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Your search keyword '"Jurgen M.R. Ligthart"' showing total 5 results
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5 results on '"Jurgen M.R. Ligthart"'

1. Comparison of diagnostic accuracy measures of novel 3D quantitative coronary angiography based software and diastolic pressure ratio for fractional flow Reserve. A single center pooled analysis of FAST EXTEND and FAST II studies

Author

Alessandra Scoccia, Tara Neleman, Mariusz Tomaniak, Kaneshka Masdjedi, Frederik T.W. Groenland, Isabella Kardys, Jurgen M.R. Ligthart, Nicolas M. Van Mieghem, Ernest Spitzer, and Joost Daemen

Subjects
Coronary physiology, dPR, NHPR, FFR, Fractional flow reserve, vFFR, Diseases of the circulatory (Cardiovascular) system, RC666-701
Published
2022
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2. IgM anti-malondialdehyde low density lipoprotein antibody levels indicate coronary heart disease and necrotic core characteristics in the Nordic Diltiazem (NORDIL) study and the Integrated Imaging and Biomarker Study 3 (IBIS-3)Research in Context

Author

Victor J. van den Berg, Dorian O. Haskard, Artur Fedorowski, Adam Hartley, Isabella Kardys, Mikhail Caga-Anan, K. Martijn Akkerhuis, Rohit M. Oemrawsingh, Robert Jan van Geuns, Peter de Jaegere, Nicolas van Mieghem, Evelyn Regar, Jurgen M.R. Ligthart, Victor A.W.M. Umans, Patrick W. Serruys, Olle Melander, Eric Boersma, and Ramzi Y. Khamis

Subjects
Medicine, Medicine (General), R5-920
Abstract

Background: Certain immunoglobulins (Ig) are proposed to have protective functions in atherosclerosis. Objectives: We tested whether serum levels of IgG and IgM autoantibodies against malondialdehyde low density lipoprotein (MDA-LDL) are associated with clinical coronary heart disease (CHD) and unfavorable plaque characteristics. Methods: NORDIL was a prospective study investigating adverse cardiovascular outcomes in hypertensive patients. IBIS-3 analyzed lesions in a non-culprit coronary artery with

Published
2018
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3. Serial Coronary Imaging of Early Atherosclerosis Development in Fast-Food-Fed Diabetic and Nondiabetic Swine

Author

Nienke S. van Ditzhuijzen, MSc, Mieke van den Heuvel, MD, Oana Sorop, PhD, Alexia Rossi, MD, PhD, Timothy Veldhof, MSc, Nico Bruining, PhD, Stefan Roest, BSc, Jurgen M.R. Ligthart, RT, Karen Th. Witberg, CCRN, Marcel L. Dijkshoorn, BSc, Koen Nieman, MD, PhD, Monique T. Mulder, PhD, Felix Zijlstra, MD, PhD, Dirk J. Duncker, MD, PhD, Heleen M.M. van Beusekom, PhD, and Evelyn Regar, MD, PhD

Subjects
animal model, coronary artery disease, coronary computed tomography angiography, diabetes mellitus, near-infrared spectroscopy, optical coherence tomography, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Patients with diabetes mellitus (DM) are at increased risk for atherosclerosis-related events compared to non-DM (NDM) patients. With an expected worldwide epidemic of DM, early detection of anatomic and functional coronary atherosclerotic changes is gaining attention. To improve our understanding of early atherosclerosis development, we studied a swine model that gradually developed coronary atherosclerosis. Interestingly, optical coherence tomography, near-infrared spectroscopy (NIRS), vascular function, and histology demonstrated no differences between development of early atherosclerosis in fast-food-fed (FF) DM swine and that in FF-NDM swine. Coronary computed tomography angiography did not detect early atherosclerosis, but optical coherence tomography and near-infrared spectroscopy demonstrated coronary atherosclerosis development in FF-DM and FF-NDM swine.

Published
2016
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