Search

Your search keyword '"Mohammad Hasan Moradinejad"' showing total 2 results
Start Over Author "Mohammad Hasan Moradinejad" Search Limiters Peer Reviewed
2 results on '"Mohammad Hasan Moradinejad"'

1. Prevalence of IgA Deficiency in Children with Juvenile Rheumatoid Arthritis

Author

Mohammad Hasan Moradinejad, Ali Hoseinpoor Rafati, Maryam Ardalan, Mahnaz Rabiei, Maryam Farghadan, Mohammad Taghi Haghi Ashtiani, Zahra Pourpak, and Mostafa Moin

Subjects
IgA Deficiency, Juvenile Rheumatoid Arthritis, Medicine
Abstract

The purpose of this study was to investigate any association between IgA deficiency (IgAD) and juvenile rheumatoid arthritis (JRA) among Iranian children. This case-control study was carried out on 83 children who were diagnosed as JRA according to American College of Rheumatology (ACR) criteria; Patients were admitted at the rheumatology clinic of Children's Medical Center, (Tehran). Serum immunoglobulins concentrations were determined by nephelometry method. Control group was 112 healthy children who were matched for age and gender. Informed consent obtained from all parents. Selective IgA deficiency (sIgAD) was found only in a boy (1.2%) among JRA children; however, partial IgA deficiency was found in 6(7.1%) of patients with JRA and in 12(10.7%) of control subjects, this difference was not statistically significant (p=0.46). Immunoglobulins levels in patients with JRA (IgM: 126.7±57.2, IgG: 1182.3±351 and IgA:169.3±98) were significantly higher than their controls (IgM: 104±52, IgG:802±220 and IgA: 94.6±47) (pPatients with growth failure had higher IgM, IgG and IgA levels in comparison with patients without growth failure; however, this difference was significant about IgM and IgG levels (p

Published
2011

2. Outcome of lupus nephritis in Iranian children: prognostic significance of certain features

Author

Neamatollah Ataei, Manijeh Haydarpour, Abbas Madani, Niloufar Hajizadeh, Taghi Gholmohammadi, Seyed Taher Esfahani, Mohammad Hasan Moradinejad, Shahriar Arbabi, and Marzieh Haddadi

Subjects
Male, Nephrology, medicine.medical_specialty, Time Factors, Multivariate analysis, Adolescent, Biopsy, Lupus nephritis, Iran, Kidney, Independent predictor, Gastroenterology, Risk Factors, Internal medicine, medicine, Humans, In patient, Child, Glucocorticoids, Retrospective Studies, business.industry, Mean age, Prognosis, medicine.disease, Lupus Nephritis, Renal histology, Surgery, Survival Rate, Child, Preschool, Pediatrics, Perinatology and Child Health, Female, business, Renal survival, Immunosuppressive Agents, Follow-Up Studies
Abstract

The objective of this study was to determine the clinical and histopathological features and outcome of children with lupus nephritis (LN). Of 84 children with systemic lupus erythematosus (SLE), we retrospectively studied 58 children (69%) under 15 years of age with biopsy-proven LN who had been followed between October 1989 and January 2005. The mean age at diagnosis or initial referral was 10.6 +/- 2.25 years, and the mean follow-up was 5.3 +/- 4.1 years. Class IV LN was observed in 34 (58.6%) patients. The 5-year patient and renal survival rates were 82.5 and 78.5%, respectively, in the total group, and 75 and 85.8%, respectively, in patients with Class IV LN. No independent predictor of unfavorable outcome, including renal histology, was detected by multivariate analysis. The mid-term patient and the renal survival rates of Iranian children with biopsy-proven LN are high. Within 5 years of follow-up, renal histology was not a predictor for survival.

Published
2008
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results