Search

Your search keyword '"Wang, Kaituo"' showing total 228 results
Start Over Author "Wang, Kaituo" Search Limiters Peer Reviewed
228 results on '"Wang, Kaituo"'

4. Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate

Author

Vidal-Calvo, Elena Ethel, Martin-Salazar, Anne, Choudhary, Swati, Dagil, Robert, Raghavan, Sai Sundar Rajan, Duvnjak, Lara, Nordmaj, Mie Anemone, Clausen, Thomas Mandel, Skafte, Ann, Oberkofler, Jan, Wang, Kaituo, Agerbæk, Mette Ø, Løppke, Caroline, Jørgensen, Amalie Mundt, Ropac, Daria, Mujollari, Joana, Willis, Shona, Garcias López, Agnès, Miller, Rebecca Louise, Karlsson, Richard Torbjörn Gustav, Goerdeler, Felix, Chen, Yen-Hsi, Colaço, Ana R., Wang, Yong, Lavstsen, Thomas, Martowicz, Agnieszka, Nelepcu, Irina, Marzban, Mona, Oo, Htoo Zarni, Ørum-Madsen, Maj Sofie, Wang, Yuzhuo, Nielsen, Morten A., Clausen, Henrik, Wierer, Michael, Wolf, Dominik, Gögenur, Ismail, Theander, Thor G., Al-Nakouzi, Nader, Gustavsson, Tobias, Daugaard, Mads, and Salanti, Ali

Published
2024
Full Text
View/download PDF

31. VOZ‐dependent priming of salicylic acid‐dependent defense against Rhizopus stolonifer by β‐aminobutyric acid requires the TCP protein TCP2 in peach fruit.

Author

Wang, Kaituo, Li, Chunhong, Cao, Shifeng, Lei, Changyi, Ji, Nana, Zou, Yanyu, Tan, Meilin, Wang, Jinsong, Zheng, Yonghua, and Gao, Haiyan

Subjects
*VASCULAR plants, *TRANSCRIPTION factors, *SALICYLIC acid, *GENE expression, *DISEASE resistance of plants
Abstract

SUMMARY Vascular plant one‐zinc finger (VOZ) transcription factors (TFs) play crucial roles in plant immunity. Nevertheless, how VOZs modulate defense signaling in response to elicitor‐induced resistance is not fully understood. Here, the defense elicitor β‐aminobutyric acid (BABA) resulted in the visible suppression of Rhizopus rot disease of peach fruit caused by Rhizopus stolonifer. Defense priming by BABA was notably associated with increased levels of salicylic acid (SA) and SA‐dependent gene expression. Data‐independent acquisition proteomic analysis revealed that two VOZ proteins (PpVOZ1 and PpVOZ2) were substantially upregulated in BABA‐induced resistance (BABA‐IR). Furthermore, the interaction of PpVOZ1 and PpVOZ2 and their potential target of the TEOSINTE‐BRANCHED1/CYCLOIDEA/PCF (TCP)‐family protein PpTCP2 screened from protein–protein interaction networks was confirmed by yeast two‐hybrid (Y2H), luciferase complementation imaging and glutathione S‐transferase pull‐down assays. Furthermore, subcellular localization, yeast one‐hybrid, electrophoretic mobility shift assay and dual‐luciferase reporter assays demonstrated that nuclear localization of both PpVOZ1 and PpVOZ2 was critical for their contribution to BABA‐IR, as these proteins potentiated the PpTCP2‐mediated transcriptional activation of isochorismate synthase genes (ICS1/2). The overexpression of both PpVOZ1 and PpVOZ2 could activate the transcription of SA‐dependent genes and provide disease resistance in transgenic Arabidopsis. In contrast, the ppvoz1cas9 and ppvoz2cas9 loss‐of‐function mutations and the voz1cas9 voz2cas9 double mutation attenuated BABA‐IR against R. stolonifer. Therefore, the three identified positive TFs, PpVOZ1, PpVOZ2, and PpTCP2, synergistically contribute to the BABA‐activated priming of systemic acquired resistance in postharvest peach fruit by a VOZ‐TCP‐ICS regulatory module. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

32. Study on Mechanical Characteristics of Discontinuous Cut-Off Wall of Dam Foundation Based on Plastic Damage Calculation Method.

Author

Fang, Dinghan, Wang, Kaituo, Xu, Shuochang, and Wang, Xingchen

Subjects
EARTH dams, DAM safety, STREAMFLOW, CONCRETE walls, COMPUTER simulation
Abstract

Dam foundations are prone to leakage damage after being exposed to long-term water action, which seriously affects the operation safety of the dam. At present, concrete cut-off walls serve an important means of anti-seepage for dam foundations. However, due to construction challenges, the cut-off wall needs to be poured segment-by-segment during the construction process, and the joints between adjacent segments become weak parts for seepage prevention. Therefore, it is crucial to clarify the stress state of segmented discontinuous concrete cut-off walls. Based on the Lee-Fenves framework and the tension–compression constitutive relationship of fracture energy, a plastic damage calculation method was established in this paper to characterize the mechanical behavior of discontinuous cut-off walls. The method was then used to analyze the mechanical performance of discontinuous walls with segment joints containing slurry cake. The research results showed that compared to the continuous cut-off wall, the vertical settlement in the middle part of the discontinuous cut-off wall increased by 5.8%, and the displacement along the river flow direction decreased by 35.3%. As the wall segment width decreased, the joint opening and the degree of tensile damage were reduced accordingly, while the compressive damage in the middle and lower parts of the wall was intensified. As the wall depth decreased, the constraints and load on the bottom of the wall showed obvious changes, leading to a reduced stress and damage level of the wall. The findings provide reference for the design and safety control of cut-off walls. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

47. A Hypoplastic Model with Isotropic and Oedometric Proportional Paths.

Author

Wang, Kaituo, Li, Linke, and Guo, Xiaogang

Subjects
*COMPUTER simulation, *CALIBRATION
Abstract

To accurately represent the proportional stress–strain behavior observed in granular materials, we extend the hypoplastic model originally proposed by Gudehus and Bauer. This extension incorporates two new tensorial terms. By introducing these terms and their associated coefficients, we establish an implicit relationship for oedometric proportional compression. Our numerical simulations, based on element tests, demonstrate that this extended model effectively describes the isotropic and oedometric proportional stress–strain behavior of granular materials. Furthermore, we outline the process for determining the constitutive parameters and discuss the corresponding calibration methods within this study. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results