147 results on '"Hartmann-Petersen, Rasmus"'
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2. Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants
3. Characterizing glucokinase variant mechanisms using a multiplexed abundance assay
4. A mutational atlas for Parkin proteostasis
5. Discovering functionally important sites in proteins
6. A comprehensive map of human glucokinase variant activity
7. The moonlighting of RAD23 in DNA repair and protein degradation
8. Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components
9. Prediction of Quality-control Degradation Signals in Yeast Proteins
10. 14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes
11. Disease-linked mutations cause exposure of a protein quality control degron
12. HSP70-binding motifs function as protein quality control degrons
13. Conserved degronome features governing quality control associated proteolysis
14. A context-dependent and disordered ubiquitin-binding motif
15. Novel HARS2 missense variants identified in individuals with sensorineural hearing impairment and Perrault syndrome
16. Biophysical and Mechanistic Models for Disease-Causing Protein Variants
17. Destabilization and Degradation of a Disease-Linked PGM1 Protein Variant.
18. Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function
19. The exocyst subunit Sec3 is regulated by a protein quality control pathway
20. Polyglutamine expansion of ataxin-3 alters its degree of ubiquitination and phosphorylation at specific sites
21. Cellular and molecular mechanisms of aspartoacylase and its role in Canavan disease.
22. UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1
23. DSS1/Sem1, a Multifunctional and Intrinsically Disordered Protein
24. Water dynamics in MCF-7 breast cancer cells: a neutron scattering descriptive study
25. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast
26. Phosphorylation of Schizosaccharomyces pombe Dss1 mediates direct binding to the ubiquitin‐ligase Dma1 in vitro.
27. Regulation of NF-κB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13)
28. A Luminal Flavoprotein in Endoplasmic Reticulum-Associated Degradation
29. Herp Regulates Hrd1-mediated Ubiquitylation in a Ubiquitin-like Domain-dependent Manner
30. Rare Catechol‑O‑methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets.
31. Lynch syndrome, molecular mechanisms and variant classification.
32. The 20S Proteasome as an Assembly Platform for the 19S Regulatory Complex
33. Thioredoxin Txnl1/TRP32 Is a Redox-active Cofactor of the 26 S Proteasome
34. New ATPase regulators—p97 goes to the PUB
35. How phosphorylation impacts intrinsically disordered proteins and their function.
36. Ubxd1 is a novel co-factor of the human p97 ATPase
37. Mammalian 26S Proteasomes Remain Intact during Protein Degradation
38. Deciphering the Alphabet of Disorder—Glu and Asp Act Differently on Local but Not Global Properties.
39. Characterisation of the nascent polypeptide-associated complex in fission yeast
40. Adrm1, a Putative Cell Adhesion Regulating Protein, is a Novel Proteasome-associated Factor
41. Molecular chaperones in targeting misfolded proteins for ubiquitin-dependent degradation
42. Quantifying Protein–Protein Interactions in the Ubiquitin Pathway by Surface Plasmon Resonance
43. Protein Degradation: Recognition of Ubiquitinylated Substrates
44. Integral UBL domain proteins: a family of proteasome interacting proteins
45. Uch2/Uch37 is the Major Deubiquitinating Enzyme Associated with the 26 S Proteasome in Fission Yeast
46. Interaction of the Anaphase-promoting Complex/Cyclosome and Proteasome Protein Complexes with Multiubiquitin Chain-binding Proteins
47. Ubiquitin binding proteins protect ubiquitin conjugates from disassembly
48. UBA domain containing proteins in fission yeast
49. Transferring substrates to the 26S proteasome
50. The disordered PCI‐binding human proteins CSNAP and DSS1 have diverged in structure and function.
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