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Your search keyword '"Interdisciplinary Center Herzliya (IDC)"' showing total 2 results
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2 results on '"Interdisciplinary Center Herzliya (IDC)"'

1. Leader-based de-anonymization of an anonymous read/write memory

Author

Michel Raynal, Emmanuel Godard, Gadi Taubenfeld, Damien Imbs, Laboratoire d'Informatique et Systèmes (LIS), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), the World Is Distributed Exploring the tension between scale and coordination (WIDE), Inria Rennes – Bretagne Atlantique, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-SYSTÈMES LARGE ÉCHELLE (IRISA-D1), Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Interdisciplinary Center Herzliya (IDC), 16-CE40-0023-03, Agence Nationale de la Recherche, ANR-16-CE40-0023,DESCARTES,Abstraction modulaire pour le calcul distribué(2016), Université de Bretagne Sud (UBS)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National de Recherche en Informatique et en Automatique (Inria)-École normale supérieure - Rennes (ENS Rennes)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-CentraleSupélec-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Bretagne Sud (UBS)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), and Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-École normale supérieure - Rennes (ENS Rennes)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1)

Subjects
Register (sociolinguistics), General Computer Science, De-anonymization, Computer science, [INFO.INFO-CE]Computer Science [cs]/Computational Engineering, Finance, and Science [cs.CE], Concurrent algorithm, 020207 software engineering, 0102 computer and information sciences, 02 engineering and technology, 01 natural sciences, Theoretical Computer Science, Read-write memory, Shared memory, 010201 computation theory & mathematics, Synchronization (computer science), 0202 electrical engineering, electronic engineering, information engineering, Mutual exclusion, Arithmetic, Impossibility, Hardware_REGISTER-TRANSFER-LEVELIMPLEMENTATION, ComputingMilieux_MISCELLANEOUS
Abstract

Anonymous shared memory is a memory in which processes use different names for the same shared read/write register. As an example, a shared register named A by a process p and a shared register named B by another process q can correspond to the very same register X, and similarly for the names B at p and A at q which can correspond to the same register \(Y\ne X\). Hence, there is a permanent disagreement on the register names among the processes. This new notion of anonymity was recently introduced by G. Taubenfeld (PODC 2017), who presented several memory-anonymous algorithms and impossibility results.

Published
2020
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2. Transient blood–brain barrier disruption is induced by low pulsed electrical fields in vitro: an analysis of permeability and trans-endothelial electric resistivity

Author

David Guez, Orly Ravid, Lucie Dehouck, Dana Atrakchi, Itzik Cooper, Chen Shemesh, Yael Mardor, Shirley Sharabi, Fabien Gosselet, Yael Bresler, Michal Schnaider-Beeri, Dianne Daniels, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University [Tel Aviv], Icahn School of Medicine at Mount Sinai [New York] (MSSM), Laboratoire de la Barrière Hémato-Encéphalique (LBHE), Université d'Artois (UA), and Interdisciplinary Center Herzliya (IDC)

Subjects
electroporation, [SDV]Life Sciences [q-bio], Pharmaceutical Science, pulsed electrical fields, Blood–brain barrier, Models, Biological, Capillary Permeability, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Lactate dehydrogenase, Electric Impedance, medicine, Animals, Humans, Transcellular, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Tight junction, Chemistry, Electroporation, lcsh:RM1-950, Endothelial Cells, in vitro, General Medicine, trans-endothelial electric resistivity, Coculture Techniques, In vitro, lcsh:Therapeutics. Pharmacology, medicine.anatomical_structure, Blood-Brain Barrier, Permeability (electromagnetism), Paracellular transport, Biophysics, Cattle, Endothelium, Vascular, permeability, Pericytes, 030217 neurology & neurosurgery, Research Article
Abstract

International audience; The blood-brain barrier (BBB) is limiting transcellular and paracellular movement of molecules and cells, controls molecular traffic, and keeps out toxins. However, this protective function is the major hurdle for treating brain diseases such as brain tumors, Parkinson's disease, Alzheimer's disease, etc. It was previously demonstrated that high pulsed electrical fields (PEFs) can disrupt the BBB by inducing electroporation (EP) which increases the permeability of the transcellular route. Our goal was to study the effects of low PEFs, well below the threshold of EP on the integrity and function of the BBB. Ten low voltage pulses (5-100 V) were applied to a human in vitro BBB model. Changes in permeability to small molecules (NaF) were studied as well as changes in impedance spectrum and trans-endothelial electric resistivity. Viability and EP were evaluated by Presto-Blue and endogenous Lactate dehydrogenase release assays. The effect on tight junction and adherent junction protein was also studied. The results of low voltage experiments were compared to high voltage experiments (200-1400 V). A significant increase in permeability was found at voltages as low as 10 V despite EP only occurring from 100 V. The changes in permeability as a function of applied voltage were fitted to an inverse-exponential function, suggesting a plateau effect. Staining of VE-cadherin showed specific changes in protein expression. The results indicate that low PEFs can transiently disrupt the BBB by affecting the paracellular route, although the mechanism remains unclear.

Published
2019
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