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6. Effects of epoxy resin on the high‐temperature performance of desulfurized rubber modified asphalt.

Author

Li, Junwei, Su, Haobo, Yang, Dan, Jia, Yanzhen, Jiao, Xiaolei, Zheng, Liansheng, Lu, Wenxue, and Zhao, Yongke

Subjects
EPOXY resins, ASPHALT, RUBBER, RHEOLOGY
Abstract

In order to improve the performance of desulphurized rubber modified asphalt, especially the high‐temperature performance, epoxy resin was selected to modify the modified asphalt with three curing agent and accelerator components. The conventional properties, rheological properties, curing effect, process energy, and modification mechanism of epoxy resin—desulfurized rubber modified asphalt were analyzed. The experimental results show that the addition of epoxy resin to asphalt can all improve the high‐temperature performance of modified asphalt. The promoter component (PC) further improves the high‐temperature performance and reduces the viscosity. Among them, diaminodiphenyl sulfone and methylhexahydrophthalic anhydride in a 1:1 mass combination with epoxy resin modified asphalt not only had better high‐temperature performance, but also had excellent low‐temperature performance and ideal curing process. From the results, it can be seen that 5% epoxy resin with mixed curing agent with 3% PC had the best overall performance. [ABSTRACT FROM AUTHOR]

Published
2024
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7. A Comparison of Whole-Genome Shotgun-Derived Mouse Chromosome 16 and the Human Genome

Author

Mural, Richard J., Adams, Mark D., Myers, Eugene W., Smith, Hamilton O., Wides, Ron, Halpern, Aaron, Li, Peter W., Sutton, Granger G., Nadeau, Joe, Salzberg, Steven L., Holt, Robert A., Kodira, Chinnappa D., Lu, Fu, Chen, Lin, Deng, Zuoming, Evangelista, Carlos C., Gan, Weiniu, Heiman, Thomas J., Li, Jiayin, Li, Zhenya, Merkulov, Gennady V., Milshina, Natalia V., Naik, Ashwinikumar K., Qi, Rong, Shue, Bixiong Chris, Wang, Aihui, Wang, Jian, Wang, Xin, Yan, Xianghe, Ye, Jane, Yooseph, Shibu, Zhao, Qi, Zheng, Liansheng, Zhu, Shiaoping C., Biddick, Kendra, Bolanos, Randall, Delcher, Arthur L., Dew, Ian M., Fasulo, Daniel, Flanigan, Michael J., Huson, Daniel H., Kravitz, Saul A., Miller, Jason R., Mobarry, Clark M., Reinert, Knut, Remington, Karin A., Zhang, Qing, Zheng, Xiangqun H., Nusskern, Deborah R., Lai, Zhongwu, Lei, Yiding, Zhong, Wenyan, Yao, Alison, Guan, Ping, Ji, Rui-Ru, Gu, Zhiping, Wang, Zhen-Yuan, Zhong, Fei, Xiao, Chunlin, Chiang, Chia-Chien, Yandell, Mark, Wortman, Jennifer R., Amanatides, Peter G., Hladun, Suzanne L., Pratts, Eric C., Johnson, Jeffery E., Dodson, Kristina L., Woodford, Kerry J., Evans, Cheryl A., Gropman, Barry, Rusch, Douglas B., Venter, Eli, Wang, Mei, Smith, Thomas J., Houck, Jarrett T., Tompkins, Donald E., Haynes, Charles, Jacob, Debbie, Chin, Soo H., Allen, David R., Dahlke, Carl E., Sanders, Robert, Li, Kelvin, Liu, Xiangjun, Levitsky, Alexander A., Majoros, William H., Chen, Quan, Xia, Ashley C., Lopez, John R., Donnelly, Michael T., Newman, Matthew H., Glodek, Anna, Kraft, Cheryl L., Nodell, Marc, Ali, Feroze, An, Hui-Jin, Baldwin-Pitts, Danita, Beeson, Karen Y., Cai, Shuang, Carnes, Mark, Carver, Amy, Caulk, Parris M., Chen, Yen-Hui, Cheng, Ming-Lai, Coyne, My D., Crowder, Michelle, Danaher, Steven, Davenport, Lionel B., Desilets, Raymond, Dietz, Susanne M., Doup, Lisa, Dullaghan, Patrick, Ferriera, Steven, Fosler, Carl R., Gire, Harold C., Gluecksmann, Andres, Gocayne, Jeannine D., Gray, Jonathan, Hart, Brit, Haynes, Jason, Hoover, Jeffery, Howland, Tim, Ibegwam, Chinyere, Jalali, Mena, Johns, David, Kline, Leslie, Ma, Daniel S., MacCawley, Steven, Magoon, Anand, Mann, Felecia, May, David, McIntosh, Tina C., Mehta, Somil, Moy, Linda, Moy, Mee C., Murphy, Brian J., Murphy, Sean D., Nelson, Keith A., Nuri, Zubeda, Parker, Kimberly A., Prudhomme, Alexandre C., Puri, Vinita N., Qureshi, Hina, Raley, John C., Reardon, Matthew S., Regier, Megan A., Rogers, Yu-Hui C., Romblad, Deanna L., Schutz, Jakob, Scott, John L., Scott, Richard, Sitter, Cynthia D., Smallwood, Michella, Sprague, Arlan C., Stewart, Erin, Strong, Renee V., Suh, Ellen, Sylvester, Karena, Thomas, Reginald, Tint, Tsonis, Christopher, Wang, Gary, Wang, George, Williams, Monica S., Williams, Sherita M., Windsor, Sandra M., Wolfe, Keriellen, Wu, Mitchell M., Zaveri, Jayshree, Chaturvedi, Kabir, Gabrielian, Andrei E., Ke, Zhaoxi, Sun, Jingtao, Subramanian, Gangadharan, and Venter, J. Craig

Published
2002

8. The Sequence of the Human Genome

Author

Venter, J. Craig, Adams, Mark D., Myers, Eugene W., Li, Peter W., Mural, Richard J., Sutton, Granger G., Smith, Hamilton O., Yandell, Mark, Evans, Cheryl A., Holt, Robert A., Gocayne, Jeannine D., Amanatides, Peter, Ballew, Richard M., Huson, Daniel H., Wortman, Jennifer Russo, Zhang, Qing, Kodira, Chinnappa D., Zheng, Xiangqun H., Chen, Lin, Skupski, Marian, Subramanian, Gangadharan, Thomas, Paul D., Zhang, Jinghui, Nelson, Catherine, Broder, Samuel, Clark, Andrew G., Nadeau, Joe, McKusick, Victor A., Zinder, Norton, Levine, Arnold J., Roberts, Richard J., Simon, Mel, Slayman, Carolyn, Hunkapiller, Michael, Bolanos, Randall, Delcher, Arthur, Dew, Ian, Fasulo, Daniel, Flanigan, Michael, Florea, Liliana, Halpern, Aaron, Hannenhalli, Sridhar, Kravitz, Saul, Levy, Samuel, Mobarry, Clark, Reinert, Knut, Remington, Karin, Abu-Threideh, Jane, Beasley, Ellen, Biddick, Kendra, Bonazzi, Vivien, Brandon, Rhonda, Cargill, Michele, Chandramouliswaran, Ishwar, Charlab, Rosane, Chaturvedi, Kabir, Deng, Zuoming, Di Francesco, Valentina, Dunn, Patrick, Eilbeck, Karen, Evangelista, Carlos, Gabrielian, Andrei E., Gan, Weiniu, Ge, Wangmao, Gong, Fangcheng, Gu, Zhiping, Guan, Ping, Heiman, Thomas J., Higgins, Maureen E., Ji, Rui-Ru, Ke, Zhaoxi, Ketchum, Karen A., Lai, Zhongwu, Lei, Yiding, Li, Zhenya, Li, Jiayin, Liang, Yong, Lin, Xiaoying, Lu, Fu, Merkulov, Gennady V., Milshina, Natalia, Moore, Helen M., Naik, Ashwinikumar K, Narayan, Vaibhav A., Neelam, Beena, Nusskern, Deborah, Rusch, Douglas B., Salzberg, Steven, Shao, Wei, Shue, Bixiong, Sun, Jingtao, Wang, Zhen Yuan, Wang, Aihui, Wang, Xin, Wang, Jian, Wei, Ming-Hui, Wides, Ron, Xiao, Chunlin, Yan, Chunhua, Yao, Alison, Ye, Jane, Zhan, Ming, Zhang, Weiqing, Zhang, Hongyu, Zhao, Qi, Zheng, Liansheng, Zhong, Fei, Zhong, Wenyan, Zhu, Shiaoping C., Zhao, Shaying, Gilbert, Dennis, Baumhueter, Suzanna, Spier, Gene, Carter, Christine, Cravchik, Anibal, Woodage, Trevor, Ali, Feroze, An, Huijin, Awe, Aderonke, Baldwin, Danita, Baden, Holly, Barnstead, Mary, Barrow, Ian, Beeson, Karen, Busam, Dana, Carver, Amy, Cheng, Ming Lai, Curry, Liz, Danaher, Steve, Davenport, Lionel, Desilets, Raymond, Dietz, Susanne, Dodson, Kristina, Doup, Lisa, Ferriera, Steven, Garg, Neha, Gluecksmann, Andres, Hart, Brit, Haynes, Jason, Haynes, Charles, Heiner, Cheryl, Hladun, Suzanne, Hostin, Damon, Houck, Jarrett, Howland, Timothy, Ibegwam, Chinyere, Johnson, Jeffery, Kalush, Francis, Kline, Lesley, Koduru, Shashi, Love, Amy, Mann, Felecia, May, David, McCawley, Steven, Mclntosh, Tina, McMullen, Ivy, Moy, Mee, Moy, Linda, Murphy, Brian, Nelson, Keith, Pfannkoch, Cynthia, Pratts, Eric, Puri, Vinita, Qureshi, Hina, Reardon, Matthew, Rodriguez, Robert, Rogers, Yu-Hui, Romblad, Deanna, Ruhfel, Bob, Scott, Richard, Sitter, Cynthia, Smallwood, Michelle, Stewart, Erin, Strong, Renee, Suh, Ellen, Thomas, Reginald, Tint, Tse, Sukyee, Vech, Claire, Wang, Gary, Wetter, Jeremy, Williams, Sherita, Williams, Monica, Windsor, Sandra, Winn-Deen, Emily, Wolfe, Keriellen, Zaveri, Jayshree, Zaveri, Karena, Abril, Josep F., Guigó, Roderic, Campbell, Michael J., Sjolander, Kimmen V., Karlak, Brian, Kejariwal, Anish, Mi, Huaiyu, Lazareva, Betty, Hatton, Thomas, Narechania, Apurva, Diemer, Karen, Muruganujan, Anushya, Guo, Nan, Sato, Shinji, Bafna, Vineet, Istrail, Sorin, Lippert, Ross, Schwartz, Russell, Walenz, Brian, Yooseph, Shibu, Allen, David, Basu, Anand, Baxendale, James, Blick, Louis, Caminha, Marcelo, Carnes-Stine, John, Caulk, Parris, Chiang, Yen-Hui, Coyne, My, Dahlke, Carl, Mays, Anne Deslattes, Dombroski, Maria, Donnelly, Michael, Ely, Dale, Esparham, Shiva, Fosler, Carl, Gire, Harold, Glanowski, Stephen, Glasser, Kenneth, Glodek, Anna, Gorokhov, Mark, Graham, Ken, Gropman, Barry, Harris, Michael, Heil, Jeremy, Henderson, Scott, Hoover, Jeffrey, Jennings, Donald, Jordan, Catherine, Jordan, James, Kasha, John, Kagan, Leonid, Kraft, Cheryl, Levitsky, Alexander, Lewis, Mark, Liu, Xiangjun, Lopez, John, Ma, Daniel, Majoros, William, McDaniel, Joe, Murphy, Sean, Newman, Matthew, Nguyen, Trung, Nguyen, Ngoc, Nodell, Marc, Pan, Sue, Peck, Jim, Peterson, Marshall, Rowe, William, Sanders, Robert, Scott, John, Simpson, Michael, Smith, Thomas, Sprague, Arlan, Stockwell, Timothy, Turner, Russell, Venter, Eli, Wang, Mei, Wen, Meiyuan, Wu, David, Wu, Mitchell, Xia, Ashley, Zandieh, Ali, and Zhu, Xiaohong

Published
2001

9. Comparison of different blood vessels as markers in laparoscopic radical resection of right colon cancer.

Author

ZHANG Ranhao, QIAO Wenjuan, SHI Mengwei, MU Dongdong, and ZHENG Liansheng

Abstract

Objective To compare the clinical efficacy and short-term prognosis of laparoscopic radical resection of right colon cancer guided by superior mesenteric artery and superior mesenteric vein. Methods 80 patients with right colon cancer of cT2-4 and/or N0-2M0 admitted from January 2020 to October 2022 were selected as the research objects, and they were randomly divided into observation group and control group, with 40 patients in each group. The observation group was treated with SMA-oriented laparoscopic radical resection of right colon cancer, while the control group was treated with SMV-oriented laparoscopic radical resection of right colon cancer. The curative effect and prognosis of the two groups were compared. Results There was no significant difference between the two groups in general condition, operation time, gastric tube placement time, recovery time of farting, postoperative fasting time, postoperative drainage time, postoperative nutritional index, total incidence of complications and postoperative hospitalization time(P > 0.05). The lymph nodes in the observation group were significantly more than those in the control group, and the difference was statistically significant(P < 0.05). In the observation group, the lymph nodes in the anterior and left side of superior mesenteric artery were examined (No. D3), and 273 lymph nodes were detected, and Seven patients (17.5%) were diagnosed with D3 metastasis, and 13 lymph nodes were positive (5.2%). Conclusion Laparoscopic radical resection of right colon cancer guided by superior mesenteric artery, without increasing the incidence of complications and high safety, can more thoroughly clean lymph nodes and reduce tumor recurrence, which is expected to significantly improve the prognosis of patients. [ABSTRACT FROM AUTHOR]

Published
2024
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10. The Genome Sequence of Drosophila melanogaster

Author

Adams, Mark D., Celniker, Susan E., Holt, Robert A., Evans, Cheryl A., Gocayne, Jeannine D., Amanatides, Peter G., Scherer, Steven E., Li, Peter W., Hoskins, Roger A., Galle, Richard F., George, Reed A., Lewis, Suzanna E., Richards, Stephen, Ashburner, Michael, Henderson, Scott N., Sutton, Granger G., Wortman, Jennifer R., Yandell, Mark D., Zhang, Qing, Chen, Lin X., Brandon, Rhonda C., Rogers, Yu-Hui C., Blazej, Robert G., Champe, Mark, Pfeiffer, Barret D., Wan, Kenneth H., Doyle, Clare, Baxter, Evan G., Helt, Gregg, Nelson, Catherine R., Abril, Josep F., Agbayani, Anna, An, Hui-Jin, Andrews-Pfannkoch, Cynthia, Baldwin, Danita, Ballew, Richard M., Basu, Anand, Baxendale, James, Bayraktaroglu, Leyla, Beasley, Ellen M., Beeson, Karen Y., Benos, P. V., Berman, Benjamin P., Bhandari, Deepali, Bolshakov, Slava, Borkova, Dana, Botchan, Michael R., Bouck, John, Brokstein, Peter, Brottier, Phillipe, Burtis, Kenneth C., Busam, Dana A., Butler, Heather, Cadieu, Edouard, Chandra, Ishwar, Cherry, J. Michael, Cawley, Simon, Dahlke, Carl, Davenport, Lionel B., Davies, Peter, de Pablos, Beatriz, Delcher, Arthur, Deng, Zuoming, Mays, Anne Deslattes, Dew, Ian, Dietz, Suzanne M., Dodson, Kristina, Doup, Lisa E., Downes, Michael, Dugan-Rocha, Shannon, Dunkov, Boris C., Dunn, Patrick, Durbin, Kenneth J., Evangelista, Carlos C., Ferraz, Concepcion, Ferriera, Steven, Fleischmann, Wolfgang, Fosler, Carl, Gabrielian, Andrei E., Garg, Neha S., Gelbart, William M., Glasser, Ken, Glodek, Anna, Gong, Fangcheng, Gorrell, J. Harley, Gu, Zhiping, Guan, Ping, Harris, Michael, Harris, Nomi L., Harvey, Damon, Heiman, Thomas J., Hernandez, Judith R., Houck, Jarrett, Hostin, Damon, Houston, Kathryn A., Howland, Timothy J., Wei, Ming-Hui, Ibegwam, Chinyere, Jalali, Mena, Kalush, Francis, Karpen, Gary H., Ke, Zhaoxi, Kennison, James A., Ketchum, Karen A., Kimmel, Bruce E., Kodira, Chinnappa D., Kraft, Cheryl, Kravitz, Saul, Kulp, David, Lai, Zhongwu, Lasko, Paul, Lei, Yiding, Levitsky, Alexander A., Li, Jiayin, Li, Zhenya, Liang, Yong, Lin, Xiaoying, Liu, Xiangjun, Mattei, Bettina, McIntosh, Tina C., McLeod, Michael P., McPherson, Duncan, Merkulov, Gennady, Milshina, Natalia V., Mobarry, Clark, Morris, Joe, Moshrefi, Ali, Mount, Stephen M., Moy, Mee, Murphy, Brian, Murphy, Lee, Muzny, Donna M., Nelson, David L., Nelson, David R., Nelson, Keith A., Nixon, Katherine, Nusskern, Deborah R., Pacleb, Joanne M., Palazzolo, Michael, Pittman, Gjange S., Pan, Sue, Pollard, John, Puri, Vinita, Reese, Martin G., Reinert, Knut, Remington, Karin, Scheeler, Frederick, Shen, Hua, Shue, Bixiang Christopher, Sidén-Kiamos, Inga, Simpson, Michael, Skupski, Marian P., Smith, Tom, Spier, Eugene, Spradling, Allan C., Stapleton, Mark, Strong, Renee, Sun, Eric, Svirskas, Robert, Tector, Cyndee, Turner, Russell, Venter, Eli, Wang, Aihui H., Wang, Xin, Wang, Zhen-Yuan, Wassarman, David A., Weinstock, George M., Weissenbach, Jean, Williams, Sherita M., Woodage, Trevor, Worley, Kim C., Wu, David, Yang, Song, Yao, Q. Alison, Ye, Jane, Yeh, Ru-Fang, Zaveri, Jayshree S., Zhan, Ming, Zhang, Guangren, Zhao, Qi, Zheng, Liansheng, Zheng, Xiangqun H., Zhong, Fei N., Zhong, Wenyan, Zhou, Xiaojun, Zhu, Shiaoping, Zhu, Xiaohong, Smith, Hamilton O., Gibbs, Richard A., Myers, Eugene W., Rubin, Gerald M., and Venter, J. Craig

Published
2000

15. High‐Speed Rail Service and the Issuance of Municipal Corporate Bonds.

Author

Zheng, Liansheng, Li, Juncheng, and Zhao, Zhihua

Abstract

This study uses the difference‐in‐differences method to test the impact of a high‐speed rail (HSR) service on the issuance of municipal corporate bonds (MCB) based on panel data for prefecture‐level cities in China from 2003 to 2016. The study has three findings. First, HSR increased the scale of the issuance of MCB significantly. After conducting a series of robustness tests, the above conclusion remained robust. Second, HSR affected the issuance of MCB by increasing the city's financing demands and improving the c ity's financing capacity. Third, the effect of HSR on the issuance of MCB varied from city to city. Specifically, the promotion of the opening of HSR to the issuance of MCB was concentrated in remote and fast growing cities. High‐speed rail can also effectively reduce the cost and shrink credit spreads of the MCB. This paper shows that it is necessary to further optimize the layout of HSR, release and exploit the financial resource reallocation effect of HSR, and provide financial support to the high‐quality development of cities. [ABSTRACT FROM AUTHOR]

Published
2022
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16. Authority and Autonomy without Independence: The Gradual Institutional Change of the Chinese Central Bank.

Author

Zheng, Liansheng and Wang, Hongying

Subjects
*TWENTY-first century, *CENTRAL bank independence, *CENTRAL banking industry, *FOREIGN exchange, CHINESE economic policy, ECONOMIC conditions in China, 2000-
Abstract

The People's Bank of China (PBC)has played an important role in China's sustained economic growth. Despite its limited formal independence, PBC has developed considerable de facto authority and autonomy, referered to here as central bank discretion (CBD). This article offers a detailed historical account of how PBChas gained growing CBD in areas such as monetary policy, financial stability, foreign exchange and financial regulation. It also analyzes the main underlying forces that have contributed to PBC's authority and autonomy.This study of CBD in China seeks to enrich the existing literature on the political economy of central banking, which has so far focused heavily on the concept of central bank independence (CBI). [ABSTRACT FROM AUTHOR]

Published
2021
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18. Potential of C1QTNF1-AS1 regulation in human hepatocellular carcinoma.

Author

Han, Weijie, Yu, Guofeng, Meng, Xianmei, Hong, Hong, Zheng, Liansheng, Wu, Xiaobo, Zhang, Dongsheng, Yan, Boshi, Ma, Yongqiang, Li, Xiaolong, and Wang, Qiuhong

Abstract

The aim of our study is to explore the regulation of C1QTNF1-AS1 on its target miR-221-3p/SOCS3 in human hepatocellular carcinoma (HCC). To explore the underlying molecular regulation of non-coding RNA for HCC, differentially expressed patterns of lncRNAs and genes were examined by RNA-seq. GO and KEGG pathway analysis were done based on the function of mRNAs that mediated by differentially expressed lncRNAs. RT-qPCR and western blot were conducted to detect the mRNA and protein level expression of C1QTNF1-AS1, miR-221-3p, SOCS3 and key proteins in JAK/STAT signaling pathway in HCC tissues and cells. The target miRNA of differentially expressed C1QTNF1-AS1 and SOCS3 was miR-221-3p predicted by bioinformatics analysis. C1QTNF1-AS1 and SOCS3 was downregulated and miR-221-3p was upregulated in HCC tissues and cells. In HepG2 and Huh-7 cells, the overexpression of C1QTNF1-AS1 or SOCS3, and silencing of miR-221-3p inhibited proliferation, migration, invasion and JAK/STAT signaling pathway, while promoted cell apoptosis. The results of dual-luciferase assay indicated that C1QTNF1-AS1 regulated miR-221-3p and miR-221-3p targeted SOCS3 by directly binding. And the growth of HCC in vivo was impeded when C1QTNF1-AS1 was upregulated. Overexpression of C1QTNF1-AS1 could downregulate miR-221-3p thereby inhibited the proliferation, migration and invasion of HCC cells. [ABSTRACT FROM AUTHOR]

Published
2019
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19. Is concomitant splenectomy necessary in radical gastric cancer surgery? A systematic review and meta‐analysis.

Author

Wang, Qiuhong, Dang, Tong, Meng, Xianmei, Li, Kai, Ren, Wei, Ma, Xiujuan, Huang, Ying, Wu, Xiaobo, Han, Weijie, Zhang, Dongsheng, Li, Xiaolong, Wang, Da, and Zheng, Liansheng

Subjects
SPLENECTOMY, STOMACH cancer, META-analysis, ONCOLOGIC surgery, FIXED effects model, RANDOM effects model
Abstract

Purpose: This study is a systematic review and meta‐analysis compare the short‐ and long‐term outcomes of splenectomy (SP) versus splenic preservation (NSP) in radical gastric cancer surgery. Methods: A comprehensive search of PubMed, Embase, Cochrane Library and Web of Knowledge was performed. Evaluation of short‐ and long‐term outcomes was collected and analyzed by a fixed or random effects model, according to the heterogeneity using RevMan 5.2 software. Results: A total of 5431 gastric cancer patients who underwent radical surgery (1706 with SP and 3725 with NSP) were reviewed in 11 studies included in this study. Compared with NSP, SP was significantly associated with higher rate of overall postoperative complication and increased incidence of pulmonary complications, abdominal abscess and pancreas complications. No statistical difference was observed regarding mortality, wound infection, anastomotic leakage and postoperative 5‐year overall survival. Conclusion: There was no difference in long‐term oncological outcome but remarkably poorer short‐term outcomes in SP group than NSP group. Therefore, SP seems unnecessary in radical gastric cancer surgery. However, well‐designed, multicenter, prospective, randomized controlled trials are warranted for further validation. [ABSTRACT FROM AUTHOR]

Published
2019
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20. Is Early Oral Feeding after Gastric Cancer Surgery Feasible? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Author

Liu, Xiaoping, Wang, Da, Zheng, Liansheng, Mou, Tingyu, Liu, Hao, and Li, Guoxin

Subjects
STOMACH cancer treatment, GASTRECTOMY, SYSTEMATIC reviews, META-analysis, RANDOMIZED controlled trials, MEDICAL literature, FEASIBILITY studies
Abstract

Aim: To assess the feasibility and safety of early oral feeding (EOF) after gastrectomy for gastric cancer through a systematic review and meta-analysis based on randomized controlled trials. Methods: A literature search in PubMed, Embase, Web of Science and Cochrane library databases was performed for eligible studies published between January 1995 and March 2014. Systematic review was carried out to identify randomized controlled trials comparing EOF and traditional postoperative oral feeding after gastric cancer surgery. Meta-analyses were performed by either a fixed effects model or a random effects model according to the heterogeneity using RevMan 5.2 software. Results: Six studies remained for final analysis. Included studies were published between 2005 and 2013 reporting on a total of 454 patients. No significant differences were observed for postoperative complication (RR = 0.95; 95%CI, 0.70 to 1.29; P = 0.75), the tolerability of oral feeding (RR = 0.98; 95%CI, 0.91 to 1.06; P = 0.61), readmission rate (RR = 1; 95%CI, 0.30 to 3.31; P = 1.00) and incidence of anastomotic leakage (RR = 0.31; 95%CI, 0.01 to 7.30; P = 0.47) between two groups. EOF after gastrectomy for gastric cancer was associated with significant shorter duration of the hospital stay (WMD = −2.36; 95%CI, −3.37 to −1.34; P<0.0001) and time to first flatus (WMD = −19.94; 95%CI, −32.03 to −7.84; P = 0.001). There were no significant differences in postoperative complication, tolerability of oral feeding, readmission rates, duration of hospital stay and time to first flatus among subgroups stratified by the time to start EOF or by partial and total gastrectomy or by laparoscopic and open surgery. Conclusions: The result of this meta-analysis showed that EOF after gastric cancer surgery seems feasible and safe, even started at the day of surgery irrespective of the extent of the gastric resection and the type of surgery. However, more prospective, well-designed multicenter RCTs with more clinical outcomes are needed for further validation. [ABSTRACT FROM AUTHOR]

Published
2014
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