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Background and purpose: Maternal depression and anxiety can cause nutritional problems in offspring. Despite the numerous literature, the knowledge regarding the impact of maternal mental health on child’s eating disorder is still limited. This study explored the impact of maternal depression and anxiety on eating disorders among children aged 6 to 36 months in Tehran, Iran. Material and Methods: A total number of 320 children aged 6 to 36 months old and their mothers were enrolled at a teaching university hospital in Tehran (Ziaeian Hospital). To collect the data, the inventory of problematic eating behaviors for 36-month old children, Beck Depression Inventory (BDI-II) questionnaire, Beck Anxiety Inventory (BAI) questionnaire, and demographic information questionnaire were used. To examine the relationship between maternal depression and anxiety with childhood feeding problems, bivariate (Chi-square) and multivariate (logistic regression) analyses were employed. Results: The mean mothers’ depression and anxiety scores were found to be 15.97 (SD = 12.08) and 14.26 (SD = 11.87), respectively. An estimated 23.8 % of children were suffering from eating disorders. There was a significant association between the mother’s severe depression and child’s eating disorder [OR = 5.7; CI (95%) = 2.92-11.43]. Although this association attenuated for the moderate level of depression in mothers, it was still statistically significant [OR= 2.25; CI (95%) = 1.05-4.8]. There was also a significant association between the moderate level of anxiety in mother and child’s eating disorder [OR = 2.17; CI (95%) = 1.15-4.10]. Conclusion: It appeared that the children of mothers with higher levels of depression experienced more eating disorders during childhood. Furthermore, middle maternal anxiety level was associated with more feeding abnormalities in children. Therefore, screening and addressing the mental health issues in mothers at the early stages could prevent from future eating disorders in offspring.

Abstract Background Antimicrobial stewardship program (ASP) is a distinguished method to improve the prescription and efficacy of antibiotics. Aim The efficacy of ASP and conventional methods was compared to measure the effectiveness of meropenem (MPM) and vancomycin (VMN) antibiotics in pediatric patients. Design In an interventional quasi-experimental study, 135 children admitted in Children’s Hospital affiliated to University of Medical Sciences in time periods of 2014–2015 and 2015–2016 were assessed. Methods The conventional and ASP methods in 2014–2015 and 2015–2016 were respectively utilized to provide the best antimicrobial therapy of MPM and VMN antibiotics in patient children. The data of mortality rate (MR), antibiotic prescription (AP), antibiotic dose (ADe), antibiotic duration (ADn), length of hospital stay (LOHS), and blood cultures (BCs) were compared across the years using the Chi square, independent t test, and Fisher’s exact test. Results The levels of MR, AP, ADe, ADn, LOHS, and positive BCs using the ASP method in 2015–2016 were significantly lower those of in 2014–2015 using the conventional one (p

Legionella pneumophila is the causative agent of more than 95% cases of severe Legionella pneumonia. Nosocomial pneumonias in different hospital wards is an important medical and pharmaceutical concern. This study aimed to detect Legionella with two methods: polymerase chain reaction [PCR] and detection of urine antigenic test [UAT] in patients suffering from nosocomial pneumonia admitted to pediatric intensive care unit [PICU] of children hospitals. This study was conducted in PICU wards of Rasool Akram and Bahrami children hospitals, Tehran, Iran during 2013 - 2014. In patients diagnosed with hospital-acquired pneumonia, intratracheal secretion samples for PCR and urine sample for urinary antigen test [UTA] were taken. Simultaneously, PCR and urinary antigen test were conducted using commercial kits. The results of urinary antigen test and PCR were analyzed by SPSS v.19 for statistical comparison. In this study, 96 patients aging 2.77 years on average with two age peaks of less than 1 year and 7-8 year were enrolled. More than half of the patients were under 1 year old. The most common underlying diseases were seizure, Acute Lymphoblastic Lymphoma, Down syndrome and metabolic syndromes. The positivity rate of Legionella urinary antigen test was 16.7% and positivity rate of PCR test was 19.8%. There were no significant associations between the results obtained by both assays with age, gender or underlying diseases. In conclusion, PCR is a better detection method for Legionella infection than urinary antigen test, but the difference between the two methods was not significant.