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Peru has a great potential for forestry plantations, nevertheless, importations of this type of products are getting very expensive. Soils under forest are acidic and infertile to support sustainable economically valuable forest tree species such as teak. Information is lacking on proper fertility management in forest plantations such as teak. Therefore, the objective of this study was to explore the effect of lime, and organic and inorganic fertilizers on the early growth and nutrient composition of 12-month old teak grown on acidic soil of Peru. The soil under field study was acidic with a pH of 4.99, low in fertility. A factorial design of 2x3: Lime (No Lime and Liming) and fertilizer (organic, inorganic and mixture), with 9 repetitions was adopted. Tree biometric parameters (height, diameter, biomass) and N, P, K, Ca, Mg, Fe, Cu, Mn, Zn foliar concentrations were determined during early the growth of teak. Treatments with addition of dolomite lime favored higher biometric parameters, and use of organic fertilizers promoted more growth than inorganic fertilizers. In the case of nutrients, no major differences were observed between limed and unlimed treatments while organic fertilizer promoted Ca, K and S nutrition. The results show that the application of lime and organic fertilizers is essential for the successful management and establishment of teak plants in acidic soils of Peru. [ABSTRACT FROM AUTHOR]

Perindopril is a long-acting, once-daily lipophilic angiotensin-converting enzyme inhibitor with high tissue angiotensin-converting enzyme affinity, lowering angiotensin II and potentiating bradykinin. Its efficacy, safety, and tolerability are well established in the treatment of hypertension and heart failure. Moreover, large morbidity–mortality trials, such as the EUropean trial on Reduction Of cardiac events with Perindopril in stable coronary Artery disease (EUROPA) and Perindopril pROtection aGainst REcurrent Stroke Study (PROGRESS), have shown that antihypertensive treatment with perindopril reduces and prevents cardiovascular disease in a large range of patients with vascular diseases, whether or not they are hypertensive. Thus, the outcomes of these and other trials support the concept of cardiovascular protective properties of angiotensin-converting enzyme inhibition with perindopril in addition to the obvious blood-pressure–lowering effect. Considering its properties and the clinical evidence on efficacy and tolerability that has been gathered, perindopril fulfils the criteria of the latest guidelines for hypertension and cardiovascular disease management and should therefore be considered as a first-line antihypertensive agent, forming a consistent part of the comprehensive strategy against hypertension and related cardiovascular complications. [Copyright &y& Elsevier]

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Reports on the effects of single and multiple doses of methimazole on serum thyroxine and heart rate in hyperthyroid patients. Advantages of using single over divided dose of an antithyroid drug; Preference of methimazole to propylthiouracil; Dependence of antithyroid effectiveness of the thionamides on their ability to inhibit the organification of iodine; Percholrate discharge test to evaluate the degree of inhibition.

Abstract: Congenital galactosaemia reveals usually in the second and third weeks of life with a severe liver dysfunction. We report on a case of congenital galactosaemia with, on the one hand, an early onset liver failure, without any free interval, and on the other hand, an hemophagocytic syndrome as a severe secondary outbreak with pulmonary haemorrhage. Appropriate diet led to normalisation of liver function. Hemophagocytosis, probably linked to an associated Klebsiella Pneumoniae sepsis, had a favourable outcome after antibiotic and corticosteroid therapy. [Copyright &y& Elsevier]