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588 results on '"Sandeep, N."'

14. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials

Author

Cole, Abosede O, Gerstenblith, Adam T, Kotagiri, Ajay, Edwards, Albert O, Zambrano, Alberto D, Eaton, Alexander M, Rubowitz, Alexander, Lyon, Alice T, Chiang, Allen, Ho, Allen, Hu, Allen Y, Guerami, Amir H, Dessouki, Amr L, de Carvalho, André Corrêa Maia, Emanuelli, Andrés, Chang, Andrew A, Antoszyk, Andrew N, Francone, Anibal Andrés, Prasad, Anita, Wolf, Armin, Khanani, Arshad M, Abbey, Ashkan Michael, Moulana, Asma, Wihelm, Barbara, Sikorski, Bartosz L, Kuppermann, Baruch D, Wolff, Benjamin, Jewart, Brian H, Do, Brian K, Chan-Kai, Brian T, Mein, Calvin, Hoyng, Carel B, Awh, Carl C, Regillio, Carl, Zeolite, Carlos, Baumal, Caroline R, Creuzot-Garcher, Catherine, Maury, Catherine Français, Wykoff, Charles C, Newell, Charles K, Jhaveri, Chirag, Lohmann, Chris P, Dinah, Christiana B, Ma, Colin, Crawford, Courtney, Parke, D Wilkin, Lavinsky, Daniel, Roth, Daniel, Pieramici, Dante J, Moshfeghi, Darius M, Levin, Darrin, Saperstein, David A, Brown, David, Gaucher, David, Lally, David R, Liao, David S, Brown, David Warren, Goldstein, Debra, Marcus, Dennis, Chan, Derek G, Dhoot, Dilsher, Tacite, Domingo, Zalewski, Dominik, Espana, Edgar M, Lad, Eleonora M, Souied, Eric H, Suan, Eric P, Eting, Eva, Sola, Federico Furno, de Bats, Flore, Bandello, Francesco, Gómez-Ulla, Francisco, Devin, François, Holz, Frank G, Chen, Fred K, Makkouk, Fuad, Dyer, Gawain, Spital, George, Staurenghi, Giovanni, Stoller, Glenn, Cousins, Gwen, Salehi-Had, Hani, Agostini, Hansjürgen, Eleftheriadis, Haralabos, Weiss, Harold, Sultan, Harris C, Massé, Hélène, Pearce, Ian, Dias, Indra, Barbazetto, Irene, Rosenblatt, Irit, Suñer, Ivan J, Kovach, Jaclyn L, Kaluzny, Jakub, Borthwick, James, Howard, James G, Wong, James, Ernest, Jan, Němčanský, Jan, Ysasaga, Jason Edward, Handza, Jason M, Moreno, Javier Antonio Montero, Korobelnik, Jean-François, Heier, Jeffrey S, Arnold, Jennifer J, Brown, Jeremiah, Bafalluy, Joaquin, Pearlman, Joel, Pitcher, John D, Kitchens, John, Carlson, John P, Gilhotra, Jolly, Fein, Jordana, Monés, Jordi M, Luna, José Domingo, Moreno, José María Ruiz, Coney, Joseph M, Sallum, Juliana Maria Ferraz, Olsen, Karl R, Blobner, Katharina, Macoul, Katherine A, Oh, Kean T, Malik, Khurram Javed, Hattenbach, Lars-Olof, Kodjikian, Laurent, Neto, Laurentino Biccas, Singerman, Lawrence J, Altay, Lebriz, Sheck, Leo-H, Feiner, Leonard, Harris, Lindsey D, Chishold, Lionel D, Rao, Llewelyn J, Nehemy, Márcio Bittar, Elizalde, Maria Jose Capella, Gamulescu, Maria-Andreea, Saravia, Mario J, Johnson, Mark W, McKibbin, Martin, Maccumber, Mathew, Vidosevich, Matko, Ohr, Matthew P, Samuel, Michael A, Singer, Michael A, Cassell, Michael, Dollin, Michael, Elman, Michael J, Ip, Michael S, Goldstein, Michaella, Busquets, Miguel, Mititelu, Mihai, Shah, Milan, Veith, Miroslav, Fineman, Mitchell, Varano, Monica, Christmas, Nancy, Steinle, Nathan C, Chaudhry, Nauman, Chinskey, Nicholas D, Eter, Nicole, London, Nikolas J S, Mathalone, Nurit, Schlottmann, Patricio G, Coady, Patrick, Higgins, Patrick M, Raskauskas, Paul A, Yates, Paul A, Bernstein, Paul, Mitchell, Paul, Monsour, Paul, Raphaelian, Paul V, Stanga, Paulo E, Stodulka, Pavel, Issa, Peter Charbel, Pavan, Peter, Ferrone, Phil J, Oleksy, Piotr, Abraham, Prema, Mruthyunjaya, Prithvi, Nguyen, Quan Dong, Reddy, Rahul K, Khurana, Rahul N, Tuli, Raman, Tadayoni, Ramin, Katz, Randy Steven, Arora, Rashi, Schlingemann, Reinier O, Rosen, Richard B, Gale, Richard, Scartozzi, Richard, Isernharge, Ricky, Singh, Rishi P, Stoltz, Robert A, Avery, Robert L, Wirthlin, Robert S, Guymer, Robyn, Goldberg, Roger A, Frenkel, Ronald, Belfort, Rubens Jr, Mohand-Said, Saddek, Grisanti, Salvatore, Razavi, Sam, Fraser-Bell, Samantha, Shah, Sandeep N, Wickremasinghe, Sanjeewa, Haug, Sara Joy, Adrean, Sean D, Priglinger, Siegfried G, Esposti, Simona Degli, Guest, Stephen, Huddleston, Stephen, Itty, Sujit, Moon, Suk Jin, Bhatia, Sumit P, Gupta, Sunil, Patel, Sunil S, Garg, Sunir J, Joshi, Sunir, Nghiem-Buffet, Sylvia, Johnson, T Mark, Jaouni, Tareq, Ach, Thomas, Williams, Thomas R, Sheidow, Thomas, Cleland, Timothy P, You, Timothy T, Peto, Tunde, Konidaris, Vasileios, Gonzalez, Victor H, Korda, Vladimir, Freeman, William R, Bridges, William Z, Barak, Yoreh, Zagorski, Zbigniew, Yehoshua, Zohar, Dubska, Zora, Rosenfeld, Philip J, Guymer, Robyn H, Boyer, David, Grossi, Federico, Korobelnik, Jean-Francois, Slakter, Jason S, Waheed, Nadia K, Metlapally, Ravi, Steinle, Nathan, Francone, Anibal A, Hu, Allen, Deschatelets, Pascal, Francois, Cedric, Bliss, Caleb, Monés, Jordi, and Ribeiro, Ramiro

Published
2023
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26. MXene (Ti3C2) embedded blood flow on curved stretching artery: Thermal analysis due to nanoparticle shape factor.

Author

Rathore, Niraj, Nabwey, Hossam A., and Sandeep, N.

Subjects
BLOOD flow, NANOPARTICLES, THERMAL analysis, HEAT radiation & absorption, ELECTRIC conductivity, MAGNETISM, PHOTOTHERMAL effect
Abstract

The 2-D MXene material has garnered immense attention in the multidisciplinary region due to its high surface area, excellent electrical conductivity, good biocompatibility, and tunable physicochemical properties. MXene nanoparticles can be utilized in thermal ablation to destroy unwanted tissues and tumors without invasive surgery. Therefore, this work investigates MXene (Ti3C2) embedded blood flow over a curved shape stretching artery. The mathematical model for hybrid blood flow is developed to see the thermal changes due to external pressure and diffusion. Furthermore, the flow model PDEs are equipped with Darcy-Forchheimer's condition, external magnetic force, thermal radiation, and heat source/sink. These PDEs are converted into a system of ODEs by a proper similarity conversion. The solution of governing equations are acquired numerically, the flow and thermal performance outputs are exhibited through pictorial and tabular representations. It is revealed that the thermal performance is enhanced due to sphere shaped MXene (Ti3C2) nanoparticles. The outcomes of this study can be utilized in photothermic therapy and other applications where heat transfer plays an essential role. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Multilevel common‐ground inverter with voltage boosting for PV applications

Author

Sangeeta Kumari, Arun Kumar Verma, Sandeep N, Udaykumar R. Yaragatti, and Hemanshu Roy Pota

Subjects
Solar power stations and photovoltaic power systems, Control of electric power systems, Capacitors, Power convertors and power supplies to apparatus, Electronics, TK7800-8360
Abstract

Abstract Nowadays, transformer‐less Photovoltaic‐based grid‐connected inverters are more popular in renewable energy application due to their reduced size, cost, and high efficiency. However, the absence of galvanic isolation leads to the flow of leakage current in such system hindering personal safety, and deteriorating power quality. Therefore, this paper presents a five‐level transformer‐less inverter topology for PV applications with less component count and reduced complexity. The proposed inverter topology completely eliminates the common mode leakage current. Besides, the proposed topology has an inherent capability to boost the voltage without using any magnetic component or boosting circuit, and is based on the principle of switched/auxiliary capacitor. The proposed topology do not have any limitation of modulation index since the auxiliary capacitors are naturally balanced, hence less complex or no dedicated control scheme is required for balancing/regulating the auxiliary capacitor voltages. In order to verify the performance of the proposed inverter topology, a laboratory prototype is developed which confirms the operation, and feasibility of the proposed inverter. Results depicting the output voltage, load current, and voltage across the auxiliary capacitor are presented for various operating conditions. Further, simulation results depicting the leakage current in the proposed, H5, and H6 topologies are included. Finally, a quantitative comparison study is done, highlighting the benefits of the proposed inverter topology regarding boosted voltage, elimination of leakage current, and reduced component count.

Published
2021
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38. An eight‐switch five‐level inverter with zero leakage current

Author

Sangeeta Kumari, Arun Kumar Verma, Sandeep N, Udaykumar R. Yaragatti, and Hemanshu Roy Pota

Subjects
Power electronics, supply and supervisory circuits, Solar power stations and photovoltaic power systems, Control of electric power systems, Capacitors, Power convertors and power supplies to apparatus, Electronics, TK7800-8360
Abstract

Abstract This paper examines a multilevel transformer‐less grid‐tied inverter topology is proposed for PV applications. Nowadays, transformer‐less inverters are more desirous due to their small filter size, cheaper and higher efficiency. However, the removal of transformer results in the existence of leakage current due to absence of galvanic isolation. The flow of leakage current is the cause of personal safety and deteriorating power quality. A transformer‐less inverter topology is proposed which is able to solve the leakage current issue. Besides, it has the ability to generate the boosted voltage without the need of magnetic component or boosting circuit. It works on the principle of flying/switched capacitor which are able to naturally balance the voltage. Hence, it does not have the limitation of modulation index and no need of complex control scheme to balance or regulate the voltage across an auxiliary capacitor. The performance of the proposed topology is verified by implementing a laboratory prototype which validates the operation and performance of the proposed topology. Results depicting the output voltage, load current and voltage across the auxiliary capacitor are presented for various operating conditions. Moreover, a comprehensive comparison is done, in terms of component count, level and boosting ability of output voltage with leakage current condition.

Published
2021
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42. What is the minimum effective anesthetic volume (MEAV90) of 0.2% ropivacaine required for ultrasound-guided popliteal-sciatic nerve block?

Author

Sandeep N David, Davies C Varghese, and Sebastian Valiaveedan

Subjects
minimum effective anesthetic volume, popliteal-sciatic, ropivacaine, ultrasound, Anesthesiology, RD78.3-87.3, Pharmacy and materia medica, RS1-441
Abstract

Background and Aims: Popliteal-Sciatic nerve block under Ultrasound Guidance (USG) using a local anesthetic agent like Ropivacaine is an established technique for providing analgesia and muscle relaxation for lower limb surgeries with minimal untoward events. Establishing the minimal volume of 0.2% ropivacaine required to provide intraoperative and postoperative analgesia will further reduce the drug requirements and adverse effects toward the patient. Material and Methods: This randomized prospective observational blinded study was done in a tertiary care referral hospital in South India over 9 months from August 2017 till April 2018. The block was performed on all recruited patients under ultrasound guidance with a starting volume of 16 ml 0.2% ropivacaine. Duration of time for loss of pin-prick sensation around the sole of the foot (tibial nerve) and the lateral malleolus (common peroneal nerve) was noted. If successful, the volume of the drug for subsequent patients was randomized by lottery method to either be kept the same or reduced. If the block failed, the subsequent patient recruited would have an increased volume of drug injected. Results: By Probit regression analysis using the biased coin up-and-down method we found that 9.3 ml (MEAV90) of 0.2% ropivacaine was sufficient for providing adequate analgesia. Factors such as patient age or weight had no role in efficacy of the block. There were no adverse effects such as allergy to the drug or systemic toxicity noted in the studied patients. Conclusion: 9.3 ml of 0.2% ropivacaine is sufficient to provide analgesia (assessed by pin-prick) in 90% of patients undergoing popliteal-sciatic block for lower limb surgeries.

Published
2021
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