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14 results on '"Röh, Astrid"'

3. The impact of a digital guideline version on schizophrenia guideline knowledge: results from a multicenter cluster-randomized controlled trial

Author

Halms, Theresa, Gaigl, Gabriele, Lorenz, Carolin, Güler, Duygu, Khorikian-Ghazari, Naiiri, Röh, Astrid, Burschinski, Angelika, Gaebel, Wolfgang, Flick, Marisa, Pielenz, Charline, Salveridou-Hof, Eva, Schneider-Axmann, Thomas, Schneider, Marco, Wagner, Elias, Falkai, Peter, Lucae, Susanne, Rentrop, Michael, Zwanzger, Peter, Seemüller, Florian, Landgrebe, Michael, Ortner, Marion, Schneeweiß, Bertram, Brieger, Peter, Ajayi, Klemens, Schwarz, Michael, Heres, Stephan, Marstrander, Nicolay, Becker, Thomas, Jäger, Markus, Putzhammer, Albert, Frasch, Karel, Steber, Raimund, Leucht, Stefan, and Hasan, Alkomiet

Published
2024
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4. Step away from depression—results from a multicenter randomized clinical trial with a pedometer intervention during and after inpatient treatment of depression

Author

Große, Julia, Huppertz, Charlotte, Röh, Astrid, Oertel, Viola, Andresen, Sara, Schade, Niklas, Goerke-Arndt, Franziska, Kastinger, Anna, Schoofs, Nikola, Thomann, Philipp Arthur, Henkel, Karsten, Malchow, Berend, Plag, Jens, Terziska, Aleksandra, Brand, Ralf, Helmig, Frank, Schorb, Alexander, Wedekind, Dirk, Jockers-Scherübl, Maria, Schneider, Frank, Petzold, Moritz Bruno, and Ströhle, Andreas

Published
2024
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6. Exercise as an add-on treatment in individuals with schizophrenia: Results from a large multicenter randomized controlled trial

Author

Maurus, Isabel, Roell, Lukas, Lembeck, Moritz, Papazova, Irina, Greska, David, Muenz, Susanne, Wagner, Elias, Campana, Mattia, Schwaiger, Rebecca, Schneider-Axmann, Thomas, Rosenberger, Kerstin, Hellmich, Martin, Sykorova, Eliska, Thieme, Cristina E., Vogel, Bob O., Harder, Carolin, Mohnke, Sebastian, Huppertz, Charlotte, Roeh, Astrid, Keller-Varady, Katriona, Malchow, Berend, Walter, Henrik, Wolfarth, Bernd, Wölwer, Wolfgang, Henkel, Karsten, Hirjak, Dusan, Schmitt, Andrea, Hasan, Alkomiet, Meyer-Lindenberg, Andreas, and Falkai, Peter

Published
2023
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8. Structured implementation of digital, systematically updated guideline recommendations for enhanced adherence in schizophrenia (SISYPHOS)—protocol of a cluster-randomized trial

Author

Lorenz, Carolin, Gaigl, Gabriele, Güler, Duygu, Halms, Theresa, Khorikian-Ghazari, Naiiri, Röh, Astrid, Schneider, Marco, Wagner, Elias, Schneider-Axmann, Thomas, Kapfhammer, Angelika, Flick, Marisa, Pielenz, Charline, Salveridou-Hof, Eva, Falkai, Peter, Gaebel, Wolfgang, Hasan, Alkomiet, and Leucht, Stefan

Published
2022
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10. Add-on spironolactone as antagonist of the NRG1-ERBB4 signaling pathway for the treatment of schizophrenia: Study design and methodology of a multicenter randomized, placebo-controlled trial

Author

Hasan, Alkomiet, Roeh, Astrid, Leucht, Stefan, Langguth, Berthold, Hansbauer, Maximilian, Oviedo-Salcedo, Tatiana, Kirchner, Sophie K., Papazova, Irina, Löhrs, Lisa, Wagner, Elias, Maurus, Isabel, Strube, Wolfgang, Rossner, Moritz J., Wehr, Michael C., Bauer, Ingrid, Heres, Stephan, Leucht, Claudia, Kreuzer, Peter M., Zimmermann, Stephanie, Schneider-Axmann, Thomas, Görlitz, Thomas, Karch, Susanne, Egert-Schwender, Silvia, Schossow, Beate, Rothe, Philipp, and Falkai, Peter

Published
2020
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13. Neurobiological effects of aerobic exercise, with a focus on patients with schizophrenia.

Author

Maurus, Isabel, Hasan, Alkomiet, Röh, Astrid, Takahashi, Shun, Rauchmann, Boris, Keeser, Daniel, Malchow, Berend, Schmitt, Andrea, and Falkai, Peter

Subjects
AEROBIC exercises, PEOPLE with schizophrenia, NEUROBIOLOGY, BRAIN physiology, SCHIZOPHRENIA treatment
Abstract

Schizophrenia is a severe neuropsychiatric disease that is associated with neurobiological alterations in multiple brain regions and peripheral organs. Negative symptoms and cognitive deficits are present in about half of patients and are difficult to treat, leading to an unfavorable functional outcome. To investigate the impact of aerobic exercise on various neurobiological parameters, we conducted a narrative review. Add-on aerobic exercise was shown to be effective in improving negative and general symptoms, cognition, global functioning, and quality of life in schizophrenia patients. Based on findings in healthy individuals and animal models, this qualitative review gives an overview of different lines of evidence on how aerobic exercise impacts brain structure and function and molecular mechanisms in patients with schizophrenia and how its effects could be related to clinical and functional outcomes. Structural magnetic resonance imaging studies showed a volume increase in the hippocampus and cortical regions in schizophrenia patients and healthy controls after endurance training. However, results are inconsistent and individual risk factors may influence neuroplastic processes. Animal studies indicate that alterations in epigenetic mechanisms and synaptic plasticity are possible underlying mechanisms, but that differentiation of glial cells, angiogenesis, and possibly neurogenesis may also be involved. Clinical and animal studies also revealed effects of aerobic exercise on the hypothalamus–pituitary–adrenal axis, growth factors, and immune-related mechanisms. Some findings indicate effects on neurotransmitters and the endocannabinoid system. Further research is required to clarify how individual risk factors in schizophrenia patients mediate or moderate the neurobiological effects of exercise on brain and cognition. Altogether, aerobic exercise is a promising candidate in the search for pathophysiology-based add-on interventions in schizophrenia. [ABSTRACT FROM AUTHOR]

Published
2019
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14. A systematic review of trials investigating strength training in schizophrenia spectrum disorders.

Author

Keller-Varady, Katriona, Varady, Patrick A., Röh, Astrid, Schmitt, Andrea, Falkai, Peter, Hasan, Alkomiet, and Malchow, Berend

Subjects
*SCHIZOPHRENIA treatment, *EXERCISE therapy, *STRENGTH training, *PATHOLOGICAL psychology, *SYSTEMATIC reviews, *PSYCHOSES, *MEDLINE, *ONLINE information services, *RESISTANCE training, *THERAPEUTICS
Abstract

This systematic review analyzed strength training (ST) in patients with schizophrenia. Two independent reviewers searched PubMed and CENTRAL. Only two studies reported on the effects of isolated ST. ST with a single exercise did not improve psychopathology but walking performance. ST for several large muscle groups significantly improved muscle strength and psychopathology. To date, no treatment recommendations can be made for ST. Consistent with recommendations for healthy people combined strength and endurance training can be recommended for schizophrenia. For higher transparency regarding trainings aspects, we recommend for future studies to use the sport science checklist proposed in this paper. [ABSTRACT FROM AUTHOR]

Published
2018
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