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182 results on '"Ricard, D."'

20. Evaluation of the psychometric properties of the EORTC chemotherapy-induced peripheral neuropathy questionnaire (QLQ-CIPN20)

Author

Kieffer, Jacobien M., Postma, Tjeerd J., van de Poll-Franse, Lonneke, Mols, Floortje, Heimans, Jan J., Cavaletti, Guido, Aaronson, Neil K., Cavaletti, G., Cornblath, D. R., Merkies, I. S. J., Postma, T. J., Valsecchi, M. G., Galimberti, S., Rossi, E., Cavaletti, G., Frigeni, B., Lanzani, F., Mattavelli, L., Piatti, M. L., Alberti, P., Binda, D., Bidoli, P., Cazzaniga, M., Cortinovis, D., Bruna, J., Velasco, R., Argyriou, A. A., Kalofonos, H. P., Psimaras, D., Ricard, D., Pace, A., Galiè, E., Briani, C., Lucchetta, M., Campagnolo, M., Torre, C. Dalla, Faber, C. G., Merkies, I. S. J., Vanhoutte, E. K., Bakkers, M., Brouwer, B., Boogerd, M., Lalisang, R. I., Boogerd, W., Brandsma, D., Koeppen, S., Hense, J., Grant, R., Storey, D., Kerrigan, S., Schenone, A., Reni, L., Piras, B., Fabbri, S., Pessino, A., Padua, L., Granata, G., Leandri, M., Ghignotti, I., Plasmati, R., Pastorelli, F., Postma, T. J., Heimans, J. J., Eurelings, M., Meijer, R. J., Grisold, W., Pozza, E. Lindeck, Mazzeo, A., Toscano, A., Russo, M., Tomasello, C., Altavilla, G., Prado, M. Penas, Gonzalez, C. Dominguez, Dorsey, S. G., and In Collaboration with the CI-PeriNomS Group

Published
2017
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22. Physician-assessed and patient-reported outcome measures in chemotherapy-induced sensory peripheral neurotoxicity: two sides of the same coin

Author

Cavaletti, G., Cornblath, D.R., Merkies, I.S.J., Postma, T.J., Valsecchi, M.G, Galimberti, S., Rossi, E., Frigeni, B., Lanzani, F., Mattavelli, L., Piatti, M.L., Alberti, P., Binda, D., Bidoli, P., Cazzaniga, M., Cortinovis, D., Bruna, J., Velasco, R., Argyriou, A.A., Kalofonos, H.P., Psimaras, D., Ricard, D., Pace, A., Galiè, E., Briani, C., Lucchetta, M., Campagnolo, M., Dalla Torre, C., Faber, C.G., Vanhoutte, E.K., Bakkers, M., Brouwer, B., Lalisang, R.I., Boogerd, W., Brandsma, D., Koeppen, S., Hense, J., Grant, R., Storey, D., Kerrigan, S., Schenone, A., Reni, L., Piras, B., Fabbri, S., Padua, L., Granata, G., Leandri, M., Ghignotti, I., Plasmati, R., Pastorelli, F., Heimans, J.J., Eurelings, M., Meijer, R.J., Grisold, W., Lindeck Pozza, E., Mazzeo, A., Toscano, A., Tomasello, C., Altavilla, G., Penas Prado, M., Dominguez Gonzalez, C., Dorsey, S.G., Brell, J.M., and Valsecchi, M.G.

Published
2014
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25. Calorimetric Non-Destructive Assay of Large Volume and Heterogeneous Radioactive Waste Drums

Author

Kubinski W. R., Carasco C., Kikola D., Mathonat C., Ricard D., Tefelski D., and Tietze-Jaensch H.

Subjects
Physics, QC1-999
Abstract

The EU-CHANCE project aims at the issue of the characterization of conditioned radioactive waste (CRW) and one objective of CHANCE is to focus on: Calorimetry as a comprising non-destructive technique to reduce uncertainties on the inventory of radwaste containing shielded and hidden material difficult to be measured by other means. A MCNP6-based numerical study comprising the particle flux out of a 200L mock-up drum in a Large Volume Calorimeter (LVC) currently manufactured by KEP Nuclear (France) will be presented and discussed. For the analyses, the particle flux and energy deposition in each layer of the calorimeter were determined. The results yield that a significant fraction of the radiation would leave the system and not contribute to the measurable heat deposition. The expected energy deposition is obtained and cumulated for each layer over the whole energy range revealing the fraction of particles actually escaping the LVC calorimeter. While this escape fraction needs and can be determined, the LVC is a very suitable apparatus for the anticipated experiments on large and heterogeneous waste drums that possibly contain deeply buried beta-emitters (e.g. Sr/Y-90) or shielded alpha-sources hidden inside the drum with a significant level of gamma and neutron radiation background radiation. The high-energy part of this gamma and neutron flux may even reach the reference chamber of the calorimeter and deposit some energy there, compromising the calibration and may cause a double-bias.

Published
2020
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26. Rasch-built Overall Disability Scale for patients with chemotherapy-induced peripheral neuropathy (CIPN-R-ODS)

Author

Galimberti, S., Lanzani, F., Mattavelli, L., Piatti, M.L., Bidoli, P., Cazzaniga, M., Cortinovis, D., Lucchetta, M., Campagnolo, M., Bakkers, M., Brouwer, B., Boogerd, W., Grant, R., Reni, L., Piras, B., Pessino, A., Padua, L., Granata, G., Leandri, M., Ghignotti, I., Plasmati, R., Pastorelli, F., Heimans, J.J., Eurelings, M., Meijer, R.J., Grisold, W., Lindeck Pozza, E., Mazzeo, A., Toscano, A., Russo, M., Tomasello, C., Altavilla, G., Penas Prado, M., Dominguez Gonzalez, C., Dorsey, S.G., Binda, D., Vanhoutte, E.K., Cavaletti, G., Cornblath, D.R., Postma, T.J., Frigeni, B., Alberti, P., Bruna, J., Velasco, R., Argyriou, A.A., Kalofonos, H.P., Psimaras, D., Ricard, D., Pace, A., Galiè, E., Briani, C., Dalla Torre, C., Lalisang, R.I., Brandsma, D., Koeppen, S., Hense, J., Storey, D., Kerrigan, S., Schenone, A., Fabbri, S., Rossi, E., Valsecchi, M.G., Faber, C.G., and Merkies, I.S.J.

Published
2013
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27. The chemotherapy-induced peripheral neuropathy outcome measures standardization study: from consensus to the first validity and reliability findings

Author

Cavaletti, G., Cornblath, D.R., Merkies, I.S.J., Postma, T.J., Rossi, E., Frigeni, B., Alberti, P., Bruna, J., Velasco, R., Argyriou, A.A., Kalofonos, H.P., Psimaras, D., Ricard, D., Pace, A., Galiè, E., Briani, C., Dalla Torre, C., Faber, C.G., Lalisang, R.I., Boogerd, W., Brandsma, D., Koeppen, S., Hense, J., Storey, D., Kerrigan, S., Schenone, A., Fabbri, S., Valsecchi, M.G., Mazzeo, A., Pessino, A., Toscano, A., Brouwer, B., Piras, B., Dominguez Gonzalez, C., Tomasello, C., Binda, D., Cortinovis, D., Lindeck Pozza, E., Vanhoutte, E.K., Lanzani, F., Pastorelli, F., Altavilla, G., Granata, G., Ghignotti, I., Heimans, J.J., Mattavelli, L., Padua, L., Reni, L., Bakkers, M., Boogerd, M., Campagnolo, M., Cazzaniga, M., Eurelings, M., Leandri, M., Lucchetta, M., Penas Prado, M., Russo, M., Piatti, M.L., Bidoli, P., Grant, R., Plasmati, R., Meijer, R.J., Dorsey, S.G., Galimberti, S., and Grisold, W.

Published
2013
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31. Patients' and physicians' interpretation of chemotherapy-induced peripheral neurotoxicity

Author

Cavaletti, G., Cornblath, D. R., Merkies, I. S. J., Postma, T. J., Rossi, E., Alberti, Paola, Bruna, J., Argyriou, A. A., Briani, C., Velasco, Riccardo, Kalofonos, H. P., Psimaras, D., Ricard, D., Pace, A., Faber, C. G., Lalisang, R. I., Brandsma, D., Koeppen, S., Kerrigan, S., Schenone, A., Grisold, W., Mazzeo, A., Padua, L., Dorsey, S. G., Penas-Prado, M., Valsecchi, M. G., Frigeni, B., Lanzani, F., Mattavelli, L., Piatti, M. L., Binda, D., Bidoli, P., Cazzaniga, M., Cortinovis, D., Galie, E., Campagnolo, M., Salvalaggio, A., Ruiz, M., Vanhoutte, E. K., Boogerd, W., Hense, J., Grant, R., Storey, D., Reni, L., Demichelis, C., Pessino, A., Granata, G., Leandri, Martina, Ghigliotti, I., Plasmati, R., Pastorelli, Federica, Heimans, J. J., Eurelings, M., Meijer, R. J., Pozza, E. L., Toscano, A., Gentile, L., Santarpia, M., Gonzalez, C. D., Klinische Neurowetenschappen, MUMC+: MA Med Staf Spec Neurologie (9), RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, Interne Geneeskunde, MUMC+: MA Medische Oncologie (9), RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, MUMC+: DA KG Polikliniek (9), Cavaletti, G, Cornblath, D, Merkies, I, Postma, T, Rossi, E, Alberti, P, Bruna, J, Argyriou, A, Briani, C, Velasco, R, Kalofonos, H, Psimaras, D, Ricard, D, Pace, A, Faber, C, Lalisang, R, Brandsma, D, Koeppen, S, Kerrigan, S, Schenone, A, Grisold, W, Mazzeo, A, Padua, L, Dorsey, S, Penas-Prado, M, Valsecchi, M, Bidoli, P, Cazzaniga, M, Neurology, and CCA - Cancer Treatment and quality of life

Subjects
Adult, medicine.medical_specialty, Activities of daily living, side effect, media_common.quotation_subject, medicine.medical_treatment, assessment, chemotherapy, neurotoxicity, patient reported outcome measures, side effects, Medizin, NEUROPATHY CIPN, Neurological examination, Severity of Illness Index, 03 medical and health sciences, Vibration perception, 0302 clinical medicine, Perception, Internal medicine, Activities of Daily Living, medicine, Humans, VALIDITY, media_common, Oncologists, Neuroscience (all), Neurology (clinical), Chemotherapy, medicine.diagnostic_test, business.industry, General Neuroscience, Neurotoxicity, Outcome measures, Peripheral Nervous System Diseases, assessment, chemotherapy, neurotoxicity, patient reported outcome measures, side effects, Adult, Humans, Neurotoxicity Syndromes, Peripheral Nervous System Diseases, Activities of Daily Living, Oncologists, Patient Reported Outcome Measures, Severity of Illness Index, OUTCOME MEASURES, medicine.disease, Peripheral, patient reported outcome measure, 030220 oncology & carcinogenesis, Neurotoxicity Syndromes, business, 030217 neurology & neurosurgery
Abstract

To test if and how chemotherapy-induced peripheral neurotoxicity (CIPN) is perceived differently by patients and physicians, making assessment and interpretation challenging. We performed a secondary analysis of the CI-PeriNomS study which included 281 patients with stable CIPN. We tested: (a) the association between patients' perception of activity limitation in performing eight common tasks and neurological impairment and (b) how the responses to questions related to these daily activities are interpreted by the treating oncologist. To achieve this, we compared patients' perception of their activity limitation with neurological assessment and the oncologists' blind interpretation. Distribution of the scores attributed by oncologists to each daily life maximum limitation ("impossible") generated three groups: Group 1 included limitations oncologists attributed mainly to motor impairment; Group 2 ones mainly attributed to sensory impairment and Group 3 ones with uncertain motor and sensory impairment. Only a subset of questions showed a significant trend between severity in subjective limitation, reported by patients, and neurological impairment. In Group 1, neurological examination confirmed motor impairment in only 51%-65% of patients; 76%-78% of them also had vibration perception impairment. In Group 2, sensory impairment ranged from 84% to 100%; some degree of motor impairment occurred in 43%-56% of them. In Group 3 strength reduction was observed in 49%-50% and sensory perception was altered in up to 82%. Interpretation provided by the panel of experienced oncologists was inconsistent with the neurological impairment. These observations highlight the need of a core set of outcome measures for future CIPN trials.

Published
2019
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35. Physician-assessed and patient-reported outcome measures in chemotherapy-induced sensory peripheral neurotoxicity: two sides of the same coin

Author

Alberti, P., Rossi, E., Cornblath, D. R., Merkies, I. S. J., Postma, T. J., Frigeni, B., Bruna, J., Velasco, R., Argyriou, A. A., Kalofonos, H. P., Psimaras, D., Ricard, D., Pace, A., Galiè, E., Briani, C., Dalla Torre, C., Faber, C. G., Lalisang, R. I., Boogerd, W., Brandsma, D., Koeppen, S., Hense, J., Storey, D., Kerrigan, S., Schenone, A., Fabbri, S., Valsecchi, M. G., Cavaletti, G., Cavaletti, G., Cornblath, D.R., Merkies, I.S.J., Postma, T.J., Valsecchi, M.G, Galimberti, S., Rossi, E., Cavaletti, G., Frigeni, B., Lanzani, F., Mattavelli, L., Piatti, ML., Alberti, P., Binda, D., Bidoli, P.., Cazzaniga, M., Cortinovis, D., Bruna, J., Velasco, R., Argyriou, AA., Kalofonos, HP., Psimaras, D., Ricard, D., Pace, A., Galiè, E., Briani, C., Lucchetta, M., Campagnolo, M., Dalla Torre, C., Merkies, ISJ., Faber, CG., Merkies, ISJ., Vanhoutte, EK., Bakkers, M., Brouwer, B., Lalisang, RI., Boogerd, W., Brandsma, D., Koeppen, S., Hense, J., Grant, R., Storey, D., Kerrigan, S., Schenone, A., Reni, L., Piras, B., Fabbri, S., Padua, L., Granata, G., Leandri, M., Ghignotti, I., Plasmati, R.., Pastorelli, F., Postma, TJ., Heimans, JJ., Eurelings, M., Meijer, RJ., Grisold, W., Lindeck Pozza, E., Mazzeo, A., Toscano, A., Tomasello, C., Altavilla, G., Penas Prado, M., Dominguez Gonzalez, C., Dorsey, SG., and Brell, JM.

Published
2014
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42. Neurological side effects of radiation therapy.

Author

Jacob, J., Feuvret, L., Simon, J.-M., Ribeiro, M., Nichelli, L., Jenny, C., Ricard, D., Psimaras, D., Hoang-Xuan, K., and Maingon, P.

Subjects
MAGNETIC resonance imaging, QUALITY of life, TUMORS
Abstract

Radiation therapy (RT) is one of the main treatments administered to patients with cancer. The development of technology has improved RT accuracy by allowing more precise delivery of high doses to the target volumes with reduced exposure of healthy tissue. Life expectancy has increased due to these therapeutic advancements and the patients' quality of life remains a major concern. The adverse events related to RT are quite various and most likely will impair essential neurological functions, e.g. cognitive status. This literature review aims to describe the physiopathological processes, the neurological symptoms as well as the local modifications observed in magnetic resonance imaging following RT. The specific therapeutic options and preventive actions will also be discussed. [ABSTRACT FROM AUTHOR]

Published
2022
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45. Correspondence between neurophysiological and clinical measurements of chemotherapy-induced peripheral neuropathy: secondary analysis of data from the CI-PeriNomS study

Author

Griffith, K. A., Dorsey, S. G., Renn, C. L., Zhu, S., Johantgen, M. E., Cornblath, D. R., Argyriou, A. A., Cavaletti, G., Merkies, I. S. J., Alberti, P., Postma, T. J., Rossi, E., Frigeni, B., Bruna, J., Velasco, R., Kalofonos, H. P., Psimaras, D., Ricard, D., Pace, A., Galie, E., Briani, C., Dalla Torre, C., Faber, C. G., Lalisang, R. I., Boogerd, W., Brandsma, D., Koeppen, S., Hense, J., Storey, D. J., Kerrigan, S., Schenone, A., Fabbri, S., Valsecchi, M. G., Galimberti, S., Lucchetta, M., Campagnolo, M., Vanhoutte, E. K., Bakkers, M., Brouwer, B., Grant, R., Reni, L., Piras, B., Lanzani, F., Mattavelli, L., Piatti, M. L., Binda, P., Bidoli, P., Cazzaniga, M., Cortinovis, D., Pessino, A., Padua, L., Granata, G., Leandri, M., Ghignotti, I., Plasmati, R., Pastorelli, F., Heimans, J. J., Eurelings, M., Meijer, R. J., Grisold, W., Lindeck, E., Mazzeo, A., Toscano, A., Russo, M., Tomasello, C., Altavill, G., Penas Prado, M., Dominguez Gonzalez, C., Brell, J., Interne Geneeskunde, RS: CARIM - R3 - Vascular biology, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, RS: GROW - Oncology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Klinische Neurowetenschappen, Griffith, K, Dorsey, S, Renn, C, Zhu, S, Johantgen, M, Cornblath, D, Argyriou, A, Cavaletti, G, Merkies, I, Alberti, P, Postma, T, Rossi, E, Frigeni, B, Bruna, J, Velasco, R, Kalofonos, H, Psimaras, D, Ricard, D, Pace, A, Galie, E, Briani, C, Torre, C, Faber, C, Lalisang, R, Boogerd, W, Brandsma, D, Koeppen, S, Hense, J, Storey, D, Kerrigan, S, Schenone, A, Fabbri, S, Valsecchi, M, Bidoli, P, Neurology, and CCA - Innovative therapy

Subjects
Male, medicine.medical_specialty, peripheral neuropathy, Drug-Related Side Effects and Adverse Reactions, assessment, Medizin, Neural Conduction, Neurophysiology, Action Potentials, Datasets as Topic, Sural nerve, Logistic regression, chemotherapy, Article, Assessment, Chemotherapy, Peripheral neuropathy, Aged, Drug Therapy, Female, Humans, Linear Models, Middle Aged, Pain Measurement, Peripheral Nervous System Diseases, Sural Nerve, Neurologic Examination, Neuroscience (all), Neurology (clinical), Neurofisiologia, Secondary analysis, Quimioteràpia, Medicine, business.industry, General Neuroscience, medicine.disease, Confidence interval, Surgery, Chemotherapy-induced peripheral neuropathy, Anesthesia, Abnormality, neurophysiology, business
Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) lacks standardized clinical measurement. The objective of the current secondary analysis was to examine data from the CIPN Outcomes Standardization (CI-PeriNomS) study for associations between clinical examinations and neurophysiological abnormalities. Logistic regression estimated the strength of associations of vibration, pin, and monofilament examinations with lower limb sensory and motor amplitudes. Examinations were classified as normal (0), moderately abnormal (1), or severely abnormal (2). Among 218 participants, those with class 1 upper extremity (UE) and classes 1 or 2 lower extremity (LE) monofilament abnormality were 2.79 (95% confidence interval [CI]: 1.28-6.07), 3.49 (95%CI: 1.61-7.55), and 4.42 (95%CI: 1.35-14.46) times more likely to have abnormal sural nerve amplitudes, respectively, compared to individuals with normal examinations. Likewise, those with class 2 UE and classes 1 or 2 LE vibration abnormality were 8.65 (95%CI: 1.81-41.42), 2.54 (95%CI: 1.19-5.41), and 7.47 (95%CI: 2.49-22.40) times more likely to have abnormal sural nerve amplitudes, respectively, compared to participants with normal examinations. Abnormalities in vibration and monofilament examinations are associated with abnormal sural nerve amplitudes and are useful in identifying CIPN.

Published
2014
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50. Modernization of Atmospheric Physics Parameterization in Canadian NWP.

Author

McTaggart‐Cowan, R., Vaillancourt, P. A., Zadra, A., Chamberland, S., Charron, M., Corvec, S., Milbrandt, J. A., Paquin‐Ricard, D., Patoine, A., Roch, M., Separovic, L., and Yang, J.

Subjects
ATMOSPHERIC physics, ENERGY budget (Geophysics), NUMERICAL weather forecasting, PARAMETERIZATION
Abstract

Atmospheric physics is represented in numerical models by parameterizations that use resolved‐scale information to estimate the effects of physical processes on the atmospheric state. Over time, our understanding of these processes improves, new techniques are introduced to represent physics in a numerical model, and increased resolution changes the relative importance of different parameterizations within the system. As a result, the physical parameterization packages of numerical weather prediction (NWP) models undergo regular updates as older schemes are replaced with newer ones that offer an improved, and often more complex, depiction of relevant physical processes. Such changes are typically combined with a rebalancing of the physics suite because of strong interactions between parameterization schemes and the presence of compensating errors in the system. In this study, a major update to the package of physical parameterizations used in Canadian operational NWP is introduced. The primary goals of this effort were to improve the global energy budget and to facilitate an increase in the vertical resolution of operational configurations. Both of these objectives were achieved, along with a significant improvement in guidance quality for global and regional prediction systems. Key Points: An updated suite of parameterizations for atmospheric physics is developed for Canadian NWPRepresentation of the global energy budget is improved in the model climatologySignificant improvements in guidance quality are seen in upper‐air, surface, and precipitation scores [ABSTRACT FROM AUTHOR]

Published
2019
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