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1. Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in the adult hippocampus of male mice

Author

Bielefeld, P., Martirosyan, A., Martín-Suárez, S., Apresyan, A., Meerhoff, G. F., Pestana, F., Poovathingal, S., Reijner, N., Koning, W., Clement, R. A., Van der Veen, I., Toledo, E. M., Polzer, O., Durá, I., Hovhannisyan, S., Nilges, B. S., Bogdoll, A., Kashikar, N. D., Lucassen, P. J., Belgard, T. G., Encinas, J. M., Holt, M. G., and Fitzsimons, C. P.

Published
2024
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11. Understanding vortex dynamics in CaK(Fe,Ni)4As4 and Ba(Fe,Co)2As2 single crystals under the influence of random point disorder.

Author

Haberkorn, N, Xu, M, Schmidt, J, Suárez, S, Bud'Ko, S L, and Canfield, P C

Subjects
SUPERCONDUCTING transition temperature, MAGNETIC transitions, IRON-based superconductors, MAGNETIC flux density, SINGLE crystals
Abstract

We report on the influence of doping on vortex dynamics in 3 MeV proton-irradiated single crystals of CaK(Fe1− x Ni x)4As4 (1144, x = 0.015, 0.025, and 0.03) and Ba(Fe1− x Co x)2As2 (x = 0.04, 0.062, 0.066 and 0.074). Non-irradiated crystals of the 1144 system display superconducting critical temperatures ranging from 31 K for x = 0.015–20.5 K, as doping increases to 0.03. On the other hand, pristine crystals of the 122 system show Tc values between 14.6 and 23.6 K, with the maximum Tc occurring at intermediate doping levels. The fluence was set at 3 × 1016 p cm−2, resulting in a decrease in the Tc by around 1.5 K for all samples and significantly affecting the vortex dynamics by reducing the flux creep relaxation compared to previously reported values for unirradiated crystals. Parameters such as vortex pinning energy U 0 and the glassy exponent μ dependencies on doping and magnetic field strength are identified. For the 1144 system, U 0 reaches values approaching 500 K for small fields in samples with Tc = 29.3 K (x = 0.015), systematically decreasing to around 200 K as Tc falls below 20 K. Furthermore, U 0 decreases as the field increases to 3 T for the same sample, varying from approximately 250 K to 100 K as Tc decreases. These changes are typically accompanied by modifications in μ, gradually increasing from values around 1 towards 1.5, corresponding to small bundle relaxation in the collective creep theory. Despite differences in the substitutional disorder and magnetic phase diagram with respect to the 1144 system, the results for 122 single crystals follow a similar tendency in which U 0 usually reduces and μ increase rise as the applied magnetic field is increased. Due to moderate U 0 in these systems (few hundreds of kelvins), the resulting decay of persistent current at liquid helium temperatures is primarily determined by a balance between U 0 and bundle size contribution. These findings provide valuable insights for potential applications of these systems, particularly in the context of intrinsic superconducting parameters and the resulting pinning landscape. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Comparative clinical prognosis of massive and non‐massive pulmonary embolism: A registry‐based cohort study

Author

Blondon, Marc, Jimenez, David, Robert‐Ebadi, Helia, Del Toro, Jorge, Lopez‐Jimenez, Luciano, Falga, Conxita, Skride, Andris, Font, Llorenç, Vazquez, Fernando Javier, Bounameaux, Henri, Monreal, Manuel, Prandoni, Paolo, Brenner, Benjamin, Farge‐Bancel, Dominique, Barba, Raquel, Di Micco, Pierpaolo, Bertoletti, Laurent, Schellong, Sebastian, Tzoran, Inna, Reis, Abilio, Bosevski, Marijan, Malý, Radovan, Verhamme, Peter, Caprini, Joseph A, My Bui, Hanh, Adarraga, MD, Agud, M, Aibar, J, Aibar, MA, Alfonso, J, Amado, C, Arcelus, JI, Baeza, C, Ballaz, A, Barba, R, Barbagelata, C, Barrón, M, Barrón‐Andrés, B, Blanco‐Molina, A, Botella, E, Camon, AM, Castro, J, Caudevilla, MA, Cerdà, P, Chasco, L, Criado, J, de Ancos, C, de Miguel, J, Demelo‐Rodríguez, P, Díaz‐Peromingo, JA, Díez‐Sierra, J, Díaz‐Simón, R, Domínguez, IM, Encabo, M, Escribano, JC, Falgá, C, Farfán, AI, Fernández‐Capitán, C, Fernández‐Reyes, JL, Fidalgo, MA, Flores, K, Font, C, Francisco, I, Gabara, C, Galeano‐Valle, F, García, MA, García‐Bragado, F, García‐Mullor, MM, Gavín‐Blanco, O, Gavín‐Sebastián, O, Gil‐Díaz, A, Gómez‐Cuervo, C, González‐Martínez, J, Grau, E, Guirado, L, Gutiérrez, J, Hernández‐Blasco, L, Jara‐Palomares, L, Jaras, MJ, Jiménez, D, Joya, MD, Jou, I, Lacruz, B, Lecumberri, R, Lima, J, Lobo, JL, López‐Brull, H, López‐Jiménez, L, López‐Miguel, P, López‐Núñez, JJ, López‐Reyes, R, López‐Sáez, JB, Lorente, MA, Lorenzo, A, Loring, M, Madridano, O, Maestre, A, Marchena, PJ, Martín del Pozo, M, Martín‐Martos, F, Martínez‐Baquerizo, C, Mella, C, Mellado, M, Mercado, MI, Moisés, J, Morales, MV, Muñoz‐Blanco, A, Muñoz‐Guglielmetti, D, Muñoz‐Rivas, N, Nart, E, Nieto, JA, Núñez, MJ, Olivares, MC, Ortega‐Michel, C, Ortega‐Recio, MD, Osorio, J, Otalora, S, Otero, R, Parra, P, Parra, V, Pedrajas, JM, Pellejero, G, Pérez‐Jacoiste, A, Peris, ML, Pesántez, D, Porras, JA, Portillo, J, Reig, L, Riera‐Mestre, A, Rivas, A, Rodríguez‐Cobo, A, Rodríguez‐Matute, C, Rogado, J, Rosa, V, Rubio, CM, Ruiz‐Artacho, P, Ruiz‐Giménez, N, Ruiz‐Ruiz, J, Ruiz‐Sada, P, Sahuquillo, JC, Salgueiro, G, Sampériz, A, Sánchez‐Muñoz‐Torrero, JF, Sancho, T, Sigüenza, P, Sirisi, M, Soler, S, Suárez, S, Suriñach, JM, Tiberio, G, Torres, MI, Tolosa, C, Trujillo‐Santos, J, Uresandi, F, Usandizaga, E, Valle, R, Vela, JR, Vidal, G, Vilar, C, Villares, P, Zamora, C, Gutiérrez, P, Vázquez, FJ, Vanassche, T, Vandenbriele, C, Verhamme, P, Hirmerova, J, Malý, R, Salgado, E, Benzidia, I, Bertoletti, L, Bura‐Riviere, A, Crichi, B, Debourdeau, P, Espitia, O, Farge‐Bancel, D, Helfer, H, Mahé, I, Moustafa, F, Poenou, G, Schellong, S, Braester, A, Brenner, B, Tzoran, I, Amitrano, M, Bilora, F, Bortoluzzi, C, Brandolin, B, Ciammaichella, M, Colaizzo, D, Dentali, F, Di Micco, P, Giammarino, E, Grandone, E, Mangiacapra, S, Mastroiacovo, D, Maida, R, Mumoli, N, Pace, F, Pesavento, R, Pomero, F, Prandoni, P, Quintavalla, R, Rocci, A, Siniscalchi, C, Tufano, A, Visonà, A, Vo Hong, N, Zalunardo, B, Kalejs, RV, Maķe, K, Ferreira, M, Fonseca, S, Martins, F, Meireles, J, Bosevski, M, Zdraveska, M, Mazzolai, L, Caprini, JA, Tafur, AJ, Weinberg, I, Wilkins, H, and Bui, HM

Published
2021
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23. Alternatives for the administration of oral antineoplastics in patients with swallowing difficulties.

Author

Tejedor Tejada, E., Gonzalez Suárez, S., Lizondo López, T., López-Cabezas, C., and Soy Muner, D.

Abstract

Abstract\nImplications for the PracticeOncology patients often experience swallowing difficulties, which can compromise adherence to treatment and consequently reduce its effectiveness. Improper handling of these hazardous drugs can lead to the risk of inhalation of particles or other exposures endangering the health of the persons involved such as nurses and pharmacists. The aim of this review is to analyse and update the recommendations for the manipulation of oral antineoplastic drugs in patients with swallowing difficulties. A literature review of articles, websites, guidelines and other documents published up to about the conditions of handling and administration of oral antineoplastic agents in oncology and oncohaematology was carried out. A table of 110 active principles was compiled. The information was grouped according to the name of the drug, instructions for oral and nasogastric tube administration and suggested recommendations. Among the drugs reviewed, 66.4% were suitable for dissolution. Although there is a lot of information in the literature, the nonstop development of new oncological drugs requires continuous updating. Therefore, we have collected the most recent data to provide a consultation tool for healthcare professionals and patients with swallowing difficulties.This review can be used by all types of healthcare professionals, especially nurses, who handle oncological medicinal drugs. In addition, the safest handling methods for the worker have been recommended. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Biomasa de raíces finas en arreglos agroforestales con cacao en la amazonia occidental colombiana

Author

Adrián Rico A. and Juan Carlos Suárez S.

Subjects
Agroforestería, Theobroma, Sistema radical, Densidad aparente, Suelo, Agriculture, Agriculture (General), S1-972
Abstract

Los arreglos agroforestales con cacao poseen una estructura diversificada, la cual influye sobre el comportamiento de las raíces finas, cuya distribución está influenciada por las diferentes prácticas culturales. El objetivo del presente trabajo fue estudiar la distribución, el aporte de biomasa de raíces finas en relación con la densidad aparente y el porcentaje de humedad en arreglos agroforestales con cacao en el Centro de Investigaciones CIMAZ Macagual (1°37’LN y 75°36’LO). El muestreo se desarrolló en tres arreglos agroforestales con cacao clasificados en sombra intensa, semisombra y pleno sol. Para la extracción de la biomasa de raíces se utilizó el cilindro de volumen conocido cada 10cm hasta llegar a 1m de profundidad. Las raíces finas fueron extraídas a través de una malla de un tamaño

Published
2018
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49. Incidence of Vasoplegic Syndrome during Liver Transplantation and Patient Outcomes.

Author

González-Suárez, S., Dammala, I. M., Grao, M., and Camio, E.

Subjects
*CENTRAL venous pressure, *GRAFT rejection, *SEPTIC shock, *LIVER transplantation, *VASCULAR resistance
Abstract

Background: The incidence of vasoplegic syndrome during liver transplantation is unknown, and it is occasionally confused with postreperfusion syndrome, which is another similar form of hemodynamic instability. In these cases, monitoring patients with the Swan-Ganz catheter may be useful for differential diagnosis. Objective: The main outcome was the incidence of vasoplegic syndrome or postreperfusion syndrome in the patients, and the prognosis of patients with vasoplegic syndrome was the secondary outcome. Methods: This retrospective study included 246 consecutive orthotopic liver transplantation procedures performed in patients aged >18 years who were monitored using a Swan-Ganz catheter. Vasoplegic syndrome was defined as mean arterial pressure <50 mmHg, pulmonary capillary wedge pressure =15 mmHg, central venous pressure <5 mmHg, cardiac index >2.5 L/min/m2, systemic vascular resistance <800 dyn/s/cm-5, and increased heart rate and mean pulmonary arterial pressure from the baseline (anhepatic phase). The estimated marginal means and their 95% confidence intervals were determined for the total sample. Results: Of the 246 patients, only two (0.81%) developed vasoplegic syndrome after unclamping the portal vein. Another patient (0.40%) showed the hemodynamic features of vasoplegic syndrome but was diagnosed with septic shock due to positive blood culture. One patient with vasoplegic syndrome presented with postoperative renal failure and graft rejection, requiring another liver transplantation, and the other patient did not survive. Conclusion: Most episodes of hemodynamic instability after liver graft reperfusion are due to postreperfusion syndrome, and the occurrence of vasoplegic syndrome is very rare and is associated with poor prognosis. [ABSTRACT FROM AUTHOR]

Published
2023

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