1. 3 个不同条目版本中医体质量表的最小临床重要差值研究.
- Author
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朱燕波, 丛建妮, and 史会梅
- Subjects
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CHINESE medicine , *INTEGERS , *CLINICAL medicine , *ACUPUNCTURE points , *DISEASE susceptibility - Abstract
Objective We aimed to determine the minimum clinically important difference (MCID) of three different item versions of the Constitution in Chinese Medicine Questionnaire (CCMQ), to facilitate the clinical application of CCMQ. Methods In total, 537 subjects were included in the analysis. All subjects voluntarily completed a comprehensive of traditional Chinese medicine ( TCM) constitution intervention (mood, diet, daily living, exercise, and acupoints). The subjects filled out the 60-item CCMQ and the Short Form Health Questionnaire (SF-36) at baseline and 3 months after the intervention. The result of the 41-item and the 30-item CCMQ were scored according to the result of the 60-item CCMQ. An anchor-based approach and a distribution-based approach were used to estimate the MCID of the three versions of the CCMQ. The anchor of the anchor-based approach was SF-36 item 1, and the analysis method were the mean change method and multiple linear regression. The standardized response mean ( SRM) was used for the distribution-based approach. Results The mean change method and multiple linear regression estimation result were averaged and rounded to whole numbers. The MCID values of the 60-item CCMQ of balanced type, qi-deficiency type, yang-deficiency type, yin-deficiency type, phlegm-dampness type, dampness-heat type, blood-stasis type, qi-depression type, and special diathesis type were 5, -5, -3, -3, -4, -4, -4, -4, and -2, respectively. The MCID values of the 41-item CCMQ were 4, -6, -4, -2, -4, -4, -4, -4, and -2, respectively. The MCID values of the 30-item CCMQ were 5, - 5, - 4, - 3, - 4, - 5, - 4, - 5, and - 2, respectively. The MCID values estimated by the anchor-based approach were higher than those estimated when SRM was 0. 2, except for the special diathesis type. Conclusion The MCID values of three different versions of the CCMQ estimated in this study can reflect the minimum score change of the CCMQ considered important and meaningful by patients, which is helpful for doctors in explaining the effect of TCM constitution intervention or setting intervention targets. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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