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The need to sustain data and outputs from research projects well beyond their initial grant-funded period is commonplace within academia, particularly so within the Humanities. We often find that these semi-active or warm data collections have value and require care beyond the life of the original hosting, system, or platform they were conceived upon. With the increasing demand to make data more open, and research funding bodies increasing requirements and time periods for which research data must remain available, institutions need to be ready to offer researchers the tools and platforms to comply. Compliance is one lens to view this particular challenge through, the other is that institutions should also be motivated by celebrating the research they develop, and the continued scholarly benefits and impact gained through being hosted and shared for as long as possible. This paper offers a practical insight into the methods being employed at the University of Oxford to support digital humanities scholars (and others) safeguard their digital legacy for future generations. [ABSTRACT FROM AUTHOR]

Heart and lung interaction within the thoracic cavity is well known during inhalation and exhalation, both spontaneously and during mechanical ventilation. Disease and dysfunction of one organ affect the function of the other. A review of the cause-and-effect relationship between cardiovascular disease and acute respiratory distress syndrome (ARDS) is of significance, as the disease burden of both conditions has both a national and global impact on health care. This literature review examines the relationship between cardiovascular disease and ARDS over the past 25 years. [ABSTRACT FROM AUTHOR]

Background: Computer-based cognitive rehabilitation programs may help adolescent and young adult (AYA) patients with cancer-related cognitive impairment. This pilot study investigated the feasibility of cognitive rehabilitation as a preventive intervention for AYA patients receiving chemotherapy. Explorative objectives included the correlation of cognitive performance with serum brain-derived neurotrophic factor (BDNF). Methods: This pilot prospective study included English-speaking patients 12–25 years of age with a fist diagnosis of cancer requiring chemotherapy. Participants enrolled in the intervention arm participated in a computer-based neurocognitive training program for 20–30 minutes daily for 16 weeks. Outcome measures, including engagement with and completion of computerized neurocognitive testing and serum BDNF levels, were obtained within the first month following diagnosis, ∼16 and 24 weeks from enrollment. Results: Fourteen of 18 eligible patients provided consent, with 7 patients assigned to each the intervention arm and nonintervention arm. Seventy-one percent of the patients in the intervention arm completed at least 80% of the required activities. Compared to baseline, patients in the nonintervention arm demonstrated higher prevalence of impairment in four of the six cognitive domains (processing speed, visual attention, attention/working memory, and executive function) at the end of the study period. There was a nonstatistically significant reduction of serum BDNF levels over time, which was observed in both intervention and nonintervention arms. Conclusion: This pilot study provides some evidence that it is feasible for AYAs with new cancer diagnoses to receive standardized cognitive rehabilitation. Patients receiving cognitive activities experienced less impairment in numerous cognitive domains. [ABSTRACT FROM AUTHOR]