1. Neuro-hybrid system with spiking neural network and biomimetic ionic micro-stimulation
- Author
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Nishikawa, S. M., Khoyratee, F., Luo, Z., Shiraishi, T., Aihara, K., Yoshiho Ikeuchi, Kim, S. H., Fujii, T., Levi, T., Laboratoire de l'intégration, du matériau au système (IMS), Université Sciences et Technologies - Bordeaux 1-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS), Key Laboratory of Bio-resources and Eco-environment, ministry of education-College of Life Sciences-Sichuan University, Institute of Industrial Science (IIS), The University of Tokyo, Laboratory for Integrated Micro Mechatronics Systems (LIMMS), The University of Tokyo-Centre National de la Recherche Scientifique (CNRS), ministry of education-College of Life Sciences-Sichuan University [Chengdu] (SCU), The University of Tokyo (UTokyo), Centre National de la Recherche Scientifique (CNRS)-The University of Tokyo (UTokyo), and Levi, Timothée
- Subjects
[SPI]Engineering Sciences [physics] ,micro-stimulation ,[SPI] Engineering Sciences [physics] ,Neuro-hybrid ,Spiking Neural Network ,microfluidic ,biomimetic - Abstract
International audience; Millions of people worldwide have neurodegenerative diseases that influence one's cognitive and/or motor functions. To bring neuroprosthesis into realization and for future long-term replacement of damaged brain areas with artificial devices, investigations on the interaction of neuronal cell assemblies are essential. To circumvent the limitations, we propose a new bio-hybrid system which includes a real-time Spiking Neural Network (SNN) and a biomimetic ionic micro-stimulation coupled to living in vitro neuron culture. This system characterizes the neural network and its evolution by using biomimetic spike-timing based ionic stimulation.