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4. Persistence of immunity 18–19 years after vaccination against hepatitis B in 2 cohorts of vaccinees primed as infants or as adolescents in Italy

Author

Romanò, Luisa, Galli, Cristina, Tagliacarne, Catia, Tosti, Maria Elena, Velati, Claudio, Fomiatti, Laura, Chironna, Maria, Coppola, Rosa Cristina, Cuccia, Mario, Mangione, Rossana, Marrone, Fosca, Negrone, Francesco Saverio, Parlato, Antonino, Zotti, Carla Maria, Mele, Alfonso, Zanetti, Alessandro Remo, Spada, Enea, Alfonsi, Valeria, Sallustio, Anna, Procacci, Rossella, Masia, Giuseppina, Meloni, Angelo, Grande, Silvana Lo, Filippo, Cantone, Gonfalone, Vito, Consagra, Rosa Maria, Russotto, Angela, Frangapani, Domenico, Ulivieri, Giovanna, Nini, Alessandra, Maldini, Morena, Cafarelli, Giuseppe, Giambersio, Antonio, Alfieri, Rosa, Santolo, Milena Scotto di, Zamparo, Emanuela, Cacello, Elena, Montu’, Domenico, and Belloni, Annamaria

Subjects
Male, 0301 basic medicine, Secondary, Pediatrics, HBsAg, Time Factors, Booster dose, immune memory, Group A, Group B, 0302 clinical medicine, HBV, Immunology and Allergy, Medicine, 030212 general & internal medicine, Young adult, biology, virus diseases, Hepatitis B, Research Papers, Vaccination, Italy, Female, Antibody, long-term immunity, hepatitis B, vaccination, Adolescent, Adult, Hepatitis B Antibodies, Hepatitis B Vaccines, Humans, Infant, Young Adult, Immunization, Secondary, Immunologic Memory, Immunology, Pharmacology, medicine.medical_specialty, 030106 microbiology, complex mixtures, 03 medical and health sciences, Internal medicine, business.industry, medicine.disease, digestive system diseases, biology.protein, Immunization, business
Abstract

This study was aimed at assessing the anti-HBs persistence and immune memory 18–19 y after vaccination against hepatitis B in healthy individuals primed as infants or adolescents. We enrolled 405 teenagers (Group A) vaccinated as infants, and 409 young adults (Group B) vaccinated as adolescents. All vaccinees were tested for anti-HBs and anti-HBc antibodies; those found anti-HBc positive were further tested for HBsAg and HBV DNA. Eight individuals belonging to Group B were positive for anti-HBc alone, and were excluded from analysis. Individuals with anti-HBs concentration ≥ 10 mIU/ml were considered protected while those with anti-HBs concentration

Published
2017
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6. Phylogeography and phylodynamics of European genotype 3 hepatitis E virus.

Author

Zehender, Gianguglielmo, Ebranati, Erika, Lai, Alessia, Luzzago, Camilla, Paladini, Sara, Tagliacarne, Catia, Galli, Cristina, Galli, Massimo, Ciccozzi, Massimo, Zanetti, Alessandro R., and Romanò, Luisa

Subjects
*PHYLOGEOGRAPHY, *HEPATITIS E virus, *POPULATION dynamics, *EPIDEMIOLOGY, *ZOONOSES
Abstract

Highlights: [•] Phylogeny and phylodynamics of the human and swine HEV genotype 3. [•] Location of origin and pathways of global dispersion of HEV genotype 3. [•] Population dynamics of HEV genotype 3 epidemic. [•] Hypotheses on the eco/epidemiological causes leading to the zoonotic global spread of HEV. [Copyright &y& Elsevier]

Published
2014
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