Abate, Vincenzo Salini, Aldo Carnevale, Pantalone, A., Abate, M., D'Ovidio, C., Carnevale, A., and Salini, V.

Subjects
ecchymosi, medicine.medical_specialty, Immunology, Bronchiolitis obliterans, achilles tendon rupture, ankle pain, swelling, Pharmacotherapy, Tendinitis, ciprofloxacin, nonsteroid antiinflammatory agent, medicine, case report, Immunology and Allergy, human, Pharmacology, business.industry, adult, article, echography, medicine.disease, methylprednisolone, Tendon, Surgery, female, medicine.anatomical_structure, priority journal, Methylprednisolone, Concomitant, Orthopedic surgery, Achilles tendon rupture, medicine.symptom, business, edema, medicine.drug
Abstract

Rare side-effects of fluoroquinolone therapy are tendinitis and tendon rupture. Many reports have demonstrated that the concomitant use of corticosteroids, in patients aged 60 years or older, increase the risk substantially. We present a case of spontaneous bilateral Achilles tendon rupture induced by ciprofloxacin and methylprednisolone. A 61-year-old woman was diagnosed with Bronchiolitis Obliterans with Organizing Pneumonia (BOOP) and was started on oral ciprofloxacin 500 mg twice daily for 3 weeks and on oral methylprednisolone 16 mg twice daily for 2 weeks. The diagnosis was made after doctors, rather than stop drug therapy and advise complete rest, had mistakenly prescribed for the woman to undergo physiotherapy and local NSAIDs, thus favoring the onset of tendon ruptures and resulting in surgical and legal implications. Inspired by this case, we also submit a brief review on professional liability in Orthopaedics. Copyright © by BIOLIFE, s.a.s.

Published
2011
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