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Objective To investigate the impact of diverse health education on patients' quality of life and anxiety after periodontally accelerated osteogenic orthodontics ( PAOO) surgery, providing clinical evidence for exploring better health education models. Methods Patients who visited the Orthodontics Department of Kunming Medical University's Affiliated Stomatology Hospital and required PAOO surgery from April 2022 to December 2023 were selected for this study. They were randomly assigned into a control group and an experimental group, each consisting of 42 patients. The control group received standard health education, which included preoperative verbal guidance, intraoperative communication, and postoperative instructions. In contrast, the experimental group, in addition to the regular health education, had a diversified health education group established, providing one-onone guidance during the perisurgical period. Anxiety ( SAS, MDAS), pain ( VAS), postoperative clinical manifestations (such as bleeding, nausea, sleep issues, etc.), self-management efficacy for oral health (SESS), and dental plaque index (PLI) were assessed and compared between the two groups before and after surgery. Before and after the PAOO surgery, comparisons were also made regarding anxiety, fear, pain, quality of life, and selfmanagement abilities for oral health between the two groups. Results The patients in the observation group had significantly lower SAS scores three days post-surgery compared to the control group, with MDAS scores also showing a significant decrease ( P < 0.001) . Seven days post-surgery, the VAS scores indicated a significant reduction in the observation group compared to the control group (P < 0.001). The level of post-operative bleeding and nausea in the observation group was significantly lower than in the control group (P < 0.001). Additionally, the self-efficacy regarding oral health in the observation group significantly improved one month after surgery ( P < 0.001), with a notable reduction in the plaque index (P < 0.05). In terms of quality of life, the overall quality of life scores for the observation group were significantly higher than those for the control group one month after surgery (P < 0.001). Conclusion In the perioperative care of PAOO, incorporating diverse health education measures can effectively reduce patient discomfort, alleviate anxiety, and improve patients' quality of life during the perioperative period as well as their ability to manage oral health independently. [ABSTRACT FROM AUTHOR]