30 results on '"Nair, Sajiv K."'
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2. Construction of Isoquinolone Scaffolds on DNA via Rhodium(III)-Catalyzed C–H Activation.
3. Recent progress on third generation covalent EGFR inhibitors
4. Preparation and physicochemical characterization of a novel water-soluble prodrug of carbamazepine
5. Rhodium(III)-Catalyzed C–H Activation: Annulation of Petrochemical Feedstocks for the Construction of Isoquinolone Scaffolds.
6. Multifaceted Substrate–Ligand Interactions Promote the Copper-Catalyzed Hydroboration of Benzylidenecyclobutanes and Related Compounds.
7. Total synthesis and evaluation of C26-hydroxyepothilone D derivatives for photoaffinity labeling of [beta]-tubulin
8. Synthesis of cryptophycins via an N-acly-beta-lactam macrolactonization
9. Total synthesis of cryptophycin-24 (Arenastatin A) amenable to structural modifications in the C16 side chain
10. Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR...
11. Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
12. Synthesis of Small 3-Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry.
13. N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: Strategies to eliminate reactive metabolites
14. Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility
15. Novel synthesis of CP-734432, an EP4 agonist, using Sharpless asymmetric dihydroxylation
16. Total Synthesis and Evaluation of C26-Hydroxyepothilone D Derivatives for Photoaffinity Labeling of β-Tubulin.
17. Synthesis of Cryptophycins via an N-Acyl-β-lactam Macrolactonization.
18. An efficient synthesis of α-(trimethylsilyl)allenyl ketones.
19. Practical syntheses of the C12–C21 epothilone subunit via catalytic asymmetric reductions: Itsuno–Corey oxazaborolidine reduction and asymmetric Noyori hydrogenation
20. ChemInform Abstract: Recent Progress on Third Generation Covalent EGFR Inhibitors.
21. Diastereoselective access to substituted 4-aminopiperidines via a pyridine reduction approach.
22. ChemInform Abstract: Rapid Entry into the Cryptophycin Core via an Acyl-β-lactam Macrolactonization: Total Synthesis of Cryptophycin-24.
23. ChemInform Abstract: Total Synthesis of Cryptophycin-24 (Arenastatin A) (III) Amenable to Structural Modifications in the C16 Side Chain.
24. ChemInform Abstract: An Efficient Gram-Scale Synthesis of (+)-Discodermolide.
25. Cycloaromatization of a solvolytically generated ene-yne-allene
26. Total synthesis and evaluation of C25-benzyloxyepothilone C for tubulin assembly and cytotoxicity against MCF-7 breast cancer cells
27. The development and SAR of pyrrolidine carboxamide 11β-HSD1 inhibitors
28. N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275
29. Total synthesis and evaluation of 22-(3-azidobenzoyloxy)methyl epothilone C for photoaffinity labeling of β-tubulin
30. 2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases
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