1. Assessment of Success Rate of Directly Observed Treatment Short-Course (DOTS) in Tuberculosis Patients of South India
- Author
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Raja D, Bhaskara Rao N, Siva Reddy Challa, Sivasankaran Ponnusankar, Basaveswara Rao Mv, Roopa Satyanarayan Basutkar, Divya P, Hema Manogna Narne, Ramakrishna Prudhivi, Sangram Das, and Veena G
- Subjects
0106 biological sciences ,medicine.medical_specialty ,Tuberculosis ,business.industry ,Mortality rate ,Medical record ,Treatment outcome ,010607 zoology ,Retrospective cohort study ,medicine.disease ,01 natural sciences ,Multivariate logistic regression model ,010602 entomology ,Internal medicine ,medicine ,Short course ,General Pharmacology, Toxicology and Pharmaceutics ,Infectious disease (athletes) ,business - Abstract
Objective: To assess the success rate of DOTS for tuberculosis patients and the secondary objective was to identify the factors associated with unsuccessful treatment outcome. Methods: A retrospective study was conducted to review the medical records of patients (n = 1113) registered at the Directly Observed Treatment Short-Course (DOTS) clinic of Government Infectious Disease (Govt. ID) Hospital, Guntur, India. Multivariate logistic regression model was used to determine the factors associated with the treatment success rate. Results: The overall mean success rate of TB patients was found to be 82.8%. Treatment success rate (TSR) was steadily increased across the years from 73.9% in 2015 to 84.3% in 2016 and 88.9% in 2017 while the death rate was steadily decreased from 11.2% in 2015 to 6.25% in 2016 and 4.33% in 2017. Risk factors significantly associated with unsuccessful treatment outcome were found to be HIV positive (P Key words: Directly observed treatment short-course, Retrospective study, Risk factors, Treatment success rate, Tuberculosis.
- Published
- 2018
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