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[No abstract available] Funding Agencies|Flinders University; RU, Radboud Universiteit; NIU, Northern Illinois University; University of Nottingham; Universität zu Köln; Charité – Universitätsmedizin Berlin; SLU, Saint Louis University; TU/e, Technische Universiteit Eindhoven; University of Leeds; IUPUI, Indiana University-Purdue University Indianapolis; UiT, Universitetet i Tromsø; EUR, Erasmus Universiteit Rotterdam; UvT, Universiteit van Tilburg; University of Oxford; UNIL, Université de Lausanne; SEBM, Society for Experimental Biology and Medicine; NYU, New York University; UiT, Universitetet i Tromsø; RWTH Aachen University; KU Leuven; Universität Bielefeld; University of Louisiana at Lafayette; UA, University of Arkansas; Genentech Foundation for Biomedical Sciences; University of Bristol; UV, University of Virginia; City of Mobile; Université de Fribourg; Universiteit Gent; Yale University; VT, Virginia Polytechnic Institute and State University; DIBS, Duke Institute for Brain Sciences, Duke University; UCB UK; University of Leeds; BIBS, Brown Institute for Brain Science; UU, Universiteit Utrecht; Keele University; HRD, Division of Human Resource Development; WVU, West Virginia University; King’s College London; NTU, Nottingham Trent University; Rijksuniversiteit Groningen; KACST, King Abdulaziz City for Science and Technology; University of Edinburgh; UCONN, University of Connecticut; University of Kent; University of Cambridge; UNLV, University of Nevada, Las Vegas; Universiteit Leiden; UBC, University of British Columbia; HGS, Human Genome Sciences; AV CR, Akademie Ved Ceské Republiky; IUPUI, Indiana University-Purdue University Indianapolis; UK, University of Kentucky; University of Texas at Austin; DRS, Dahlem Research School, Freie Universität Berlin; Bangor University; RAND Corporation; University of Glasgow; University of Chester; CONICET, Consejo Nacional de Investigaciones Científicas y Técnicas; Massey University; UC, University of California; NIH, National Institutes of Health; UFSC, Universidade Federal de Santa Catarina; OU, Open University; Electroencephalography and Clinical Neuroscience Society; UNAB, Universidad Autónoma de Bucaramanga; KACST, King Abdulaziz City for Science and Technology; SU, Stanford University; CSIR, Council for Scientific and Industrial Research; FSU, Florida State University; UW, University of Wisconsin-Madison; LUMC, Leids Universitair Medisch Centrum; CERSI, Center of Excellence in Regulatory Science and Innovation; DePaul University; Baylor University; SU, Sahlgrenska Universitetssjukhuset; NINDS, National Institute of Neurological Disorders and Stroke

Mucormycosis is the second most common cause of invasive mould infection and causes disease in diverse hosts, including those who are immuno-competent. We conducted a multicentre retrospective study of proven and probable cases of mucormycosis diagnosed between 2004-2012 to determine the epidemiology and outcome determinants in Australia. Seventy-four cases were identified (63 proven, 11 probable). The majority (54.1%) were caused by Rhizopus spp. Patients who sustained trauma were more likely to have non-Rhizopus infections relative to patients without trauma (OR 9.0, p 0.001, 95% CI 2.1-42.8). Haematological malignancy (48.6%), chemotherapy (42.9%), corticosteroids (52.7%), diabetes mellitus (27%) and trauma (22.9%) were the most common co-morbidities or risk factors. Rheumatological/autoimmune disorders occurred in nine (12.1%) instances. Eight (10.8%) cases had no underlying co-morbidity and were more likely to have associated trauma (7/8; 87.5% versus 10/66; 15.2%; p

Introduction The objective is to evaluate the diagnosis of foreign body (FB) ingestion and report on the endoscopic management in Taiwan. Methods This retrospective study enrolled 159 adult patients with confirmed diagnosis of upper gastrointestinal FBs who received endoscopic management in the emergency department. Results The patients’ mean age was 57.0 ± 19.2 years, and 66 (37.7%) of the patients were 65 years or older. Majority had a clear history and symptoms of FB ingestion. However, 9 (5.7%) initially ignored the accidental swallowing of FBs and were diagnosed late. The mean time spent for diagnosis was 1.8 days in those with uncertain history. Only 47.1% of those with radiographic studies had positive findings. Fish bones, press-through package and dentures were the most common culprits in this population of Asian elderly. Majority of FBs were located in the esophagus, especially in the upper third. Endoscopic FB extraction was successful in 96.9% of cases, while surgery was required in only 5 patients. The complication rate was 6.9%, including mucosal laceration (n = 10) and suspected perforation (n = 1), all of which were successfully managed conservatively. There was no death due to FB ingestion or endoscopy. Conclusions In FB ingestion, history usually points toward the diagnosis. Patients with an uncertain history are usually diagnosed late, and plain radiography cannot reliably predict the presence of FB. Endoscopic management is safe and effective for FBs.