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New biodegradable paper-based films are a hot research topic in the development of green agriculture. In this study, a black paper-based film coated with cooked tung oil with excellent mechanical properties, a hydrophobic surface, high heat transfer and strong weather resistance was prepared by spraying high-pigment carbon black solution on the surface of base paper. The results showed that the surface-solidified oil film had a rough structure produced via the brush coating process using cooked tung oil. The base film of the black paper had a given hydrophobic structure, and the contact angle reached 98.9°. Cooked tung oil permeates into the inside of the paper base, and after curing, it forms a multi-dimensional network film structure. The maximum tensile stress of the black paper base film is about 123% higher than that of the original paper base film. The coloring of carbon black gives the black paper base film a heat conduction effect, and the average heat transfer rate reaches 15.12 °C/s. Cooked tung oil is combined with the paper-based fiber high-toughness layer to form a stable system. The existence of a cured film improves the basic mechanics and hydrophobicity, and the resistance to ultraviolet radiation and hot air is greatly improved. This study provides a feasible scheme for the application of a black paper base film coated with cooked tung oil. [ABSTRACT FROM AUTHOR]

Cancer remains the most common lethal disease in the world. Although the treatment choices for cancer are still limited, significant progress has been made over the past few years. By improving targeted drug therapy, drug delivery systems promoted the therapeutic effects of anti-cancer medications. Exosome is a kind of natural nanoscale delivery system with natural substance transport properties, good biocompatibility, and high tumor targeting, which shows great potential in drug carriers, thereby providing novel strategies for cancer therapy. In this review, we present the formation, distribution, and characteristics of exosomes. Besides, extraction and isolation techniques are discussed. We focus on the recent progress and application of exosomes in cancer therapy in four aspects: exosome-mediated gene therapy, chemotherapy, photothermal therapy, and combination therapy. The current challenges and future developments of exosome-mediated cancer therapy are also discussed. Finally, the latest advances in the application of exosomes as drug delivery carriers in cancer therapy are summarized, which provide practical value and guidance for the development of cancer therapy. [ABSTRACT FROM AUTHOR]

The increasing incidence of aircraft cargo compartment fires in recent years has caused heavy losses and drawn attention to understanding the combustion process, especially under low pressure. The present paper aims at exploring the conditions of flashover at different pressures. Experiments were conducted in Guanghan (96 kPa) and Kangding (60 kPa), which are located at different altitudes. Five different sizes of pool fires were tested and smoke temperature and heat flux were measured for flashover criteria analysis. Corresponding simulations were performed using a commercial software FDS to examine the pressure effect on the flashover phenomenon and to validate the simulation results. The critical conditions for the onset of flashover in a 1/4 MPS compartment were found to be (1) an average upper layer temperature of about 450 °C at 96 kPa or about 550 °C at 60 kPa, and (2) radiant heat flux at floor level of about 10 to 15 kW/m2 at 96 kPa or 20 to 25 kW/m2 at 60 kPa. By using the average upper layer temperature as a criterion in modeling, a relatively accurate prediction of flashover onset time could be obtained at 96 kPa and a delay of about 25 s was found at 60 kPa. [ABSTRACT FROM AUTHOR]