451 results on '"Krishnamurthy, Sairam"'
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2. Inhibition of phosphodiesterase-4 mitigates stress-re-stress-paradigm induced mitochondrial perturbations in rats exhibiting PTSD-like symptoms
3. Diet and Nutraceuticals for treatment and prevention of primary and secondary stroke: Emphasis on nutritional antiplatelet and antithrombotic agents
4. Rhodanine composite fluorescence probes to detect pathological hallmarks in Alzheimer's disease models
5. Centella asiatica improves memory and executive function in middle-aged rats by controlling oxidative stress and cholinergic transmission
6. Lead optimization based design, synthesis, and pharmacological evaluation of quinazoline derivatives as multi-targeting agents for Alzheimer's disease treatment
7. Design, synthesis, and biological evaluation of some 2-(3-oxo-5,6-diphenyl-1,2,4-triazin-2(3H)-yl)-N-phenylacetamide hybrids as MTDLs for Alzheimer's disease therapy
8. Suvorexant improves mitochondrial dynamics with the regulation of orexinergic and mTOR activation in rats exhibiting PTSD-like symptoms
9. Preparation, Characterization, in-vitro and in-vivo Pharmacokinetic Evaluation of Thermostable Dimethyl Fumarate Cocrystals
10. Development of multi-targetable chalcone derivatives bearing N-aryl piperazine moiety for the treatment of Alzheimer's disease
11. Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease
12. Indole-3-carbinol ameliorated the thioacetamide-induced hepatic encephalopathy in rats
13. Vasicinone, a pyrroloquinazoline alkaloid from Adhatoda vasica Nees enhances memory and cognition by inhibiting cholinesterases in Alzheimer's disease
14. Discovery of multi-target directed 3-OH pyrrolidine derivatives through a semisynthetic approach from alkaloid vasicine for the treatment of Alzheimer's disease
15. Identification of novel glucocerebrosidase chaperone for potential treatment of Parkinson's disease: An approach using in silico virtual screening, molecular docking and molecular dynamics, and in vitro studies
16. Effects of ELF-PEMF exposure on spontaneous alternation, anxiety, motor co-ordination and locomotor activity of adult wistar rats and viability of C6 (Glial) cells in culture
17. Standardization and validation of novel ex-vivo method for mitochondrial bioenergetics using mitochondrial modulators
18. Pharmacokinetic and Pharmacodynamic Properties of Indole-3-carbinol in Experimental Focal Ischemic Injury
19. Structure-Guided Design, Synthesis, and Biological Evaluation of Peripheral Anionic Site Selective and Brain Permeable Novel Oxadiazole-Piperazine Conjugates against Alzheimer’s Disease with Antioxidant Potential
20. In vivo toxicological evaluation of barium-doped bioactive glass in rats
21. An in vivo toxicity assessment of piezoelectric sodium potassium niobate [NaxK1-xNbO3 (x = 0.2–0.8)] nanoparticulates towards bone tissue engineering approach
22. Generation of wild-type rat Glucocerebrosidase homology modeling: Identification of putative interactions site and mechanism for chaperone using combined in-silico and in-vitro studies
23. Diindolylmethane ameliorates platelet aggregation and thrombosis: In silico, in vitro, and in vivo studies
24. Mitochondrial dysfunction in perinatal asphyxia: role in pathogenesis and potential therapeutic interventions
25. Dihydroquercetin ameliorates LPS-induced neuroinflammation and memory deficit
26. Oral Release Kinetics, Biodistribution, and Excretion of Dopants from Barium-Containing Bioactive Glass in Rats
27. Bioactive glass: A multifunctional delivery system
28. In-vitro analysis of bioactivity, hemolysis, and mechanical properties of Zn substituted Calcium Zirconium silicate (baghdadite)
29. Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer’s action: Design, synthesis, crystal structure and in-vitro biological evaluation
30. Synthesis and characterization of barium-doped bioactive glass with potential anti-inflammatory activity
31. Development and treatment of cognitive inflexibility in sub-chronic stress–re-stress (SRS) model of PTSD
32. Stem Cell-Based Therapy for Ischemic Stroke
33. Critical Role of Mitochondrial Autophagy in Cerebral Stroke
34. Impact of high-fat diet and exposure to constant light on reproductive competence of female ICR mice
35. Design and development of molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1,3,4-oxadiazoles as potential multifunctional agents to treat Alzheimer's disease
36. Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease
37. Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson’s disease
38. Neurochemical Evidence of Preclinical and Clinical Reports on Target-Based Therapy in Alcohol Used Disorder
39. Neuroprotective effect of chlorogenic acid in global cerebral ischemia-reperfusion rat model
40. Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease
41. Pharmacological application of barium containing bioactive glass in gastro-duodenal ulcers
42. A Comprehensive Review of Novel Pathophysiology, Approved and Non-approved Pharmacological Agents for PTSD Therapy
43. Chronic exposure to dim artificial light disrupts the daily rhythm in mitochondrial respiration in mouse suprachiasmatic nucleus
44. Development of Piperazinediones as dual inhibitor for treatment of Alzheimer's disease
45. Enhanced in vivo biocompatibility of magnesia-contained bioactive glasses
46. Preparation and in vitro investigation on bioactivity of magnesia-contained bioactive glasses
47. Dimethyl fumarate as a covalent inhibitor of Cathepsin C: a novel mechanism of action explored in in-vitro and in-vivo.
48. Rhodanine composite fluorescence probes to detect amyloid-beta aggregated species in Alzheimer's disease models
49. Development and Evaluation of Some Molecular Hybrids of N-(1-Benzylpiperidin-4-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio) as Multifunctional Agents to Combat Alzheimer’s Disease
50. 2,4 Dinitrophenol Attenuates Mitochondrial Dysfunction and Improves Neurobehavioral Outcomes Postanoxia in Neonatal Rats
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