Search

Your search keyword '"LePage C"' showing total 181 results
Start Over Author "LePage C" Search Limiters Peer Reviewed
181 results on '"LePage C"'

1. FOLFIRINOX as induction treatment in rectal cancer patients with synchronous metastases: Results of the FFCD 1102 phase II trial

Author

Dahan, L., Auby, D., Khemissa, F., Ghiringhelli, F., Nguyen, S., Bedjaoui, A., Terrebonne, E., Thaury, J., Baconnier, M., Bachet, J.B., Lucidarme, O., Levache, C.B., Barbier, E., Raoul, J.L., Lecomte, T., Desauw, C., Brocard, F., Pernot, S., Breysacher, G., Lagasse, J.P., Di Fiore, F., Etienne, P.L., Dupuis, O.J.M., Aleba, A., Lepage, C., and Taieb, J.

Published
2018
Full Text
View/download PDF

7. Poorly differentiated gastro-entero-pancreatic neuroendocrine carcinomas: Are they really heterogeneous? Insights from the FFCD-GTE national cohort

Author

Stephanie, Laetitia, Borbath, Ivan, Castex, Petorin, Caroline, Terrebonne, Eric, Bouhier-Leporrier, Karine, Suc, Etienne, Hautefeuille, Vincent, Bourgeois, Vincent, Cany, Laurent, Dewaele, François, Niccoli, Patricia, Seitz, Jean-François, Lecaille, Cédric, Rebischung, Christine, Rossi, Valérie, Baconnier, Mathieu, Dubreuil, Olivier, Ferec, Marc, Deplanque, Gael, Geslin, Guillaume, Wanicki Caron, Isabelle, Lavau Denes, Sandrine, Bedenne, Laurent, Ligeza, Catherine, Maringe, Eric, Ran-Royo, Anne-Laure, Guigay, Joel, Rougier, Philippe, Walter, T., Tougeron, D., Baudin, E., Le Malicot, K., Lecomte, T., Malka, D., Hentic, O., Manfredi, S., Bonnet, I., Guimbaud, R., Coriat, R., Lepère, C., Desauw, C., Thirot-Bidault, A., Dahan, L., Roquin, G., Aparicio, T., Legoux, J.-L., Lombard-Bohas, C., Scoazec, J.-Y., Lepage, C., and Cadiot, G.

Published
2017
Full Text
View/download PDF

9. Perioperative FOLFOX 4 Versus FOLFOX 4 Plus Cetuximab Versus Immediate Surgery for High-Risk Stage II and III Colon Cancers: A Phase II Multicenter Randomized Controlled Trial (PRODIGE 22)

Author

Karoui, M., Rullier, A., Piessen, G., Legoux, J. L., Barbier, E., De Chaisemartin, C., Lecaille, C., Bouche, O., Ammarguellat, H., Brunetti, F., Prudhomme, M., Regimbeau, J. M., Glehen, O., Lievre, A., Portier, G., Hartwig, J., Goujon, G., Romain, B., Lepage, C., and Taieb, J.

Published
2020
Full Text
View/download PDF

10. Annual cycle of Whitewinged Scoters (Melanitta fusca)in eastern North America: migratory phenology, population delineation, and connectivity

Author

McWilliams, S.R., Paton, P.W.C., Lepage, C., Gilliland, S.G., Savoy, L., Olsen, G.H., and Osenkowski, J.E.

Subjects
Ducks -- Research, Migratory birds -- Research, Breeding colonies -- Research, Animal wintering -- Research, Ornithological research, Zoology and wildlife conservation
Abstract

Understanding full annual cycle movements of long-distance migrants is essential for delineating populations, assessing connectivity, evaluating crossover effects between life stages, and informing management strategies for vulnerable or declining species. We used implanted satellite transmitters to track up to 2 years of annual cycle movements of 52 adult female Whitewinged Scoters (Melanitta fusca (Linnaeus, 1758)) captured in the eastern United States and Canada. We used these data to document annual cycle phenology; delineate migration routes; identify primary areas used during winter, stopover, breeding, and molt; and assess the strength of migratory connectivity and spatial population structure. Most Whitewinged Scoters wintered along the Atlantic coast from Nova Scotia to southern New England, with some on Lake Ontario. Whitewinged Scoters followed four migration routes to breeding areas from Quebec to the Northwest Territories. Principal postbreeding molting areas were in James Bay and the St. Lawrence River estuary. Migration phenology was synchronous regardless of winter or breeding origin. Cluster analyses delineated two primary breeding areas: one molting area and one wintering area. Whitewinged Scoters demonstrated overall weak to moderate connectivity among life stages, with molting to wintering connectivity the strongest. Thus, Whitewinged Scoters that winter in eastern North America appear to constitute a single continuous population.Key words: Whitewinged Scoter, Melanitta fusca, population delineation, migratory connectivity, annual cycle, satellite telemetry, phenology.La comprehension des deplacements sur un cycle annuel complet d'especes qui migrent sur de longues distances est fondamentale pour delimiter les populations, evaluer la connectivite et les effets de chevauchement de differentes etapes du cycle biologique et elaborer de strategies de gestion pour les especes vulnerables ou en declin. Nous avons utilise des emetteurs satellitaires implantes pour suivre le cycle de deplacement annuel pendant jusqu'a deux ans de 52 macreuses a ailes blanches (Melanitta fusca (Linnaeus, 1758)) femelles adultes capturees dans l'est des Etats-Unis et du Canada. Nous avons utilise ces donnees pour documenter la phenologie du cycle annuel, delimiter les routes de migration, cerner les principales aires d'hivernage, de sejour, de reproduction et de mue et evaluer la force de la connectivite migratoire et la structure spatiale de la population. La plupart des macreuses a ailes blanches hivernaient le long de la cote atlantique, de la Nouvelle-Ecosse au sud de la Nouvelle-Angleterre, certaines passant plutot l'hiver sur le lac Ontario. Les macreuses a ailes blanches suivaient quatre routes de migration vers des aires de reproduction allant du Quebec aux Territoires-du-Nord-Ouest. Les principales aires de mue apres la reproduction etaient dans la baie James et l'estuaire du fleuve Saint-Laurent. La phenologie de la migration etait synchrone, quelles que soient les aires d'hivernage ou de reproduction d'origine. Des analyses typologiques ont delimite deux principales aires de reproduction, une aire de mue et une aire d'hivernage. Les macreuses a ailes blanches presentaient globalement une connectivite faible a moderee entre les etapes du cycle biologique, la connectivite entre la mue et l'hivernage etant la plus forte. Ainsi, les macreuses a ailes blanches qui hivernent dans l'est de l'Amerique du Nord semblent constituer une seule population continue. [Traduit par la Redaction]Mots-cles : macreuse a ailes blanches, Melanitta fusca, delimitation des populations, connectivite migratoire, cycle annuel, telemetrie satellitaire, phenologie., IntroductionMonitoring movement patterns of long-distance migratory animals over space and time provides insights into key aspects of their ecology (Trierweiler et al. 2014; Hallworth et al. 2015; Stanley et al. [...]

Published
2018
Full Text
View/download PDF

12. The multidisciplinary management of gastro-oesophageal junction tumours: European Society of Digestive Oncology (ESDO): Expert discussion and report from the 16th ESMO World Congress on Gastrointestinal Cancer, Barcelona

Author

Van Laethem, J.-L., Carneiro, F., Ducreux, M., Messman, H., Lordick, F., Ilson, D.H., Allum, W.H., Haustermans, K., Lepage, C., Matysiak-Budnik, T., Cats, A., Schmiegel, W., Cervantes, A., Van Cutsem, E., Rougier, Ph., and Seufferlein, Th.

Published
2016
Full Text
View/download PDF

14. Randomized phase III trial in elderly patients comparing LV5FU2 with or without irinotecan for first-line treatment of metastatic colorectal cancer (FFCD 2001–02)

Author

Aparicio, T., Lavau-Denes, S., Phelip, J.M., Maillard, E., Jouve, J.L., Gargot, D., Gasmi, M., Locher, C., Adhoute, X., Michel, P., Khemissa, F., Lecomte, T., Provençal, J., Breysacher, G., Legoux, J.L., Lepère, C., Charneau, J., Cretin, J., Chone, L., Azzedine, A., Bouché, O., Sobhani, I., Bedenne, L., Mitry, E., Amoyal, P., Auby, D., Bachet, J.B., Baconnier, M., Benoit, R., Berthelet, O., Bidault, A., Bineau, C., Bordes, G., Bouarioua, N., Boucher, E., Boulat, O., Cleau, D., Couzigou, P., Cuillerier, E., Cumin, I., Denis, B., Di Fiore, F., Derias, V., Ezenfis, J., Faroux, R., Gagnaire, A., Gatineau-Sailliant, G., Garcia, B., Genet, D., Gueye, A., Hammel, P., Lagasse, J.P., Landi, B., Lepage, C., Lobry, C., Lombard-Bohas, C., Mabro, M., Mackiewicz, R., Martin, J., Moncoucy, X., Morvan, F., Mozer, M., Pauwels, M., Petit-Laurent, F., Pouderoux, P., Prost, P., Queuniet, A.M., Ramdani, M., Rebischung, C., Rougier, P., Schnee, M., Seitz, J.F., Stefani, L., Taïeb, J., Terrebonne, E., Texereau, P., Thaury, J., Tougeron, D., Weber, A., Ricard, F., Bonnetain, F., Masskouri, F., Choine, C., Guiliani, F., Le Pessec, G., Fattouh, H., Le Provost, N., Girault, C., and Schneider, M.

Published
2016
Full Text
View/download PDF

35. Incidence and management of malignant digestive endocrine tumours in a well defined French population

Author

Lepage, C., Bouvier, A.M., Phelip, J.M., Hatem, C., Vernet, C., and Faivre, J.

Subjects
Tumors -- Research -- Care and treatment, Digestive system diseases -- Care and treatment -- Research, Health, Care and treatment, Research, Health aspects
Abstract

Gut 2004;53:549-553. doi: 10.1136/gut.2003.026401 Background and aims: Little is known about the epidemiology of malignant digestive endocrine tumours. The aim of this study was to report on their incidence and [...]

Published
2004

45. Loss of SMARCB1 expression in colon carcinoma.

Author

Melloul, S., Mosnier, J.-F., Masliah-Planchon, J., Lepage, C., Le Malicot, K., Gornet, J.-M., Edeline, J., Dansette, D., Texereau, P., Delattre, O., Laurent Puig, P., Taieb, J., and Emile, J.-F.

Subjects
COLON (Anatomy), TUMOR suppressor genes, CARCINOMA
Abstract

SMARCB1 is a tumor suppressor gene, which is part of SWI/SNF complex involved in transcriptional regulation. Recently, loss of SMARCB1 expression has been reported in gastrointestinal carcinomas. Our purpose was to evaluate the incidence and prognostic value of SMARCB1 loss in colon carcinoma (CC). Patients with stage III CC (n = 1695), and a second cohort of 23 patients with poorly differentiated CC were analyzed. Immunohistochemistry for SMARCB1 was performed on tissue microarrays, and cases with loss of expression were controlled on whole sections. Loss of SMARCB1 was compared with the clinico-pathological and molecular characteristics, and the prognostic value was evaluated. Loss of SMARCB1 was identified in 12 of 1695 (0.7%) patients with stage III CC. Whole section controls showed a complete loss in only one of these cases, corresponding to a medullary carcinoma. SMARCB1 loss was not associated with histological grade, tumor size nor survival. In the cohort of poorly differentiated CC, we detected 2/23 (8.7%) cases with loss of SMARCB1; one was rhabdoid while the other had medullary and mucinous histology. These 2 cases were deficient for MisMatched Repair (dMMR) and mutated for BRAF. SMARCB1 loss is rare in stage III CC, but appears more frequent in poorly differentiated CC. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

46. Épidémiologie des tumeurs neuroendocrines intestinales.

Author

Lepage, C.

Subjects
*COLORECTAL cancer, *PROGNOSIS, *SMALL intestine, *DIAGNOSIS, *CARCINOID, *INSULINOMA
Abstract

Little is known about the epidemiology of digestive neuroendocrine tumours (NETs). NETs remain a rare cancer, representing 1% of all digestive cancers. In France, incidence rates are estimated to around 1.1/100,000 inhabitants in males and 0.9/100,000 in females. The incidence rates got increased over time, with probably more than 1,000 new cases per year in France. Because of their relatively good prognosis, NETs are the second more prevalent digestive cancer after colorectal cancer. Most digestive NETs are well-differentiated (WDNETs); poorly differentiated neuroendocrine carcinomas (PDNEC) account for less than 20% of the cases in most of the series. Among bowel-NETs, the most frequent anatomical localisations are colorectal and small bowel. Functional NETs are rare (<20%); most of them are carcinoids, insulinomas and gastrinomas. More than half NETs are metastatic at diagnosis, mainly in the liver. Tumour differentiation, histologic grade, anatomic site and stage are the main prognostic factors. WDNETs are slow-growing tumours (relative survival of 55% at 5 years), whereas PDNEC are highly aggressive (relative survival of 4.5% at 5 years). [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

48. Annual cycle of White-winged Scoters (Melanitta fusca) in eastern North America: migratory phenology, population delineation, and connectivity.

Author

Meattey, D.E., McWilliams, S.R., Paton, P.W.C., Lepage, C., Gilliland, S.G., Savoy, L., Olsen, G.H., and Osenkowski, J.E.

Subjects
WHITE-winged scoter, PHENOLOGY, CLUSTER analysis (Statistics)
Abstract

Copyright of Canadian Journal of Zoology is the property of Canadian Science Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results