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Through this paper, we call for a distributed, Internet- based collaboration to address one of the worst plagues of our present world, malaria. The spirit is a nonproprietary peer- production of information-embedding goods. And we propose to use the grid technology to enable such a worldwide "open- source" like collaboration. The first step toward this vision has been achieved during the summer 2005 on the enabling grids for E-scienceE (EGEE) grid infrastructure where 42 million ligands were docked for a total amount of 80 CPU years in 6 weeks in the quest for new drugs. The impact of this first deployment has significantly raised the interest of the research community so that several laboratories all around the world expressed interest to propose targets for a second large-scale deployment against malaria. [ABSTRACT FROM AUTHOR]