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1. Comprehensive structural assignment of glycosaminoglycan oligo- and polysaccharides by protein nanopore

Author

Parisa Bayat, Charlotte Rambaud, Bernard Priem, Matthieu Bourderioux, Mélanie Bilong, Salomé Poyer, Manuela Pastoriza-Gallego, Abdelghani Oukhaled, Jérôme Mathé, and Régis Daniel

Subjects
Science
Abstract

Glycosaminoglycans (GAGs) are highly anionic functional polysaccharides with subtle structural variations that are very difficult to differentiate. Here the authors demonstrate proof-of-concept single-molecule detection by nanopore, taking a first step towards the ultimate goal of GAG sequencing.

Published
2022
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