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This paper focuses on an analysis of selected control methods in solar heating systems. Proportional, ON-OFF, and new proposed IPC control methods were tested. Experimental tests were conducted under natural conditions using the author’s method of clustering measurement days. In the form of thermal energy gains in the storage tanks, the results for all tested control methods are presented. The ON-OFF control method is suitable for low variability of solar radiation conditions but is ineffective under dynamic solar radiation conditions. The proportional controllers collect thermal energy under high variability solar radiation effectively, but they tend to cause thermal drifts from the system under high heat load. The proposed IPC control method prevents the waste of heat energy and makes more efficient use of the high and dynamic solar radiation. In conclusion, energy gains depend more on the level of solar radiation and less on its variability. However, the variability of solar radiation makes control in solar systems more challenging, and it is one of the factors that should determine the control strategy. The novelty of this work is based on an extension of the control algorithm by adding the temperature at the entry and exit of the solar coil. This makes it possible to eliminate thermal drift and observe the intensity of heat transfer to the water in the tank.

Background: The ITPR1 gene encodes the inositol 1,4,5‐trisphosphate (IP3) receptor type 1 (IP3R1), a critical player in cerebellar intracellular calcium signaling. Pathogenic missense variants in ITPR1 cause congenital spinocerebellar ataxia type 29 (SCA29), Gillespie syndrome (GLSP), and severe pontine/cerebellar hypoplasia. The pathophysiological basis of the different phenotypes is poorly understood. Objectives: We aimed to identify novel SCA29 and GLSP cases to define core phenotypes, describe the spectrum of missense variation across ITPR1, standardize the ITPR1 variant nomenclature, and investigate disease progression in relation to cerebellar atrophy. Methods: Cases were identified using next‐generation sequencing through the Deciphering Developmental Disorders study, the 100,000 Genomes project, and clinical collaborations. ITPR1 alternative splicing in the human cerebellum was investigated by quantitative polymerase chain reaction. Results: We report the largest, multinational case series of 46 patients with 28 unique ITPR1 missense variants. Variants clustered in functional domains of the protein, especially in the N‐terminal IP3‐binding domain, the carbonic anhydrase 8 (CA8)‐binding region, and the C‐terminal transmembrane channel domain. Variants outside these domains were of questionable clinical significance. Standardized transcript annotation, based on our ITPR1 transcript expression data, greatly facilitated analysis. Genotype–phenotype associations were highly variable. Importantly, while cerebellar atrophy was common, cerebellar volume loss did not correlate with symptom progression. Conclusions: This dataset represents the largest cohort of patients with ITPR1 missense variants, expanding the clinical spectrum of SCA29 and GLSP. Standardized transcript annotation is essential for future reporting. Our findings will aid in diagnostic interpretation in the clinic and guide selection of variants for preclinical studies. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. [ABSTRACT FROM AUTHOR]

Work was carried out to diagnose irregularities in the operation of a vacuum-tube solar collector. Experimental investigations of the collector were carried out at the solar collector field test stand in the Laboratory of Solar Collectors at the Koszalin University of Technology. The scope of the work included the following: research on thermal efficiency characteristics, research on the temperature distribution on the solar collector manifold, and research on the geometric structure of the heat pipe and filling with the working medium. Based on the diagnostic tests carried out, the occurrence of incorrect sedimentation in the condenser on the neck of the heat pipe (44%) and an incorrect amount of working medium (66%) were found. The results show that the functioning of the heat pipe significantly depends on its geometric structure and the amount of working medium. Any irregularity at the production stage contributes to a reduction in the thermal efficiency of the solar collector. The results of the experimental research presented in this paper can be used in the diagnostic analyses of solar systems as well as in the organisation of the manufacturing processes of these systems.

This article presents the results of numerical and experimental studies on the impacts of the selected geometrical features of liquid solar collectors on their thermal efficiency. The experiments were carried out while meeting the requirements of the ISO 9806:2017 standard. Selected changes in the geometrical features were analysed by using fully functional prototypes of modified solar collectors. The correlations between the design and performance properties of the solar collectors were determined in accordance with the changes in the shape of the thermal efficiency η(T*m) curve.

The paper presents ways to use advanced infrared imaging techniques to study and analyze the thermal losses of a flat plate solar collector. The techniques allowed us to precisely locate and measure areas where unwanted thermal losses occurred on the surface of the collectors studied. The study showed that these losses have a key impact on the energy efficiency of these devices. It was found that using the proposed methodology allows not only the detection of defects in existing structures but also the optimization of the design process of new technical solutions. The temperature of the working medium has a significant effect on heat losses on all analyzed surfaces. However, the influence of the medium flow varies depending on the specific surface. The conclusions of the research suggest that infrared imaging is a valuable tool in developing solar thermal systems, contributing to the reliability and efficiency of these systems. The technique is an important step toward sustainable and economical use of solar energy. Increasing the efficiency of the equipment used to carry out the photothermal conversion process will allow more efficient use of available renewable energy sources. It will have a positive impact on environmental protection. [ABSTRACT FROM AUTHOR]

This paper reports the first published prevalence of Multiple endocrine neoplasia type 2B (MEN 2B). Estimates of the epidemiology of MEN 2B were based on a single population with one centralized genetic clinic. MEN 2B remains a relatively rare condition and can be easily missed if the diagnosis has not been considered. [ABSTRACT FROM AUTHOR]

This paper focuses on an analysis of selected control methods in solar heating systems. Proportional, ON-OFF, and new proposed IPC control methods were tested. Experimental tests were conducted under natural conditions using the author's method of clustering measurement days. In the form of thermal energy gains in the storage tanks, the results for all tested control methods are presented. The ON-OFF control method is suitable for low variability of solar radiation conditions but is ineffective under dynamic solar radiation conditions. The proportional controllers collect thermal energy under high variability solar radiation effectively, but they tend to cause thermal drifts from the system under high heat load. The proposed IPC control method prevents the waste of heat energy and makes more efficient use of the high and dynamic solar radiation. In conclusion, energy gains depend more on the level of solar radiation and less on its variability. However, the variability of solar radiation makes control in solar systems more challenging, and it is one of the factors that should determine the control strategy. The novelty of this work is based on an extension of the control algorithm by adding the temperature at the entry and exit of the solar coil. This makes it possible to eliminate thermal drift and observe the intensity of heat transfer to the water in the tank. [ABSTRACT FROM AUTHOR]

Work was carried out to diagnose irregularities in the operation of a vacuum-tube solar collector. Experimental investigations of the collector were carried out at the solar collector field test stand in the Laboratory of Solar Collectors at the Koszalin University of Technology. The scope of the work included the following: research on thermal efficiency characteristics, research on the temperature distribution on the solar collector manifold, and research on the geometric structure of the heat pipe and filling with the working medium. Based on the diagnostic tests carried out, the occurrence of incorrect sedimentation in the condenser on the neck of the heat pipe (44%) and an incorrect amount of working medium (66%) were found. The results show that the functioning of the heat pipe significantly depends on its geometric structure and the amount of working medium. Any irregularity at the production stage contributes to a reduction in the thermal efficiency of the solar collector. The results of the experimental research presented in this paper can be used in the diagnostic analyses of solar systems as well as in the organisation of the manufacturing processes of these systems. [ABSTRACT FROM AUTHOR]

This article presents the results of numerical and experimental studies on the impacts of the selected geometrical features of liquid solar collectors on their thermal efficiency. The experiments were carried out while meeting the requirements of the ISO 9806:2017 standard. Selected changes in the geometrical features were analysed by using fully functional prototypes of modified solar collectors. The correlations between the design and performance properties of the solar collectors were determined in accordance with the changes in the shape of the thermal efficiency η (T * m) curve. [ABSTRACT FROM AUTHOR]