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386 results on '"Pambuccian, Stefan"'

2. Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients

Author

Adamson, Kathi, Albain, Kathy S., Asare, Adam L., Asare, Smita M., Balassanian, Ron, Beckwith, Heather, Berry, Scott M., Berry, Donald A., Boughey, Judy C., Buxton, Meredith B., Chen, Yunn-Yi, Chen, Beiyun, Chien, A. Jo, Chui, Stephen Y., Clark, Amy S., Clennell, Julia L., Datnow, Brian, DeMichele, Angela M., Duan, Xiuzhen, Edmiston, Kirsten K., Elias, Anthony D., Ellis, Erin D., Esserman, Laura L., Euhus, David M., Fadare, Oluwole, Fan, Fang, Feldman, Michael D, Forero-Torres, Andres, Haley, Barbara B., Han, Hyo S., Harada, Shuko, Haugen, Patricia, Helsten, Teresa, Hirst, Gillian L., Hylton, Nola M., Isaacs, Claudine, Kemmer, Kathleen, Khan, Qamar J., Khazai, Laila, Klein, Molly E., Krings, Gregor, Lang, Julie E., LeBeau, Lauren G., Leyland-Jones, Brian, Liu, Minetta C., Lo, Shelly, Lu, Janice, Magliocco, Anthony, Matthews, Jeffrey B., Melisko, Michelle E., Mhawech-Fauceglia, Paulette, Moulder, Stacy L., Murthy, Rashmi K., Nanda, Rita, Northfelt, Donald W., Ocal, Idris T., Olopade, Olufunmilayo, Pambuccian, Stefan, Paoloni, Melissa, Park, John W., Parker, Barbara A., Perlmutter, Jane, Peterson, Garry, Pusztai, Lajos, Rendi, Mara, Rugo, Hope S., Sahoo, Sunati, Sams, Sharon, Sanil, Ashish, Sattar, Husain, Schwab, Richard B., Singhrao, Ruby, Steeg, Katherine, Stringer-Reasor, Erica, Symmans, W. Fraser, Tawfik, Ossama, Tripathy, Debasish, Troxell, Megan L., van't Veer, Laura J., Venters, Sara J., Vinh, Tuyethoa, Viscusi, Rebecca K., Wallace, Anne M., Wei, Shi, Wilson, Amy, Yau, Christina, Yee, Douglas, Zeck, Jay C., Osdoit, Marie, van der Noordaa, Marieke, Shad, Sonal, Wei, Jane, de Croze, Diane, Hamy, Anne-Sophie, Laé, Marick, Reyal, Fabien, Sonke, Gabe S, Steenbruggen, Tessa G, van Seijen, Maartje, Wesseling, Jelle, Martín, Miguel, del Monte-Millán, Maria, López-Tarruella, Sara, Boughey, Judy C, Goetz, Matthew P, Hoskin, Tanya, Gould, Rebekah, Valero, Vicente, Edge, Stephen B, Abraham, Jean E, Bartlett, John M S, Caldas, Carlos, Dunn, Janet, Earl, Helena, Hayward, Larry, Hiller, Louise, Provenzano, Elena, Sammut, Stephen-John, Thomas, Jeremy S, Cameron, David, Graham, Ashley, Hall, Peter, Mackintosh, Lorna, Godwin, Andrew K, Schwensen, Kelsey, Sharma, Priyanka, DeMichele, Angela M, Cole, Kimberly, Kim, Mi-Ok, van 't Veer, Laura J, Esserman, Laura J, and Symmans, W Fraser

Published
2022
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11. E-Cigarette or Vaping Product Use-Associated Lung Injury: A Review for Pathologists

Author

Cecchini, Matthew J., Mukhopadhyay, Sanjay, Arrossi, Andrea V., Beasley, Mary B., Butt, Yasmeen M., Jones, Kirk D., Pambuccian, Stefan, Mehrad, Mitra, Monaco, Sara E., Saqi, Anjali, Smith, Maxwell L., Tazelaar, Henry D., and Larsen, Brandon T.

Subjects
Clinical pathology, Electronic cigarettes -- Usage -- Health aspects, Health
Abstract

* Context.--Vaping is the inhalation of heated aerosol from a small battery-powered device as a method to deliver nicotine or other substances. A recent outbreak of severe respiratory illness primarily in the United States has put a spotlight on vaping and its potential risks. Objective.--To familiarize pathologists with vaping, the cytologic and histopathologic features of vaping-associated acute lung injury, and the role of pathology in this diagnosis. Data Sources.--A targeted literature review was performed. Conclusions.--Most cases of vaping-associated lung injury have been linked to vaping products containing tetrahydrocannabinol or other cannabinoids. Lung biopsies show a spectrum of nonspecific acute lung injury patterns (organizing pneumonia, diffuse alveolar damage, acute fibrinous, and organizing pneumonia, or combinations of the above), accompanied by prominent, foamy macrophage accumulation. Injury is usually accentuated around small airways. Lipid-laden macrophages can be identified in bronchioloalveolar lavage fluid in most patients and these can be highlighted using lipid stains, such as oil red O, but the clinical utility of this finding remains unclear, as lipid-laden macrophages can be seen in a wide variety of processes and should not be relied upon to make the diagnosis. Classic histologic features of exogenous lipoid pneumonia have not been identified in tissue samples. Lightly pigmented macrophages, similar to those seen with traditional cigarette smoking, are present in some cases but are usually a minor feature. To date, no specific pathologic features for vaping-related injury have been identified, and it remains a diagnosis of exclusion that requires clinic-pathologic correlation. doi: 10.5858/arpa.2020-0024-RA, WHAT IS VAPING? A PRIMER ON DEVICES, CONTENTS, AND TERMINOLOGY 'Vaping' is the inhalation of an aerosol (vapor) generated by heating a liquid in a small batterypowered device. (1-3) This [...]

Published
2020
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27. HPV-related Multiphenotypic Sinonasal Carcinoma: An Expanded Series of 49 Cases of the Tumor Formerly Known as HPV-related Carcinoma With Adenoid Cystic Carcinoma-like Features

Author

Bishop, Justin A., Andreasen, Simon, Hang, Jen-Fan, Bullock, Martin J., Chen, Tiffany Y., Franchi, Alessandro, Garcia, Joaquin J., Gnepp, Douglas R., Gomez-Fernandez, Carmen R., Ihrler, Stephan, Kuo, Ying-Ju, Lewis, James S., Jr, Magliocca, Kelly R., Pambuccian, Stefan, Sandison, Ann, Uro-Coste, Emmanuelle, Stelow, Edward, Kiss, Katalin, and Westra, William H.

Published
2017
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47. Glycerol monolaurate prevents mucosal SIV transmission

Author

Li, Qingsheng, Estes, Jacob D., Schlievert, Patrick M., Duan, Lijie, Brosnahan, Amanda J., Southern, Peter J., Reilly, Cavan S., Peterson, Marnie L., Schultz-Darken, Nancy, Brunner, Kevin G., Nephew, Karla R., Pambuccian, Stefan, Lifson, Jeffrey D., Carlis, John V., and Haase, Ashley T.

Subjects
Glycerin -- Health aspects -- Research, Glycerol -- Health aspects -- Research, Simian immunodeficiency virus -- Health aspects -- Diagnosis -- Prevention -- Research -- Genetic aspects, Virus diseases -- Causes of -- Prevention -- Diagnosis -- Genetic aspects -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation, Diagnosis, Prevention, Genetic aspects, Research, Causes of, Health aspects
Abstract

Although there has been great progress in treating human immunodeficienry virns 1 (HIV-1) infection (1), preventing transmission has thus far proven an elusive goal. Indeed, recent trials of a candidate vaccine and microbicide have been disappointing, both for want of efficacy and concerns about increased rates of transmission (2-4). Nonetheless, studies of vaginal transmission in the simian immunodeficienry virus (SIV)-rhesus macaque (Macacca mulatta) model point to opportunities at the earliest stages of infection in which a vaccine or microbicide might be protective, by limiting the expansion of infected founder populations at the portal of entrys (5-6). Here we show in this SIV-macaque model, that an outside-in endocervical mucosal signalling system, involving MIP-3 α (also known as CCL20), plasmarytoid dendritic cells and [CCR5.sup.+] cell-attracting chemokines produced by these cells, in combination with the innate immune and inflammatory responses to infection in both cervix and vagina, recrnits [CD4.sup.+] T cells to fuel this obligate expansion. We then show that glycerol monolaurate--a widely used antimicrobial compound (7) with inhibitory activity against the production of MIP-3α and other proinflammatory cytokines (8)--can inhibit mucosal signalling and the innate and inflammatory response to HIV-1 and SIV in vitro, and in vivo it can protect rhesus macaques from acute infection despite repeated intra-vaginal exposure to high doses of SIV. This new approach, plausibly linked to interfering with innate host responses that recruit the target cells necessary to establish systemic infection, opens a promising new avenue for the development of effective interventions to block HIV-1 mucosal transmission., To understand how SIV infection in a small founder population of cells at the portal of entry transitions in less than two weeks to systemic infection, with massive levels of [...]

Published
2009

48. Unsatisfactory SurePath liquid-based Papanicolaou tests: causes and Significance

Author

Alsharif, Mariam, McKeon, Dan M., Gulbahce, H. Evin, Savik, Kay, and Pambuccian, Stefan E.

Subjects
Pap test -- Usage, Pap test -- Quality management, Pap test -- Research, Cervical cancer -- Diagnosis, Cervical cancer -- Research, Cancer -- Diagnosis, Cancer -- Quality management, Cancer -- Research, Health
Published
2009

50. Impact of the more restrictive definition of atypical squamous cells introduced by the 2001 Bethesda system on the sensitivity and specificity of the papanicolaou test: a 5-year follow-up study of papanicolaou tests originally interpreted as ASCUS, reclassified according to Bethesda 2001 criteria

Author

Thrall, Michael J., Pambuccian, Stefan E., Stelow, Edward B., McKeon, Dan W., Miller, Lizette, Savik, Kay, and Gulbahce, H. Evin

Subjects
Squamous cell carcinoma -- Diagnosis, Pap test -- Usage, Pap test -- Standards, Pap test -- Quality management, Cancer -- Diagnosis, Cancer -- Quality management, Cancer -- Standards, Cancer -- Research, Health
Published
2008

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