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3. Expression of Estrogen and Progesterone Receptors in the Endometrium, Myometrium and Vagina of Postmenopausal Women.

Author

Beata, S., Romanowicz-Makowska, H., Szyllo, K., Krajewska, W. M., and Kulig, A.

Subjects
ESTROGEN, SEX hormones, STEROID hormones, GENE expression, MESSENGER RNA, PROGESTATIONAL hormones
Abstract

Estriol is an estrogen with considerably weaker stimulatory effects on endometrial proliferation than estradiol. A study was conducted to determine the effects of 14-day vaginal estriol therapy on the mRNA level of estrogen (ER) and progesterone receptors (PRs). In the estriol treated patients in comparison to the control group a significant increase of ER gene expression was observed in the endometrium and vagina while PR gene expression enhancement was found in the endometrium.

Published
2004

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