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Your search keyword '"Paul Mereuta"' showing total 4 results
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4 results on '"Paul Mereuta"'

1. Nanocellulose-enriched hydrocolloid-based hydrogels designed using a Ca2+ free strategy based on citric acid

Author

Adriana Lungu, Alexandra I. Cernencu, Sorina Dinescu, Roxana Balahura, Paul Mereuta, Marieta Costache, Kristin Syverud, Izabela C. Stancu, and Horia Iovu

Subjects
Hydrocolloids, Wood-derived nanocellulose, Cellulose nanofibrils, Polysaccharide-based hydrogels, Ca2+ free hydrogels, Citric acid-crosslinked hydrogels, Materials of engineering and construction. Mechanics of materials, TA401-492
Abstract

In this work fully biomass-based hydrogels were developed using a naturally occurring vegetable hydrocolloid co-mingled with wood-derived nanocellulose fibrils. Two distinct types of hydrocolloids have been considered: a seaweed-derived biopolymer (alginate) and a plant-derived biopolymer (pectin). To attain nano-structured binary hydrogels, surface-functionalized cellulose nanofibrils (CNFs) bearing carboxyl groups were employed. This study addresses a non-conventional approach of physical gelation that takes place in acidic conditions (pH

Published
2021
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3. 3D Bioprinting of Biosynthetic Nanocellulose-Filled GelMA Inks Highly Reliable for Soft Tissue-Oriented Constructs

Author

Diana Dragusin, Izabela C. Stancu, Sorina Dinescu, Horia Iovu, Paul Mereuta, Marieta Costache, Adriana Lungu, Alexandra I. Cernencu, and Liliana R Balahura

Subjects
Technology, food.ingredient, Materials science, Biocompatibility, Oxidized cellulose, Gelatin, Article, 3D bioprinting, methacrylamide-modified gelatin, cellulose nanofibrils, biomaterial inks, 3D nanocomposite scaffolds, Nanocellulose, law.invention, chemistry.chemical_compound, food, law, General Materials Science, Microscopy, QC120-168.85, QH201-278.5, Biomaterial, Engineering (General). Civil engineering (General), TK1-9971, Descriptive and experimental mechanics, chemistry, Self-healing hydrogels, Electrical engineering. Electronics. Nuclear engineering, TA1-2040, Biofabrication, Biomedical engineering
Abstract

Bioink-formulations based on gelatin methacrylate combined with oxidized cellulose nanofibrils are employed in the present study. The parallel investigation of the printing performance, morphological, swelling, and biological properties of the newly developed hydrogels was performed, with inks prepared using methacrylamide-modified gelatins of fish or bovine origin. Scaffolds with versatile and well-defined internal structure and high shape fidelity were successfully printed due to the high viscosity and shear-thinning behavior of formulated inks and then photo-crosslinked. The biocompatibility of 3D-scaffolds was surveyed using human adipose stem cells (hASCs) and high viability and proliferation rates were obtained when in contact with the biomaterial. Furthermore, bioprinting tests were performed with hASCs embedded in the developed formulations. The results demonstrated that the designed inks are a versatile toolkit for 3D bioprinting and further show the benefits of using fish-derived gelatin for biofabrication.

Published
2021
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