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1. Conformationally Constrained Substance P Analogues: The Total Synthesis of a Constrained...

Author

Yunsong Tong and Fobian, Yvette M.

Subjects
*ORGANIC synthesis, *LACTAMS, *SUBSTANCE P, *AMIDES, *PHENYLALANINE
Abstract

Reports on the synthesis of a lactam-based peptidomimetic for the Phe7-Phe8 region of substance P. Application of an anodic amide oxidation to selectively functionalize the C5-position of a 3-phenylproline derivative; Coupling of the resulting proline derivative to a Cbz-protected phenylalanine.

Published
2000
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