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2 results on '"Stulle, M."'

1. P517: PROSPECTIVE MULTICENTRIC STUDY ON INFECTIOUS COMPLICATIONS AND CLINICAL OUTCOME IN 230 UNFIT AML PATIENTS TREATED IN FIRST‐LINE WITH HYPOMETHYLATING AGENTS ALONE OR IN COMBINATION WITH VENETOCLAX.

Author

Candoni, A., Piccini, M., Lazzarotto, D., Bonuomo, V., Dargenio, M., Riva, M., Mellillo, L., Papayannidis, C., Stulle, M., Dragonetti, G., Del Principe, M. I., Cattaneo, C., Pasciolla, C., De Marchi, R., Delia, M., Tisi, M. C., Zannier, M. E., Nadali, G., Sciumè, M., and Spadea, A.

Published
2022
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2. Higher total ghrelin levels are associated with higher insulin-mediated glucose disposal in non-diabetic maintenance hemodialysis patients

Author

Maria Pia Mucci, Manuela Stulle, Gianfranco Guarnieri, Michela Zanetti, Gianni Biolo, A. Pirulli, Giovanni Panzetta, Rocco Barazzoni, A. Vasile, Franca Dore, Barazzoni, Rocco, Zanetti, Michela, Stulle, M., Mucci, M. P., Pirulli, Alessia, Dore, Franca, Panzetta, G., Vasile, A., Biolo, Gianni, and Guarnieri, Gianfranco

Subjects
Adult, Blood Glucose, Male, medicine.medical_specialty, medicine.medical_treatment, Critical Care and Intensive Care Medicine, Systemic inflammation, insulin resistance, inflammation, ghrelin, chronic kidney disease, Insulin resistance, Renal Dialysis, Diabetes mellitus, Internal medicine, medicine, Humans, Insulin, Resting energy expenditure, Pancreatic hormone, Aged, Nutrition and Dietetics, business.industry, digestive, oral, and skin physiology, Middle Aged, Glucose clamp technique, medicine.disease, C-Reactive Protein, Endocrinology, Case-Control Studies, Glucose Clamp Technique, Linear Models, Kidney Failure, Chronic, Female, Ghrelin, Basal Metabolism, medicine.symptom, business, hormones, hormone substitutes, and hormone antagonists
Abstract

BACKGROUND & AIMS: Insulin resistance is common in maintenance hemodialysis (MHD) and it can contribute to exceedingly high mortality in MHD patients. Ghrelin is a gastric hormone whose total plasma concentration is increased in MHD. Emerging data suggest a potential role of ghrelin to modulate intermediate metabolism but the metabolic impact of ghrelin in chronic kidney disease is unknown. The current study aimed at assessing the potential relationships between ghrelin and insulin sensitivity in MHD. METHODS: Total (T-Ghr) and acylated (A-Ghr) ghrelin as well as insulin-mediated glucose disposal [(M): hyperinsulinemic-euglycemic clamp] were measured in non-diabetic non-obese ambulatory MHD patients (n=19, 16 Males). C-reactive protein (CRP) was also measured since systemic inflammation is associated with insulin resistance in non-renal patients and inflammation is negatively modulated by ghrelin in experimental models. RESULTS: Compared to control subjects (C: n=9, 7 Males), MHD had similar body fat and resting energy expenditure but reduced M and increased CRP (P

Published
2008
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