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Optimizin the efficient light‐trapping in the photothermal conversion by enhancing localized surface plasmon resonance (LSPR) is crucial in improving light‐heat‐conversion efficiency of Ti3C2Tx MXene. However, its susceptibility to oxidation makes it prone to oxides formation, diminishing its metallic properties and significantly reducing the LSPR effect. This work synthesizes a kind of air‐stable hybrid Ti3C2Tx MXenes by a synergistic densification strategy that incorporates sulfhydryl‐bonding between organic and inorganic parts by reacting Ti3C2Tx MXene with thiocarboxylic acids. The resultant shortening of electron transport pathways, enhanced charge density, and the generation of additional electronic states around the Fermi level collectively contribute to an augmented LSPR effect. Additionally, the hybrid Ti3C2Tx MXenes also demonstrate high‐temperature resistance and reduced water interactions. These combined effects substantially elevate photothermal conversion efficiency through thiocarboxylic acids modification, reaching a photothermal evaporation rate of 1.77 kg m−2 h−1 with 94.56% efficiency in hybrid Ti3C2Tx MXenes. The approach paves the way for the design and development of a three‐in‐one strategy for photothermal conversion. [ABSTRACT FROM AUTHOR]

By adopting the Takagi–Sugeno (T‐S) fuzzy theory, this paper focuses on the adaptive control of fractional‐order time‐delay systems involving unknown parameters and input saturations. T‐S fuzzy systems with "IF‐THEN" rules are employed to describe fractional‐order nonlinear systems. The influence of input saturation is handled by designing an auxiliary system. By using a norm conversion, the system's time‐delay term is converted into a non‐delayed form. Adaptive updating rules are devised to evaluate uncertainties of the system, and a new control approach is proposed. The devised controller can not only guarantee the boundedness of variables involved but also make state variables converge into a sufficiently small neighborhood of the origin, even in the presence of uncertainties, saturation functions, and system parameters. Finally, numerical studies are given to verify the correctness of the designed scheme. [ABSTRACT FROM AUTHOR]

Microwave absorbers with ultra-broad bandwidths are extremely effective in combating the wide range of electromagnetic pollution and radar detection. However, the conventional magnetoelectric compositing techniques for achieving a wide absorption bandwidth suffer from drawbacks of a complex preparation process and low yield production. A single-phased microwave absorber is an ideal choice for large-scale application while integrating desired levels of dielectric loss and a broad magnetic loss continues to pose a significant challenge. In this work, an ultra-broad single-phase microwave absorber is developed by abating the doping competition of dual high-valence Zr4+ and Ti4+ ions in the M-type barium ferrite. Due to the disparities in electronegativity and ionic radii of Zr4+ and Ti4+ ions, enhanced incorporation of high-valence ions substituting for Fe3+ ions in Zr4+–Ti4+ ion co-doped systems to simultaneously improve the complex permittivity and generate multi-resonance permeability. First-principles calculations and magnetic resonance peak-differentiating and imitating results show that the enhanced electromagnetic properties stem from the optimized electronic structure and strengthened exchange coupling effect. By optimizing the dopant Zr4+ and Ti4+ contents in terms of composition of BaFe12−2xZrxTixO19 with x = 0.4, an ultra-broad bandwidth of 16.3+ GHz and an ultra-strong absorption intensity of up to −54.8 dB have been successfully achieved at a very thin matching thickness down to ∼1.08 mm, much superior to those of the existing various types of state-of-the-art microwave absorbers. Therefore, this material shows great application potentials as preeminent microwave absorbers with unprecedented comprehensive performance. [ABSTRACT FROM AUTHOR]

It is debated whether carbohydrate restriction has metabolic advantage for its variable weight loss. Five-week-old male mice fed a high-fat diet and receiving a glycolytic inhibitor, 2-deoxyglucose, died within 9 days. They exhibited greater decreases in rectal temperature, appetite, and decline in body weight accompanied by increasing total cholesterol level than the other groups. This study suggests that carbohydrate is necessary for adequate physical and metabolic performance when lipid-rich diet is loaded. [ABSTRACT FROM AUTHOR]

Background: The roles of microRNAs (miRNAs) in osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) remain largely unexplored. In this study, the underlying molecular mechanism of osteogenic differentiation in hPDLSCs is investigated using miRNA profiling.Methods: The miRNA expression profile during osteogenic differentiation was analyzed using a microarray. Target genes of miRNAs with at least two-fold change in expression (P <0.05) were predicted by bioinformatics. Six miRNAs with osteogenesis-related target genes were validated by quantitative reverse transcription-polymerase chain reaction (qRT-PCR).Results: Expression of 116 miRNAs was found to be altered after osteoinduction, with 30 upregulated and 86 downregulated. Thirty-one of these miRNAs (26.7%) had osteogenesis-related target genes. Changes in expression levels of six of the 31 miRNAs (miR-654-3p, miR-4288, miR-34c-5p, miR-218-5p, miR-663a, and miR-874-3p) were validated by qRT-PCR.Conclusions: Significant alterations in miRNA expression profiles were observed during osteogenic differentiation of hPDLSCs. These results imply that miRNAs may have regulatory effects on this process by targeting osteogenesis-related genes. [ABSTRACT FROM AUTHOR]

Background: Long non-coding RNAs (lncRNAs) are emerging as important regulators of eukaryotic gene expression and have been shown to regulate various modular components of development and differentiation. However, the roles of lncRNAs in the regulation of osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) remain poorly understood.Methods: Expression patterns of lncRNA and messenger RNA (mRNA) during osteogenic differentiation were profiled using microarray analysis. Quantitative reverse transcription polymerase chain reaction was performed to validate the microarray data. Biologic functions of candidates were revealed by: 1) cluster analysis; 2) gene ontology (GO); and 3) pathway analysis. Coding-non-coding gene coexpression (CNC) networks were constructed to investigate potential regulatory roles of lncRNAs and osteogenesis-related mRNAs.Results: After osteoinduction, 3,557 mRNAs and 2,171 lncRNAs were differentially expressed, of which 994 lncRNAs were upregulated and 1,177 were downregulated (fold change >2.0 or <-2.0; P <0.05). Cluster analysis showed that lncRNAs and mRNAs from the experimental and control groups belonged to different clusters. GO analysis demonstrated that: 1) cellular process; 2) biologic regulation; and 3) regulation of biologic process were the most significant groups related to induction. Pathway analysis indicated that 83 pathways corresponded to differentially expressed mRNAs, including: 1) mitogen-activated protein kinase; 2) vascular endothelial growth factor; and 3) transforming growth factor-β signaling pathways. CNC network analysis indicated that 393 lncRNAs were closely related to osteogenesis-related mRNAs.Conclusions: Expression profiles of lncRNAs and mRNAs were significantly altered during osteogenic differentiation of hPDLSCs. This result suggests that lncRNAs may play crucial roles in this process and could regulate mRNA expression. [ABSTRACT FROM AUTHOR]

Circulating and myocardial expressions of receptor activator of nuclear factor-κb ligand and osteoprotegerin are activated in heart failure; however, it remains to be determined their pathophysiological roles on left ventricular structure and function in interaction with renin-angiotensin system. We conducted experiments using 8-week-old osteoprotegerin(-/-) mice and receptor activator of nuclear factor-κb ligand-transgenic mice to assess whether they affect the angiotensin II-induced left ventricular remodeling. Subcutaneous infusion of angiotensin II to osteoprotegerin(-/-) mice progressed the eccentric hypertrophy, resulting in left ventricular systolic dysfunction for 28 days, and this was comparable with wild-type mice, showing concentric hypertrophy, irrespective of equivalent elevation of systolic blood pressure. The structural alteration was associated with reduced interstitial fibrosis, decreased procollagen α1 and syndecan-1 expressions, and the increased number of apoptotic cells in the left ventricle, compared with wild-type mice. In contrast, angiotensin II infusion to the receptor activator of nuclear factor-κb ligand-transgenic mice revealed the concentric hypertrophy with preserved systolic contractile function. Intraperitoneal administration of human recombinant osteoprotegerin, but not subcutaneous injection of anti-receptor activator of nuclear factor-κb ligand antibody, to the angiotensin II-infused osteoprotegerin(-/-) mice for 28 days ameliorated the progression of heart failure without affecting systolic blood pressure. These results underscore the biological activity of osteoprotegerin in preserving myocardial structure and function during the angiotensin II-induced cardiac hypertrophy, independent of receptor activator of nuclear factor-κb ligand activity. In addition, the antiapoptotic and profibrotic actions of osteoprotegerin that emerged from our data might be involved in the mechanisms. [ABSTRACT FROM AUTHOR]