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Inpatient rehabilitation application to this patient population is novel, as their potential for meeting developmental milestones has improved with the advent of disease-modifying treatments. Novel treatments have dramatically improved the medical and functional prognosis for patients with SMA. It is also not known how rehabilitation therapy frequency and intensity may influence outcomes, as therapy regimens for the 15 patients were not reported.[4] We present a case of a patient with SMA treated with onasemnogene abeparvovec-xioi who was admitted to inpatient rehabilitation. [Extracted from the article]

Using vignettes of real cases and the SimulConsult diagnostic decision support software, neurologists listed a differential diagnosis and workup before and after using the decision support. Using the software, there was a significant reduction in error, up to 75% for diagnosis and 56% for workup. This error reduction occurred despite the baseline being one in which testers were allowed to use narrative resources and Web searching. A key factor that improved performance was taking enough time (>2 minutes) to enter clinical findings into the software accurately. Under these conditions and for instances in which the diagnoses changed based on using the software, diagnostic accuracy improved in 96% of instances. There was a 6% decrease in the number of workup items accompanied by a 34% increase in relevance. The authors conclude that decision support for a neurological diagnosis can reduce errors and save on unnecessary testing. [ABSTRACT FROM PUBLISHER]

We report a child presenting with intermittent ophthalmoplegia and fluctuating ptosis and facial weakness whose evaluation revealed no evidence of myasthenia gravis but did reveal hyperthyroidism secondary to Graves disease. Successful treatment of the child’s endocrinopathy resulted in complete resolution of his presenting symptoms. Children presenting with ophthalmoplegia and ptosis without proptosis should be evaluated for hyperthyroidism if no evidence of a myopathy or disorder of neuromuscular junction transmission is found. [ABSTRACT FROM PUBLISHER]