Search

Your search keyword '"Minařík, J."' showing total 25 results
Start Over Author "Minařík, J." Search Limiters Peer Reviewed
25 results on '"Minařík, J."'

3. Mnohočetný myelom s primárním multifokálním extramedulárním postižením a raritní cytogenetickou změnou.

Author

Látal, V., Pika, T., Mlynárčiková, M., Balcárková, J., Hradil, D., Tichý, T., Buriánková, E., Minařík, J., and Papajík, T.

Abstract

Copyright of Transfusiology & Haematology Today / Transfuze a Hematologie Dnes is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

4. Hereditární hemoragická teleangiektazie (syndrom Rendu-Osler-Weber).

Author

Bradáčová, M., Faber, E., Minařík, J., Čtvrtlík, F., and Čecháková, E.

Abstract

Copyright of Transfusiology & Haematology Today / Transfuze a Hematologie Dnes is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023

5. Standardizace 18F-FDG PET/CT u pacientů s mnohočetným myelomem: Společné doporučení České myelomové skupiny a České společnosti nukleární medicíny.

Author

Havel, M., Jelínek, T., Pour, L., Štork, M., Minařík, J., Jungová, A., Špička, I., Pavlíček, P., Radocha, J., Maisnar, V., Wróbel, M., Sýkora, M., Ullrychová, J., Muroňová, L., Krčálová, E., Buriánková, E., Henzlová, L., Havlová, G., Zogala, D., and Hájek, R.

Abstract

Copyright of Nuclear Medicine / Nukleární Medicína is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023

6. Standardizace PET/CT u pacientů s mnohočetným myelomem – Společné doporučení České myelomové skupiny a České společnosti nukleární medicíny.

Author

Havel, M., Jelínek, T., Pour, L., Štork, M., Minařík, J., Jungová, A., Špička, I., Pavlíček, P., Radocha, J., Maisnar, V., Wróbel, M., Sýkora, M., Ullrychová, J., Muroňová, L., Krčálová, E., Buriánková, E., Henzlová, L., Havlová, G., Zogala, D., and Hájek, Hm R.

Abstract

Copyright of Transfusiology & Haematology Today / Transfuze a Hematologie Dnes is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023

8. Assessment of Heavy/ Light Chain Pairs of Immunoglobulin (Hevylite™ assay) – Benefit for Stratification of Multiple Myeloma?

Author

J. Bačovský, T. Pika, J Zapletalová, Ščudla, Lochaman P, and Minařík J

Subjects
Immunoglobulin A, medicine.medical_specialty, Creatinine, biology, Chemistry, Beta-2 microglobulin, medicine.disease, Isotype, Gastroenterology, Immunoglobulin G, chemistry.chemical_compound, Oncology, Internal medicine, Immunology, biology.protein, medicine, Immunoglobulin heavy chain, Antibody, Multiple myeloma
Abstract

BACKGROUND The aim of the study was the comparison of two novel stratification models in multiple myeloma (MM), ie. according to Avet- Loiseau (A L) and according to Ludwig (L), based on the HLC r index (ratio of serum levels of involved- HLC/ uninvolved HLC, ie. HLC κ/ HLC λ assessed using ie. nephelometric/turbidimetric technique using specific polyclonal antibodies on a Binding Site SPA(PLUS)) technique) and β(2) microglobulin (β(2) M) with selected prognostic factors (PF) of MM and staging systems according to Durie- Salmon (D S) and International Staging System (ISS). PATIENTS AND METHODS In a cohort of 132 patients (94 with IgG and 38 with IgA type of MM) at the time of dia-gnosis, we assessed HLC r, select-ed PF and D S, ISS, A L and L stratification systems. RESULTS Unlike in IgA isotype, in IgG isotype we found a significant relationship of HLC r to stratification according to D S and ISS with the difference between A and B substages according to D S (p = 0.049) and between ISS stages 1 vs. 3 (p = 0.001). In the IgG group, there was highly significant relationship of the depth of Hb and albumin decrease and β(2) M increase to the results of stratification according to ISS, A L and L model (p < 0.0001), increase of LDH in the ISS system and A L, and creatinine according to ISS and L but not the relationship of the stages according to any of the stratification systems to the values of FLC r (ratio of serum free light chains κ/ λ of immunoglobulin), thrombocytes and Ca. In the IgA type, there was a significant relationship of the depth of the decrease of Hb, thrombocytes, albumin and increase of β(2) M to the results of stratification according to ISS, A L and L and increase of creatinine in the case of ISS, but not of the values of FLC r, Ca and LDH in the case of any of the stratification systems. The degree of correlation of selected PF, especially of Hb, albumin and β(2) M, event. of thrombocytes, LDH and creatinine to the stages according to ISS and to stage 1-3 according to A L and L model was in IgG vs IgA isotype significantly different (p < 0.0001- 0.030). Staging system according to ISS had proportional distribution of stages 1- 3, whereas in the A L model prevailed in IgA and IgG isotype risk category 2, ie. intermediate-risk (47.3 and 44.7%) and in the L model prevailed risk category 3, ie. high-risk (41.5 and 52.6%) with low count of category 1, ie. low- risk category (23.4 and 10.5%). McNemar- Bowker test of symmetry showed in both types of MM the highest concordance between the stratification according to D S and L in category 3, ie. high-risk (31.9 vs. 28.9%) with overall accord only in 53.2 and 42.1% and with significant shift in the case of IgG isotype only (p = 0.036). In IgG and IgA isotype there was an overall concordance in the distribution of categories 1- 3 according to ISS vs. A L (62.4 and 63.2%) but with significant shift of the stratification (p = 0.002 and 0.028). In the case of IgG and IgA isotype there was a close relationship between the models A L and L (64.5 and 81.6%) with significant stratification shift (p < 0.0001 and 0.030). CONCLUSION The new stratification models for MM according to A L and L are easily practically applicable, with close relationship to principal PF but they need separate assessment of IgG and IgA isotypes of MM. The choice of optimal model for routine practice needs a validation study aimed at progression free survival and overall survival.

Published
2015
Full Text
View/download PDF

9. SMĚS A DOTAZY

Author

Minařík, J. V. Stan, Šolta, A., Rais, K. V., and Šebestová-Ledecká, Anna

Published
1901

11. Depression and Alcohol Use Disorders.

Author

BROKLOVÁ, L., SŤASTNÁ, L., and MINAŘÍK, J.

Subjects
ALCOHOL drinking, ADDICTIONS, PSYCHOTHERAPY
Abstract

Copyright of Addictology / Adiktologie is the property of Sdruzeni SCAN as a publisher of journal Adiktologie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2017

13. Analýza parametrů signálních drah myelomové kostní nemoci u mnohočetného myelomu.

Author

Krhovská, P., Heřmanová, Z., Petrová, P., Zapletalová, J., Pika, T., Bačovský, J., Ščudla, V., and Minařík, J.

Abstract

Copyright of Klinická Biochemie a Metabolismus is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2016

14. Vztah hladin molekul BAFF a APRIL k vybraným ukazatelům mnohočetného myelomu.

Author

Pika, T., Heřmanová, Z., Lochman, P., Minařík, J., Krhovská, P., Zapletalová, J., and Ščudla, V.

Abstract

Copyright of Klinická Biochemie a Metabolismus is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2016

17. Výzkum efektivity preventivních intervencí všeobecné školské prevence v České republice a na Slovensku.

Author

GABRHELÍK, R., OROSOVÁ, O., MIOVSKÝ, M., VOŇKOVÁ, H., BERINŠTEROVÁ, M., and MINAŘÍK, J.

Abstract

Copyright of Addictology / Adiktologie is the property of Sdruzeni SCAN as a publisher of journal Adiktologie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2014

18. Delece TP53 u nemocných s mnohočetným myelomem a monoklonální gamapatií nejistého významu -- molekulárně cytogenetická analýza souboru 84 nemocných.

Author

Mičková, P., Balcárková, J., Pika, T., Ščudla, V., Bačovský, J., Minařík, J., Nevimová, K., and Jarošová, M.

Abstract

Copyright of Transfusiology & Haematology Today / Transfuze a Hematologie Dnes is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2014

20. Význam stanovení sérových hladin volných lehkých řetĕzců imunoglobulinu u AL amyloidózy.

Author

Pika, T., Lochman, P., Minařík, J., Bačovský, J., and Ščudla, V.

Subjects
IMMUNOGLOBULINS, AMYLOIDOSIS, MONOCLONAL gammopathies, MONOCLONAL antibodies, PROTEIN analysis, BLOOD serum analysis
Abstract

Copyright of Transfusiology & Haematology Today / Transfuze a Hematologie Dnes is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2013

22. Kolapsový stav u 18leté dívky -- kazuistika.

Author

Minařík, J., Skácelová, M., Horák, P., Smržová, A., Faltýnek, L., and Ščudla, V.

Subjects
*MACROCYTIC anemia, *ANEMIA diagnosis, *DIFFERENTIAL diagnosis, *CELIAC disease, DIAGNOSIS of digestive system diseases
Abstract

The aim of this paper is to report a less frequent cause of collapse associated with minimal clinical symptoms in an 18-year old female. Laboratory examinations revealed severe macrocytic anaemia (Hb 35 g/l, MCV 114 fl) with mild alteration of biochemical parameters. The differential diagnosis focused on a possible malabsorption syndrome, which was finally confirmed in the form of celiac disease. Dietary measures as well as substitution therapy lead to rapid normalization of laboratory parameters and an improvement in the patient's clinical condition. The aim of our paper is to draw attention to less frequent manifestations of celiac disease and to possible pitfalls of routine differential diagnosis of anaemia. [ABSTRACT FROM AUTHOR]

Published
2012

24. Náhlá progrese mnohočetného myelomu charakterizovaná parciálním „light-chain escape" fenoménem a sekundární translokací t(8;14).

Author

Pika, T., Balcárková, J., Lochman, P., Minařík, J., Jarošová, M., Raida, L., Bačovský, J., and Ščudla, V.

Subjects
MULTIPLE myeloma, DRUG therapy, STEM cells, PATIENTS, KARYOTYPES
Abstract

Copyright of Transfusiology & Haematology Today / Transfuze a Hematologie Dnes is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2011

25. TEMPORARY REMOVAL: PO-48: Coagulopathy in multiple myeloma.

Author

Chasakova, K., Slavík, L., Starostka, D., Úlehlová, J., Papajík, T., and Minařík, J.

Subjects
*MULTIPLE myeloma, *BLOOD coagulation disorders
Abstract

The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results