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Peripllaneta americana are nocturnal animals that transmit typhoid, dysentery, and diarrhea. P. americana is frequently found in filthy environments such as markets, warehouses, and toilets. Apart from that, it is found in bedrooms, bathrooms, kitchens, wardrobes, and even food. Chemical methods have been used to remove cockroaches, but they are hazardous to both human health and the environment. The usage of ecoenzymes derived from nutmeg leaf and pulp waste has great potential as it contains bioactive compounds that can function as bioinsecticides. This research used a completely randomized design with a factorial pattern of 2 × 3 × 3 or 18 treatments, namely, the type of main ingredient (E 1 and E 2), ecoenzyme concentration (K 1, K 2, and K 3), and time after contact (T 1, T 2, and T 3). The measuring parameter in the study was the percentage of cockroach death, which was analyzed using SPSS version 25 for Windows. The results showed that different plant waste’s ecoenzymes also have distinctive colors (E 1 is yellowish brown and E 2 is dark brown), fresh sour smell, pH (E 1 = 3.15 and E 2 = 3.08), temperature (E 1 = 26.4°C and E 2 = 26.03°C), and total dissolved solids (E 1 = 1,263 ppm and E 2 = 1,713 ppm) after fermentation. In addition, there was an effect on cockroaches due to the type of main ingredient, concentration, time after contact, and the interaction of the three on the percentage of mortality of P. americana with LC50 and T50 found in treatments E 2 K 2 T 2 (main ingredient of nutmeg pulp waste, 10% concentration, and time after contact 6 h) and E 2 K 3 T 1 (main ingredient of nutmeg pulp waste, 15% concentration, and time after contact 3 h), so that the resulting ecoenzyme showed positive effects as a potential bioinsecticide of P. americana.

Background: Medication prescribing is essential for the treatment, curing, maintenance, and/or prevention of an illness and disease, however, medication errors remain common. Common errors including prescribing and administration, pose significant risk to patients. Electronic prescribing (e-prescribing) is one intervention used to enhance the safety and quality of prescribing by decreasing medication errors and reducing harm. E-prescribing in community-based settings has not been extensively examined. Objective: To map and characterize the current evidence on e-prescribing and medication safety in community pharmacy settings. Methods: We conducted a rapid scoping review of quantitative, qualitative, and mixed methods studies reporting on e-prescribing and medication safety. MEDLINE All (OVID), Embase (Elsevier), CINAHL Full Text (EBSCOHost), and Scopus (Elsevier) databases were searched December 2022 using keywords and MeSH terms related to e-prescribing, medication safety, efficiency, and uptake. Articles were imported to Covidence and screened by two reviewers. Data were extracted by a single reviewer and verified by a second reviewer using a standardized data extraction form. Findings are reported in accordance with JBI Manual for Evidence Synthesis following thematic analysis to narratively describe results. Results: Thirty-five studies were included in this review. Most studies were quantitative (n = 22), non-experimental study designs (n = 16) and were conducted in the United States (n = 18). Half of included studies reported physicians as the prescriber (n = 18), while the remaining reported a mix of nurse practitioners, pharmacists, and physician assistants (n = 6). Studies reported on types of errors, including prescription errors (n = 20), medication safety errors (n = 9), dispensing errors (n = 2), and administration errors (n = 1). Few studies examined patient health outcomes, such as adverse drug events (n = 5). Conclusions: Findings indicate that most research is descriptive in nature and focused primarily on rates of prescription errors. Further research, such as experimental, implementation, and evaluation mixed-methods research, is needed to investigate the effects of e-prescribing on reducing error rates and improving patient and health system outcomes.

A light guide is an essential part of many scintillator counters and light collection systems. Our main interest is a light guide for a thin, wide scintillator that has high light transmission while converting the area of the light source to the shape of a photo-detector. We propose a variation of the light guide that avoids a 90° twist of the strips, reduces the length of the light pipe, and reduces the complexity of production. Detailed Monte Carlo simulation studies have been performed for a three-strip S-shaped light-guide system. [ABSTRACT FROM AUTHOR]

Abstract Introduction: We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative period. Methods: A retrospective multicenter study including 104 patients who were allocated in three groups according to time of positive real time reverse transcriptase-polymerase chain reaction (RT-PCR) for the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2): group 1, patients who underwent cardiac surgery > 10 days after positive RT-PCR; group 2, patients with a positive RT-PCR within 10 days before or after surgery; group 3, patients who presented positive RT-PCR > 10 days after surgery. The primary outcome was mortality and secondary outcomes were postoperative complications, intensive care unit (ICU) length of stay, and postoperative days of hospitalization. Results: The three groups were similar with respect to age, the European System of Cardiac Operative Risk Evaluation score, and comorbidities, except hypertension. Postoperative complications and death were significantly higher in groups 2 and 3 than in group 1, and no significant difference between groups 2 and 3 was seen. Group 2 showed a high prevalence of surgery performed as an urgent procedure. Although no significant differences were observed in ICU length of stay, total postoperative hospitalization time was significantly higher in group 3 than in groups 1 and 2. Conclusion: COVID-19 affecting the postoperative period of patients who underwent cardiovascular surgery is associated with a higher rate of morbidity and mortality. Delaying procedures in RT-PCR-positive patients may help reduce risks of perioperative complications and death.

Interprofessional collaboration (IPC) in stroke care is accepted as best practice and necessary given the multi-system challenges and array of professionals involved. Our two-part stroke team simulations offer an intentional interprofessional educational experience (IPE) embedded in pre-licensure occupational therapy, physical therapy, pharmacy, medicine, nursing and speech-language pathology curricula. This six-year mixed method program evaluation aimed to determine if simulation delivery differences necessitated by COVID-19 impacted students' IPC perception, ratings, and reported learning. Following both simulations, the Interprofessional Collaborative Competency Assessment Scale (ICCAS) and free-text self-reported learning was voluntarily and anonymously collected. A factorial ANOVA using the ICCAS interprofessional competency factors compared scores across delivery methods. Content and category analysis was done for free-text responses. Overall, delivery formats did not affect positive changes in pre-post ICCAS scores. However, pre and post ICCAS scores were significantly different for interprofessional competencies of roles/responsibilities and collaborative patient/family centered approach. Analysis of over 10,000 written response to four open-ended questions revealed the simulation designs evoked better understanding of others' and own scope of practice, how roles and shared leadership change based on context and client need, and the value of each team member's expertise. Virtual-experience-only students noted preference for an in-person stroke clinic simulation opportunity. [ABSTRACT FROM AUTHOR]

Recently designed dipolar Halbach magnets used in portable MRI systems are much lighter and more compact than standard permanent or superconductive magnets. However, improved designs and manufacturing techniques aiming at lower weight and smaller external size are an area of continual interest especially for application to space flight. Most Halbach magnet design techniques aim to optimize homogeneity suitable for MRI over a diameter-spherical volume (DSV) that requires the aspect ratio (length/inner diameter) to be larger than 1.5:1. Furthermore, current magnet construction techniques often use low-coercivity magnetic pieces and imperfect formers that produce a mismatch in the intended designs. As a result, Halbach magnets require complex shimming methods to improve the magnetic field homogeneity, causing further size and weight increase. Here, we propose to reduce the weight and the aspect ratio of the Halbach magnet by optimizing homogeneity over a cylindrical region of interest (ROI) rather than a DSV, applying a genetic algorithm, high-coercivity ferromagnets (N40UH) and a robust construction technique. The assembled 67 mT magnet, with aspect ratio ~ 1:1, produces almost identical homogeneity (11152 ppm) as simulations (11451 ppm) within a 12.7 cm diameter, 1 cm long cylinder ROI. The magnet structure was 3D printed ring-by-ring and assembled coaxially. The magnet can be disassembled for transportation.

Peserta dalamkegiatan ini adalah masyarakat yang tergolong dalam Kelompok Wanita Tani (KWT) Kartini Mandiri yang berada di Kelurahan Parauna Kecamatan Anggaberi Kabupaten Konawe. Berdasarkan tujuan dari kegiatan pelatihan pengolahan komoditas labu kuning yaitu memperkenalkan dan memberikan pengetahuan dan keterampilan tambahan kepada masyarakat tentang teknologi pengolahan labu kuning menjadi dodol labu kuning dan roti kasur sehingga masyarakat dapat mengembangkan industri rumah tangga dan meningkatkan nilai ekonomis dari labu kuning dengan memberikan penyuluhan tentang manfaat dari labu kuning disertai dengan pelatihan dan praktek membuat dodol dan roti kasur dari labu kuning. Pengolahan dodol dan roti kasur dengan aneka variasi isian merupakan inovasi baru di Kelurahan Parauna. Keberhasilan pelaksanaan seluruh kegiatan pengabdian kepada masyarakat ini tentunya mempunyai manfaat yang cukup baik bagi masyarakat pada umumnya dan pelaku industri rumah tangga khususnya.

We report the first large-acceptance measurement of the beam–spin asymmetry for deuteron photodisintegration (γ→d→pn) in the photon energy range 420

THE INNOVATION People experiencing homelessness (PEH) face an elevated burden of chronic and communicable disease, mental health and substance use disorders, and unmet health and support needs. (1-2) Health and [...]

The beam-helicity asymmetry was measured, for the first time, in photoproduction of π0η pairs on carbon, aluminum, and lead, with the A2 experimental setup at MAMI. The results are compared to an earlier measurement on a free proton and to the corresponding theoretical calculations. The Mainz model is used to predict the beam-helicity asymmetry for the nuclear targets. The present results indicate that the photoproduction mechanism for π0η pairs on nuclei is similar to photoproduction on a free nucleon. This process is dominated by the D33 partial wave with the ηΔ(1232) intermediate state.

The helicity-dependent cross sections for the photoproduction of π0η pairs have been measured for the first time. The experiment was performed at the tagged photon facility of the Mainz MAMI accelerator with the combined Crystal Ball – TAPS calorimeter. The experiment used a polarized deuterated butanol target and a circularly polarized photon beam. This arrangement allowed the σ1/2 (photon and target spin antiparallel) and σ3/2 (parallel spins) components to be measured for quasi-free production of π0η pairs off protons and neutrons. The main finding is that the two helicity components contribute identically, within uncertainties, for both participant protons and neutrons. The absolute couplings for protons and neutrons are also identical. This means that nucleon resonances contributing to this reaction in the investigated energy range have almost equal electromagnetic helicity couplings, A1/2n,p and A3/2n,p. Identical couplings for protons and neutrons are typical for Δ resonances and identical A1/2 and A3/2 components are only possible for J≥3/2 states, which constrains possible contributions of nucleon resonances.

This research aims to reveal the dynamics of social, economic, and cultural changes in agribusiness institutions in oil palm development locations. Then reveal the role of each agribusiness institution in oil palm development locations. Using a qualitative approach to build a post-positivism approach. The research location is limited to the community (farmers) in Anggabaeri District and Besulutu District, Konawe Regency. These two research areas were chosen purposively. The database used in determining farmer groups is groups that are active and registered in the Extension Information System or SIMLUH data so 22 informants were obtained consisting of farmer group institutions, cooperative institutions, and government agencies, as well as from the Agricultural Extension Center. Specifically for farmers, the informants selected consisted of independent and plasma farmers. Data was obtained by distributing questionnaires and interviews and then analyzed descriptively. The results of the analysis show that from a social, economic, and cultural perspective, the presence of oil palm plantations brings significant changes. These changes include shifts in social stratification, interaction patterns, and improvements in health status. Apart from that, the regional economic structure is also undergoing a transformation which has an impact on increasing the income of various communities such as workers and farmers. Then there is the role of institutions, especially farmer groups, and cooperatives, in supporting and facilitating farmers' interests as a learning vehicle, production unit, and collaboration forum. Extension institutions play an important role in increasing farmers' capacity, and cooperatives contribute significantly to the provision of production facilities, transportation, and marketing of crops. An important finding is the important role of cooperatives in managing various risks associated with oil palm farming. These risks include business, financial, social, and legal engineering aspects. Cooperatives play an important role in mitigating these risks and ensuring the overall well-being and success of their members. [ABSTRACT FROM AUTHOR]

A key part of the contemporary “Russia challenge” is the West’s tendency to misread that country, both its capacity for reform and the West’s own impact on the choices that have shaped its trajectory. Excess faith in the power of the market and the applicability of social science theories skewed Western policy toward Russia in the 1990s, fuelling the xenophobic and nationalistic narratives that laid the foundations of Putinism. Misreading Russia’s historical insecurities after the collapse of the USSR ensured that US triumphalism would play badly in Moscow, contributing to the toxic environment amidst which Putin ultimately opted to invade Ukraine. None of this justifies the recent excesses of the Putin regime, but it does help to make them intelligible. Appreciating how the West has misread and mismanaged Russia in the past should contribute to more realistic and more effective approaches in the future. [ABSTRACT FROM AUTHOR]

The double-polarization observable E and the helicity-dependent cross sections σ1/2 and σ3/2 have been measured for the first time for single π0 photoproduction from protons and neutrons bound in the deuteron at the electron accelerator facility MAMI in Mainz, Germany. The experiment used a circularly polarized photon beam and a longitudinally polarized deuterated butanol target. The reaction products, recoil nucleons and decay photons from the π0 meson were detected with the Crystal Ball and TAPS electromagnetic calorimeters. Effects from nuclear Fermi motion were removed by a kinematic reconstruction of the π0N final state. A comparison to data measured with a free proton target showed that the absolute scale of the cross sections is significantly modified by nuclear final-state interaction (FSI) effects. However, there is no significant effect on the asymmetry E since the σ1/2 and σ3/2 components appear to be influenced in a similar way. Thus, the best approximation of the two helicity-dependent cross sections for the free neutron is obtained by combining the asymmetry E measured with quasi-free neutrons and the unpolarized cross section corrected for FSI effects under the assumption that the FSI effects are similar for neutrons and protons.

Quantitative proteins analysis was carried out in the hypothalamus of zebrafish following dietary exposure to the legacy pesticide dieldrin. Data were collected using iTRAQ labeling methodology and data were acquired using a hybrid quadrupole Orbitrap (Q Exactive) MS system (Thermo Fisher Scientific, Bremen, Germany). There were 3941 proteins identified in the hypothalamus of zebrafish, and these proteins comprised 23 unique expression patterns for proteins based on the three doses of dieldrin. There were 226 proteins that were regulated in one or more doses of dieldrin and 3715 proteins that were not affected. Thus, 5.7% of the proteins detected responded to the treatment. Many proteins that were differentially expressed were those found in, or associated with, the mitochondria. The proteomics data described in this article is associated with a research article, “Transcriptomic and proteomic analysis implicates the immune system and mitochondria as molecular targets of dieldrin in the zebrafish (Danio rerio) central nervous system” (A.M. Cowie, K.I. Sarty, A. Mercer, J. Koh, K.A. Kidd, C.J. Martyniuk, submitted) [1], and serves as a resource for researchers working in the field of pesticide exposures and protein biomarkers.

We report on new p(e,e′p)π∘ measurements at the Δ+(1232) resonance at the low momentum transfer region, where the mesonic cloud dynamics is predicted to be dominant and rapidly changing, offering a test bed for chiral effective field theory calculations. The new data explore the Q2 dependence of the resonant quadrupole amplitudes and for the first time indicate that the Electric and the Coulomb quadrupole amplitudes converge as Q2→0. The measurements of the Coulomb quadrupole amplitude have been extended to the lowest momentum transfer ever reached, and suggest that more than half of its magnitude is attributed to the mesonic cloud in this region. The new data disagree with predictions of constituent quark models and are in reasonable agreement with dynamical calculations that include pion cloud effects, chiral effective field theory and lattice calculations. The measurements indicate that improvement is required to the theoretical calculations and provide valuable input that will allow their refinements.

Polarisation-dependent differential cross sections σT associated with the target asymmetry T have been measured for the reaction γp→→pπ0 with transverse target polarisation from π0 threshold to photon energies of 190 MeV. The data were obtained using a frozen-spin butanol target with the Crystal Ball / TAPS detector set-up and the Glasgow photon tagging system at the Mainz Microtron MAMI. Results for σT have been used in combination with our previous measurements of the unpolarised cross section σ0 and the beam asymmetry Σ for a model-independent determination of S- and P-wave multipoles in the π0 threshold region, which includes for the first time a direct determination of the imaginary part of the E0+ multipole.

AbstractObjective:Report initial experience with the Frozen Elephant Trunk technique.Methods:From July 2009 to October 2013, Frozen Elephant Trunk technique was performed in 21 patients (66% male, mean age 56 ±11 years). They had type A aortic dissection (acute 9.6%, chronic 57.3%), type B (14.3%, all chronic) and complex aneurysms (19%). It was 9.5% of reoperations and 38% of associated procedures (25.3% miocardial revascularization, 25.3% replacement of aortic valve and 49.4% aortic valved graft). Aortic remodeling was evaluated comparing preoperative and most recent computed tomography scans. One hundred per cent of complete follow-up, mean time of 28 months.Results:In-hospital mortality of 14.2%, being 50% in acute type A aortic dissection, 8.3% in chronic type A aortic dissection, 33.3% in chronic type B aortic dissection and 0% in complex aneurysms. Mean times of cardiopulmonary bypass (152±24min), myocardial ischemia (115±31min) and selective cerebral perfusion (60±15min). Main complications were bleeding (14.2%), spinal cord injury (9.5%), stroke (4.7%), prolonged mechanical ventilation (4.7%) and acute renal failure (4.7%). The need for second-stage operation was 19%. False-lumen thrombosis was obtained in 80%.Conclusion:Frozen Elephant Trunk is a feasible technique and should be considered. The severity of the underlying disease justifies high mortality rates. The learning curve is a reality. This approach allows treatment of more than two segments at once. Nonetheless, if a second stage is made necessary, it is facilitated.

The aim of this work is to combine behavioural and functional magnetic resonance imaging (fMRI) data to advance our knowledge of where the Frequency x Regularity interaction on word naming is located in the cerebral cortex. Participants named high and low frequency, regular and exception words in a behavioural lab (Experiment 1) and during an fMRI study (Experiment 2). We used the Additive Factors Method (AFM) to localize the expected overadditive Frequency x Regularity interaction both temporally, through word naming reaction times (whereby low frequency exceptions produce the longest reaction times), and spatially on the cortex, through hemodynamic response measures from fMRI (whereby low frequency exceptions produce the highest activation intensities). Activation maps revealed significant activation for low frequency exception words in the supplementary motor association cortex (SMA). We interpret the SMA activation as increased articulatory preparation, given previous demonstrations of the SMA's involvement in motor programming. Hemodynamic time courses were extracted from four regions of interest: the middle temporal gyri, SMA, insula and the inferior frontal gyri. Importantly, hemodynamic intensities within the SMA displayed an overadditive interaction pattern parallel to that found with naming reaction times. Thus, we provide an application of the AFM to fMRI intensity measures and evidence that the SMA is a potential cortical source of the Frequency x Regularity interaction during a basic naming paradigm. While the AFM has traditionally been used to localize factors in time we provide evidence that the AFM is useful in understanding how variables influence one another in the brain. (Contains 1 table and 7 figures.)

Previous functional magnetic resonance imaging (fMRI) studies have investigated the role of phonological processing by utilizing nonword rhyming decision tasks (e.g., Pugh et al., 1996). Although such tasks clearly engage phonological components of visual word recognition, it is clear that decision tasks are more cognitively involved than the simple overt naming tasks, which more closely map onto normal reading behavior. Our research aim for this study was to examine the advantages of overt naming tasks for fMRI studies of word recognition processes. Process models are presented to highlight the similarities and differences between two cognitive tasks that are used in the word recognition literature, pseudohomophone naming (e.g., pronounce BRANE) and rhyming decision (e.g., do LEAT and JEAT rhyme?). An fMRI study identified several differences in cortical activation associated with the differences observed in the process models. Specifically, the results show that the overt naming task involved the insular cortex and inferior frontal gyrus, whereas the rhyming decision task engaged the temporal-parietal regions. It is argued that future fMRI research examining the neuroanatomical components of basic visual word recognition utilize overt naming tasks.