1. Les professionnels de santé face à la pandémie de la maladie à coronavirus (COVID-19) : quels risques pour leur santé mentale ?
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Nefize Yalin, Frank Bellivier, Alessandro Colasanti, Bruno Étain, Tim Mantingh, Paul R. A. Stokes, Jean-Pierre Kahn, Chantal Henry, Marion Leboyer, Rashmi Patel, Allan H. Young, King‘s College London, Bethlem Royal Hospital [London], Brighton and Sussex Medical School (BSMS), Hôpitaux Universitaire Saint-Louis, Lariboisière, Fernand-Widal, Optimisation thérapeutique en Neuropsychopharmacologie (OPTeN (UMR_S_1144 / U1144)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Fondation FondaMental [Créteil], IMRB - 'Neuropsychiatrie translationnelle' [Créteil] (U955 Inserm - UPEC), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Hôpital Henri Mondor, Perception et Mémoire / Perception and Memory, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Centre Psychothérapique de Nancy [Laxou] (CPN), This paper represents independent research supported by the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Authors from France acknowledge the support provided by INSERM (Research Protocol C0829), Assistance Publique des Hôpitaux de Paris (Research Protocol GAN12)., Etain, Bruno, and Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)
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MESH: United Kingdom ,Identification ,MESH: Protective Devices ,[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health ,0302 clinical medicine ,MESH: Risk Factors ,MESH: Bipolar Disorder ,London ,Medicine ,MESH: Tobacco ,Psychotic illness ,MESH: Workload ,education.field_of_study ,MESH: Sleep Wake Disorders ,Mania ,Psychiatry and Mental health ,Clinical Psychology ,Characteristics ,MESH: Stress Disorders, Post-Traumatic ,MESH: Young Adult ,Cohort ,cardiovascular system ,behavior and behavior mechanisms ,France ,medicine.symptom ,MESH: Uncertainty ,MESH: Occupational Diseases ,medicine.medical_specialty ,MESH: Pandemics ,Clinical variables ,MESH: Sleep ,Bipolar disorder ,Population ,MESH: Social Support ,MESH: Mania ,Unipolar mania ,behavioral disciplines and activities ,03 medical and health sciences ,MESH: Infectious Disease Transmission, Patient-to-Professional ,MESH: Severe Acute Respiratory Syndrome ,mental disorders ,Humans ,MESH: SARS-CoV-2 ,education ,Psychiatry ,MESH: Work Schedule Tolerance ,MESH: Helplessness, Learned ,MESH: Humans ,business.industry ,MESH: Influenza Pandemic, 1918-1919 ,MESH: Retrospective Studies ,MESH: London ,medicine.disease ,United Kingdom ,MESH: Quantitative Trait Loci ,MESH: Prospective Studies ,030227 psychiatry ,MESH: France ,Case register ,MESH: Suicide ,MESH: Pneumonia, Viral ,[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health ,Matched group ,RC0321 ,MESH: Resilience, Psychological ,business ,030217 neurology & neurosurgery - Abstract
Background: Unipolar mania is a putative subtype of bipolar disorder (BD) in which individuals experience recurrent manic but not major depressive episodes. Few studies of unipolar mania have been conducted in developed countries and none in the UK. This study aimed to identify and characterise people with unipolar mania in the UK and France. \ud \ud Methods: People with unipolar mania were ascertained using a South London UK electronic case register and a French BD case series. Each unipolar mania group was compared to a matched group of people with BD who have experienced depressive episodes. \ud \ud Results: 17 people with unipolar mania were identified in South London and 13 in France. The frequency of unipolar mania as a percentage of the BD clinical population was 1.2% for the South London cohort and 3.3% for the French cohort. In both cohorts, people with unipolar mania experienced more manic episodes than people with BD, and in the French cohort were more likely to experience a psychotic illness onset and more psychiatric admissions. Treatment characteristics of people with unipolar mania were similar to people with BD except that the unipolar mania group was less likely to be treated with antidepressants. \ud \ud Limitations: The relatively small number of people with unipolar mania identified by this study limits its power to detect differences in clinical variables. \ud \ud Conclusions: People with unipolar mania can be identified in France and the UK, and they may experience a higher frequency of manic episodes but have similar treatment characteristics to people with BD.
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- 2020
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