313 results on '"Wen, Xiaoan"'
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2. Synthesis and in vitro/in vivo anticancer evaluation of pentacyclic triterpenoid derivatives linked with l-phenylalanine or l-proline
3. Identification of indole-based activators of insulin degrading enzyme
4. Organophosphorus-Catalyzed Direct Dehydroxylative Thioetherification of Alcohols with Hypervalent Organosulfur Compounds
5. Synthesis of indole-fused scaffolds via [3+3] cyclization reaction of 2-indolylmethanols with quinone imines
6. Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid
7. PIII/PV‑Catalyzed Beckmann Reaction and Sequential [2,3]-Sigmatropic Rearrangement to Construct 2‑Amidopyridines.
8. Discovery of Novel PD-L1 Small-Molecular Inhibitors with Potent In Vivo Anti-tumor Immune Activity.
9. Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I
10. N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure–activity relationships and X-ray crystallographic studies
11. Developing a binuclear multi-target Bi(III) complex by optimizing 2-acetyl-3-ethylpyrazine thiosemicarbazides
12. N-substituted-3(10H)-acridones as visible-light photosensitizers for organic photoredox catalysis
13. Discovery of pentacyclic triterpene 3β-ester derivatives as a new class of cholesterol ester transfer protein inhibitors
14. Discovery of the First Subnanomolar PPARα/δ Dual Agonist for the Treatment of Cholestatic Liver Diseases
15. Fragment-based discovery of novel pentacyclic triterpenoid derivatives as cholesteryl ester transfer protein inhibitors
16. Design, synthesis, and biological evaluation of (2E)-(2-oxo-1, 2-dihydro-3H-indol-3-ylidene)acetate derivatives as anti-proliferative agents through ROS-induced cell apoptosis
17. (4-Picolylamino)-17β-Estradiol derivative and analogues induce apoptosis with death receptor trail R2/DR5 in MCF-7
18. Synthesis of Polycyclic Fused Oxazolidin-2-Ones by Catalytic Boron(Iii)-Promoted Oxo-Michael Addition Reaction and Evaluation on Their Cytotoxicity
19. ADDP facilitates C–S bond formation from sulfonyl chlorides with alcohols
20. Discovery of Orally Bioavailable N-Benzylpiperidinol Derivatives as Potent and Selective USP7 Inhibitors with In Vivo Antitumor Immunity Activity against Colon Cancer
21. Discovery of highly potent renin inhibitors potentially interacting with the S3′ subsite of renin
22. Organophosphorus-Catalyzed "Dual-Substrate Deoxygenation" Strategy for C–S Bond Formation from Sulfonyl Chlorides and Alcohols/Acids.
23. Approach to N-aryl pyrroles via diphenyl phosphate-catalyzed [1,5]-Hydride shift/isomerization reaction with indoles
24. Quinone methides as [1, 5]-hydride acceptors: approach to N-aryl pyrroles
25. Structure–activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme
26. Synthesis and in vitro/in vivo anticancer evaluation of pentacyclic triterpenoid derivatives linked with -phenylalanine or -proline
27. Synthesis of Functionalized Thiazolidin-2-imine and Oxazolidin-2-one Derivatives from p-Quinamines via [3 + 2] Annulation of Isothiocyanates and CO2
28. Discovery of a Novel Macrocyclic ATP Citrate Lyase Inhibitor
29. Discovery of highly potent DPP-4 inhibitors by hybrid compound design based on linagliptin and alogliptin
30. Proton-exchanged montmorillonite-mediated reactions of methoxybenzyl esters and ethers
31. Synthesis and biological evaluation of all eight stereoisomers of DPP-IV inhibitor saxagliptin
32. Electronic and steric effects on the intramolecular Schmidt reaction of alkyl azides with secondary benzyl alcohols
33. Synthesis of Functionalized Thiazolidin-2-imine and Oxazolidin-2-one Derivatives from p‑Quinamines via [3 + 2] Annulation of Isothiocyanates and CO2.
34. Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPARα/δ Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis
35. Diversity Synthesis of Indole-derivatives via Catalyst Control Cyclization Reaction of 2-Indolylmethanols and Azonaphthalene
36. Synthesis and in Vitro/In Vivo Anticancer Evaluation of Pentacyclic Triterpenoid Derivatives Linked with L-Phenylalanine or L-Proline
37. Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies
38. The STING antagonist H‐151 ameliorates psoriasis via suppression of STING/NF‐κB‐mediated inflammation
39. Chiral Phosphoric Acid Catalyzed Asymmetric Desymmetrization of para-Quinamines with Isocyanates: Access to Functionalized Imidazolidin-2-one Derivatives
40. Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction
41. Cu-Catalyzed Dimerization of Indole Derived Oxime Acetate for Synthesis of Biimidazo[1,2-a]indoles
42. Synthesis and Evaluation of Novel Oleanolic Acid Derivatives as Potential Antidiabetic Agents
43. Synthesis, biological evaluation and SAR studies of ursolic acid 3β-ester derivatives as novel CETP inhibitors
44. Discovery of Ubiquitin-Specific Protease 7 (USP7) Inhibitors with Novel Scaffold Structures by Virtual Screening, Molecular Dynamics Simulation, and Biological Evaluation
45. Discovery of Novel Peroxisome Proliferator-Activated Receptor α (PPARα) Agonists by Virtual Screening and Biological Evaluation
46. A Selectivity Study of FFAR4/FFAR1 Agonists by Molecular Modeling
47. Synergistic antitumor activity of artesunate and HDAC inhibitors through elevating heme synthesis via synergistic upregulation of ALAS1 expression
48. Synthesis and anti-cancer activity of ND-646 and its derivatives as acetyl-CoA carboxylase 1 inhibitors
49. Synthesis and biological evaluation of Complex I inhibitor R419 and its derivatives as anticancer agents in HepG2 cells
50. Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design
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