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Free radicals have taken a firm place among the explanatory principles of the onset and development of tumors. Unambiguous ideas about the role of these highly active agents in carcinogenesis have not yet been obtained. The experimental results are contradictory, often the opposite. The field of study of the value of the activity of antioxidant systems based on the results obtained is no less controversial. In this regard, the urgent problem is the need to prescribe antioxidants in oncology. Antitumor effects of antioxidants are being questioned in many works, which brings to the forefront the appropriateness and adequacy of their appointment. The ambiguous role of free radicals in carcinogenesis determines the development of therapeutic strategies based on the precise modulation of oxidative processes.

The article analyzes the results of a randomized multicenter studies devoted to elucidate the role of adjuvant and neoadjuvant chemotherapy, targeted therapy, adjuvant chemoradiation therapy in improving the results of surgical treatment of gastric cancer.

In the article are the incidence of breast cancer, cervical and ovarian cancer in the Republic of Bashkortostan from 1993 to 2002 and from 2003 to 2012 analyzed. A comparative analysis of the performance of the primary cancer incidence neoplasms of the female reproductive system has done, level patterns the dynamics of disease in different years, depending on age are obtained.

The article analyzes the incidence of prostate cancer in the Republic of Bashkortostan from 1993 to 2002 and from 2003 to 2012, the levels of the primary disease, the patterns of the level, dynamics of morbidity in different years depending on age.