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3. Comparative effectiveness of hysterectomy versus myomectomy on one-year health-related quality of life in women with uterine fibroids

Author

Wallace, Kedra, Zhang, Shuaiqi, Thomas, Laine, Stewart, Elizabeth A., Nicholson, Wanda Kay, Wegienka, Ganesa R., Wise, Lauren A., Laughlin-Tommaso, Shannon K., Diamond, Michael P., Marsh, Erica E., Jacoby, Vanessa L., Anchan, Raymond M., Venable, Sateria, Larry, G. Maxwell, Lytle, Barbara, Wang, Tracy, and Myers, Evan R.

Published
2020
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4. The impact of prenatal dog keeping on infant gut microbiota development

Author

Panzer, Ariane R., primary, Sitarik, Alexandra R., additional, Fadrosh, Doug, additional, Havstad, Suzanne L., additional, Jones, Kyra, additional, Davidson, Brent, additional, Finazzo, Salvatore, additional, Wegienka, Ganesa R., additional, Woodcroft, Kimberley, additional, Lukacs, Nicholas W., additional, Levin, Albert M., additional, Ownby, Dennis R., additional, Johnson, Christine C., additional, Lynch, Susan V., additional, and Zoratti, Edward M., additional

Published
2023
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6. Anxiety, Depression, and Quality of Life After Procedural Intervention for Uterine Fibroids

Author

Wallace, Kedra, primary, Stewart, Elizabeth A., additional, Wise, Lauren A., additional, Nicholson, Wanda Kay, additional, Parry, John Preston, additional, Zhang, Shuaiqi, additional, Laughlin-Tommaso, Shannon, additional, Jacoby, Vanessa, additional, Anchan, Raymond M., additional, Diamond, Michael P., additional, Venable, Sateria, additional, Shiflett, Amber, additional, Wegienka, Ganesa R., additional, Maxwell, George Larry, additional, Wojdyla, Daniel, additional, Myers, Evan R., additional, and Marsh, Erica, additional

Published
2022
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7. Correlates of plasma concentrations of per- and poly-fluoroalkyl substances among reproductive-aged Black women

Author

Wise, Lauren A., primary, Wesselink, Amelia K., additional, Schildroth, Samantha, additional, Calafat, Antonia M., additional, Bethea, Traci N., additional, Geller, Ruth J., additional, Coleman, Chad M., additional, Fruh, Victoria, additional, Claus Henn, Birgit, additional, Botelho, Julianne C., additional, Harmon, Quaker E., additional, Thirkill, Maya, additional, Wegienka, Ganesa R., additional, and Baird, Donna D., additional

Published
2022
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15. The Comparing Options for Management: PAtient-centered REsults for Uterine Fibroids (COMPARE-UF) registry: rationale and design

Author

Stewart, Elizabeth A., primary, Lytle, Barbara L., additional, Thomas, Laine, additional, Wegienka, Ganesa R, additional, Jacoby, Vanessa, additional, Diamond, Michael P., additional, Nicholson, Wanda K., additional, Anchan, Raymond M., additional, Venable, Sateria, additional, Wallace, Kedra, additional, Marsh, Erica E., additional, Maxwell, George L., additional, Borah, Bijan J., additional, Catherino, William H., additional, and Myers, Evan R., additional

Published
2018
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17. Breastfeeding Is Associated with Infant Gut Microbial Composition

Author

Jones, Kyra J., primary, Sitarik, Alexandra R., additional, Fujimura, Kei, additional, Johnson, Christine Cole, additional, Havstad, Suzanne, additional, Kim, Haejin, additional, Cassidy-Bushrow, Andrea, additional, Bobbitt, Kevin, additional, Lukacs, Nicholas W., additional, Woodcroft, Kimberley J., additional, Zoratti, Edward M., additional, Levin, Albert M., additional, Wegienka, Ganesa R., additional, Lynch, Susan V., additional, Boushey, Homer A., additional, and Ownby, Dennis R., additional

Published
2015
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18. The Infant Gut Microbiome Mediates the Association Between Breastfeeding and Allergic-like Response to Pets in Children

Author

Sitarik, Alexandra R., primary, Havstad, Suzanne, additional, Levin, Albert M., additional, Fujimura, Kei, additional, Wegienka, Ganesa R., additional, Zoratti, Edward M., additional, Ownby, Dennis R., additional, Kim, Haejin, additional, Boushey, Homer A., additional, Lynch, Susan V., additional, and Johnson, Christine Cole, additional

Published
2015
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19. Maternal and Birth Chracterestics Are Associated with Infant Gut Microbial Composition

Author

Johnson, Christine Cole, primary, Havstad, Suzanne, additional, Zoratti, Edward M., additional, Fujimura, Kei, additional, Sitarik, Alexandra R., additional, Kim, Haejin, additional, Cassidy-Bushrow, Andrea, additional, Bobbitt, Kevin, additional, Lukacs, Nicholas W., additional, Woodcroft, Kimberley J., additional, Boushey, Homer A., additional, Ownby, Dennis R., additional, Wegienka, Ganesa R., additional, Levin, Albert M., additional, and Lynch, Susan V., additional

Published
2015
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20. Influence of Infant Gut Microbiome on Development of Infant Regulatory T Cells

Author

Bobbitt, Kevin, primary, Levin, Albert M., additional, Havstad, Suzanne, additional, Sitarik, Alexandra R., additional, Fujimura, Kei, additional, Woodcroft, Kimberley J., additional, Wegienka, Ganesa R., additional, Zoratti, Edward M., additional, Cassidy-Bushrow, Andrea, additional, Kim, Haejin, additional, Boushey, Homer A., additional, Ownby, Dennis, additional, Johnson, Christine Cole, additional, Lukacs, Nicholas W., additional, and Lynch, Susan V., additional

Published
2015
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21. Association of the Infant Gastrointestinal Microbiome with Nocturnal Symptoms in Children with Asthma

Author

Levin, Albert M., primary, Havstad, Suzanne, additional, Sitarik, Alexandra R., additional, Joseph, Christine L.M., additional, Fujimura, Kei, additional, Wegienka, Ganesa R., additional, Zoratti, Edward M., additional, Kim, Haejin, additional, Johnson, Christine Cole, additional, Boushey, Homer A., additional, Lynch, Susan V., additional, and Ownby, Dennis R., additional

Published
2015
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25. Associations of per- and polyfluoroalkyl substances with uterine leiomyomata incidence and growth: a prospective ultrasound study.

Author

Wise LA, Coleman CM, Schildroth S, Geller RJ, Lovett SM, Claus Henn B, Calafat AM, Botelho JC, Marsh EE, Noel N, Wegienka GR, Bethea TN, Harmon QE, Baird DD, and Wesselink AK

Abstract

Background: Per- and polyfluoroalkyl substances (PFAS) are endocrine-disrupting chemicals used in commercial and consumer products., Objective: We evaluated PFAS exposure in relation to incidence and growth of uterine leiomyomata (UL), hormone-dependent neoplasms that are associated with severe gynecologic morbidity., Methods: We studied 1158 participants in the Study of Environment, Lifestyle, and Fibroids, a Detroit-based prospective cohort study of Black females aged 23-35 years at enrollment (2010-2012). At enrollment and four subsequent visits during 10 years of follow-up, participants attended in-person clinic visits, completed questionnaires, provided non-fasting blood samples, and underwent ultrasound for UL detection. We quantified 7 PFAS in baseline plasma samples using mass spectrometry. We used Cox regression and probit Bayesian kernel machine regression to estimate individual and joint effects of PFAS on UL incidence. We fit linear mixed models to estimate effects of individual PFAS on UL growth. We stratified by parity, an important route of PFAS elimination and determinant of UL., Results: In individual PFAS analyses, we observed inverse associations for perfluorodecanoate (PFDA; ≥0.3 vs. <0.2 ng/ml: hazard ratio [HR] = 0.74; 95% confidence interval [CI]: 0.54-1.00) and perfluoroundecanoate (detected vs. non-detected: HR = 0.78; 95% CI: 0.61-1.01) and a weak positive association for perfluorohexane sulfonate (≥1 vs. <0.6 ng/ml: HR = 1.17; 95% CI: 0.85-1.61), while perfluorooctane sulfonate, perfluorooctanoate, perfluorononanoate (PFNA), and 2-N-methyl-perfluorooctane sulfonamido acetate (MeFOSAA) showed little association with UL incidence. The PFAS mixture was inversely associated with UL incidence, a finding driven by MeFOSAA and PFDA; however, PFNA was positively associated with UL incidence. The inverse association for PFDA and positive association for PFNA were stronger among nulliparous participants. Most PFAS showed slight inverse associations with UL growth., Impact Statement: In this prospective ultrasound study of 1158 Black females aged 23-35 years at enrollment, we conducted a mixtures analysis to account for co-pollutant confounding and interaction. MeFOSAA and PFDA concentrations were inversely associated with UL incidence, while PFNA concentrations were positively associated with UL incidence. Concentrations of most PFAS were associated with decreased UL growth. This study contributes data to the sparse literature on PFAS exposure and UL development., (© 2024. The Author(s), under exclusive licence to Springer Nature America, Inc.)

Published
2024
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26. Introduction of a community health worker diabetes coach improved glycemic control in an urban primary care clinic.

Author

Coleman CM, Bossick AS, Zhou Y, Hopkins-Johnson L, Otto MG, Nair AS, Willens DE, and Wegienka GR

Abstract

The burden of diabetes is higher in urban areas and among racial and ethnic minorities. The purpose of this research was to evaluate the effectiveness of extending a diabetes intervention program (DIP) by engaging a team, including a community health worker (CHW), to provide care for patients to meet glycemic control, specifically in a predominantly urban, minority patient population. The DIP enrolled diabetic patients from an internal medicine clinic. A CHW facilitated the collection of glucose meter readings. The CHW coached patients on glycemic control while the CHW's registered nurse partner titrated the patient's recommended insulin dose. Subsequent HbA1c values for participants were compared to those seen at the same clinic who were not enrolled. The DIP was deployed for nine months. One hundred forty-four patients were enrolled in the DIP and 348 patients constituted the comparator group. Ninety-three DIP participants had pre- and post-intervention HbA1c values and were compared to 348 non-DIP participants. Propensity score weighted adjusted analyses suggest that participants were more likely to reduce their HbA1c values by at least 1.0% and have HbA1c values of less than 8.0% (64 mmol/mol) than non-participants (adjusted odds ratio = aOR = 1.47, 95% CI 1.26-1.71, and aOR = 1.23, 95% CI 1.06-1.43, respectively). CHW coaches as part of a team in a clinical setting improved glycemic control in a predominantly urban, minority patient population., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2020 The Authors.)

Published
2020
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