1. Genomic characterization of Listeria spp. isolated from tonsils, udder and feces of domestic dairy ruminants in Spain
- Author
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Carla Palacios-Gorba, Alexandra Moura, Yuval Markovich, Nathalie Tessaud-Rita, Ángel Gómez-Martín, Hélène Bracq-Dieye, Jesús Gomis, Guillaume Vales, María Pastor-Martín, Pierre Thouvenot, Carles Escrig, Alexandre Leclercq, Marc Lecuit, Juan J. Quereda, Universidad Cardenal Herrera-CEU (CEU-UCH), Biologie des Infections - Biology of Infection, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Centre National de Référence Listeria - National Reference Center Listeria (CNR), Centre collaborateur de l'OMS Listeria / WHO Collaborating Centre Listeria (CC-OMS / WHO-CC), Institut Pasteur [Paris] (IP)-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)-Université Paris Cité (UPCité), Generalitat Valenciana, CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), and This work was supported by Generalitat Valenciana (Project reference AICO/2021/278) (JJQ), the Spanish Ministry of Science and Innovation (Project references PID2019-110764RA-I00/AEI/10.13039/501100011033 (JJQ) and PID2020-119462RA-I00/AEI/10.13039/501100011033 (AGM)) and Universidad CEU Cardenal Herrera Programa INDI 20/40 (JJQ), Institut Pasteur, Inserm, and Santé Publique France (ML). J.J. Quereda is supported by a 'Ramón y Cajal' contract of the Spanish Ministry of Science, Innovation, and Universities (RYC-2018-024985-I). C. Palacios-Gorba and Yuval Markovich are supported by a Predoctoral contract from the Universidad Cardenal Herrera-CEU.
- Subjects
[SDV]Life Sciences [q-bio] ,Immunology ,ruminant ,Microbiology ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,Infectious Diseases ,[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology ,udder ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,tonsil ,dairy ,Listeria spp ,WGS ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
International audience; Two species of Listeria are pathogenic, Listeria monocytogenes and Listeria ivanovii. Although studies have shown that dairy ruminants shed Listeria spp. in feces, there is little information about ruminants that do not shed Listeria spp. in their feces but asymptomatically carry them in organs. We evidence that ruminants can asymptomatically carry L. ivanovii in udders and L. monocytogenes and L. ivanovii in tonsils without fecal shedding. Whole-genome sequence of L. monocytogenes and L. ivanovii contained known core genes involved in virulence and antibiotic resistance. This work highlights tonsils and udders as a Listeria intra-host site of colonization.
- Published
- 2022
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