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357 results on '"Sato, Ryota"'

7. STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes

Author

Kuchitsu, Yoshihiko, Mukai, Kojiro, Uematsu, Rei, Takaada, Yuki, Shinojima, Ayumi, Shindo, Ruri, Shoji, Tsumugi, Hamano, Shiori, Ogawa, Emari, Sato, Ryota, Miyake, Kensuke, Kato, Akihisa, Kawaguchi, Yasushi, Nishitani-Isa, Masahiko, Izawa, Kazushi, Nishikomori, Ryuta, Yasumi, Takahiro, Suzuki, Takehiro, Dohmae, Naoshi, Uemura, Takefumi, Barber, Glen N., Arai, Hiroyuki, Waguri, Satoshi, and Taguchi, Tomohiko

Published
2023
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18. Validation of the obesity paradox by body mass index and waist circumference in patients undergoing percutaneous coronary intervention

Author

Shirahama, Yuichiro, Tabata, Noriaki, Sakamoto, Kenji, Sato, Ryota, Yamanaga, Kenshi, Fujisue, Koichiro, Sueta, Daisuke, Araki, Satoshi, Takashio, Seiji, Arima, Yuichiro, Hokimoto, Seiji, Sato, Koji, Sakamoto, Tomohiro, Nakao, Koichi, Shimomura, Hideki, Matsumura, Toshiyuki, Tayama, Shinji, Fujimoto, Kazuteru, Oshima, Shuichi, Nakamura, Shinichi, Tsunoda, Ryusuke, Hirose, Toyoki, Kikuta, Koichi, Sakaino, Naritsugu, Yamamoto, Nobuyasu, Kajiwara, Ichiro, Suzuki, Satoru, Yamamoto, Eiichiro, Kaikita, Koichi, Matsushita, Kenichi, and Tsujita, Kenichi

Published
2022
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23. Impact of cerebrovascular comorbidity on prognosis in Japanese patients undergoing PCI: 1-year data from Japanese multicenter registry (KICS)

Author

Ahmed, Khlood, Arima, Yuichiro, Tabata, Noriaki, Ishii, Masanobu, Sato, Ryota, Yamashita, Takayoshi, Yamanaga, Kenshi, Takizawa, Hitoshi, Hokimoto, Seiji, Sueta, Daisuke, Araki, Satoshi, Fujisue, Koichiro, Takashio, Seiji, Fujimoto, Kazuteru, Shimomura, Hideki, Tsunoda, Ryusuke, Hirose, Toyoki, Sato, Koji, Kikuta, Koichi, Sakaino, Naritsugu, Nakamura, Shinichi, Yamamoto, Nobuyasu, Matsumura, Toshiyuki, Kajiwara, Ichiro, Tayama, Shinji, Sakamoto, Tomohiro, Nakao, Koichi, Oshima, Shuichi, Yamamoto, Eiichiro, Sakamoto, Kenji, Kaikita, Koichi, Matsushita, Kenichi, and Tsujita, Kenichi

Published
2022
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29. Temperature dependence of photoluminescence spectrum of single lead halide perovskite nanocrystals: Effect of size on the phase transition temperature.

Author

Cho, Kenichi, Yamada, Takumi, Saruyama, Masaki, Sato, Ryota, Teranishi, Toshiharu, and Kanemitsu, Yoshihiko

Subjects
PHASE transitions, TRANSITION temperature, LEAD halides, SEMICONDUCTOR nanocrystals, PHOTOLUMINESCENCE, NANOCRYSTALS, LEAD-free ceramics
Abstract

Photoluminescence (PL) spectroscopy of individual semiconductor nanocrystals (NCs) is a powerful method for understanding the intrinsic optical properties of these materials. Here, we report the temperature dependence of the PL spectra of single perovskite FAPbBr3 and CsPbBr3 NCs [FA = HC(NH2)2]. The temperature dependences of the PL linewidths were mainly determined by the Fröhlich interaction between excitons and longitudinal optical phonons. For FAPbBr3 NCs, a redshift in the PL peak energy appeared between 100 and 150 K, which was because of the orthorhombic-to-tetragonal phase transition. We found that the phase transition temperature of FAPbBr3 NCs decreases with decreasing NC size. [ABSTRACT FROM AUTHOR]

Published
2023
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30. Temporal trends in coronary intervention strategies and the impact on one-year clinical events: data from a Japanese multi-center real-world cohort study

Author

Sakamoto, Kenji, Sato, Ryota, Tabata, Noriaki, Ishii, Masanobu, Yamashita, Takayoshi, Nagamatsu, Suguru, Motozato, Kota, Yamanaga, Kenshi, Hokimoto, Seiji, Sueta, Daisuke, Araki, Satoshi, Fujisue, Koichiro, Arima, Yuichiro, Takashio, Seiji, Fujimoto, Kazuteru, Shimomura, Hideki, Tsunoda, Ryusuke, Hirose, Toyoki, Sato, Koji, Kikuta, Koichi, Sakaino, Naritsugu, Nakamura, Shinichi, Yamamoto, Nobuyasu, Matsumura, Toshiyuki, Kajiwara, Ichiro, Tayama, Shinji, Sakamoto, Tomohiro, Nakao, Koichi, Oshima, Shuichi, Yamamoto, Eiichiro, Kaikita, Koichi, and Tsujita, Kenichi

Published
2022
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31. Evolution of fractal patterns in lead-free zero-dimensional perovskite Cs2InBr5(H2O).

Author

Ge, Wanyin, Yang, Maohao, Saruyama, Masaki, Matsumoto, Kenshi, Sato, Ryota, Takekuma, Haruka, Takahata, Ryo, and Teranishi, Toshiharu

Subjects
LIQUID crystals, PEROVSKITE, X-ray diffraction, NUCLEATION, CRYSTALLIZATION, GLASS-ceramics
Abstract

The crystallization behavior of halide perovskites is of great significance. Fractal structures, featured by self-similarity between local morphology and global structures, have consistently captivated scientists' interest across diverse disciplines. In this study, we realized the fractal patterns in lead-free zero-dimensional (0D) Cs2InBr5(H2O) perovskites. By depositing saturated precursor droplets on silicon or glass substrates, we initiated nucleation and crystallization of 0D Cs2InBr5(H2O) crystals on the liquid's upper surface. As the solution evaporated, the remaining high-concentration solution formed self-similar fractal patterns beneath the Cs2InBr5(H2O) crystals. This anisotropic growth mechanism imparted a unique self-assembly behavior to 0D Cs2InBr5(H2O). Additionally, X-ray diffraction results confirmed distinct preferential orientations of the fractal patterns. The findings of this work provide valuable insights into the controlled crystallization behavior of lead-free perovskites and inspire further exploration of novel optoelectronic properties arising from such a unique fractal pattern. [ABSTRACT FROM AUTHOR]

Published
2024
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32. Epoxide Ring‐Opening Reactions for Abundant Production of Mugineic Acids and Nicotianamine Probes.

Author

Kayano, Kimika, Tsutsumi, Tomohiro, Murata, Yoshiko, Ogasa, Chie, Watanabe, Takehiro, Sato, Ryota, Karanjit, Sangita, and Namba, Kosuke

Subjects
RING-opening reactions, OXIDATION-reduction reaction, ACIDS, OVUM
Abstract

A succinct synthetic approach to mugineic acids and 2'‐hydroxynicotianamine was established. Unlike all other synthetic methods, this approach utilized epoxide ring‐opening reactions to form two C−N bonds and is characterized by the absence of redox reactions. Mugineic acid was synthesized from three readily available fragments on a gram scale in 6 steps. The protected 2'‐hydroxynicotianamine was also synthesized in 4 steps, and the dansyl group, serving as a fluorophore, was introduced through a click reaction after propargylation of the 2'‐hydroxy group. The dansyl‐labeled nicotianamine (NA) iron complexes were internalized by oocytes overexpressing ZmYS1 (from maize) or PAT1 (from human) transporters, indicating successful transport of the synthesized NA‐probe through these transporters. [ABSTRACT FROM AUTHOR]

Published
2024
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36. IgG Fc sialylation is regulated during the germinal center reaction following immunization with different adjuvants

Author

Bartsch, Yannic C., Eschweiler, Simon, Leliavski, Alexei, Lunding, Hanna B., Wagt, Sander, Petry, Janina, Lilienthal, Gina-Maria, Rahmöller, Johann, de Haan, Noortje, Hölscher, Alexandra, Erapaneedi, Raghu, Giannou, Anastasios D., Aly, Lilian, Sato, Ryota, de Neef, Louise A., Winkler, André, Braumann, Dominique, Hobusch, Juliane, Kuhnigk, Kyra, Krémer, Vanessa, Steinhaus, Moritz, Blanchard, Véronique, Gemoll, Timo, Habermann, Jens K., Collin, Mattias, Salinas, Gabriela, Manz, Rudolf A., Fukuyama, Hidehiro, Korn, Thomas, Waisman, Ari, Yogev, Nir, Huber, Samuel, Rabe, Björn, Rose-John, Stefan, Busch, Hauke, Berberich-Siebelt, Friederike, Hölscher, Christoph, Wuhrer, Manfred, and Ehlers, Marc

Published
2020
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38. Aberrant monocytopoiesis drives granuloma development in sarcoidosis.

Author

Hiranuma, Ryosuke, Sato, Ryota, Yamaguchi, Kiyoshi, Nakamizo, Satoshi, Asano, Kenichi, Shibata, Takuma, Fukui, Ryutaro, Furukawa, Yoichi, Kabashima, Kenji, and Miyake, Kensuke

Subjects
*SARCOIDOSIS, *GRANULOMA, *PROGENITOR cells, *DENDRITIC cells, *MACROPHAGE activation
Abstract

In sarcoidosis, granulomas develop in multiple organs including the liver and lungs. Although mechanistic target of rapamycin complex 1 (mTORC1) activation in macrophages drives granuloma development in sarcoidosis by enhancing macrophage proliferation, little is known about the macrophage subsets that proliferate and mature into granuloma macrophages. Here, we show that aberrantly increased monocytopoiesis gives rise to granulomas in a sarcoidosis model, in which Tsc2, a negative regulator of mTORC1, is conditionally deleted in CSF1R-expressing macrophages (Tsc2 csf1rΔ mice). In Tsc2 csf1rΔ mice, common myeloid progenitors (CMPs), granulocyte-monocyte progenitors (GMPs), common monocyte progenitors / monocyte progenitors (cMoPs / MPs), inducible monocyte progenitors (iMoPs), and Ly6Cint CX3CR1low CD14− immature monocytes (iMOs), but not monocyte-dendritic cell progenitors (MDPs) and common dendritic cell progenitors (CDPs), accumulated and proliferated in the spleen. Consistent with this, monocytes, neutrophils, and neutrophil-like monocytes increased in the spleens of Tsc2 csf1rΔ mice, whereas dendritic cells did not. The adoptive transfer of splenic iMOs into wild-type mice gave rise to granulomas in the liver and lungs. In these target organs, iMOs matured into Ly6Chi classical monocytes/macrophages (cMOs). Giant macrophages (gMAs) also accumulated in the liver and lungs, which were similar to granuloma macrophages in expression of cell surface markers such as MerTK and SLAMF7. Furthermore, the gMA-specific genes were expressed in human macrophages from sarcoidosis skin lesions. These results suggest that mTORC1 drives granuloma development by promoting the proliferation of monocyte/neutrophil progenitors and iMOs predominantly in the spleen, and that proliferating iMOs mature into cMOs and then gMAs to give rise to granuloma after migration into the liver and lungs in sarcoidosis. [ABSTRACT FROM AUTHOR]

Published
2024
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39. Intrinsic Visible Plasmonic Properties of Colloidal PtIn2 Intermetallic Nanoparticles.

Author

Takekuma, Haruka, Sato, Ryota, Iida, Kenji, Kawawaki, Tokuhisa, Haruta, Mitsutaka, Kurata, Hiroki, Nobusada, Katsuyuki, and Teranishi, Toshiharu

Subjects
*SURFACE plasmon resonance, *PLASMONICS, *FACE centered cubic structure, *COPPER, *NANOPARTICLES
Abstract

Materials that intrinsically exhibit localized surface plasmon resonance (LSPR) in the visible region have been predominantly researched on nanoparticles (NPs) composed of coinage metals, namely Au, Ag, and Cu. Here, as a coinage metal‐free intermetallic NPs, colloidal PtIn2 NPs with a C1 (CaF2‐type) crystal structure are synthesized by the liquid phase method, which evidently exhibit LSPR at wavelengths similar to face‐centered cubic (fcc)‐Au NPs. Computational simulations pointed out differences in the electronic structure and photo‐excited electron dynamics between C1‐PtIn2 and fcc‐Au NPs; reduces interband transition and stronger screening with smaller number of bound d‐electrons compare with fcc‐Au are unique origins of the visible plasmonic nature of C1‐PtIn2 NPs. These results strongly indicate that the intermetallic NPs are expected to address the development of alternative plasmonic materials by tuning their crystal structure and composition. [ABSTRACT FROM AUTHOR]

Published
2024
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40. An overlapping case of IgG4-related disease and systemic lupus erythematosus treated with belimumab: a case-based review.

Author

Iwamoto, Megumi, Asashima, Hiromitsu, Sugita, Toshiki, Kawashima, Fumina, Sugita, Naoki, Rai, Akiyoshi, Kuroda, Yuki, Kawashima, Akira, Tabuchi, Daiki, Akao, Satoshi, Sato, Ryota, Nishiyama, Taihei, Toko, Hirofumi, Honda, Fumika, Ohyama, Ayako, Kitada, Ayako, Abe, Saori, Miki, Haruka, Hagiwara, Shinya, and Kondo, Yuya

Subjects
TALL-1 (Protein), BELIMUMAB, PLASMA cells, DNA antibodies, ANTINUCLEAR factors
Abstract

IgG4-related disease (IgG4-RD) is a systemic condition in which IgG4+ plasma cell infiltration and fibrosis cause organ swelling and lead to diverse clinical manifestations. Although IgG4-RD typically responds to glucocorticoids (GCs), relapse during tapering occurs and an early GC-sparing approach might therefore be beneficial. Systemic lupus erythematosus (SLE) is a chronic inflammatory disease with multiple symptoms that is also treated with GCs as a first-line therapy. Recently, belimumab, a recombinant human IgG-1λ monoclonal antibody that inhibits B-cell activating factor, was approved, but reports of use for IgG4-RD are scarce. Here, we present a rare case of IgG4-RD complicated with SLE which was successfully treated with belimumab. A 67-year-old man was diagnosed with IgG4-RD based on a high serum IgG4 level and histopathological findings. Furthermore, he had pericardial effusion on echocardiography, and laboratory tests revealed thrombocytopenia, autoimmune hemolysis, positive anti-nuclear antibodies, positive anti-DNA antibodies, and hypocomplementemia. These data led to an SLE diagnosis. Treatment was started with prednisolone at 40 mg/day, plus hydroxychloroquine, which initially improved both the SLE and IgG4-RD symptoms. During the GC tapering, belimumab was added and clinical symptoms resolved completely. Our case and the literature review summarize reported rare overlapping cases of IgG4-RD and SLE and suggest that belimumab is a promising candidate for the treatment of IgG4-RD. [ABSTRACT FROM AUTHOR]

Published
2024
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