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Emerging applications of biotechnology such as new genomic techniques may give rise to new uncertainties and uncertain risks. Particularly the increased complexity and limited knowledge of possible risks associated with these new techniques, make it currently impossible to perform an adequate environmental risk assessment. As a result, there is a risk that such techniques don’t get beyond experiments demonstrating the proof of principle, stifling their further development and implementation. To break free from this deadlock, we must be able to learn what such uncertainties and uncertain risks entail, and how they should be assessed to ensure safe further development. To shape a responsible learning environment to explore uncertainties and uncertain risks, we have organized five stakeholder workshops. By means of a case about the genetic engineering of plants’ rhizosphere–an application abundant with uncertain risks–we identified tensions between different stakeholder groups and their different estimates of uncertainties and uncertain risks. Based upon derived insights, we developed a tool–a script for researchers to organize a stakeholder workshop–that enables a constructive discussion about emerging risks with a broad range of stakeholders. Thereby, the script provides a step-by-step approach to identify uncertainties, develop anticipatory strategies and adaptations in (experimental) research designs to lower or mitigate the earlier identified uncertainties, and helps to identify knowledge gaps for which (additional) risk research should be set up.

Hydraulic engineering infrastructure is supposed to keep functioning for many years and is likely to interfere with both the natural and the social environment at various scales. Due to its long life-cycle, hydraulic infrastructure is bound to face changing environmental conditions as well as changes in societal views on acceptable solutions. This implies that sustainability and adaptability are/should be important attributes of the design, the development and operation of hydraulic engineering infrastructure. Sustainability and adaptability are central to the Building with Nature (BwN) approach. Although nature-based design philosophies, such as BwN, have found broad support, a key issue that inhibits a wider mainstream implementation is the lack of a method to objectify BwN concepts. With objectifying, we mean turning the implicit into an explicit engineerable ‘object’, on the one hand, and specifying clear design ‘objectives’, on the other. This paper proposes the “Frame of Reference” approach as a method to systematically transform BwN concepts into functionally specified engineering designs. It aids the rationalisation of BwN concepts and facilitates the transfer of crucial information between project development phases, which benefits the uptake, acceptance and eventually the successful realisation of BwN solutions. It includes an iterative approach that is well suited for assessing status changes of naturally dynamic living building blocks of BwN solutions. The applicability of the approach is shown for a case that has been realised in the Netherlands. Although the example is Dutch, the method, as such, is generically applicable.

By definition, Building with Nature solutions utilise services provided by the natural system and/or provide new opportunities to that system. As a consequence, such solutions are sensitive to the status of, and interact with the surrounding system. A thorough understanding of the ambient natural system is therefore necessary to meet the required specifications and to realise the potential interactions with that system. In order to be adopted beyond the pilot scale, the potential impact of multiple BwN solutions on the natural and societal systems of a region need to be established. This requires a ‘reality check’ of the effectiveness of multiple, regional-scale applications in terms of social and environmental costs and benefits. Reality checking will help establish the upscaling potential of a certain BwN measure when addressing a larger-scale issue. Conversely, it might reveal to what extent specific smaller-scale measures are suitable in light of larger regional-scale issues. This paper presents a stepwise method to approach a reality check on BwN solutions, based on the Frame of Reference method described in a companion paper (de Vries et al., 2020), and illustrates its use by two example cases. The examples show that a successful pilot project is not always a guarantee of wider applicability and that a broader application may involve dilemmas concerning environment, policy and legislation.