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• Vestibular changes in altered gravity and their morphological basis are discussed. • Behavioural correlations of vestibular abnormalities are provided. • Gecko and mice vestibular cerebellum in the Bion-M and Foton-M experiments are widely reviewed. • Bion-M1experiments provided evidence for the sensory compensation hypothesis. In humans and other vertebrates, the range of disturbances and behavioural changes induced by spaceflight conditions are well known. Sensory organs and the central nervous system (CNS) are forced to adapt to new environmental conditions of weightlessness. In comparison with peripheral vestibular organs and behavioural disturbances in weightlessness conditions, the CNS vestibular centres of vertebrates, including the cerebellum, have been poorly examined in orbital experiments, as well as in experimental micro- and hypergravity. However, the cerebellum serves as a critical control centre for learning and sensory system integration during space-flight. Thus, it is referred to as a principal brain structure for adaptation to gravity and the entire sensorimotor adaptation and learning during weightlessness. This paper is focused on the prolonged spaceflight effects on the vestibular cerebellum evidenced from animal models used in the Bion-M1 project. The changes in the peripheral vestibular apparatus and brainstem primary vestibular centres with appropriate behavioural disorders after altered gravity exposure are briefly reviewed. The cerebellum studies in space missions and altered gravity are discussed. [ABSTRACT FROM AUTHOR]

Reptiles are a rare model object for space research. However, some reptile species demonstrate effective adaptation to spaceflight conditions. The main scope of this review is a comparative analysis of reptile experimental exposure in weightlessness, demonstrating the advantages and shortcomings of this model. The description of the known reptile experiments using turtles and geckos in the space and parabolic flight experiments is provided. Behavior, skeletal bones (morphology, histology, and X-ray microtomography), internal organs, and the nervous system (morphology, histology, and immunohistochemistry) are studied in the spaceflight experiments to date, while molecular and physiological results are restricted. Therefore, the results are discussed in the scope of molecular data collected from mammalian (mainly rodents) specimens and cell cultures in the parabolic and orbital flights and simulated microgravity. The published data are compared with the results of the gecko model studies after the 12−44.5-day spaceflights with special reference to the unique peculiarities of the gecko model for the orbital experiments. The complex study of thick-toed geckos after three spaceflights, in which all geckos survived and demonstrated effective adaptation to spaceflight conditions, was performed. However, future investigations are needed to study molecular mechanisms of gecko adaptation in space.

Proper characterisation of the survivability of an unmanned spacecraft to debris impact must go beyond just a simple assessment of the probability of penetration. Some penetrative damage may be survivable, particularly if critical internal equipment is arranged judiciously. Consideration of the satellite architecture can be seen as a potentially cost-effective and complementary approach to the more traditional method of adding shielding mass. To quantify the benefits of both strategies, and identify candidate protection solutions for a typical satellite design, a new model called SHIELD has been developed. Competing protection options are evaluated using a survivability metric. Rapid convergence on one or more `good'' designs can also be achieved with a built-in genetic algorithm search method. SHIELD''s potential as a project support tool is illustrated by applying it to the survivability evaluation of a satellite currently under design. The effectiveness of the genetic algorithm is also demonstrated, but on a more idealised spacecraft design. [Copyright &y& Elsevier]

PlanetNet algorithm has helped scientists to understand a storm on the giant planet. PlanetNet algorithm has helped scientists to understand a storm on the giant planet., Author Affiliations: Machine learning has helped researchers to find and map ammonia-rich clouds at the centre of a storm on Saturn. [see PDF for image] Credit: NASA/JPL/Space Science Institute Image [...]

Human space flight represents a heady mix of bravery and drama which can be inspirational to nations and to humankind but at huge economic cost. Due to the current high launch costs only a handful of people have ventured beyond low Earth orbit and walked on the Moon, propelled by aspirations related more to the Cold War than to science. Problems with reusable launch vehicle development mean that severe launch cost limitations will exist for some time. Meanwhile, cheaper robotic probes have visited all the planets except Pluto, flown by comets, landed on Mars, Venus and an asteroid, have probed Jupiter's atmosphere and studied the Universe beyond our own solar system with telescopes. Using these data we are determining mankind's place in the Universe. Public interest in the historic Eros landing eclipsed a simultaneous space walk at the fledgling International Space Station and the Mars Pathfinder landing generated hundreds of millions of website hits in a few days. Given the fact that hundreds of Mars missions could be flown for the still-escalating cost of the International Space Station, the unsuitability of human bodies for deep space exploration, and the advances in 3-d and virtual reality techniques, we discuss whether human exploration needs a place in a realistic, useful and inspirational space programme. [ABSTRACT FROM AUTHOR]

Reptiles are a rare model object for space research. However, some reptile species demonstrate effective adaptation to spaceflight conditions. The main scope of this review is a comparative analysis of reptile experimental exposure in weightlessness, demonstrating the advantages and shortcomings of this model. The description of the known reptile experiments using turtles and geckos in the space and parabolic flight experiments is provided. Behavior, skeletal bones (morphology, histology, and X-ray microtomography), internal organs, and the nervous system (morphology, histology, and immunohistochemistry) are studied in the spaceflight experiments to date, while molecular and physiological results are restricted. Therefore, the results are discussed in the scope of molecular data collected from mammalian (mainly rodents) specimens and cell cultures in the parabolic and orbital flights and simulated microgravity. The published data are compared with the results of the gecko model studies after the 12–44.5-day spaceflights with special reference to the unique peculiarities of the gecko model for the orbital experiments. The complex study of thick-toed geckos after three spaceflights, in which all geckos survived and demonstrated effective adaptation to spaceflight conditions, was performed. However, future investigations are needed to study molecular mechanisms of gecko adaptation in space. [ABSTRACT FROM AUTHOR]