1. Ultra-high resolution optical CT dosimetry for the visualisation of synchrotron microbeam therapy doses
- Author
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Thierry Brochard, Ahmad Taufek Abdul Rahman, John Adamovics, Elke Bräuer-Krisch, Simon J. Doran, Inst Canc Res, CRUK & EPSRC Canc Imaging Ctr, Sutton, Surrey, England, Univ Surrey, Dept Phys, Surrey GU2 7RB, England, Univ Teknol MARA Malaysia, Kuala Lumpur 72000, Malaysia, European Synchrotron Radiation Facility (ESRF), and Rider University
- Subjects
[PHYS]Physics [physics] ,History ,Materials science ,business.industry ,Microbeam ,Ultra high resolution ,Synchrotron ,3. Good health ,030218 nuclear medicine & medical imaging ,Computer Science Applications ,Education ,law.invention ,Visualization ,03 medical and health sciences ,0302 clinical medicine ,Optics ,Microbeam radiation therapy ,law ,030220 oncology & carcinogenesis ,Optical ct ,Dosimetry ,Nuclear medicine ,business ,Image resolution - Abstract
International audience; Optical CT is a method that can potentially provide both accurate dosimetry at high spatial resolution and 3-D visualisation over a large field-of-view in a single dataset. The major factors limiting spatial resolution in previous studies are analysed here and it is shown that improvements in equipment specification can overcome many of these. The need for ultra-high spatial resolution in the verification of microbeam radiation therapy verification is demonstrated and example images of a PRESAGE (R) sample are presented
- Published
- 2012
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