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Objective: To retrospectively analyze the clinical efficacy of laparoscopic uterine vascular occlusion combined with hysteromyoma enucleation in the treatment of hysteromyoma. Methods: The clinical data of patients with hysteromyoma who treated in our hospital from June 2017 to July 2019 were analyzed (n=150). According to different surgical methods, the patients were divided into group A (laparoscopic hysteromyoma enucleation treatment, 73 cases) and group B (laparoscopic uterine vascular occlusion combined with hysteromyoma enucleation treatment, 77 cases). The intraoperative, endocrine hormones, postoperative recovery indexes, pregnancy situation, complication rate and recurrence rate were compared between the two groups. Results: There was no statistical difference in the operative time between the two groups (P>0.05), the intraoperative blood loss in group B was less than that in group A, and the postoperative exhaust time, hospitalization days and out of bed activity time were shorter than those in group A (P<0.05). There were no significant differences in the levels of luteinizing hormone (LH), follicle stimulating hormone (FSH) and estradiol (E2) in group A at before surgery, 3 months after surgery and 6 months after surgery (P>0.05). In group B, the level of E2decreased and then increased before surgery, 3 months after surgery and 6 months after surgery, while the levels of LH and FSH increased and then decreased (P<0.05). The levels of LH and FSH in group B were higher than those in group A, and the level of E2was lower than that in group A at 3months after surgery (P<0.05). Compared with group A, the complication rate in group B was significantly decreased, and the difference between groups was statistically significant (P<0.05). The pregnancy rate in group B was higher than that in group A, and the recurrence rate of hysteromyoma was lower than that in group A (P<0.05). There was no significant difference in abortion rate between the two groups (P>0.05). Conclusion: Compared with simple hysteromyoma enucleation, the treatment of hysteromyoma patients combined with laparoscopic uterine vascular occlusion can reduce the intraoperative blood loss, promote the postoperative recovery of patients, and reduce the complication rate and recurrence rate. Although it has a slight and transient impact on ovarian function, it can recover gradually and improve the pregnancy rate. [ABSTRACT FROM AUTHOR]

To investigate the effects of laparoscopic myomectomy and laparotomy on endocrine status, immune function and prognosis of patients with uterine fibroids. From January 2014 to January 2019, 90 patients with hysteromyoma in our hospital were selected, they were divided into group A (n=44) and group B (n=46) according to the different operation methods. Group A received laparotomy, and group B received laparoscopic hysteromyomectomy. The clinical indexes, endocrine status, immune function, complications and prognosis of the two groups were compared. There was no statistical difference in the operation time between the two groups (P>0.05). The intraoperative hemorrhage in group B was less than that in group A, and the hospitalization time and recovery time of anal exhaust after operation were shorter than those in group A (P<0.05). Follicular stimulating hormone (FSH) and luteinizing hormone (LH) in both groups at 1 month after operation were increased than before operation, and estradiol (E2) was decreased than before operation (P<0.05). FSH and LH in group B at 1 month after operation were lower that in group A, and E2 was higher than that in group A (P<0.05). CD3+, CD4+, CD4+ /CD8+ in both groups at 1d after operation were lower than before operation, but the group B were higher than group A (P<0.05). CD8+ was higher than before operation, but the group B were lower than group A (P<0.05). The incidence of complications in group B was lower than that in group A (P<0.05). There were no significant differences between the two groups in the normal rate of uterine morphology, the recurrence rate and the normal rate of menstrual transition (P>0.05). Compared with laparotomy, laparoscopic myomectomy can significantly reduce the damage to the endocrine state and immune function of patients with hysteromyoma, promote the postoperative recovery of patients, reduce the incidence of complications, and at the same time, it can obtain the same short-term prognosis as laparotomy. [ABSTRACT FROM AUTHOR]

目的探讨快速护理流程在腹腔镜子宫肌瘤剔除术中的应用价值。方法选取郑州市妇幼保健院2017年4月 至2018年4月行腹腔镜下子宫肌瘤剔除术患者84例，按随机数字表法分为对照组与研究组，每组42例，比较2组术后恢复情况 和术后并发症发生情况。结果研究组患者术后肛门恢复排气时间、正常进食恢复时间及住院时间均短于对照组，且术后并发症 发生率低于对照组，差异均有统计学意义（PsO. 05)。结论快速护理流程能促进腹腔镜子宫肌瘤剔除术患者术后恢复，减少术 后并发症的发生，值得临床推广。 [ABSTRACT FROM AUTHOR]

目的探讨腹腔镜子宫肌瘤剥除术对子宫肌瘤患者术后生活质量及复发率的影响。方法选取该院 收治的子宫肌瘤患者88 例，按随机数字表法分为对照组和观察组，对照组行常规开腹手术，观察组行腹腔镜子宫肌瘤 剥除术，采用视觉模拟疼痛量表（VAS）及简易健康状况量表（SF-36）对两组疼痛程度及生活质量进行评分，并观察两组 手术时间、术中出血量、术后排气时间及住院时间，术后1 年随访两组妊娠率及复发率。结果治疗后，观察组VAS 评 分低于对照组，差异有统计学意义（P<0.05）；治疗后，观察组SF-36 评分高于对照组，差异有统计学意义（P<0.05）；观察 组手术时间、术后排气时间、住院时间及术中出血量优于对照组，差异有统计学意义（P<0.05）；术后随访1 年，观察组妊 娠率高于对照组，差异有统计学意义（P<0.05）；观察组复发率低于对照组，差异有统计学意义（P<0.05）。结论采用腹 腔镜子宫肌瘤剥除术治疗子宫肌瘤能有效减少术中出血量，缓解患者疼痛程度，缩短手术时间、术后排气时间及住院时 间，降低复发率，提高患者生活质量和术后妊娠率。 [ABSTRACT FROM AUTHOR]

目的　评价大孕周子宫肌瘤(子宫体积≥14孕周)患者术前使用促性腺激素释放激素激动剂(ＧｎＲＨ-ａ) 的疗效及术后继续使用ＧｎＲＨ-ａ对子宫肌瘤复发情况的影响。方法　将择期手术、子宫体积≥14孕周的子宫肌 瘤患者纳为观察组(ｎ=25)，术前行ＧｎＲＨ-ａ皮下注射，3.6ｍｇ/次，隔28ｄ注射1次，共治疗2次，停药后2周行腹 腔镜手术；将同期行腹腔镜手术、子宫体积10～12孕周的子宫肌瘤患者纳为对照组(ｎ=36)。统计观察组预治疗 前后患者子宫及肌瘤体积、血红蛋白的变化，对比观察组和对照组手术时间、术中出血量、输血率。将接受腹腔镜 手术后的观察组和对照组随机各分为两亚组分别为Ａ1(ｎ=14)、Ａ2(ｎ=11)、Ｂ1(ｎ=20)、Ｂ2(ｎ=16)组，给予Ａ1、 Ｂ1组ＧｎＲＨ-ａ治疗，具体用法及剂量同上；Ａ2、Ｂ2组不做处理，随访统计各组术后15ｄ、6个月、9个月、12个月子宫 体积、肌瘤复发情况。结果　观察组术前给予ＧｎＲＨ-ａ预处理后子宫及肌瘤体积显著缩小，血红蛋白明显升高(Ｐ 均<0.05)；患者均完成腹腔镜下子宫肌瘤剔除术，无一中转开腹，观察组手术时间、术中出血量及输血例数均较对 照组明显减少(Ｐ均<0.05)；术后6、9、12个月Ａ1组子宫体积与Ａ2、Ｂ1、Ｂ2组比较差异有统计学意义(Ｐ均<0. 05)；术后随访12个月，Ａ1组子宫肌瘤复发率较其他治疗组明显降低(Ｐ均<0.05)。结论　术前应用2个疗程 的ＧｎＲＨ-ａ可明显缩小大孕周子宫肌瘤患者的子宫及肌瘤体积，提高血红蛋白水平，使腹腔镜手术得以实现，同时 术后继续应用可降低腹腔镜子宫肌瘤剔除术后肌瘤复发率。 [ABSTRACT FROM AUTHOR]