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Müller et al. re‐analysed published data on temporal variation in insect biomass in Germany between 1989 and 2016, with a focus on modelling the effects of weather conditions on insect biomass.These upgraded analyses, using an external validation dataset, are a nice demonstration of the strong impact of climatic conditions on annual insect biomass. However, Müller et al.'s conclusion that temporal variation in weather conditions explained most of the temporal changes in insect biomass was overstated. We argue that their methodological approach was unsuitable to draw such conclusion, because of omitted variable bias.We re‐ran the analyses of Müller et al. but accounting for a remaining temporal trend in insect biomass due to missing drivers. Our results suggest that the main conclusion of Müller et al. was wrong: there is a significant temporal decline in insect biomass that is not explained by weather conditions.Our commentary recalls that not accounting for missing predictors is likely to produce highly biased results, especially when missing predictors are correlated with the available ones, which is likely to be the case for most of the anthropogenic pressures linked to global change. This highlights the difficult challenge of estimating the relative importance of the global change components in driving the observed biodiversity changes. [ABSTRACT FROM AUTHOR]

Objective: To define the concept of surgeon-scientists and identify the root causes of their decline in number and impact. The secondary aim was to provide actionable remedies. Background: Surgeons who conduct research in addition to patient care are referred to as "surgeon-scientists." While their value to society remains undisputed, their numbers and associated impact have been plunging. While reasons have been well identified along with proposals for countermeasures, their application has largely failed. Methods: We conducted a systematic review covering all aspects of surgeon-scientists together with a global online survey among 141 young academic surgeons. Using gap analysis, we determined implementation gaps for proposed measures. Then, we developed a comprehensive rescue package. Results: A surgeon-scientist must actively and continuously engage in both patient care and research. Competence in either field must be established through protected training and criteria of excellence, particularly reflecting contribution to innovation. The decline of surgeon-scientists has reached an unprecedented magnitude. Leadership turning hospitals into "profit factories" is one reason, a flawed selection process not exclusively based on excellence is another. Most importantly, the appreciation for the academic mission has vanished. Along with fundamentally addressing these root causes, surgeon-scientists' path to excellence must be streamlined, and their continuous devotion to innovation cherished. Conclusions: The journey of the surgeon-scientist is at a crossroads. As a society, we either adapt and shift our priorities again towards innovation or capitulate to greed for profit, permanently losing these invaluable professionals. Successful rescue packages must not only involve hospitals and universities but also the political sphere. [ABSTRACT FROM AUTHOR]

The conservation status of monarch butterflies in North America is a topic of intense scrutiny and debate. It is clear that winter colonies in Mexico are declining, yet some recent studies suggest that summer breeding populations are relatively stable and similar to historical abundances. One possible explanation for these discordant patterns is that fall migration success has been recently disrupted. Here, we use a relatively unexplored citizen-scientist dataset on the size of monarch “roosts,” which are resting aggregations on vegetation, to infer changes in monarch abundance along the fall migration route over the last 17 y. We found that the timing of migration remained relatively unchanged while the flyway has generally become warmer and greener. Warmer and greener conditions were associated with larger roosts, yet we found steady, dramatic declines in roost sizes through time that were independent of climate and landscape factors. Roost sizes have declined as much as 80%, with losses increasing from north to south along the migration route. These findings suggest that failure during the fall migration could explain the apparent drop in monarch numbers from summer breeding to overwintering populations. This in turn suggests that conservation efforts that support fall migration success are most needed, such as providing high quality nectar plants along the migration route or limiting the planting of nonnative milkweeds that enhance monarch parasite loads. Overall, it appears the fall migration of monarch butterflies is under imminent threat, even if the species’ overall survival is not. [ABSTRACT FROM AUTHOR]

The opening of Spain's first railway in 1848 inaugurated a short-lived period of railway euphoria that consumed the imaginations of Spaniards and resulted in the rapid development of nearly 5,000 km of track. While most historians of Spain's nineteenth century concede that the effort failed to trigger the industrialization many had hoped for, it did stimulate the minds of those primed to fantasize about the Spanish future then being constructed with iron and steam. Fueling these dreams of a hyper-modernized future was the dark specter of Spanish decline, a narrative with roots in the seventeenth century and an influential cultural force in the nineteenth. Nineteenth-century railway boosters and journalists frequently conjured up stirring images of a prostrate Spain being lifted out of the mire of decline and re-joining the nations of Europe. This article explores how popular anticipation at the prospect of railways prompted an infectious feeling of possibility that echoed across Spain and promised, if only for a bright and fleeting moment, to ease Spanish insecurities and allow the nation to finally free itself of the terrible burden of its past failures. [ABSTRACT FROM AUTHOR]

Background: Untreated hearing loss has an effect on cognition. It is hypothesized that the additional processing required to compensate for the sensory loss affects the cognitive resources available for other tasks and that this could be mitigated by a hearing device. Methods: The impact on cognition of cochlear implants (CIs) was tested in 100 subjects, ≥60 years old, with bilateral moderately-severe to profound post linguistic deafness using hearing aids. Data was compared pre and 12 and 18 months after cochlear implantation for the speech spatial qualities questionnaire, Mini Mental State Examination (MMSE), Trail making test B (TMTB) and digit symbol coding (DSC) from the Wechsler Adult Intelligence Scale version IV and finally the timed up and go test (TUG). Subjects were divided into young old (60-64), middle old (65-75) and old old (75+) groups. Cognitive test scores and times were standardized according to available normative data. Results: Hearing significantly improved pre- to post-operatively across all age groups. There was no change post-implant in outcomes for TMTB, TUG or MMSE tests. Age-corrected values were within normal expectations for all age groups for the TUG and MMSE. However, DSC scores and TMTB times were worse than normal. There was a significant increase in DSC scores between baseline and 12-months for 60- to 64-year-olds (t[153] = 2.608, p = 0.027), which remained at 18 months (t[153] = 2.663, p = 0.023). Discussion: The improved attention and processing speed in the youngest age group may be a consequence of reallocation of cognitive resources away from auditory processing due to greatly improved hearing. The oldest age group of participants had cognition scores closest to normal values, suggesting that only the most able older seniors tend to come forward for a CI. Severe to profoundly deaf individuals with hearing aids or cochlear implants were still poorer than age-equivalent normally hearing individuals with respect to cognitive flexibility, attention, working memory, processing speed and visuoperceptual functions. Due to a lack of data for the TUG, TMTB and DSC in the literature for hearing impaired individuals, the results reported here provide an important set of reference data for use in future research. [ABSTRACT FROM AUTHOR]

The most severe risk during a fire in an underground mine is the smoke spread, forcing the personnel to evacuate and take shelter. This study investigates the sheltering effect of a cuddy during a fire in an adjacent mine drift or a decline. The aim of the paper is to perform a parametric study on the sheltering effect, accounting for parameters such as the length of cuddy and ventilation velocity. Data from fire experiments in a model-scale mine drift and results from CFD simulations were used during the study. It was found that for a fire in an adjacent mine drift, extending the cuddy length resulted in the best conditions and increasing the heat release rate resulted in the worst conditions. An extended cuddy length will result in increased heat losses of the smoke layer. For a fire in an adjacent downslope decline, extending the cuddy length or increasing the ventilation velocity resulted in the best conditions. The increased ventilation velocity will cause an increased cooling of the smoke volumes entering the cuddy. An increased heat release rate resulted in the worst conditions. For the upslope decline case, extending the cuddy length resulted in the best conditions and increasing the heat release rate or increasing the ventilation velocity resulted in the worst conditions. An increased ventilation velocity in an upslope decline case will lead to larger portions of hot gases entering the cuddy. [ABSTRACT FROM AUTHOR]

Because of their wide distribution, short life cycle, rapid reproduction, and sensitivity to the environment, rodents can indicate changes in habitat quality and climate variables. Long-term studies are needed to verify these changes and assumptions about their causes. We analyzed small mammal trapping data in Lithuania, covering the period 1975–2023, with 1821 trapping sites and 57,426 small mammal individuals, with a focus on the bank vole (Clethrionomys glareolus). The aim of this study was to assess temporal changes in the relative abundance and proportion of this species in small mammal communities in relation to their habitats. With 21,736 captured individuals, C. glareolus was a dominant species in the country; its proportion in general was 37.9%, with 60.0% in forests. Open habitats, meadows and agricultural land were characterized by the lowest species proportions. Our main findings were the confirmation of decreasing abundances and proportions of C. glareolus since the 1990s, the absence of cyclical fluctuations in the relative abundances of the species in general and in forest habitats, and the introduction of a south–north cline in species proportions. The status of this temperate and boreal forest species is subject to change, with implications for the diversity of the mid-latitude small mammal community. [ABSTRACT FROM AUTHOR]

The "limón sutil" (Citrus aurantifolia) has been widely cultivated and well established for many years in Piura, northwestern Peru, because of its exceptional climate and soil conditions. However, decline and death of C. aurantifolia trees caused by different phytopathogens remain a common problem which has been observed in the last decades. It is known that the microbiota of soil plays an important role with their host and could be the starting point to understand the causes of citrus decline. In this study, we identified through culture-independent methods the bacterial and fungal microbiota associated to C. aurantifolia, C. jambhiri and C. volkameriana rhizospheres in the main areas of Piura. By using a 16S rRNA and ITS-metabarcoding analysis, we evaluated the taxonomic diversity between healthy trees and with decline symptoms and how this diversity could influence the health status of citrus trees. More than 600 and 200 bacterial and fungal ASVs were identified, respectively. Our metabarcoding analysis was able to identify Proteobacteria, Cyanobacteria, Firmicutes, Bacteroidota and Acidobacteriota prokaryotic phyla, while fungal phyla included Ascomycota, Basidiomycota and Glomeromycota. In addition, there were differences between microbial diversity indices in rhizospheres evaluated. Finally, bacterial and fungal genera were shared among the different citrus rhizospheres. These results have allowed us to obtain a preliminary identification of microbiota in the citrus rhizospheres of healthy trees and with decline symptoms. [ABSTRACT FROM AUTHOR]

The “limón sutil” (Citrus aurantifolia) has been widely cultivated and well established for many years in Piura, northwestern Peru, because of its exceptional climate and soil conditions. However, decline and death of C. aurantifolia trees caused by different phytopathogens remain a common problem which has been observed in the last decades. It is known that the microbiota of soil plays an important role with their host and could be the starting point to understand the causes of citrus decline. In this study, we identified through culture-independent methods the bacterial and fungal microbiota associated to C. aurantifolia, C. jambhiri and C. volkameriana rhizospheres in the main areas of Piura. By using a 16S rRNA and ITS-metabarcoding analysis, we evaluated the taxonomic diversity between healthy trees and with decline symptoms and how this diversity could influence the health status of citrus trees. More than 600 and 200 bacterial and fungal ASVs were identified, respectively. Our metabarcoding analysis was able to identify Proteobacteria, Cyanobacteria, Firmicutes, Bacteroidota and Acidobacteriota prokaryotic phyla, while fungal phyla included Ascomycota, Basidiomycota and Glomeromycota. In addition, there were differences between microbial diversity indices in rhizospheres evaluated. Finally, bacterial and fungal genera were shared among the different citrus rhizospheres. These results have allowed us to obtain a preliminary identification of microbiota in the citrus rhizospheres of healthy trees and with decline symptoms.

Copyright of Contemporary Accounting Research is the property of Canadian Academic Accounting Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Purpose of Review: End stage kidney disease can be a slow process and it may be challenging to achieve required follow-up for sufficient events. Therefore, a surrogate kidney endpoint, such as estimated glomerular filtration rate (eGFR) slope maybe attractive to assess the kidney in cardiovascular trials, especially heart failure (HF). Recent Findings: eGFR slope can generate informative results in a shorter follow-up period, has decreased risk of type-2 error, and is less sensitive to eGFR shifts compared with other surrogate kidney endpoints (eGFR decline≥40% or doubling creatinine). However, eGFR slope has its limitations with acute effects, heterogeneity in slope calculation/reporting, and deviations from linearity. Summary: eGFR slope is a kidney endpoint which may be well-suited for HF trials. Cross-collaborated guideline recommendations are needed to optimize the use of eGFR slope as a kidney endpoint in patients with HF. [ABSTRACT FROM AUTHOR]

This study investigated regional and site level diversity for alpine and subalpine systems. The aim was to assess whether differing analytical methods could track diversity through time. The study was undertaken within Kosciusko National Park in south‐eastern Australia (6900 km2) which encompasses most of the alpine zone (~2500 km2 or 48% of its occurrence on mainland Australia). Multivariate ordination, species richness and the relationship of diversity to landscape patterns were assessed and considered in relation to changes predicted to impinge upon these systems over coming decades. Species richness had limited capacity to detect predicted changes; however, ordination based on floristic patterns may have more capacity to detect change if adequate replication is applied. Complex patterns across landscapes and at the site level contributed to these analytical challenges. Species richness is commonly used to assess ecosystem status and to provide benchmark values, but it had very limited capacity to do so in the assessed alpine and subalpine ecosystems, including the most threatened. Government agencies often rely heavily on species richness to assess ecosystem change and this urgently needs re‐evaluation. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In September 2022, hazelnut trees in six orchards in the Çarşamba district of Samsun province, a major hazelnut production area in the Black Sea region of Türkiye, showed symptoms of leaf yellowing, shoot dieback, decline, basal stem rot and the presence of brown bracket‐like sessile basidiocarps. Approximately 5%–10% of hazelnut trees were affected, highlighting the significant impact of the disease. A comprehensive morphological analysis was conducted to characterize fungal isolates obtained from symptomatic tissues as G. adspersum. This analysis incorporated features observed in basidiomata from declining trees and those reproduced after isolates were cultivated on wheat grain for spawn production and grown on an oak sawdust‐based substrate. Confirmation of identification was achieved through the utilization of the internal transcribed spacer (ITS), large subunit (LSU) and small subunit (SSU) loci, along with sequencing and subsequent phylogenetic analysis. The G. adspersum isolates generally exhibited no significant growth differences at similar temperatures but demonstrated enhanced growth at 30°C, while growth was completely inhibited at 40°C. Incompatible reactions between isolates confirmed that distinct genotypes were present, highlighting genetic diversity within the species. In the pathogenicity trials, employing a single infested wheat grain per inoculation at the wounded site, hazelnut suckers exhibited distinct brown discolouration surrounding the inoculation site following a 2.5‐month incubation period. Significantly, lesions exceeding 3 cm in length were observed, providing clear evidence of vigorous pathogenic activity by G. adspersum. This study is the first report of G. adspersum causing butt rot in hazelnuts, underscoring the significance of this finding for hazelnut cultivation and providing a foundation for future research and disease management strategies. [ABSTRACT FROM AUTHOR]

As the second-largest city in Iran, Mashhad has a rich history in the gold industry. Mashhad's gold and jewellery innovation ecosystem (MGJIE) is now at a stage of decline, and renewal or sharp decline cycles lie ahead. This article explores these two scenarios and their implications for the innovation ecosystems of this industry. The first objective is to imagine the future of the MGJIE using a normative approach and formulate policies to realize an optimistic future. The second objective is to investigate the pessimistic scenario and its implications for the ecosystem. The normative scenarios are created for a 2032 horizon using the back casting method. With regard to the second objective, the exploratory approach is used for the 2047 horizon. In both objectives, 46 questionnaires and fifteen interviews are used. In the normative scenario, nine drivers are identified. In the exploratory approach, three scenarios are formulated, while in the last scenario, with the occurrence of four steps of the renewal plan, improving the performance of the ecosystem is guaranteed. Innovation is a by-product of scenario thinking. The combined application of innovation ecosystem and scenario planning in the jewellery industry has not previously been the focus of research in Iran or other countries. [ABSTRACT FROM AUTHOR]

This article argues that conditions favor American retrenchment from the Middle East because the United States can shift burdens to capable states in the region, there are few areas where US commitments are interdependent, and the local conquest calculus favors defense. Forward military deployments do not positively influence potential threats in the Middle East, and maintaining deployments there will detract from meeting challenges from China. Through comparisons to prior cases of great-power ordinal decline, this article puts America's modest decline in historical perspective and finds that retrenchment policies will likely have positive consequences. [ABSTRACT FROM AUTHOR]

Declined card transactions present a significant problem for the payment industry, causing inconvenience for consumers, lost sales for merchants and lost revenue for card issuers. An analysis of card-based e-commerce across the EEA and UK indicates a decline rate of 10 per cent for domestic transactions and 18 per cent for cross-border transactions, leading to a total declined value of €60bn per annum. Using data obtained from different sources, including merchants' own records, and gateway, acquirer and scheme data, this paper identifies the main reasons why transactions are rejected, grouping them into four categories: valid business declines, avoidable business declines, risk-based declines, and technical declines. The study argues that merchants should focus on reducing decline rates in the latter three categories. Approaches might include use of the schemes' account updater service; localisation of acquiring to the same country as the card issuer, where possible; smart routing to acquirers with higher success rates for the given transaction attributes; use of network tokens; leveraging of strong customer authentication exemption rules; and correction of technical issues in authorisation requests, such as incorrect setting of flags indicating the acceptance environment. According to PSE's analysis, actionable codes account for around 25 per cent of all declines, totalling €15bn of transaction value (and €74m lost interchange for issuers). The paper therefore suggests that those merchants that are prepared to investigate and analyse the underlying causes of their declines have much to gain. [ABSTRACT FROM AUTHOR]

Arthropod faunas have become impoverished in recent years in abundance as well as in diversity, but so far little evidence exists concerning spiders. In 2022, we repeated pitfall trap collections of spider assemblages completed 25 years previously in coastal dune habitats of the Hanstholm Reserve of National Park Thy, Denmark. Traps were placed approximately at the same spots, i.e. the habitats (white dune, grey dune, dry dune heathland, wet dune heathland, low pine plantation) were represented approximately as before. Contrary to most previous reports of insect decline, we found only weak evidence of reduction in abundance, but strong indications of reductions in faunistic value based on changes in ecological traits. Within the same period of spring and with the same number of traps, we collected 12% fewer spider individuals and 13% fewer species; rarefaction indicated that the lowered species richness was real. Species diversity had decreased and dominance increased. Changes in indices of ecological traits showed that the fauna had changed into decreased contribution of habitat specialists and species of restricted Danish distribution; the proportion of aeronauts had increased; the average body size had decreased. Indices of assemblage microclimatic niche positions and niche widths showed increased representation of shade and humidity loving species. Most of these changes were repeated in each of the habitats. Finally, we found evidence of a phenological shift towards activity earlier in spring in some species. Implications for insect conservation: We discuss possible management measures to counteract the observed trend towards reduced faunistic value. [ABSTRACT FROM AUTHOR]

Alder yellows (ALY) phytoplasma (16SrV-C) is associated with ALY, a disease of several Alnus (alder) species in Europe and A. rubra in North America. In all affected species, the symptoms are similar. However, latent infections are common. ALY phytoplasma includes different strains which may be occasionally transmitted to grapevines leading to some grapevine yellows diseases. In the current study, visual symptom assessment and PCR-based methods using universal and group-specific phytoplasma primers were used to update and extend knowledge on the occurrence, impact, and genetic diversity of ALY phytoplasma in declining and non-symptomatic A. glutinosa and A. cordata trees in the Basilicata and Campania regions of southern Italy. ALY phytoplasma was detected in 80% of alder trees examined. In symptomatic trees, no other cause of disease was observed. More than half of alder trees that tested phytoplasma-positive proved to be latently infected. A considerable genetic variability was observed among the newly recorded ALY phytoplasma strains in southern Italy in almost of the genes examined. These included 16S rRNA, 16S/23S rDNA spacer region, ribosomal protein rpsV (rpl22) and rpsC (rps3), map, imp, and groEL genes. Eleven new genotypes were identified at map gene sequence level. However, the genetic differences observed were not related to plant host species, geographical origin, and symptoms shown by infected alder trees. Also, this study indicates that ALY phytoplasma is more widespread than previously thought. [ABSTRACT FROM AUTHOR]

Spot-tailed Earless Lizards (STEL; Plateau STEL, Holbrookia lacerata; and Tamaulipan STEL, Holbrookia subcaudalis) are lizard species that are in decline both in number and distribution. As a result, this species has been considered for federal threatened status and a 90-day finding by the United States Fish and Wildlife Service stated that federal protection may be warranted. To date, a decision for Endangered Species Act listing for the Plateau STEL has been denied, but a judgement for the Tamaulipan STEL has not yet been decided. The requests to list STEL as a threatened species initiated numerous studies to investigate the status of both species and to add to the knowledge base of STEL. Though many studies have been conducted, much of the resulting information exists in gray literature (e.g., governmental reports, project summaries, etc.) that are not readily available or peer-reviewed. Herein, we consolidate the research results from scientific literature, governmental reports, and petitions to assist future researchers of STEL. We describe the natural history of STEL, their current taxonomy, conservation status, and discuss potential causes for their decline. Our goal is to provide the needed background knowledge for future researchers and policy makers.

BackgroundUntreated hearing loss has an effect on cognition. It is hypothesized that the additional processing required to compensate for the sensory loss affects the cognitive resources available for other tasks and that this could be mitigated by a hearing device.MethodsThe impact on cognition of cochlear implants (CIs) was tested in 100 subjects, ≥60 years old, with bilateral moderately-severe to profound post linguistic deafness using hearing aids. Data was compared pre and 12 and 18 months after cochlear implantation for the speech spatial qualities questionnaire, Mini Mental State Examination (MMSE), Trail making test B (TMTB) and digit symbol coding (DSC) from the Wechsler Adult Intelligence Scale version IV and finally the timed up and go test (TUG). Subjects were divided into young old (60–64), middle old (65–75) and old old (75+) groups. Cognitive test scores and times were standardized according to available normative data.ResultsHearing significantly improved pre- to post-operatively across all age groups. There was no change post-implant in outcomes for TMTB, TUG or MMSE tests. Age-corrected values were within normal expectations for all age groups for the TUG and MMSE. However, DSC scores and TMTB times were worse than normal. There was a significant increase in DSC scores between baseline and 12-months for 60- to 64-year-olds (t[153] = 2.608, p = 0.027), which remained at 18 months (t[153] = 2.663, p = 0.023).DiscussionThe improved attention and processing speed in the youngest age group may be a consequence of reallocation of cognitive resources away from auditory processing due to greatly improved hearing. The oldest age group of participants had cognition scores closest to normal values, suggesting that only the most able older seniors tend to come forward for a CI. Severe to profoundly deaf individuals with hearing aids or cochlear implants were still poorer than age-equivalent normally hearing individuals with respect to cognitive flexibility, attention, working memory, processing speed and visuoperceptual functions. Due to a lack of data for the TUG, TMTB and DSC in the literature for hearing impaired individuals, the results reported here provide an important set of reference data for use in future research.

AbstractThis text aims to conduct a historical analysis of the development of the Semarang-Joana Tram Company or Stoomtram Maatschappij (SJS) in the railway map of Indonesia from the Dutch Colonial era to the Post-Independence period. The analysis employed historical methods, relying on primary sources obtained from Dutch and Indonesian archives and libraries, as well as interviews, site visits, and focus group discussions. The results showed that historical situation factors significantly determined the culture and performance of SJS companies. During the Dutch Colonial period, this situation strongly supported the growth and development of the company due to being assisted by ‘an open-door policy’ that provided foreign capital. Furthermore, the external factors that benefited the success of the SJS company at the beginning of its development included the following: (1) the ease of processing land for the railway, (2) the establishment of a previously designed railway, (3) the growth of plantation companies, (4) plantations, and (5) urban population improvement. The political changes during the Japanese military occupation led to the integration of SJS management into the government railway management under the Rikuyu Sokkyoku Administration. After Indonesia gained independence, SJS was nationalized and managed under the same administration as the Government Railway Department, which later became PT Kereta Api Indonesia. The shift in management from a private company to a government entity resulted in a decline in SJS performance.

This article critically examines the commonly held narrative of decline, in relation to the development of natural sciences in Islamic history. The period between the 16th and 19th centuries CE is often referred to as a time of decline for Islamic civilisation. Conversely, this period is also considered an important time for the European Renaissance and its modern age, including in terms of natural sciences. In this article, I argue that, while attempts to periodise Islamic history can facilitate better understanding of historical developments, they are often significantly influenced by underlying biases aimed at exerting dominance over the Muslim world. I have found the narrative of decline is closely connected to the linear movement theory of history. Furthermore, Egyptian modernists used the decline narrative to criticise al-Azhar without acknowledging its scholars' support for progress. Lastly, the narrative of decline built by modernists against al-Azhar for not paying attention to the natural sciences needs to be critically reviewed, particularly by referring to manuscripts written by al-Azhar scholars related to natural sciences, such as medicine, algebra, astronomy and engineering from the 16th to 19th centuries as a counternarrative of decline. [ABSTRACT FROM AUTHOR]

In this study, I argue that Josephus' interpretation of the period of the biblical judges, following the conquest of Canaan and settlement in the land, mirrors Greco-Roman rhetoric that traced the origins of Rome's decline to the middle and late republic. Survey of Greco-Roman writers shows that Josephus modelled his diagnosis of the decline of Israel during the period of the judges on the causes of Roman decline identified by many Greek and Latin writers, these being: (1) influx of foreign wealth; (2) discharge of veterans and turn toward agricultural living; and (3) growth of rural elite estates. Beyond serving as his own inspiration, this literary milieu informed Josephus' elite Greco-Roman audience, thus ensuring that they would read his interpretation of the period of the judges in light of tropes about Roman decline that were popular in their day. [ABSTRACT FROM AUTHOR]

Mangrove ecosystems are crucial for biodiversity and coastal protection but face threats from climate change and human activities. This review assesses the productivity of the Matang Mangrove Forest Reserve (MMFR) in Malaysia, which is recognised as one of the best-managed mangrove forests, while also addressing challenges such as deforestation and climate change-induced factors. This review explores the concept of productivity in mangrove forests, highlighting their role in carbon sequestration and discussing litterfall measurements as fundamental metrics for assessing primary productivity. An analysis of historical changes in MMFR's biomass and productivity revealed fluctuations influenced by logging, reforestation, and climatic conditions. Trends in MMFR productivity indicate a concerning decline attributed to anthropogenic activities such as aquaculture and industrial projects. A regression analysis conducted on Rhizophora apiculata data with age as the predictor and AGB as the response variable indicated a positive trend (slope = 3.61, R-squared = 0.686), suggesting a quantitative increase in AGB with age. Further analysis revealed a significant negative trend in MMFR's overall productivity over years (coefficient = −3.974, p < 0.05) with a strong inverse relationship (rho = −0.818, p < 0.05), indicating declining AGB trends. Despite these challenges, this review underscores the significance of sustainable management practices, effective conservation efforts, and community engagement in maintaining mangrove ecosystem health and productivity. In conclusion, sharing management lessons from MMFR can contribute to global conservation and sustainable mangrove forest management efforts, fostering resilience in these vital ecosystems. [ABSTRACT FROM AUTHOR]

The groundwater level decline has caused an environmental issue in most of the Iranian aquifers. In this regard, aquifer storage and recovery (ASR) system can be used as a solution. On the other hand, the huge volume of treated wastewater in big cities can be used as a water source for aquifer storage purpose. In this study, the treated wastewater, soil and groundwater quality have been investigated through the unsaturated-saturated porous media. An experimental model, as L-shaped, has been designed using PVC pipe material with a diameter of 200 mm and a length of 15 m (2.5 m vertical and 12.5 m horizontal). The wastewater used in this research was obtained from the outlet of the sewage treatment plant in the south of Tehran. In order to avoid changes in the quality of wastewater during storage in the tank, it was tried to a regular change the treated wastewater in short intervals. After the initial investigations, a zone situated in center of in the Feshafuye plain, has been selected for treated wastewater injection. Then the required soil for laboratory setup has been collected for tis area. In this regard, firstly, the surface layer soil was removed, then the subsurface soil was transferred to the laboratory for the experimental setup. The required inflow water for this setup was taken from the aquifer of the same area and was changed regularly in order to establish the maximum real conditions. During this study, treated wastewater have been sampled and analyzed at 12 points along the flow path for 60 days. The results showed that the nitrate concentration decreased to less than 0.5 ppm after 7 m and microbial pollutants, total coliform and E. coli had been removed in a 100-cc sample after 6 m. In terms of salinity, the treated wastewater and soil quality have been improved from an EC of 4 to 3.3 dS/m. The BOD and COD have decreased by 81% and 87%, respectively. Due to improvement of treated wastewater quality through the unsaturated- saturated porous media, the ASR system can be implemented as a solution to prevent the groundwater level decline. [ABSTRACT FROM AUTHOR]

Introduction: Characterized by its Shiite background and the interdependence of religion and politics in governance, the Safavid government bear some significant similarities to the Islamic Republic of Iran and played an important role in shaping Iran's political and social history. The aim of the present research is to examine the causes of the decline and fall of the Safavid government and to investigate the strategies that could have served as a solution to this decline for the Safavids To this end, after a historical investigation, Resaale-ye Teb-ol Mamaalek (the Treatise on State Medicine) written by Qutb al-Din Nayrizi has been chosen as the textual reference to analyze and achieve the research goal. This selection is of great importance due to Qutb al-Din Nayrizi's religious status and his contemporaneity with the reign of Shah Sultan Hussein Safavid (during whose period the fall of the Safavids occurred), and it can significantly reflect the political and social conditions of that era and elucidate Nayrizi's prescriptions for strengthening the political and social foundations of Safavid Iran and overcoming the state of weakness. Method: Due to the text-oriented nature of the current research, the authors will use the thematic analysis, which is more applicable to written sources. Accordingly, the materials related to the topic were extracted, categorized and coded. Relying on the stated methodological steps, in order to discover the existing topics of the text of Resaale-ye Teb-ol Mamaalek (the Treatise on State Medicine), the extraction and coding process of the topics in each section has been done by the researchers. Therefore, using MaxQDA software, categories related to the factors of decline and the strategies to prevent it were marked with the symbols Fa and So, and the coding process was carried out. Results and Discussion: In the end, the extracted themes were categorized under two main headings: causes of decline and strategies for overcoming the crisis. Through this process, the influential factors in each of these two headings were identified from Qutb al-Din Nayrizi's perspective, and the position of various factors in his thought was recognized. According to the author of this treatise, if the scholars, as one of the important social groups, are weak-willed, worldly, hypocritical, followers of the Sultan, and inactive, the groundwork for societal decline is laid. Nayrizi also mentions "environmental factors," including widespread famine and foreign territorial expansionism, and "divine trials and traditions" as causes of societal decline. Conclusions: According to the findings, it can be concluded that this religious thinker classified the factors of degeneration into the following five categories: factors related to the public, factors related to scholars, factors related to governance, environmental factors, and also divine traditions; he also classified the solutions to deal with it under four categories: solutions related to the public, solutions related to the scholars, solutions related to governance, and finally, transcendental solutions or divine aid. [ABSTRACT FROM AUTHOR]

This paper examines the decline of the fraternity of St. George in Nottingham between 1459 and 1546. It uses the guild's accounts in conjunction with Nottingham's rich surviving documentary materials to investigate the financial management of the fraternity by its officers. It argues that the officers were adept at negotiating shifting economic conditions by switching between various revenue streams. However, this adroit management did not stem the tide of membership decline. It discusses the role of religious reform in the guild's ultimate demise. It investigates why the decline in membership started long before any moves towards state-sponsored religious reform in the 1540s. It examines the impact of key individuals upon the guild's history. It argues that, for a more nuanced view of the decline of fraternal organizations in this period, a recognition of individuals' impact upon institutions needs to be incorporated into our understanding of institutions' influences upon the economy. [ABSTRACT FROM AUTHOR]

Summer skiing on glaciers is a leisure activity highly dependent on natural factors like weather and glacier conditions. While the literature agrees that climate change is shaping the fate of summer skiing, longer time series covering both the supply and demand side of glacier/summer skiing, and research that combines natural and non-natural factors affecting the summer ski market are missing. To close this research gap, we conducted a detailed supply-side analysis of nine Austrian glacier ski areas focusing on the number of operating days (in the summer half-year, as well as for meteorological and astronomical summer ski definitions), show how these numbers evolve over time, test how they correlate with meteorological and glaciological data using time-series regression models on a yearly and monthly basis, and highlight how managerial decisions come into play when trying to explain the summer ski supply's decline. Between 2002 and 2019, summer ski operating days in Austrian glacier ski areas declined by 48.3% in the summer half-year, 65.2% in the meteorological, and 62.3% in the astronomical summer parallel to rising mean temperatures and shrinking glaciers. This decrease is strongest in June to September and weakest in May and October but in two glacier ski areas, the operating days in the summer season remain constant or are even on the rise. This is in line with model results indicating that meteorological and glaciological data only explain parts of the variance of the decline trends. Operators' agency, strategies, and decisions play an important role underlining that global warming is not monocausally determining summer ski operation. [ABSTRACT FROM AUTHOR]

Synthesizing various studies that follow technology beyond innovation and use, this article aims to continue widening the scope of history of technology toward this perspective. It argues that we must follow technology through time and—in addition to its use—its maintenance and repair, while also addressing its so-called afterlife, encompassing topics such as reuse, reconfiguration and/or restoration, decline or deliberate ruination, abandonment, and removal and/or remains. Recent studies of these issues underscore that the temporality of technology does not end with the end of its use, suggesting instead multilayered temporalities. History of technology is thus challenged to rethink some of its established and largely unquestioned approaches, such as the "innovation timeline", the model of "technology diffusion and substitution", and "lifecycle" metaphors borrowed from twentieth-century theories of economic growth and innovation. [ABSTRACT FROM AUTHOR]

The British Yiddish writer Katie Brown wrote humorous stories and sketches for the London Yiddish newspapers Di post (The Post) in the 1930s and Di tsayt (The Times) in the 1940s. The stories, set in London’s Jewish East End, concern the day-to-day effects of immigration, poverty, and Jewish culture in Britain. After the Second World War, in a bombed-out East End where Jewish migration to the suburbs was accelerating, Brown did not write entirely new sketches, but rather edited versions of her prewar stories. Looking at the earlier and later stories together, we get a sense of the changes happening to London’s Jewish community: the decline of Jewish culture and religious practice, the changing relationship with the Eastern European homeland, and the decline of the Yiddish language. Through close reading and analysis, this article gives historical background to Brown and the social, cultural, and political context of her stories. It situates Brown as the only female journalist writing regularly for the press and identifies her unique perspective in making poignant interventions into Jewish debates of the day through stories of small incidents in family life. She raises questions around how to maintain a Jewish identity in England and visibility as a Jew in a Christian world, and traces change through two decades by describing the tension between the immigrant generation and their children. Using a range of neglected source material in Yiddish, this article throws new light on the Jewish East End in its twilight years. [ABSTRACT FROM AUTHOR]

This paper focuses on George Du Maurier's 'chinamania' cartoons that were published in the popular British satirical magazine Punch. Depictions of languid men and selfish women obsessed with blue and white china (the porcelain), a familiar symbol of China (the country), visualised anxieties over degeneration at a time when China was viewed as a regressive civilisation. By exploring late nineteenth century notions of decline, this paper argues that Du Maurier's series of cartoons simultaneously mocked English societal foibles while positioning China to serve as a visual warning of wider issues concerning the degeneration of society and by extension, the British nation and its standing in the international arena. [ABSTRACT FROM AUTHOR]

Children with sickle cell disease (SCD) may experience cognitive difficulties, including slowed processing speed. Thus, we investigated if processing speed changes over time. From 1992–2001, 103 participants with SCD aged 3–16 years (n ≤ 8.99 = 45; n ≥ 9.00 = 58) completed cognitive assessments. MRI was available for 54 participants. Between 1992–2002, 58 participants consented to one or two further assessments. A repeated measures regression using linear mixed-effects modelling determined longitudinal changes in processing speed index (PSI), examining the interaction between age (continuous variable) and timepoint (i.e., assessment 1 or 3) and controlling for MRI infarct status (i.e., no infarct, silent infarct, or stroke). Those aged ≤8.99 and ≥9.00 at first assessment experienced PSI decline. Declines were most prominent for the processing speed coding subtest, with a significant interaction between timepoint and age, t(31) = 2.64, p = 0.01. This decline may reflect a developmental delay, likely due to disease progression, with slower improvements in processing speed. Although there have been significant improvements in SCD treatments, mostly in high-income countries, processing speed still remains a target; thus, incorporating clinical monitoring of processing speed may help identify delay and allow for early intervention. [ABSTRACT FROM AUTHOR]

The study, conducted in Manso Amenfi, Western Region, Ghana, explored the livelihood implications of transitioning from cocoa to rubber plantations. Using a cross-sectional survey with 384 participants, data revealed a decline in cocoa production levels. The socioeconomic factors that influence farmers’ land use shift behaviour were age, household size, being a household head, farm size, educational level, access extension and labour availability. The knowledge factor that was ranked first as influencing farmers shift behaviour was high price of rubber while the behavioural factor was the farmers’ personal belief that rubber plantation will do well than cocoa. The farmers agreed that rubber plantation has effect on their livelihood. The study recommends interventions to make cocoa cultivation more profitable, addressing concerns like low prices, pests, diseases, and soil fertility, emphasizing the need for support from agricultural extension officers, the Ghana Cocoa Board, and the government.

The article is devoted to the history of the functioning of the movement «Democratic Russia» and, first of all, the Nizhny Novgorod branch of this structure. The aim of the work is to identify the features of the political activity of the movement «Democratic Russia» in 1990–1992 in the Nizhny Novgorod region. The tasks of the work are related to the identification of the most significant Nizhny Novgorod representatives of the movement, as well as the causes of splits in the organization. It is revealed that the reasons for the weakening and extinction of the movement «Democratic Russia» are almost the same both in the center and at the regional level.

Because of their wide distribution, short life cycle, rapid reproduction, and sensitivity to the environment, rodents can indicate changes in habitat quality and climate variables. Long-term studies are needed to verify these changes and assumptions about their causes. We analyzed small mammal trapping data in Lithuania, covering the period 1975–2023, with 1821 trapping sites and 57,426 small mammal individuals, with a focus on the bank vole (Clethrionomys glareolus). The aim of this study was to assess temporal changes in the relative abundance and proportion of this species in small mammal communities in relation to their habitats. With 21,736 captured individuals, C. glareolus was a dominant species in the country; its proportion in general was 37.9%, with 60.0% in forests. Open habitats, meadows and agricultural land were characterized by the lowest species proportions. Our main findings were the confirmation of decreasing abundances and proportions of C. glareolus since the 1990s, the absence of cyclical fluctuations in the relative abundances of the species in general and in forest habitats, and the introduction of a south–north cline in species proportions. The status of this temperate and boreal forest species is subject to change, with implications for the diversity of the mid-latitude small mammal community.

As Michel Houellebecq's flirtation with the far-Right has grown more explicit, critics have had difficulty reconciling his politics with his novels. Specifically, his peculiar variety of decadent anti-humanism mixes oddly with his nostalgic French populism. In this article I attempt to address the seeming contradictions in his political positions and argue that Houellebecq should be taken seriously as an author within a specifically French tradition. Exploring his last four novels, I approach the question of Houellebecq's politics as it relates to his ambivalent relationship to France. Within these works I note his use of lieux de mémoire—that is, places where his heroes journey to 'try on' various solutions. Michel Houellebecq has repeatedly taken us to locales which had been rich with French memory and identity, but which now appear unreachable, and has used these tableaux to ponder French decline. Throughout, I argue that his work has become, increasingly, a meditation on loss and the inaccessibility of national identity, and that, within a specifically French context, Houellebecq borrows not just from Charles Maurras and French reaction, but from an overdetermined discourse inherited from the 1930s. [ABSTRACT FROM AUTHOR]

Background: Child sex ratio signifies the proportion of girls compared with boys in 0 to 6 years of age group. It is an important indicator for any population and most significantly about the status of the girl child in the society. The study tried to approach in a qualitative manner to study the rationale behind the declining of child sex ratio. Materials and Methods: We conducted a qualitative study using five focus group discussions and 12 in-depth interviews among various age groups, pregnant women, and other stake holders. The participants were approached with a semi-structured open-ended interview guide regarding the rationale of declined child sex ratio and measures to normalize it. After a thematic analysis, main themes and subthemes were selected after consensual agreement. Results: The study showed that male child preference is the main theme identified in the rationale part with subthemes of female vulnerability, socioeconomic status, literacy, cultural, and caste and religion as subthemes. The theme of female child preference also came up with as second child, care taking, affectionate, and cultural factors as subthemes. In the area of suggestions/ interventions, education, counseling, government policies and media along with suggestions regarding sex determination and female feticide were identified. Conclusion: The decline in child sex ratio should be taken as an active social issue thus focusing more into female upliftment and enlightening into the issues of patriarchal nature, with reduction of cultural/religious beliefs. [ABSTRACT FROM AUTHOR]

Empires are an extraordinary phenomenon in the history of mankind. The study of empires requires scientific understanding, thoughtful comparison and deep analysis. Such way of studding the comparative approach of the problem has arisen that will help us understand the nature of the emergence and disappearance of imperial formations, find answers to difficult questions: how empires grew, for what reasons some of them were powerful and others weak, why some empires disappeared and others flourished (John Hutchinson, 2017). Is there a connection between the instability of power, coups and the death of empires? And finally, what are the consequences for world development of the disappearance of imperial formations. Among the reasons for the demise of empires, researchers single out political and economic problems, social and cultural issues, and environmental challenges. The author of the article tries to explain how the Moscow Empire was formed and how the Russian Empire manages to survive despite a number of dangerous challenges. In the submitted article prof. L.Chekalenko for the first time revealed the phenomenon of "saving" the empire in historical and political dimensions. The author discovered that Russia was saved by its vassals - conquered peoples. So, the article examines the factors that support and revive imperial formations, and also makes cautious assumptions about the future scenarios of the development of events surrounding the current situation. [ABSTRACT FROM AUTHOR]

Background and objectives: Carpinus orientalis Mill is a native tree growing in the forests of northern Iran. This tree-shrub plant is shorter and more branched compared to hornbeam (Carpinus betulus L.) and thrives in sunny and rocky areas. The Cytospora genus is known as a primary agent of canker, causing damage to trees affected by stress factors such as water stress, frost stress, sunburn, or mechanical damage (caused by non-living and living agents such as insects). Disease occurrence by different species of Cytospora spp. has been reported in a wide range of hosts, including species from the genera Populus, Salix, Acer, Ulmus, Alnus, Fraxinus, Prunus, Sorbus, Cydonia, Amelanchier, and many others. Methodology: To identify the causes of oriental Hornbeam decline in Mazandaran province, samples from infected tissue were collected and transferred to the laboratory for fungal isolation. The most prominent symptoms of the disease were shoot dieback and dead or dying branches visible from a distance. In humid weather, cankers exuded clear amber resin, which eventually formed a clear white crust on the branches. In young seedlings, dried leaves remained on the branches, and the seedlings were completely desiccated, indicating the high severity of the disease. Fungal isolates were obtained by removing a mucoid spore mass from conidiomata (from the canker areas) and by disinfecting and culturing infected tissue on Potato- Dextrose-Agar (PDA) medium, incubated at 23±2°C in darkness. After purification of the fungal isolate by single spore, various morphological characteristics including spore shape and size, colony diameter, growth rate, and pigment production were evaluated on PDA medium. Results: The fungus grew rapidly on PDA and produced cream-white to hyaline, moderate to profusely cottony aerial hyphae. Conidia were hyaline, unicellular, with thin walls and no septa. A transverse section of the infected tissues showed long conidiophores inside the fungal stromata. Based on morphological characteristics, the fungus was identified as Cytospora sp. The morphological results indicated a similarity between this isolate and C. decipiens species. This is the first report of 'Carpinus orientalis decline' caused by Cytospora species in Iran. Conclusion: Investigating the epidemiology and management of cytosporic canker disease is of particular importance because its development is expected to intensify under future drought and climate stress conditions. Currently, due to increasing reports of decline caused by Cytospora, especially in Hornbeam species, the lack of information about the host range and epidemiology of the fungus, and the possible role of climate change in disease development, it is clear that this disease warrants further study. [ABSTRACT FROM AUTHOR]

Background/Aim: Emerging evidence suggests that there is a close relationship between the human lung and kidney. This study evaluated whether decreased renal function was associated with accelerated pulmonary function decline in a large-scale community-based cohort. Patients and Methods: A total of 10,028 subjects of the prospective Ansung-Ansan cohort were eligible for the longitudinal analysis of changes in pulmonary function associated with decreased renal function (glomerular filtration rate <60 ml/min/1.73 m²). Logistic regression analysis was performed to evaluate factors associated with decreased baseline renal function, and a linear mixed model compared changes in pulmonary function in participants with and without decreased renal function after propensity score matching (PSM). Results: At baseline, subjects with and without decreased renal function showed distinct characteristics, and the factors associated with decreased renal function were age, baseline forced vital capacity, hypertension, and white blood cell (WBC) count. A 1:4 PSM of age, sex, body mass index, and smoking status showed that the proportion of those with hypertension and the WBC count differed between the patients with decreased and normal renal function. In the PSM population, those with decreased renal function had a greater decline in forced expiratory volume in the first second (FEV1) than those without (p=0.0402); however, these differences were not found to be evident when hypertension and WBC count were further matched (p=0.0807). Conclusion: The results of our study demonstrated that decreased renal function was not directly associated with the rapid decline in pulmonary function in a community-based general population setting. [ABSTRACT FROM AUTHOR]

With environmental change, understanding how species recover from overharvesting and maintain viable populations is central to ecosystem restoration. Here, we reconstruct 90 years of recovery trajectory of the Antarctic fur seal at South Georgia (S.W. Atlantic), a key indicator species in the krill‐based food webs of the Southern Ocean. After being harvested to commercial extinction by 1907, this population rebounded and now constitutes the most abundant otariid in the World. However, its status remains uncertain due to insufficient and conflicting data, and anthropogenic pressures affecting Antarctic krill, an essential staple for millions of fur seals and other predators. Using integrated population models, we estimated simultaneously the long‐term abundance for Bird Island, northwest South Georgia, epicentre of recovery of the species after sealing, and population adjustments for survey counts with spatiotemporal applicability. Applied to the latest comprehensive survey data, we estimated the population at South Georgia in 2007–2009 as 3,510,283 fur seals [95% CI: 3,140,548–3,919,604] (ca. 98% of global population), after 40 years of maximum growth and range expansion owing to an abundant krill supply. At Bird Island, after 50 years of exponential growth followed by 25 years of slow stable growth, the population collapsed in 2009 and has thereafter declined by −7.2% [−5.2, −9.1] per annum, to levels of the 1970s. For the instrumental record, this trajectory correlates with a time‐varying relationship between coupled climate and sea surface temperature cycles associated with low regional krill availability, although the effects of increasing krill extraction by commercial fishing and natural competitors remain uncertain. Since 2015, fur seal longevity and recruitment have dropped, sexual maturation has retarded, and population growth is expected to remain mostly negative and highly variable. Our analysis documents the rise and fall of a key Southern Ocean predator over a century of profound environmental and ecosystem change. [ABSTRACT FROM AUTHOR]

To evaluate conservation interventions, it is necessary to obtain reliable population trends for short (<10 years) time scales. Telemetry can be used to estimate short‐term survival rates and is a common tool for assessing population trends, but it has limitations and can be biased toward specific behavioral traits of tagged individuals. Encounter rates calculated from transects can be useful for assessing changes across multiple species, but they can have large confidence intervals and be affected by variations in survey conditions. The decline of African vultures has been well‐documented, but understanding of recent trends is lacking. To examine population trends, we used survival estimates from telemetry data collected over 6 years (primarily for white‐backed vultures [Gyps africanus]) and transect counts conducted over 8 years (for 7 scavenging raptors) in 3 large protected areas in Tanzania. Population trends were estimated using survival analysis combined with the Leslie Lefkovitch matrix model from the telemetry data and using Bayesian mixed effects generalized linear regression models from the transect data. Both methods showed significant declines for white‐backed vultures in Ruaha and Nyerere National Parks. Only telemetry estimates suggested significant declines in Katavi National Park. Encounter rates calculated from transects also showed declines in Nyerere National Park for lappet‐faced vultures (38% annual declines) and Bateleurs (18%) and in Ruaha National Park for white‐headed vultures (Trigonoceps occipitalis) (19%). Mortality rates recorded and inferred from telemetry suggested that poisoning is prevalent. However, only 6 mortalities of the 26 presumed mortalities were confirmed to be caused by poisoning, highlighting the challenges of determining the cause of death when working across large landscapes. Despite declines, our data provide evidence that southern Tanzania has higher current encounter rates of African vultures than elsewhere in East Africa. Preventing further declines will depend greatly on mitigating poisoning. Based on our results, we suggest that the use of multiple techniques improves understanding of population trends over the short term. [ABSTRACT FROM AUTHOR]

The main goals of this research are to determine the developmental tendency of salmonellosis in the Republic of North Macedonia and to determine the index of dynamics and the rate of decline/increase of salmonellosis in the Republic of North Macedonia. The research covers the period from 01.01.2012 until 31.12.2022. The data used to implement this study were obtained from the Institute of Public Health of the Republic of North Macedonia. The research included 2711 subjects who were sick with salmonellosis from 2012 to 2022. The following statistical methods of work are used: linear trend, dynamic index with a constant base, dynamic index with a variable base (chain index), rate of decline, and rate of increase. The results of the study suggest that in the period 2012-2022, the highest number of patients (n=373) and the highest incidence (18/100000) of salmonellosis were registered in 2018, and the lowest in 2020 (n=119, I=5.8/100000). From the linear trend values, it can be concluded that salmonellosis in the Republic of North Macedonia shows a decreasing tendency. The biggest increase in salmonellosis in the Republic of North Macedonia was in 2015 by 71% compared to 2014. The biggest decrease in salmonellosis in the Republic of North Macedonia was in 2020 by 48% compared to 2019. From the study, it can be concluded that food operators and manufacturers are observing the procedures of the HACCP control system for food safety, leading to a possible decrease in salmonellosis. [ABSTRACT FROM AUTHOR]

Abstract Background Mucopolysaccharidosis (MPS) II is a rare, X-linked lysosomal storage disease. Approximately two-thirds of patients have central nervous system involvement with some demonstrating progressive cognitive impairment (neuronopathic disease). The natural history of cognitive and adaptive function in patients with MPS II is not well-defined. This 2-year, prospective, observational study evaluated the neurodevelopmental trajectories of boys with MPS II aged ≥ 2 years and 70); between-group differences were nonsignificant. No clear subgroups or patterns were identified for individual changes in VABS-II ABC scores. In total, 49 patients (89.1%) reported ≥ 1 adverse event (AE) and nine patients (16.4%) reported serious AEs. Conclusions Some patients with MPS II had rapid declines in cognitive ability, whereas others remained relatively stable after an initial decline. These insights provide a basis for more detailed analyses of different patient subgroups, which may enhance the definition and understanding of factors that influence cognitive and adaptive function in MPS II. Trial registration ClinicalTrials.gov, NCT01822184. Registered retrospectively: April 2, 2013.

The economic, technological, social, and political development of Russia is affected by unfavorable external circumstances. The purpose of the article is to reveal the features of the external environment uncertainty, assess its impact on the economic systems of the Russian regions, and to propose a mechanism of adaptation to future recessionary phenomena. The article uses methods of analysis and synthesis, induction and deduction, comparison, economic analysis; a systematic approach. The authors present the results of comparative analysis of Russian regions’ development indicators in 2019–2021 and 2022. It is determined that the speed and effectiveness of overcoming uncertainty factors depends on the adaptive abilities of Russian regions and the speed of decision-making. The key directions of state policy measures to maintain the stability of the economic systems of the regions are substantiated.

Alder yellows (ALY) phytoplasma (16SrV-C) is associated with ALY, a disease of several Alnus (alder) species in Europe and A. rubra in North America. In all affected species, the symptoms are similar. However, latent infections are common. ALY phytoplasma includes different strains which may be occasionally transmitted to grapevines leading to some grapevine yellows diseases. In the current study, visual symptom assessment and PCR-based methods using universal and group-specific phytoplasma primers were used to update and extend knowledge on the occurrence, impact, and genetic diversity of ALY phytoplasma in declining and non-symptomatic A. glutinosa and A. cordata trees in the Basilicata and Campania regions of southern Italy. ALY phytoplasma was detected in 80% of alder trees examined. In symptomatic trees, no other cause of disease was observed. More than half of alder trees that tested phytoplasma-positive proved to be latently infected. A considerable genetic variability was observed among the newly recorded ALY phytoplasma strains in southern Italy in almost of the genes examined. These included 16S rRNA, 16S/23S rDNA spacer region, ribosomal protein rpsV (rpl22) and rpsC (rps3), map, imp, and groEL genes. Eleven new genotypes were identified at map gene sequence level. However, the genetic differences observed were not related to plant host species, geographical origin, and symptoms shown by infected alder trees. Also, this study indicates that ALY phytoplasma is more widespread than previously thought.

Extended Abstract Introduction and Objective: The forests of Zagros, as the most extensive and at the same time as the most damaged forests of the country, have been affected by the extensive decline of oak trees in recent years, and in this sense, they are in a critical conditions. Decline of oak trees is described as a wide and complex phenomenon that causes a decrease in growth and physiological weakness followed by the attack of pathogenic agents. As sustainability of these forests is now facing a serious problem, proper management strategies are required to deal with the decline phenomenon, before these valuable ecosystems are completely destroyed. The implementation of such strategies necessitates collecting basic information, including map of the decline distribution and the extent of the lost biomass of trees as a result of decay. The purpose of this study is to estimate the amount of biomass on the above-ground in dead oak trees as a result of the decline of Zagros forests, which was carried out in the forests of Dadabad region of Lorestan province. Material and Methods: The present study was conducted in Dadabad forests located in the southwest of Khorramabad, Lorestan, Iran. To achieve this purpose, 40 dried trees were randomly selected and biometric parameters including diameter at knee height, diameter at breast height, as well as height and crown diameter were measured. Different parts of the tree were fragmented, dried, and weighed. Using regression analysis, the biomass of different parts was modeled against the independent variables of diameter at knee height, diameter at breast height, crown height, and diameter. Finally, at the area of 32 hectares of the forest stand, a 100% inventory was conducted, and different characteristics of all Iranian oak trees were measured. Results: The results of the research declared that strong relationships can be established to estimate the biomass of Iranian oak trees. The result of fitting linear and non-linear models to estimate the biomass of this tree species showed that if the average diameter of the tree crown was used as an independent variable, the more suitable model was the power model with an explanation coefficient of 0.857. Also, the validity results of the model or the value of RMSE% for the obtained equation was 9.082%. The total biomass in the study area was 389.994 tons, of which 39.54%, i.e. 154.226 tons, of the area's biomass was lost under decline phenomenon. Conclusion: The results indicated that in the comparison between linear and non-linear regression models, the best model for estimating the biomass of this species was the power model based on the average diameter of the crown with R2=0.857. In general, using the average diameter of the crown as an estimator variable for the Iranian oak species can suggest a better and more appropriate assessment of the above-ground biomass of these trees.

Abstract Background Pre-Exposure Prophylaxis (PrEP) has demonstrated clinical efficacy in preventing HIV infection, yet its uptake remains low. This study, conducted in five PrEP implementing districts in Lesotho, examined factors motivating persons at risk of HIV infection to adopt or reject PrEP when offered freely. Methods In-depth interviews were undertaken with stakeholders directly engaged with PrEP policy (n = 5), program implementation (n = 4), and use (current PrEP users = 55, former PrEP users = 36, and PrEP decliners (n = 6)). Focus group discussions (n = 11, 105 total participants) were conducted with health staff directly providing HIV and PrEP services. Results Demand for PrEP was reported highest among those at greatest risk for HIV acquisition: those in serodiscordant relationships and/or engaged in sex work. Culturally sensitive PrEP counseling was described as an opportunity to transfer knowledge, build trust, and address user concerns. Conversely, top-down counseling resulted in PrEP distrust and confusion about HIV status. Key motivations for PrEP uptake revolved around sustaining core social relationships, desire for safer conception, and caring for ailing relatives. The decline of PrEP initiation was driven by a combination of individual-level factors (risk perception, perceived side effects, disbelief of the drug’s efficacy and PrEP’s daily pill regimen), societal factors (lack of social support and HIV-related stigma), and structural factors related to PrEP access. Conclusions Our findings suggest strategies for effective national PrEP rollout and implementation include: (1) demand creation campaigns which highlight positive aspects of PrEP, while simultaneously addressing apprehensions for uptake; (2) strengthening health provider counseling capacity; and (3) addressing societal and structural HIV-related stigma.

The article puts Elizabeth II's travels into perspective, in a world of declining British influence. The trend is clear: apart from trips to European countries (notably France and Germany), the most trips were made to countries where the Queen was sovereign until the end, notably Canada (22 trips) and Australia (15 trips) and the Caribbean and Pacific islands that remained under British sovereignty. Then, in descending order, to Commonwealth countries, with a preference for those where she remained Sovereign